SPBC1683.05


Gene Standard NameUnassigned Characterisation Statusbiological role inferred
Systematic IDSPBC1683.05 Feature Typeprotein coding
Synonyms Name Description
Producturicil/uridine permese transmembrane transporter family (predicted) Product Size559aa, 62.67 kDa
Genomic Location Chromosome II, 147915-150574 (2660nt); CDS:148750-150429 (1680nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
transmembrane transporter activity289
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
amine transport13
Annotation ExtensionEvidenceWith/FromReference
transmembrane transport339
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Golgi apparatus357
Annotation ExtensionEvidenceWith/FromReference
integral component of membrane962
Annotation ExtensionEvidenceWith/FromReference
plasma membrane255
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
decreased vegetative cell population growthSPBC1683.05Δ657
resistance to hydroxyureaSPBC1683.05Δ18
sensitive to bleomycinSPBC1683.05Δ78
viable vegetative cell populationSPBC1683.05Δ3840

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologySPBC1683.05Δ3100
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons147915..150574
mRNA147915..150574
5' UTR147915..148749PMID:21511999
CDS148750..150429
3' UTR150430..150574PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02133 Pfam IPR001248 Purine-cytosine permease 59 504 3
TMhelix TMHMM 387 404 953
TMhelix TMHMM 348 367 953
TMhelix TMHMM 466 488 953
TMhelix TMHMM 102 124 953
TMhelix TMHMM 263 285 953
TMhelix TMHMM 229 251 953
TMhelix TMHMM 139 161 953
TMhelix TMHMM 300 322 953
TMhelix TMHMM 495 517 953
TMhelix TMHMM 411 433 953
TMhelix TMHMM 192 214 953
PTHR30618 HMMPANTHER 5 542 3
PTHR30618:SF10 HMMPANTHER 5 542 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.11 Da
Charge 9.50
Codon Adaptation Index 0.47
Isoelectric point 8.53
Molecular weight 62.67 kDa
Number of residues 559
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1676
present during mitotic M phaseS28
present during mitotic M phaseS26
present during mitotic M phaseS27
S26, S27
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S28 PMID:21712547
present during mitotic M phase experimental evidence S26 PMID:21712547
present during mitotic M phase experimental evidence S27 PMID:21712547
experimental evidence S27 PMID:24763107
experimental evidence S26 PMID:24763107
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for SPBC1683.05

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
8061.12during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.8during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
3.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Complementation
DescriptionQualifierReference
does not functionally complement S. cerevisiae thi7Non-traceable Author Statement
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4606
conserved in eukaryotes4516
conserved in bacteria1001
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPBC1683.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1683.05 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC1683.05 BioGRID Interaction Datasets
Expression Viewer SPBC1683.05 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC1683.05 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC1683.05 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC1683.05 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC1683.05 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC1683.05 Transcriptome Viewer (Bähler Lab)
GEO SPBC1683.05 GEO profiles
PInt SPBC1683.05 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC1683.05 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC1683.05 Fission yeast phenotypic data & analysis
Cyclebase SPBC1683.05.1 Cell Cycle Data
SPD / RIKEN35/35B06Orfeome Localization Data
UniProtKB/SwissProtQ9P6J5Uncharacterized permease C1683.05
ModBaseQ9P6J5Database of comparative protein structure models
STRINGQ9P6J5Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595061membrane transporter (predicted)
RefSeq mRNANM_001020967972h- membrane transporter (predicted) (SPBC1683.05), mRNA

Literature for SPBC1683.05

Search: Europe PMC or PubMed

Release Version: PomBase:30_59 - 12 Apr 2016