SPBC146.04

Gene Standard NameUnassigned ChromosomeII
Systematic IDSPBC146.04 Gene Start1007901
Synonyms Gene End1008710
Productsulfhydryl oxidase (predicted) Gene Length810
Feature Typeprotein coding CDS Start1008018
Name Description CDS End1008596
Characterisation Statusbiological_role_inferred CDS Length579

Ensembl Gene Location
  1. SPBC146.02
  2. SPNCRNA.1403
  3. cut3
  4. SPBC146.04
  5. cwf25
  6. SPNCRNA.1404
  7. fan1
  8. prp2
  9. SPNCRNA.1405
  10. SPBC146.08c
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPBC146.04delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0003756protein disulfide isomerase activityISOSGD:S000006241GO_REF:0000024
GO:0016971flavin-linked sulfhydryl oxidase activityISSUniProtKB:P12284GO_REF:0000001
GO:0016972thiol oxidase activityISOSGD:S000006241GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005737cytoplasmIDAPMID:16823372
GO:0005789endoplasmic reticulum membraneISSUniProtKB:P38312GO_REF:0000001
GO:0005829cytosolIDAPMID:16823372
GO:0016021integral to membraneIEAUniProtKB:KW-0812GO_REF:0000037
GO:0030134ER to Golgi transport vesicleISOSGD:S000346142GO_REF:0000024
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
110079011008710

References

Region Start End Reference
five_prime_UTR10079011008017PMID:21511999
five_prime_UTR10079011008017PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF04777 IPR006863 Pfam Erv1/Alr 72 162 2
TMhelix TMHMM 7 29 955
PS51324 IPR017905 Prosite Profiles ERV/ALR sulphydryl oxidase 61 162 2
G3DSA:1.20.120.310 IPR006863 Gene3D 30 167 2
SSF69000 IPR006863 SuperFamily 71 166 2
PTHR12645 hmmpanther 1 189 2
PTHR12645:SF0 hmmpanther 1 189 2

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReference
SO:0001812transmembrane_helix

Protein Properties

Ave. residue weight 116.61 Da
Charge 2.50
Isoelectric point 7.20
Molecular weight 22.39 kDa
Number of residues 192
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1.1PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.29PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ste20Rictor homolog, Ste20 Negative GeneticPMID:22681890
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:22681890
sdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Positive GeneticPMID:22681890
hrq1RecQ type DNA helicase Hrq1 (predicted) Positive GeneticPMID:22681890
tor1phosphatidylinositol kinase Tor1 Negative GeneticPMID:22681890
hrp3ATP-dependent DNA helicase Hrp3 Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPBC146.04 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC146.04 Retrieval of eukaryotic orthologs
BioGrid SPBC146.04 BioGRID Interaction Datasets
Bähler Lab SPBC146.04 Cell Cycle Expression Profile
Bähler Lab SPBC146.04 Meiosis/Sporulation Expression Profies
Bähler Lab SPBC146.04 Pheromone response/mating expression profiles
Bähler Lab SPBC146.04 Environmental stress expression profiles
Bähler Lab SPBC146.04 Bähler Lab Transcriptome Viewer
Cyclebase SPBC146.04 Cell Cycle Data
PInt SPBC146.04 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC146.04 Entrez Gene
WikiGene2539721sulfhydryl oxidase (predicted)
Uniprot_genenameERV2
EntrezGene2539721sulfhydryl oxidase (predicted)
SPD / RIKEN06/06C05Orfeome Localization Data
UniProtKB/SwissProtQ9Y806FAD-linked sulfhydryl oxidase erv2
ModBaseQ9Y806Database of comparative protein structure models
Pfam Protein DomainsQ9Y806Pfam Domain Arrangement
RefSeq PeptideNP_595393sulfhydryl oxidase (predicted)
RefSeq mRNANM_001021300972h- sulfhydryl oxidase (predicted) (SPBC146.04), mRNA
European Nucleotide ArchiveCAB46757ENA Protein Mapping
UniParcUPI000006B1B2UniProt Archive

Literature for SPBC146.04
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013