SPBC1718.04


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPBC1718.04 Feature Typeprotein coding
Synonyms Name Description
Productglycerol-3-phosphate O-acyltransferase (predicted) Product Size675aa, 76.63 kDa
Genomic Location Chromosome II, 3475561-3478365 (2805nt); CDS:3475916-3477995 (2080nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0004366glycerol-3-phosphate O-acyltransferase activityISOSGD:S000000107GO_REF:00000241
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0008654phospholipid biosynthetic processISOSGD:S000000107GO_REF:000002469
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005783endoplasmic reticulumIDAPMID:16823372594
ISOSGD:S000000107GO_REF:0000024
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371017
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopySPBC1718.04ΔNullPECO:0000005, PECO:0000137PMID:236978061315
MicroscopySPBC1718.04ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000311inviable after spore germination with normal, unseptated germ tube morphologyMicroscopySPBC1718.04ΔNullPECO:0000005, PECO:0000137PMID:23697806237
FYPO:0002151inviable spore457
penetrance FYPO_EXT:0000001MicroscopySPBC1718.04ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
134755613475961
234760143478365

UTRs

Region Coordinates Reference
three_prime_UTR3477996..3478365PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01553 Pfam IPR002123 Phospholipid/glycerol acyltransferase 25 247 4
SM00563 SMART IPR002123 Phospholipid/glycerol acyltransferase 40 250 4
TMhelix TMHMM 5 22 959
TMhelix TMHMM 480 502 959
TMhelix TMHMM 451 473 959
TMhelix TMHMM 397 419 959
PTHR31605:SF0 HMMPANTHER 1 672 1
PTHR31605 HMMPANTHER 1 672 1
0039877 SuperFamily 191 294 4
0039877 SuperFamily 10 99 4

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 113.52 Da
Charge 25.50
Isoelectric point 9.49
Molecular weight 76.63 kDa
Number of residues 675
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
25200during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
27476during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
23604during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
1980.73during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
27135during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
24627during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
3.1during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
0.71during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4569
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPBC1718.04 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1718.04 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC1718.04 BioGRID Interaction Datasets
Expression Viewer SPBC1718.04 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC1718.04 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC1718.04 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC1718.04 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC1718.04 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC1718.04 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC1718.04 Cell Cycle Data
GEO SPBC1718.04 GEO profiles
PInt SPBC1718.04 Protein-Protein Interaction Predictor (Bähler Lab)
IntEnz2.3.1.15Integrated relational Enzyme database
Rhea2.3.1.15Annotated reactions database
EntrezGene2540110glycerol-3-phosphate O-acyltransferase (predicted)
WikiGene2540110glycerol-3-phosphate O-acyltransferase (predicted)
SPD / RIKEN46/46E05Orfeome Localization Data
UniProtKB/SwissProtQ9P7P0Uncharacterized acyltransferase C1718.04
ModBaseQ9P7P0Database of comparative protein structure models
STRINGQ9P7P0Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596450glycerol-3-phosphate O-acyltransferase (predicted)
RefSeq mRNANM_001022369972h- glycerol-3-phosphate O-acyltransferase (predicted) (SPBC1718.04), mRNA
European Nucleotide ArchiveCAB75994ENA Protein Mapping
European Nucleotide ArchiveCAB75994.1ENA Protein Mapping
UniParcUPI000006B46DUniProt Archive

Literature for SPBC1718.04

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014