SPBC1677.03c

Gene Standard NameUnassigned ChromosomeII
Systematic IDSPBC1677.03c Gene Start3937872
Synonyms Gene End3935430
Productmitochondrial threonine ammonia-lyase (predicted) Gene Length2443
Feature Typeprotein coding CDS Start3937666
Name Description CDS End3935864
Characterisation Statusbiological_role_inferred CDS Length1803

Ensembl Gene Location
  1. ppr1
  2. mug158
  3. SPNCRNA.545
  4. SPNCRNA.1649
  5. prl20
  6. dpm3
  7. SPBC1677.03c
  8. SPRRNA.36
  9. SPBTRNAASP.04
  10. thi2
  11. sec9
  12. SPNCRNA.1650
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002061inviable vegetative cell populationMicroscopySPBC1677.03cdelta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0004794L-threonine ammonia-lyase activityISSUniProtKB:P00927GO_REF:0000001
GO:0030170pyridoxal phosphate bindingIEAIPR000634GO_REF:0000002
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0009097isoleucine biosynthetic processISSUniProtKB:P00927GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005737cytoplasmIDAPMID:16823372
GO:0005739mitochondrionISSUniProtKB:P00927GO_REF:0000001
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
139378723935430

References

Region Start End Reference
three_prime_UTR39358633935430PMID:21511999
three_prime_UTR39358633935430PMID:21511999
five_prime_UTR39378723937667PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00291 IPR001926 Pfam Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily 109 402 7
PF00585 IPR001721 Pfam Threonine dehydratase, C-terminal regulatory domain 415 504 1
PF00585 IPR001721 Pfam Threonine dehydratase, C-terminal regulatory domain 512 598 1
PS00165 IPR000634 Prosite Patterns Serine/threonine dehydratase, pyridoxal-phosphate-binding site 135 148 2
G3DSA:3.40.1020.10 Gene3D 482 599 1
G3DSA:3.40.50.1100 Gene3D 200 432 7
G3DSA:3.40.50.1100 Gene3D 112 199 7
SSF55021 SuperFamily 506 598 5
SSF53686 IPR001926 SuperFamily 103 451 7
PTHR10314:SF30 hmmpanther 32 600 1
PTHR10314 hmmpanther 32 600 7
TIGR01124 IPR005787 tigrfam Threonine dehydratase, biosynthetic 97 597 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.91 Da
Charge 13.00
Isoelectric point 8.62
Molecular weight 66.54 kDa
Number of residues 600
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide10649.17PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide20265.91PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.9PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide9.4PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in bacteria
conserved in metazoa
conserved in vertebrates
Manually curated orthologous groups
SpeciesGeneDescription

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External References
Database Identifier Description
NBRP SPBC1677.03c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1677.03c Retrieval of eukaryotic orthologs
BioGrid SPBC1677.03c BioGRID Interaction Datasets
Bähler Lab SPBC1677.03c Cell Cycle Expression Profile
Bähler Lab SPBC1677.03c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC1677.03c Pheromone response/mating expression profiles
Bähler Lab SPBC1677.03c Environmental stress expression profiles
Bähler Lab SPBC1677.03c Bähler Lab Transcriptome Viewer
Cyclebase SPBC1677.03c Cell Cycle Data
PInt SPBC1677.03c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC1677.03c Entrez Gene
KEGGMAP00260
IntEnz4.3.1.19
WikiGene2540162threonine ammonia-lyase
EntrezGene2540162threonine ammonia-lyase
SPD / RIKEN36/36E02Orfeome Localization Data
UniProtKB/SwissProtO94634Threonine dehydratase, mitochondrial
ModBaseO94634Database of comparative protein structure models
Pfam Protein DomainsO94634Pfam Domain Arrangement
RefSeq PeptideNP_596641threonine ammonia-lyase
RefSeq mRNANM_001022563972h- threonine ammonia-lyase (SPBC1677.03c), mRNA
European Nucleotide ArchiveCAB37622ENA Protein Mapping
UniParcUPI000006AD98UniProt Archive

Literature for SPBC1677.03c
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013