tts1 (SPBC1539.04)

Gene Standard Nametts1 ChromosomeII
Systematic IDSPBC1539.04 Gene Start4368286
Synonyms Gene End4369816
Producttetra spanning protein 1, Tts1 Gene Length1531
Feature Typeprotein coding CDS Start4368389
Name DescriptionTeTra Spanning protein CDS End4369414
Characterisation Statuspublished CDS Length1026

Ensembl Gene Location
  1. sid4
  2. SPBC1539.01c
  3. SPBC1539.02
  4. SPBC1539.03c
  5. SPNCRNA.1688
  6. SPNCRNA.442
  7. tts1
  8. cog3
  9. SPBC1539.06
  10. SPBC1539.07c
  11. arf6
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000032abnormal cytokinesisno_name (unrecorded)unrecordedPMID:20434336
FYPO:0002060viable vegetative cell populationMicroscopytts1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005515protein bindingIPISPBC651.13cPMID:20434336
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0007105cytokinesis, site selectionIMPPMID:20434336
GO:0033554cellular response to stressIEPPMID:12529438
GO:0034613cellular protein localization
has_input rtn1IMPPMID:20434336
GO:0071786endoplasmic reticulum tubular network organization
occurs_in cell cortexIMPPMID:20434336
GO:0071790establishment of spindle pole body localization to nuclear envelopeIGIcut11PMID:20434336
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0000139Golgi membraneIEASL-0134GO_REF:0000039
GO:0005635nuclear envelopeIDAPMID:20434336
GO:0005783endoplasmic reticulumIDAPMID:16823372
GO:0005789endoplasmic reticulum membraneIEASL-0097GO_REF:0000039
GO:0005794Golgi apparatusIDAPMID:16823372
GO:0016021integral to membraneISSTMHMMGO_REF:0000024
GO:0031965nuclear membraneIEASL-0182GO_REF:0000039
GO:0032153cell division site
exists_during mitotic cell cycleIDAPMID:8873452
GO:0032541cortical endoplasmic reticulumIDAPMID:20434336
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
143682864368448
243686354369816

References

Region Start End Reference
three_prime_UTR43694154369816PMID:21511999
three_prime_UTR43694154369816PMID:21511999
five_prime_UTR43682864368388PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF03661 IPR005344 Pfam Uncharacterised protein family UPF0121 25 256 1
TMhelix TMHMM 25 47 955
TMhelix TMHMM 57 79 955
TMhelix TMHMM 170 192 955
TMhelix TMHMM 100 122 955
PTHR12703:SF0 hmmpanther 1 273 1
PTHR12703 hmmpanther 1 273 1

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReference
SO:0000418signal_peptide
SO:0001812transmembrane_helix

Protein Properties

Ave. residue weight 113.15 Da
Charge 25.00
Isoelectric point 11.09
Molecular weight 31.57 kDa
Number of residues 279
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide6577.81PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide7921.96PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.8PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide9.3PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
yop1ER membrane protein DP1/Yop1 Phenotypic EnhancementPMID:20434336
SPBC16G5.05cVAP family protein (predicted) Phenotypic SuppressionPMID:23041194
SPAC17C9.12VAP family protein (predicted) Phenotypic SuppressionPMID:23041194
rtn1reticulon-like protein Rtn1 Phenotypic EnhancementPMID:20434336
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
rtn1reticulon-like protein Rtn1 Co-purificationPMID:20434336
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External References
Database Identifier Description
NBRP SPBC1539.04 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1539.04 Retrieval of eukaryotic orthologs
BioGrid SPBC1539.04 BioGRID Interaction Datasets
Bähler Lab SPBC1539.04 Cell Cycle Expression Profile
Bähler Lab SPBC1539.04 Meiosis/Sporulation Expression Profies
Bähler Lab SPBC1539.04 Pheromone response/mating expression profiles
Bähler Lab SPBC1539.04 Environmental stress expression profiles
Bähler Lab SPBC1539.04 Bähler Lab Transcriptome Viewer
Cyclebase SPBC1539.04 Cell Cycle Data
PInt SPBC1539.04 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC1539.04 Entrez Gene
WikiGene2539923conserved eukaryotic protein
Uniprot_genenameTTS1
EntrezGene2539923conserved eukaryotic protein
SPD / RIKEN15/15D12Orfeome Localization Data
UniProtKB/SwissProtQ9Y7Z5Tetra-spanning protein 1
ModBaseQ9Y7Z5Database of comparative protein structure models
Pfam Protein DomainsQ9Y7Z5Pfam Domain Arrangement
RefSeq PeptideNP_596818conserved eukaryotic protein
RefSeq mRNANM_001023838972h- conserved eukaryotic protein (SPBC1539.04), mRNA
European Nucleotide ArchiveCAB51336ENA Protein Mapping
UniParcUPI000006AA70UniProt Archive

Literature for tts1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013