psd1 (SPBC16E9.18)

Gene Standard Namepsd1 Characterisation Statuspublished
Systematic IDSPBC16E9.18 Feature Typeprotein coding
SynonymsSPBC1E8.01 Name Description
Productphosphatidylserine decarboxylase Psd1 Product Size437aa, 49.13 kDa
Genomic Location Chromosome II, 1955636-1957371 (1736nt); CDS:1955709-1957022 (1314nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
phosphatidylserine decarboxylase activity3
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
GO Cellular Component
Term NameCount
mitochondrial inner membrane164
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
normal growth on glucose carbon sourcepsd1Δ225
viable vegetative cell populationpsd1Δ3815

Cell Phenotype

Term NameGenotypesCount
normal vegetative cell morphologypsd1Δ551
viable vegetative cell with normal cell morphologypsd1Δ3095

Multi-allele phenotypes

Population Phenotype

Term NameGenotypes
growth auxotrophic for ethanolaminepsd3Δ, psd1Δ, psd2Δ
inviable vegetative cell populationpsd3Δ, psd1Δ, psd2Δ
viable vegetative cell populationpsd3Δ, psd1Δ, psd2Δ
psd1Δ, psd2Δ
psd1Δ, psd3Δ

Cell Phenotype

Term NameGenotypes
abnormal actomyosin contractile ring assemblypsd3Δ, psd1Δ
abnormal cell wall organization during vegetative growthpsd3Δ, psd1Δ
abnormal vegetative cell morphologypsd3Δ, psd1Δ, psd2Δ
decreased cellular phosphatidylethanolamine levelpsd3Δ, psd1Δ, psd2Δ
increased cellular phosphatidylserine levelpsd3Δ, psd1Δ, psd2Δ
mislocalized septum during vegetative growthpsd3Δ, psd1Δ, psd2Δ
misoriented septum during vegetative growthpsd3Δ, psd1Δ, psd2Δ
normal cellular phosphatidylcholine levelpsd3Δ, psd1Δ, psd2Δ
normal cellular phosphatidylinositol levelpsd3Δ, psd1Δ, psd2Δ
normal septationpsd3Δ, psd1Δ, psd2Δ
normal vegetative cell morphologypsd3Δ, psd1Δ
psd2Δ, psd1Δ
psd3Δ, psd1Δ, psd2Δ
pear-shaped vegetative cellpsd3Δ, psd1Δ, psd2Δ
spheroid vegetative cellpsd3Δ, psd1Δ, psd2Δ
viable elongated multiseptate vegetative cellpsd3Δ, psd1Δ, psd2Δ
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR1955636..1955708PMID:21511999
3' UTR1957023..1957371PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02666 Pfam IPR003817 Phosphatidylserine decarboxylase-related 131 430 3
TMhelix TMHMM 30 52 959
PTHR10067 HMMPANTHER IPR003817 Phosphatidylserine decarboxylase-related 39 433 3
TIGR00163 tigrfam IPR003817 Phosphatidylserine decarboxylase-related 118 430 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.42 Da
Charge 22.50
Codon Adpatation Index 0.38
Isoelectric point 9.95
Molecular weight 49.13 kDa
Number of residues 437
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3258during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
3113during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
851.73during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
3112during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.7during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
0.66during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3090
conserved in fungi4604
conserved in eukaryotes4514
conserved in bacteria1000
conserved in metazoa3421
conserved in vertebrates3396

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPBC16E9.18 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC16E9.18 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC16E9.18 BioGRID Interaction Datasets
Expression Viewer SPBC16E9.18 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC16E9.18 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC16E9.18 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC16E9.18 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC16E9.18 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC16E9.18 Transcriptome Viewer (Bähler Lab)
GEO SPBC16E9.18 GEO profiles
PInt SPBC16E9.18 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC16E9.18 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC16E9.18 Fission yeast phenotypic data & analysis
Cyclebase SPBC16E9.18.1 Cell Cycle Data
SPD / RIKEN22/22H06Orfeome Localization Data
IntEnz4.1.1.65Integrated relational Enzyme database
Rhea4.1.1.65Annotated reactions database
UniProtKB/SwissProtO14333Phosphatidylserine decarboxylase proenzyme 1, mitochondrial Phosphatidylserine decarboxylase 1 beta chain Phosphatidylserine decarboxylase 1 alpha chain
ModBaseO14333Database of comparative protein structure models
STRINGO14333Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595799phosphatidylserine decarboxylase Psd1
RefSeq mRNANM_001021700972h- phosphatidylserine decarboxylase Psd1 (psd1), mRNA
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveCAB16910ENA Protein Mapping
European Nucleotide ArchiveCAB16910.2ENA Protein Mapping
MetaCycPWY-5669Phosphatidylethanolamine biosynthesis I
KEGG00564+ metabolism
UniParcUPI000006C8C3UniProt Archive

Literature for psd1

Search: Europe PMC or PubMed

Release Version: PomBase:28_55 - 09 Sep 2015