meu17 (SPBC14C8.05c)

Gene Standard Namemeu17 Characterisation Statuspublished
Systematic IDSPBC14C8.05c Feature Typeprotein coding
Synonyms Name DescriptionMeiotic Expression Upregulated
Productglucan-alpha-1,4-glucosidase Product Size450aa, 51.16 kDa
Genomic Location Chromosome II, 2213495-2211798 (1698nt); CDS:2213372-2212020 (1353nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0004339glucan 1,4-alpha-glucosidase activityISOSGD:S000001361GO_REF:00000241
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0030437ascospore formationISOSGD:S000001361GO_REF:000002499
GO:0005980glycogen catabolic processISOSGD:S000001361GO_REF:00000241
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005794Golgi apparatusIDAPMID:16823372355
GO:0009986cell surfaceNASGO_REF:0000001100
GO:0005783endoplasmic reticulumIDAPMID:16823372594
GO:0005628prospore membraneIDAPMID:1682337223
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001701sensitive to bortezomibCell growth assaymeu17ΔNullPECO:0000005, PECO:0000137PMID:21760946256
expressivity FYPO_EXT:0000001
FYPO:0002060viable vegetative cell populationMicroscopymeu17ΔNullPECO:0000005, PECO:0000137PMID:236978063755

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000054abnormal microtubule cytoskeleton organizationnot recorded (overexpression)PMID:1579792544
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopymeu17ΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Start End Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00723 Pfam IPR011613 Glycoside hydrolase family 15 41 440 2
G3DSA: Gene3D IPR012341 25 446 7
SSF48208 SuperFamily IPR008928 24 446 9
Low complexity (SEG) seg 345 356
PR00736 PRINTS IPR000165 Glucoamylase 308 327 1
PR00736 PRINTS IPR000165 Glucoamylase 131 148 1
PR00736 PRINTS IPR000165 Glucoamylase 197 215 1
PR00736 PRINTS IPR000165 Glucoamylase 395 416 1
PR00736 PRINTS IPR000165 Glucoamylase 428 443 1
PR00736 PRINTS IPR000165 Glucoamylase 59 76 1
PR00736 PRINTS IPR000165 Glucoamylase 149 168 1
SignalP-noTM signalp 1 16 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount

Protein Properties

Ave. residue weight 113.70 Da
Charge -11.00
Isoelectric point 4.94
Molecular weight 51.16 kDa
Number of residues 450
Gene Expression

Qualitative Gene Expression

RNA levelincreasedexperimental evidencePMID:11376151
during GO:0007126

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
NDduring GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.049during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
0.022during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3080
conserved in fungi4564
conserved in bacteria1001

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
sre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:21504829
External References
Database Identifier Description
NBRP SPBC14C8.05c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC14C8.05c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC14C8.05c BioGRID Interaction Datasets
Expression Viewer SPBC14C8.05c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC14C8.05c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC14C8.05c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC14C8.05c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC14C8.05c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC14C8.05c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC14C8.05c Cell Cycle Data
GEO SPBC14C8.05c GEO profiles
PInt SPBC14C8.05c Protein-Protein Interaction Predictor (Bähler Lab)
IntEnz3.2.1.3Integrated relational Enzyme database
Rhea3.2.1.3Annotated reactions database
SPD / RIKEN21/21A04Orfeome Localization Data
UniProtKB/SwissProtO60087Probable glucoamylase
ModBaseO60087Database of comparative protein structure models
StringO60087Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595908glucan-alpha-1,4-glucosidase
RefSeq mRNANM_001021816972h- glucan-alpha-1,4-glucosidase (meu17), mRNA
European Nucleotide ArchiveBAB60870ENA Protein Mapping
European Nucleotide ArchiveCAA18423ENA Protein Mapping
UniParcUPI0000125A82UniProt Archive

Literature for meu17

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014