sct1 (SPBC1718.04)

Gene Standard Namesct1 Characterisation Statusbiological role inferred
Systematic IDSPBC1718.04 Feature Typeprotein coding
Synonyms Name Description
Productglycerol-3-phosphate O-acyltransferase Sct1/Gpt1 (predicted) Product Size675aa, 76.63 kDa
Genomic Location Chromosome II, 3475561-3478365 (2805nt); CDS:3475916-3477995 (2080nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
glycerol-3-phosphate O-acyltransferase activity1
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
phospholipid biosynthetic process75
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
endoplasmic reticulum602
Annotation ExtensionEvidenceWith/FromReference
integral component of membrane969
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationsct1Δ1468

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination with normal, unseptated germ tube morphologysct1Δ237
inviable sporesct1Δ476
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3475561..3475961, 3476014..3478365
5' UTR3475561..3475915AU006920
CDS3475916..3475961, 3476014..3477995
3' UTR3477996..3478365PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01553 Pfam IPR002123 Phospholipid/glycerol acyltransferase 26 238 4
SM00563 SMART IPR002123 Phospholipid/glycerol acyltransferase 40 250 4
TMhelix TMHMM 451 473 950
TMhelix TMHMM 480 502 950
TMhelix TMHMM 397 419 950
TMhelix TMHMM 5 22 950
PTHR31605:SF0 HMMPANTHER 1 674 1
PTHR31605 HMMPANTHER 1 674 1
0039877 SuperFamily 191 294 4
0039877 SuperFamily 10 99 4

View domain organization at Pfam

Term IDTerm NameReferenceCount

Protein Properties

Ave. residue weight 113.52 Da
Charge 25.50
Codon Adaptation Index 0.42
Isoelectric point 9.49
Molecular weight 76.63 kDa
Number of residues 675

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS669, S674 2293
Annotation ExtensionEvidenceResidueReference
IDA S674 PMID:25720772
IDA S669 PMID:25720772
O-phosphorylated residueS667,S669, S667,S669,S674, S667,S674, S669,S674 2461
Annotation ExtensionEvidenceResidueReference
IDA S667,S669 PMID:25720772
IDA S669,S674 PMID:25720772
IDA S667,S669,S674 PMID:25720772
IDA S667,S674 PMID:25720772
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for sct1 (SPBC1718.04)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
27135during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
24627during GO:0000084PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
27476during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
25200during GO:0000087PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
23604during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
1980.73during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3.1during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
0.71during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3087
conserved in fungi4608

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPBC1718.04 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1718.04 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC1718.04 BioGRID Interaction Datasets
Expression Viewer SPBC1718.04 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC1718.04 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC1718.04 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC1718.04 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC1718.04 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC1718.04 Transcriptome Viewer (Bähler Lab)
GEO SPBC1718.04 GEO profiles
PInt SPBC1718.04 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC1718.04 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC1718.04 Fission yeast phenotypic data & analysis
Cyclebase SPBC1718.04.1 Cell Cycle Data
IntEnz2.3.1.15Integrated relational Enzyme database
Rhea2.3.1.15Annotated reactions database
SPD / RIKEN46/46E05Orfeome Localization Data
UniProtKB/SwissProtQ9P7P0Uncharacterized acyltransferase C1718.04
ModBaseQ9P7P0Database of comparative protein structure models
STRINGQ9P7P0Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596450glycerol-3-phosphate O-acyltransferase (predicted)
RefSeq mRNANM_001022369972h- glycerol-3-phosphate O-acyltransferase (predicted) (SPBC1718.04), mRNA
European Nucleotide ArchiveCAB75994.1ENA Protein Mapping
UniParcUPI000006B46DUniProt Archive

Literature for sct1

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017