rap1 (SPBC1778.02)

Synonyms ChromosomeII
Producttelomere binding protein Rap1 Gene Start3098295
Feature Typeprotein coding Gene End3100698
Name Description CDS Start3098366
Characterisation Statuspublished CDS End3100576

Ensembl Gene Location
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
130982953098461
230985083098879
330989633100698

Protein Feature Information

Protein Features

Ensembl protein image with mapped locations of structural domains
Feature ID Database Description Start End Score All Genes
PF09197 Pfam Rap1, DNA-binding 495 602 61.3 1
46689 Superfamily 121 175 38.8 24
PS50172 PROSITE BRCT domain 81 105 9.445 13

Protein Properties

Ave. residue weight 114.76 Da
Charge -6.00
Isoelectric point 6.07
Molecular weight 79.53 kDa
Number of residues 693
Sequence

Fission Yeast Phenotype

Term IDDescriptionSourceAll Genes
FYPO:0000124viableTemporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000124

Gene Ontology Annotations

Biological Process
GO IDTermEvidenceWith/FromSourceAll Genes
GO:0006366transcription from RNA polymerase II promoterISS SGD:S000005160GO_REF:0000024Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0006366
GO:0016233telomere cappingIC GO:0000782GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0016233
GO:0031848protection from non-homologous end joining at telomereIGI taz1Temporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0031848
GO:0031860telomeric 3' overhang formationIGI taz1Temporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0031860
GO:0045141meiotic telomere clusteringIMPTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0045141

Cellular Component
GO IDTermEvidenceWith/FromSourceAll Genes
GO:0000781chromosome, telomeric regionIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0000781
GO:0005634nucleusIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005634
IDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year reference
GO:0005724nuclear telomeric heterochromatinISS SGD:S000005160GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005724
GO:0070187telosomeISS SGD:S000005160GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0070187

Molecular Function
GO IDTermEvidenceWith/FromSourceAll Genes
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingIC GO:0000978GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0000978
( SGD:S000005160)ISS SGD:S000005160GO_REF:0000024
GO:0005515protein bindingIPI taz1Temporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005515
( poz1)IPI poz1Temporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year reference
( bqt4)IPI bqt4Temporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year reference

Warning

DescriptionSourceAll Genes
gene structure updatedTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000070

Protein Family

DescriptionSourceAll Genes
BRCT domainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000443
Myb familyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001260

Species Distribution

DescriptionSourceAll Genes
conserved in FungiTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000057
conserved in Eukaryotes onlyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000096
conserved in VertebratesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000095
conserved in EukaryotesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000058
predominantly uniformly single copy (one to one)Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000104
conserved in MetazoaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000094

Manually Curated Orthologs

SpeciesGeneDescription

Interactions

Genetic Interactions from BioGRID

Gene Feature Evidence Source
epe1Jmjc domain chromatin associated protein Epe1 Negative Genetic
SPAC4F10.04protein phosphatase type 2A, intrinsic regulator (predicted) Negative Genetic
elp3elongator complex, histone acetyltransferase subunit Elp3 (predicted) Negative Genetic
swc5Swr1 complex subunit Swc5 Negative Genetic
SPAC637.06alpha-1,2-galactosyltransferase (predicted) Negative Genetic
vps71Swr1 complex subunit Vps71 Negative Genetic
hrp3ATP-dependent DNA helicase Hrp3 Negative Genetic
top2DNA topoisomerase II Synthetic Rescue
elp2elongator complex subunit Elp2 (predicted) Negative Genetic
pmc5mediator complex subunit Pmc5 Negative Genetic
ash2Ash2-trithorax family protein Negative Genetic
rif1telomere length regulator protein Rif1 Synthetic Rescue
Phenotypic Enhancement
set1histone lysine methyltransferase Set1 Negative Genetic
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative Genetic
mst2histone acetyltransferase Mst2 Negative Genetic
hip1hira protein, histone chaperone Hip1 Negative Genetic
SPBC16C6.05mitochondrial translation initiation factor (predicted) Negative Genetic
SPBC1861.07elongin C (predicted) Negative Genetic
SPBC31F10.12RNA-binding protein Tma20 (predicted) Negative Genetic
rhp14XP-A family homolog Rhp14 Negative Genetic
arp42SWI/SNF and RSC complex subunit Arp42 Negative Genetic
mrc1mediator of replication checkpoint 1 Negative Genetic
lig4DNA ligase Lig4 Phenotypic Suppression
SPBC2F12.03cEST1 family protein (predicted) Negative Genetic
SPAC631.02bromodomain protein (predicted) Negative Genetic
SPCC550.03cSki complex RNA helicase Ski2 (predicted) Negative Genetic
pst2Clr6 histone deacetylase complex subunit Pst2 Phenotypic Enhancement
cds1replication checkpoint kinase Cds1 Negative Genetic
pht1histone H2A variant H2A.Z, Pht1 Negative Genetic
arp8actin-like protein Arp8 Negative Genetic
pcf3CAF assembly factor (CAF-1) complex subunit C, Pcf3 Negative Genetic
rhp51RecA family recombinase Rhp51 Negative Genetic
rad26ATRIP, ATR checkpoint kinase regulatory subunit Rad26 Negative Genetic
mad1mitotic spindle checkpoint protein Mad1 Negative Genetic
taz1human TRF ortholog Taz1 Phenotypic Enhancement
Synthetic Growth Defect
ubp3ubiquitin C-terminal hydrolase Ubp3 Negative Genetic
iki1elongator complex subunit Iki1 (predicted) Negative Genetic
rhp57RecA family ATPase Rhp57 Synthetic Growth Defect
Negative Genetic
SPAC23A1.19cRecQ type DNA helicase Hrq1 (predicted) Negative Genetic
SPBC2F12.12chuman c19orf29 ortholog Negative Genetic
msh6MutS protein homolog Negative Genetic
SPBP8B7.31acid phosphatase (predicted) Negative Genetic
tas3RITS complex subunit 3 Negative Genetic

Physical Interactions from BioGRID

Gene Feature Evidence Source
bqt2bouquet formation protein Bqt2 Affinity Capture-Western
taz1human TRF ortholog Taz1 Co-crystal Structure
Reconstituted Complex
Two-hybrid
Co-localization
Two-hybrid
Two-hybrid
Co-localization
Co-localization
Two-hybrid

External References

Database Identifier Description
NBRP SPBC1778.02 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1778.02 Retrieval of eukaryotic orthologs
BioGrid SPBC1778.02 BioGRID Interaction Datasets
Bähler Lab SPBC1778.02 Cell Cycle Expression Profile
Bähler Lab SPBC1778.02 Meiosis/Sporulation Expression Profies
Bähler Lab SPBC1778.02 Pheromone response/mating expression profiles
Bähler Lab SPBC1778.02 Environmental stress expression profiles
Bähler Lab SPBC1778.02 Bähler Lab Transcriptome Viewer
Cyclebase SPBC1778.02 Cell Cycle Data
Entrez Gene SPBC1778.02 Link to Entrez Gene
SPD / RIKEN26/26G09Orfeome Localization Data
UniProtKB/SwissProtQ96TL7DNA-binding protein rap1
ArrayExpressQ96TL7Link to ArrayExpress
RefSeq PeptideNP_596285telomere binding protein Rap1
RefSeq mRNANM_001022207972h- telomere binding protein Rap1 (rap1), mRNA
European Nucleotide ArchiveAB027870ENA EMBL mapping
European Nucleotide ArchiveAB027963ENA EMBL mapping
European Nucleotide ArchiveAB061738ENA EMBL mapping
European Nucleotide ArchiveAY034032ENA EMBL mapping
European Nucleotide ArchiveCU329671ENA EMBL mapping
ePDB2L3NLink to the European PDB
PDBsum2L3NLink to PDBsum
European Nucleotide ArchiveAAK57740ENA Protein Mapping
European Nucleotide ArchiveBAA87174ENA Protein Mapping
European Nucleotide ArchiveBAA87267ENA Protein Mapping
European Nucleotide ArchiveBAB70735ENA Protein Mapping
European Nucleotide ArchiveCAC39280ENA Protein Mapping
UniParcUPI0000133112UniProt Archive

Literature for rap1

Search: UK PMC or PubMed