psd1 (SPBC16E9.18)


Gene Standard Namepsd1 Characterisation Statuspublished
Systematic IDSPBC16E9.18 Feature Typeprotein coding
SynonymsSPBC1E8.01 Name Description
Productphosphatidylserine decarboxylase Psd1 Product Size437aa, 49.13 kDa
Genomic Location Chromosome II, 1955636-1957371 (1736nt); CDS:1955709-1957022 (1314nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
phosphatidylserine decarboxylase activity3
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
GO Cellular Component
Term NameCount
mitochondrial inner membrane166
Annotation ExtensionEvidenceWith/FromReference
mitochondrion761
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
normal growth on glucose carbon sourcepsd1ΔNull207
viable vegetative cell populationpsd1ΔNull3809

Cell Phenotype

Term NameAlleleExpressionCount
normal vegetative cell morphologypsd1ΔNull548
viable vegetative cell with normal cell morphologypsd1ΔNull3094
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons1955636..1957371
mRNA1955636..1957371PMID:19286980
5' UTR1955636..1955708PMID:21511999
CDS1955709..1957022PMID:19286980
3' UTR1957023..1957371PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02666 Pfam IPR003817 Phosphatidylserine decarboxylase-related 131 430 3
TMhelix TMHMM 30 52 959
PTHR10067 HMMPANTHER IPR003817 Phosphatidylserine decarboxylase-related 39 433 3
TIGR00163 tigrfam IPR003817 Phosphatidylserine decarboxylase-related 118 430 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.42 Da
Charge 22.50
Isoelectric point 9.95
Molecular weight 49.13 kDa
Number of residues 437
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3258during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
3113during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
851.73during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
3112during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.7during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.66during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4603
conserved in eukaryotes4514
conserved in bacteria1001
conserved in metazoa3424
conserved in vertebrates3399
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPBC16E9.18 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC16E9.18 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC16E9.18 BioGRID Interaction Datasets
Expression Viewer SPBC16E9.18 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC16E9.18 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC16E9.18 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC16E9.18 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC16E9.18 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC16E9.18 Transcriptome Viewer (Bähler Lab)
GEO SPBC16E9.18 GEO profiles
PInt SPBC16E9.18 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC16E9.18 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC16E9.18 Fission yeast phenotypic data & analysis
Cyclebase SPBC16E9.18.1 Cell Cycle Data
IntEnz4.1.1.65Integrated relational Enzyme database
Rhea4.1.1.65Annotated reactions database
SPD / RIKEN22/22H06Orfeome Localization Data
UniProtKB/SwissProtO14333Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
ModBaseO14333Database of comparative protein structure models
STRINGO14333Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595799phosphatidylserine decarboxylase Psd1
RefSeq mRNANM_001021700972h- phosphatidylserine decarboxylase Psd1 (psd1), mRNA
European Nucleotide ArchiveCAB16910.2ENA Protein Mapping
MetaCycPWY-5669Phosphatidylethanolamine biosynthesis I
KEGG_Enzyme00564+4.1.1.65Glycerophospholipid metabolism
UniParcUPI000006C8C3UniProt Archive
UniPathwayUPA00558Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2

Literature for psd1

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015