eso1 (SPBC16A3.11)


Gene Standard Nameeso1 Characterisation Statuspublished
Systematic IDSPBC16A3.11 Feature Typeprotein coding
Synonyms Name Description
Productsister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Product Size872aa, 98.91 kDa
Genomic Location Chromosome II, 4279656-4276864 (2793nt); CDS:4279591-4276973 (2619nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
acetyltransferase activity37
Annotation ExtensionEvidenceWith/FromReference
damaged DNA binding18
Annotation ExtensionEvidenceWith/FromReference
DNA-directed DNA polymerase activity29
Annotation ExtensionEvidenceWith/FromReference
metal ion binding743
Annotation ExtensionEvidenceWith/FromReference
peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor1
Annotation ExtensionEvidenceWith/FromReference
protein binding859
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
DNA biosynthetic process25
Annotation ExtensionEvidenceWith/FromReference
establishment of mitotic sister chromatid cohesion3
Annotation ExtensionEvidenceWith/FromReference
peptidyl-lysine N6-acetylation1
Annotation ExtensionEvidenceWith/FromReference
positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric2
Annotation ExtensionEvidenceWith/FromReference
protein acetylation60
Annotation ExtensionEvidenceWith/FromReference
regulation of maintenance of mitotic sister chromatid cohesion5
Annotation ExtensionEvidenceWith/FromReference
translesion synthesis5
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
nuclear chromatin318
Annotation ExtensionEvidenceWith/FromReference
nuclear replication fork62
Annotation ExtensionEvidenceWith/FromReference
nucleus2696
Annotation ExtensionEvidenceWith/FromReference
site of double-strand break46
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationeso1-H17Not specified1438
eso1ΔNull
normal vegetative cell population growtheso1-H17Not specified738
normal vegetative cell population growth ratecatalytic site mutant (D147N)Endogenous70
sensitive to UV during vegetative growthcatalytic site mutant (D147N)Endogenous142

Cell Phenotype

Term NameAlleleExpressionCount
abnormal mitotic cell cycleeso1ΔNull834
abolished protein acetylation3
affecting psm3eso1-H17Not specified
decreased maintenance of protein localization to heterochromatin at centromere outer repeat2
affecting rad21eso1-H17Not specified
elongated vegetative cellunnamed (unrecorded)174
increased duration of DNA damage checkpoint during cellular response to UVcatalytic site mutant (D147N)Endogenous2
inviable elongated vegetative celleso1ΔNull401
inviable vegetative cell, abnormal cell shape, normal cell sizeeso1ΔNull199
mutatoreso1ΔNull13
normal protein localization to heterochromatin at centromere outer repeat3
affecting rad21eso1-H17Not specified
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4279656..4276864
mRNA4279656..4276864
5' UTR4279656..4279592AB039861
CDS4279591..4276973
3' UTR4276972..4276864AB039861
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF13878 Pfam IPR028005 N-acetyltransferase ESCO, zinc-finger 643 679 1
PF13880 Pfam IPR028009 N-acetyltransferase ESCO, acetyl-transferase domain 797 854 1
PF00817 Pfam IPR001126 DNA-repair protein, UmuC-like 32 253 3
PS50173 Prosite Profiles IPR017963 DNA-repair protein, UmuC-like, N-terminal 29 285 3
PTHR11076 HMMPANTHER 2 857 3
PTHR11076:SF11 HMMPANTHER 2 857 1
1.10.150.20 Gene3D 266 338 15
3.30.1490.100 Gene3D IPR017961 DNA polymerase, Y-family, little finger domain 343 453 3
3.30.70.270 Gene3D 110 171 16
3.30.70.270 Gene3D 208 264 16
SSF56672 SuperFamily 6 319 24
SSF100879 SuperFamily IPR017961 DNA polymerase, Y-family, little finger domain 341 449 3

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000137zinc finger proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000137
PBO:0000153zf-C2H2 typeTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000153

Protein Properties

Ave. residue weight 113.43 Da
Charge 10.00
Isoelectric point 7.79
Molecular weight 98.91 kDa
Number of residues 872
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1672
present during mitotic M phaseS505
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S505 PMID:21712547
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
801during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
518during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
479during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.5during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.39during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Genome Organisation
DescriptionQualifierReferenceCount
tandem fusion protein14
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4603
conserved in eukaryotes4514
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2501
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
binds DNA-binding domain construct withatg11autophagy protein Atg11 Two-hybridPMID:23695164
binds activation domain construct withpcn1PCNA Two-hybridPMID:22308326
binds DNA-binding domain construct withpds5mitotic cohesin-associated protein Pds5 Two-hybridPMID:11598020
binds activation domain construct withpds5mitotic cohesin-associated protein Pds5 Two-hybridPMID:11598020
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withaha1chaperone activator Aha1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withalg9mannosyltransferase complex subunit Alg9 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withalp16gamma tubulin complex subunit Alp16 Negative GeneticPMID:23050226
negative genetic interaction withalr1alanine racemase Alr1 Negative GeneticPMID:23050226
negative genetic interaction withapl5AP-3 adaptor complex subunit Apl5 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withapm3AP-3 adaptor complex subunit Apm3 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withare1acyl-coA-sterol acyltransferase Are1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withare2acyl-coA-sterol acyltransferase Are2 (predicted) Negative GeneticPMID:23050226
negative genetic interaction witharg12argininosuccinate synthase Arg12 Negative GeneticPMID:23050226
negative genetic interaction witharg3ornithine carbamoyltransferase Arg3 Negative GeneticPMID:23050226
negative genetic interaction witharp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:23050226
negative genetic interaction withash2Ash2-trithorax family protein Negative GeneticPMID:23050226
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:23050226
negative genetic interaction withatg1802WD repeat protein involved in autophagy Atg18b Negative GeneticPMID:23050226
negative genetic interaction withatg4Atg8 deconjugator Atg4 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withatp12mitochondrial F1-ATPase chaperone Atp12 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withatp14F1-ATPase subunit H (predicted) Negative GeneticPMID:23050226
negative genetic interaction withbqt2bouquet formation protein Bqt2 Negative GeneticPMID:23050226
rescuesbrc1BRCT domain protein Brc1 Phenotypic SuppressionPMID:15972456
negative genetic interaction withbtf3nascent polypeptide-associated complex beta subunit Negative GeneticPMID:23050226
negative genetic interaction withbud23rRNA (guanine) methyltransferase Bud23 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withcbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Negative GeneticPMID:23050226
synthetically rescued bycdc10MBF transcription factor complex subunit Cdc10 Synthetic RescuePMID:10779336
synthetically rescued bycdc20DNA polymerase epsilon catalytic subunit Pol2 Synthetic RescuePMID:10779336
negative genetic interaction withchl1ATP-dependent DNA helicase Chl1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withchp1chromodomain protein Chp1 Negative GeneticPMID:23050226
synthetically rescued bycig2G1/S-specific B-type cyclin Cig2 Synthetic RescuePMID:10779336
negative genetic interaction withclr1SHREC complex subunit Clr1 Negative GeneticPMID:23050226
negative genetic interaction withclr2chromatin silencing protein Clr2 Negative GeneticPMID:23050226
negative genetic interaction withclr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:23050226
rescued byclr6histone deacetylase (class I) Clr6 Phenotypic SuppressionPMID:21979813
negative genetic interaction withcsi1mitotic chromosome segregation protein Csi1 Negative GeneticPMID:23050226
negative genetic interaction withctf8DNA replication factor C complex subunit Ctf8 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withcti6histone deacetylase complex subunit Cti6 Negative GeneticPMID:23050226
negative genetic interaction withctr4copper transporter complex subunit Ctr4 Negative GeneticPMID:23050226
negative genetic interaction withcue2SMR domain protein, possibly involved in DNA repair and neddylation Negative GeneticPMID:23050226
negative genetic interaction withcwf11complexed with Cdc5 protein Cwf11 Negative GeneticPMID:23050226
negative genetic interaction withcwf16splicing factor Cwf16 Negative GeneticPMID:23050226
negative genetic interaction withcyp4cyclophilin family peptidyl-prolyl cis-trans isomerase Cyp4 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withcyt1cytochrome c1 Cyt1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:23050226
negative genetic interaction withdef1RNAPII degradation factor Def1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withdid2ESCRT III complex subunit Did2 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withdph1UBA domain protein Dph1 Negative GeneticPMID:23050226
negative genetic interaction withecm313-methyl-2-oxobutanoatehydroxymethyltransferase Ecm31 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withect1ethanolamine-phosphate cytidylyltransferase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withefc25Ras1 guanyl-nucleotide exchange factor Efc25 Negative GeneticPMID:23050226
negative genetic interaction withegd2nascent polypeptide-associated complex alpha subunit Egd2 Negative GeneticPMID:23050226
negative genetic interaction withepe1Jmjc domain chromatin associated protein Epe1 Negative GeneticPMID:23050226
negative genetic interaction witherf2palmitoyltransferase Erf2 Negative GeneticPMID:23050226
negative genetic interaction witherg28Erg28 protein (predicted) Negative GeneticPMID:23050226
negative genetic interaction witherv41COPII-coated vesicle component Erv41 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withest1telomerase regulator Est1 Negative GeneticPMID:23050226
negative genetic interaction withfap1L-pipecolate oxidase Negative GeneticPMID:23050226
negative genetic interaction withgcn1translation elongation regulator Gcn1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withgdh2NAD-dependent glutamate dehydrogenase Gdh2 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withggg1glutathione-specific gamma-glutamylcyclotransferase Ggg1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withght1hexose transmembrane transporter Ght1 Negative GeneticPMID:23050226
negative genetic interaction withght4hexose transmembrane transporter Ght4 Negative GeneticPMID:23050226
negative genetic interaction withght7hexose transmembrane transporter Ght7 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withgid5GID complex armadillo repeat subunit Gid5 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withgim1prefoldin subunit 6, Gim1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withglt1glutamate synthase Glt1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withgpd3glyceraldehyde 3-phosphate dehydrogenase Gpd3 Negative GeneticPMID:23050226
negative genetic interaction withgst1glutathione S-transferase Gst1 Negative GeneticPMID:23050226
synthetic growth defect withhsk1Dbf4(Dfp1)-dependent protein kinase Hsk1 Synthetic Growth DefectPMID:11359920
synthetic growth defect withhsk1Dbf4(Dfp1)-dependent protein kinase Hsk1 Synthetic Growth DefectPMID:20176980
phenotype enhanced bykpa1DinB translesion DNA repair polymerase, pol kappa Phenotypic EnhancementPMID:20453833
negative genetic interaction withlaf1Clr6 L associated factor 1 Laf1 Negative GeneticPMID:23050226
negative genetic interaction withlat1dihydrolipoamide S-acetyltransferase E2, Lat1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withleo1RNA polymerase II associated Paf1 complex (predicted) Negative GeneticPMID:23050226
negative genetic interaction withlos1karyopherin exportin T Los1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withlsb1Wiskott-Aldrich syndrome homolog binding protein Lsb1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withlsb5cortical component Lsb5 (predicted) Negative GeneticPMID:23050226
synthetically rescued bymad2mitotic spindle checkpoint protein Mad2 Synthetic RescuePMID:10779336
negative genetic interaction withmas5DNAJ domain protein Mas5 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withmbx2MADS-box transcription factor Pvg4 Negative GeneticPMID:23050226
negative genetic interaction withmei2RNA-binding protein involved in meiosis Mei2 Negative GeneticPMID:23050226
negative genetic interaction withmeu10GPI anchored cell surface protein involved in ascospore wall assembly Meu10 Negative GeneticPMID:23050226
negative genetic interaction withmfr1fizzy-related protein Mfr1 Negative GeneticPMID:23050226
negative genetic interaction withmhf1CENP-S ortholog, FANCM-MHF complex subunit Mhf1 Negative GeneticPMID:23050226
negative genetic interaction withmhf2CENP-X homolog, FANCM-MHF complex subunit Mhf2 Negative GeneticPMID:23050226
synthetic lethal withmis4adherin, cohesin loading factor Mis4 Synthetic LethalityPMID:10779336
negative genetic interaction withmit1SHREC complex ATP-dependent DNA helicase subunit Mit1 Negative GeneticPMID:23050226
negative genetic interaction withmlh1MutL family protein Mlh1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withmrs2magnesium ion transmembrane transporter Mrs2 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withmsd1mitotic-spindle disanchored Msd1 Negative GeneticPMID:23050226
negative genetic interaction withmsh6MutS protein homolog Negative GeneticPMID:23050226
negative genetic interaction withmst2histone acetyltransferase Mst2 Negative GeneticPMID:23050226
negative genetic interaction withmto2MT organizer Mto2 Negative GeneticPMID:23050226
negative genetic interaction withmug111major facilitator family transmembrane transporter Mug111 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withmug166Schizosaccharomyces specific protein Mug166 Negative GeneticPMID:23050226
negative genetic interaction withmug51variant protein kinase 19 family protein Negative GeneticPMID:23050226
negative genetic interaction withmyh1adenine DNA glycosylase Myh1 Negative GeneticPMID:23050226
synthetically rescued bynot3CCR4-Not complex subunit Not3/5 (predicted) Synthetic RescuePMID:23050226
negative genetic interaction withnts1Clr6 histone deacetylase complex subunit Nts1 Negative GeneticPMID:23050226
negative genetic interaction withnup60nucleoporin Nup60 Negative GeneticPMID:23050226
negative genetic interaction withnxt1mRNA export receptor Nxt1 Negative GeneticPMID:23050226
negative genetic interaction withomh3alpha-1,2-mannosyltransferase Omh3 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withpam17TIM23 translocase complex-associated motor subunit Pam17 (predicted) Negative GeneticPMID:23050226
synthetically rescued bypcn1PCNA Synthetic RescuePMID:10779336
synthetically rescued bypds5mitotic cohesin-associated protein Pds5 Synthetic RescuePMID:23050226
synthetically rescued bypds5mitotic cohesin-associated protein Pds5 Synthetic RescuePMID:11598020
negative genetic interaction withpho24-nitrophenylphosphatase Negative GeneticPMID:23050226
negative genetic interaction withpht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:23050226
negative genetic interaction withplp1thioredoxin fold protein Plp1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withpmc3mediator complex subunit Pmc3/Med27 Negative GeneticPMID:23050226
negative genetic interaction withppa3protein phosphatase type 2A Ppa1 Negative GeneticPMID:23050226
negative genetic interaction withppb1calcium-dependent serine/threonine protein phosphatase calcineurin A, catalytic subunit Ppb1 Negative GeneticPMID:23050226
negative genetic interaction withppk33serine/threonine protein kinase Ppk33 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withpsk1serine/threonine protein kinase Psk1 Negative GeneticPMID:23050226
rescued bypsm3mitotic cohesin complex subunit Psm3 Phenotypic SuppressionPMID:21979813
synthetically rescued bypsm3mitotic cohesin complex subunit Psm3 Synthetic RescuePMID:21979813
synthetically rescued bypsm3mitotic cohesin complex subunit Psm3 Synthetic RescuePMID:21300781
synthetic growth defect withpsm3mitotic cohesin complex subunit Psm3 Synthetic Growth DefectPMID:21300781
negative genetic interaction withpth2mitochondrial aminoacyl-tRNA hydrolase Pth2 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withpub2HECT-type ubiquitin-protein ligase E3 Pub2 Negative GeneticPMID:23050226
negative genetic interaction withpyp1tyrosine phosphatase Pyp1 Negative GeneticPMID:23050226
synthetic growth defect withrad16DNA repair endonuclease XPF Synthetic Growth DefectPMID:25293972
synthetic lethal withrad21mitotic cohesin complex, non-SMC subunit Rad21 (kleisin) Synthetic LethalityPMID:10779336
negative genetic interaction withrad26ATRIP, ATR checkpoint kinase regulatory subunit Rad26 Negative GeneticPMID:23050226
negative genetic interaction withrad8ubiquitin-protein ligase E3 Rad8 Negative GeneticPMID:23050226
phenotype enhanced byrad8ubiquitin-protein ligase E3 Rad8 Phenotypic EnhancementPMID:20453833
rescuesrad9checkpoint clamp complex protein Rad9 Phenotypic SuppressionPMID:17515930
negative genetic interaction withraf2Rik1-associated factor Raf2 Negative GeneticPMID:23050226
synthetic growth defect withraf2Rik1-associated factor Raf2 Synthetic Growth DefectPMID:23050226
synthetic growth defect withrdp1RNA-directed RNA polymerase Rdp1 Synthetic Growth DefectPMID:23050226
negative genetic interaction withrec7meiotic recombination protein Rec7 Negative GeneticPMID:23050226
synthetically rescued byrep1MBF transcription factor activator Rep1 Synthetic RescuePMID:10779336
synthetically rescued byres2MBF transcription factor complex subunit Res2 Synthetic RescuePMID:10779336
phenotype enhanced byrev1deoxycytidyl transferase Rev1 (predicted) Phenotypic EnhancementPMID:20453833
phenotype enhanced byrev3DNA polymerase zeta catalytic subunit Rev3 (predicted) Phenotypic EnhancementPMID:20453833
phenotype enhanced byrhp18Rad18 homolog ubiquitin protein ligase E3, Rhp18 Phenotypic EnhancementPMID:20453833
negative genetic interaction withrik1silencing protein Rik1 Negative GeneticPMID:23050226
synthetically rescued byrox3mediator complex subunit Med19/Rox3 Synthetic RescuePMID:23050226
negative genetic interaction withrpl270260S ribosomal protein L27 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withrpl320260S ribosomal protein L32 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withrpl360160S ribosomal protein L36 Negative GeneticPMID:23050226
negative genetic interaction withrpl380160S ribosomal protein L38 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withrpn1019S proteasome regulatory subunit Rpn10 Negative GeneticPMID:23050226
negative genetic interaction withrsp1random septum position protein Rsp1 Negative GeneticPMID:23050226
negative genetic interaction withsan1sir antagonist, ubiquitin-protein ligase E3 Negative GeneticPMID:23050226
negative genetic interaction withser3D-3 phosphoglycerate dehydrogenase Ser3 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withset13ribosome L32 lysine methyltransferase Set13 Negative GeneticPMID:23050226
negative genetic interaction withsfp47Ubp4 interactor Sfp47 Negative GeneticPMID:23050226
negative genetic interaction withsil1nucleotide exchange factor for the ER lumenal Hsp70 chaperone, Sil1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withsks2heat shock protein, ribosome associated molecular chaperone Sks2 Negative GeneticPMID:23050226
negative genetic interaction withspa2cell polarity protein Spa2 Negative GeneticPMID:23050226
negative genetic interaction withSPAC1039.02phosphoprotein phosphatase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC1039.08serine acetyltransferase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC1071.09cDNAJ domain protein, DNAJC9 family (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC11D3.02cELLA family acetyltransferase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC11G7.01serine-rich Schizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPAC12B10.15cribonuclease H2 complex subunit (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC15E1.10PI31 proteasome inhibitor (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC16E8.13ubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC17A2.11Schizosaccharomyces pombe specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPAC17H9.08mitochondrial coenzyme A transmembrane transporter (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC1F12.04cconserved fungal protein Negative GeneticPMID:23050226
negative genetic interaction withSPAC20H4.06cRNA-binding protein, involved in splicing (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC212.04cS. pombe specific DUF999 family protein 1 Negative GeneticPMID:23050226
negative genetic interaction withSPAC22H10.02conserved fungal protein Negative GeneticPMID:23050226
negative genetic interaction withSPAC23D3.12inorganic phosphate transmembrane transporter (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC23H3.15cSchizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPAC23H4.16cSchizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPAC24C9.08vacuolar carboxypeptidase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC29A4.02ctranslation elongation factor EF-1 gamma subunit Negative GeneticPMID:23050226
negative genetic interaction withSPAC30.02celongator complex associated protein Kti2 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC3C7.13cglucose-6-phosphate 1-dehydrogenase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC4H3.03cglucan 1,4-alpha-glucosidase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC4H3.04cUPF0103 family Negative GeneticPMID:23050226
negative genetic interaction withSPAC57A7.09E3 ubiquitin-protein ligase, human RNF family homolog Negative GeneticPMID:23050226
negative genetic interaction withSPAC630.06cconserved fungal protein Negative GeneticPMID:23050226
negative genetic interaction withSPAC6G9.15cSchizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPAC806.04cprotein-glutamate O-methyltransferase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAC869.09conserved fungal protein Negative GeneticPMID:23050226
negative genetic interaction withSPAC922.04Schizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPAC977.11CRCB domain protein Negative GeneticPMID:23050226
negative genetic interaction withSPAC9E9.05Schizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPACUNK4.09methyltransferase with rhodanese domain (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPAP27G11.16Schizosaccharomyces pombe specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPBC1105.01rRNA processing protein Rrp12-like (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBC11C11.11cATP helicase Irc3 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBC1271.03cNLI interacting factor family phosphatase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBC1271.05czf-AN1 type zinc finger protein Negative GeneticPMID:23050226
negative genetic interaction withSPBC1348.01S. pombe specific DUF999 protein family 5 Negative GeneticPMID:23050226
negative genetic interaction withSPBC13E7.03cRNA hairpin binding protein (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBC1683.06curidine ribohydrolase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBC16E9.15heat shock factor binding protein (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBC17D1.05Schizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPBC17G9.12chydrolase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBC19G7.04HMG box protein Negative GeneticPMID:23050226
negative genetic interaction withSPBC19G7.18cSchizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPBC20F10.02cDUF1741 family protein Negative GeneticPMID:23050226
negative genetic interaction withSPBC20F10.03conserved eukaryotic protein Negative GeneticPMID:23050226
negative genetic interaction withSPBC25B2.10Usp (universal stress protein) family protein Negative GeneticPMID:23050226
negative genetic interaction withSPBC25H2.09DUF1690 family protein Negative GeneticPMID:23050226
negative genetic interaction withSPBC30D10.05csepiapterin reductase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBC336.13cmitochondrial inner membrane peptidase complex catalytic subunit 2 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBC3B8.05diphthamide biosynthesis protein Dph1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBC409.19cmetaxin (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBC428.10Schizosaccharomyces pombe specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPBC651.04Schizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPBC83.17transcriptional coactivator, multiprotein bridging factor Mbf1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPBPB10D8.06ctransmembrane transporter (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPCC1183.02glutathione S-transferase, translational elongation factor eEF1 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPCC1259.08conserved fungal protein, DUF2457 family Negative GeneticPMID:23050226
negative genetic interaction withSPCC1450.03ribonucleoprotein (RNP) complex (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPCC18.02transmembrane transporter (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPCC569.05cspermidine family transmembrane transporter (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPCC584.16cSchizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPCC70.10Schizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withSPCC757.02cepimarase (predicted) Negative GeneticPMID:23050226
negative genetic interaction withSPCPB16A4.06cSchizosaccharomyces specific protein Negative GeneticPMID:23050226
negative genetic interaction withspf31DNAJ protein Spf31 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withspn6meiotic (sorulation) septin Spn6 Negative GeneticPMID:23050226
synthetically rescued byspt2non-specific DNA binding protein Spt2 (predicted) Synthetic RescuePMID:23050226
negative genetic interaction withspt2non-specific DNA binding protein Spt2 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withssb3DNA replication factor A subunit Ssb3 Negative GeneticPMID:23050226
negative genetic interaction withssu72phosphoric ester hydrolase Ssu72 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withstc1LIM-like protein linking chromatin modification to RNAi, Stc1 Negative GeneticPMID:23050226
negative genetic interaction withstr1siderophore-iron transmembrane transporter Str1 Negative GeneticPMID:23050226
negative genetic interaction withstt41-phosphatidylinositol 4-kinase Stt4 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withswi3replication fork protection complex subunit Swi3 Negative GeneticPMID:23050226
negative genetic interaction withswi6HP1 family chromodomain protein Swi6 Negative GeneticPMID:23050226
synthetic growth defect withswi6HP1 family chromodomain protein Swi6 Synthetic Growth DefectPMID:23050226
negative genetic interaction withsyj1inositol-polyphosphate 5-phosphatase (synaptojanin homolog 1) Negative GeneticPMID:23050226
negative genetic interaction withtea4tip elongation aberrant protein Tea4 Negative GeneticPMID:23050226
negative genetic interaction withtfb6holo TFIIH complex subunit Tfb6 Negative GeneticPMID:23050226
negative genetic interaction withtif213translation initiation factor eIF2 gamma subunit Negative GeneticPMID:23050226
negative genetic interaction withtif452translation initiation factor eIF4E, 4F complex E subunit isoform 2, stress response factor Negative GeneticPMID:23050226
negative genetic interaction withtip1CLIP170 family protein Tip1 Negative GeneticPMID:23050226
negative genetic interaction withtma19translationally controlled tumor protein homolog Tma19/Tpt1 Negative GeneticPMID:23050226
negative genetic interaction withtps2trehalose-phosphate synthase Tps2 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withubc15ubiquitin conjugating enzyme E2 Ubc15 Negative GeneticPMID:23050226
negative genetic interaction withubp9ubiquitin C-terminal hydrolase Ubp9 Negative GeneticPMID:23050226
negative genetic interaction withubr1N-end-recognizing protein, UBR ubiquitin-protein ligase E3 Ubr1 Negative GeneticPMID:23050226
negative genetic interaction withufd2ubiquitin-protein ligase E4 Ufd2 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withutp16U3 snoRNP-associated protein Utp16 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withvps3CORVET complex subunit, GTPase regulator Vps3 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withvps8WD repeat protein Vps8 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withvps901guanyl-nucleotide exchange factor Vps901 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withvsl1vacuolar SNARE Vsl1/Vam7 Negative GeneticPMID:23050226
negative genetic interaction withwis2cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Negative GeneticPMID:23050226
synthetically rescued bywpl1Wings apart-like homolog Wpl1 Synthetic RescuePMID:23050226
synthetically rescued bywpl1Wings apart-like homolog Wpl1 Synthetic RescuePMID:21300781
inviable in presence of overexpressedwpl1Wings apart-like homolog Wpl1 Dosage LethalityPMID:21300781
negative genetic interaction withyip3Rab GTPase binding involved in ER to Golgi vesicle transport Yip3 (predicted) Negative GeneticPMID:23050226
negative genetic interaction withynd1nucleoside diphosphatase Ynd1 Negative GeneticPMID:23050226
negative genetic interaction withzym1metallothionein Zym1 Negative GeneticPMID:23050226
External References
Database Identifier Description
NBRP SPBC16A3.11 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC16A3.11 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC16A3.11 BioGRID Interaction Datasets
Expression Viewer SPBC16A3.11 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC16A3.11 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC16A3.11 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC16A3.11 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC16A3.11 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC16A3.11 Transcriptome Viewer (Bähler Lab)
GEO SPBC16A3.11 GEO profiles
PInt SPBC16A3.11 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC16A3.11 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC16A3.11 Fission yeast phenotypic data & analysis
Cyclebase SPBC16A3.11.1 Cell Cycle Data
SPD / RIKEN38/38F08Orfeome Localization Data
IntEnz2.3.1.-Integrated relational Enzyme database
Rhea2.3.1.-Annotated reactions database
UniProtKB/SwissProtO42917N-acetyltransferase eso1
ModBaseO42917Database of comparative protein structure models
STRINGO42917Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596778sister chromatid cohesion protein/DNA polymerase eta Eso1
RefSeq mRNANM_001023799972h- sister chromatid cohesion protein/DNA polymerase eta Eso1 (eso1), mRNA
European Nucleotide ArchiveAB039861ENA EMBL mapping
European Nucleotide ArchiveCAA16862.1ENA Protein Mapping
KEGG_Enzyme00230+2.7.7.7Purine metabolism
KEGG_Enzyme00240+2.7.7.7Pyrimidine metabolism
UniParcUPI000012A1BDUniProt Archive

Literature for eso1

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015