SPBC1683.05


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPBC1683.05 Feature Typeprotein coding
Synonyms Name Description
Producturicil/uridine permese transmembrane transporter family (predicted) Product Size559aa, 62.67 kDa
Genomic Location Chromosome II, 147915-150574 (2660nt); CDS:148750-150429 (1680nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0015205nucleobase transmembrane transporter activityIEAIPR001248GO_REF:00000023
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0015837amine transportNASGO_REF:000005113
GO:0015851nucleobase transportIEAIPR001248GO_REF:00000023
GO:0055085transmembrane transportISMPFAM:PF02133GO_REF:0000024336
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005794Golgi apparatusIDAPMID:16823372355
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371018
GO:0005886plasma membraneISOSGD:S000004227GO_REF:0000024247
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopySPBC1683.05ΔNullPECO:0000005, PECO:0000137PMID:236978063759
MicroscopySPBC1683.05ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3089
penetrance FYPO_EXT:0000001MicroscopySPBC1683.05ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1147915150574

UTRs

Region Coordinates Reference
five_prime_UTR147915..148749PMID:21511999
three_prime_UTR150430..150574PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02133 Pfam IPR001248 Permease, cytosine/purines, uracil, thiamine, allantoin 59 504 3
TMhelix TMHMM 495 517 959
TMhelix TMHMM 466 488 959
TMhelix TMHMM 102 124 959
TMhelix TMHMM 229 251 959
TMhelix TMHMM 300 322 959
TMhelix TMHMM 263 285 959
TMhelix TMHMM 139 161 959
TMhelix TMHMM 411 433 959
TMhelix TMHMM 348 367 959
TMhelix TMHMM 192 214 959
TMhelix TMHMM 387 404 959
PTHR30618:SF0 HMMPANTHER 2 542 3
PTHR30618 HMMPANTHER 2 542 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.11 Da
Charge 9.50
Isoelectric point 8.53
Molecular weight 62.67 kDa
Number of residues 559
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineexperimental evidenceS26PMID:217125471670
present during mitotic M phase
present during mitotic M phaseexperimental evidenceS27PMID:21712547
present during mitotic M phaseexperimental evidenceS28PMID:21712547
experimental evidenceS26PMID:24763107
experimental evidenceS27PMID:24763107
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
8061.12during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.8during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
3.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Complementation
DescriptionQualifierReference
does not functionally complement S. cerevisiae thi7Non-traceable Author Statement
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4600
conserved in eukaryotes4514
conserved in bacteria1000
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPBC1683.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1683.05 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC1683.05 BioGRID Interaction Datasets
Expression Viewer SPBC1683.05 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC1683.05 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC1683.05 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC1683.05 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC1683.05 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC1683.05 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC1683.05 Cell Cycle Data
GEO SPBC1683.05 GEO profiles
PInt SPBC1683.05 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC1683.05 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC1683.05 Fission yeast phenotypic data & analysis
SPD / RIKEN35/35B06Orfeome Localization Data
UniProtKB/SwissProtQ9P6J5Uncharacterized permease C1683.05
ModBaseQ9P6J5Database of comparative protein structure models
STRINGQ9P6J5Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595061membrane transporter (predicted)
RefSeq mRNANM_001020967972h- membrane transporter (predicted) (SPBC1683.05), mRNA
European Nucleotide ArchiveCAB91167.1ENA Protein Mapping
UniParcUPI000006B24BUniProt Archive

Literature for SPBC1683.05

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014