Gene Standard NameUnassigned Characterisation Statusbiological role inferred
Systematic IDSPBC1683.05 Feature Typeprotein coding
Synonyms Name Description
Producturicil/uridine permese transmembrane transporter family (predicted) Product Size559aa, 62.67 kDa
Genomic Location Chromosome II, 147915-150574 (2660nt); CDS:148750-150429 (1680nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
transmembrane transporter activity286
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
amine transport14
Annotation ExtensionEvidenceWith/FromReference
transmembrane transport361
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Golgi apparatus357
Annotation ExtensionEvidenceWith/FromReference
integral component of membrane967
Annotation ExtensionEvidenceWith/FromReference
plasma membrane250
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
decreased vegetative cell population growthSPBC1683.05Δ588
resistance to hydroxyureaSPBC1683.05Δ18
sensitive to bleomycinSPBC1683.05Δ77
viable vegetative cell populationSPBC1683.05Δ3815

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologySPBC1683.05Δ3095
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR147915..148749PMID:21511999
3' UTR150430..150574PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02133 Pfam IPR001248 Purine-cytosine permease 59 504 3
TMhelix TMHMM 387 404 959
TMhelix TMHMM 229 251 959
TMhelix TMHMM 102 124 959
TMhelix TMHMM 139 161 959
TMhelix TMHMM 348 367 959
TMhelix TMHMM 263 285 959
TMhelix TMHMM 495 517 959
TMhelix TMHMM 300 322 959
TMhelix TMHMM 411 433 959
TMhelix TMHMM 192 214 959
TMhelix TMHMM 466 488 959
PTHR30618 HMMPANTHER 50 540 3
PTHR30618:SF0 HMMPANTHER 50 540 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.11 Da
Charge 9.50
Codon Adpatation Index 0.47
Isoelectric point 8.53
Molecular weight 62.67 kDa
Number of residues 559

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1672
present during mitotic M phaseS28
present during mitotic M phaseS27
S26, S27
present during mitotic M phaseS26
Annotation ExtensionEvidenceResidueReference
experimental evidence S26 PMID:24763107
present during mitotic M phase experimental evidence S26 PMID:21712547
experimental evidence S27 PMID:24763107
present during mitotic M phase experimental evidence S27 PMID:21712547
present during mitotic M phase experimental evidence S28 PMID:21712547
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
8061.12during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.8during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
3.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
does not functionally complement S. cerevisiae thi7Non-traceable Author Statement
Taxonomic Conservation
conserved in fungi4604
conserved in eukaryotes4514
conserved in bacteria1000

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPBC1683.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1683.05 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC1683.05 BioGRID Interaction Datasets
Expression Viewer SPBC1683.05 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC1683.05 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC1683.05 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC1683.05 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC1683.05 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC1683.05 Transcriptome Viewer (Bähler Lab)
GEO SPBC1683.05 GEO profiles
PInt SPBC1683.05 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC1683.05 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC1683.05 Fission yeast phenotypic data & analysis
Cyclebase SPBC1683.05.1 Cell Cycle Data
SPD / RIKEN35/35B06Orfeome Localization Data
UniProtKB/SwissProtQ9P6J5Uncharacterized permease C1683.05
ModBaseQ9P6J5Database of comparative protein structure models
STRINGQ9P6J5Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595061membrane transporter (predicted)
RefSeq mRNANM_001020967972h- membrane transporter (predicted) (SPBC1683.05), mRNA
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveCAB91167ENA Protein Mapping
European Nucleotide ArchiveCAB91167.1ENA Protein Mapping
UniParcUPI000006B24BUniProt Archive

Literature for SPBC1683.05

Search: Europe PMC or PubMed

Release Version: PomBase:28_55 - 09 Sep 2015