SPBC1778.09

Gene Standard NameUnassigned ChromosomeII
Systematic IDSPBC1778.09 Gene Start3112395
Synonyms Gene End3114397
ProductGTPase activating protein (predicted) Gene Length2003
Feature Typeprotein coding CDS Start3112724
Name Description CDS End3113968
Characterisation Statusbiological_role_inferred CDS Length1245

Ensembl Gene Location
  1. SPBC1778.05c
  2. fim1
  3. SPBC1778.07
  4. arc3
  5. SPBC1778.09
  6. ppk21
  7. pre3
  8. SPBC4C3.09
  9. SPNCRNA.1580
  10. mug136
  11. prl23
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPBC1778.09delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005097Rab GTPase activator activityISMPFAM:PF00566GO_REF:0000001
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0016192vesicle-mediated transportNASGO_REF:0000051
GO:0032313regulation of Rab GTPase activityISMPFAM:PF00566GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
131123953114397

References

Region Start End Reference
three_prime_UTR31139693114397PMID:21511999
three_prime_UTR31139693114397PMID:21511999
five_prime_UTR31123953112723PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00566 IPR000195 Pfam Rab-GTPase-TBC domain 169 361 13
SM00164 IPR000195 SMART Rab-GTPase-TBC domain 155 373 13
PS50086 IPR000195 Prosite Profiles Rab-GTPase-TBC domain 158 343 13
G3DSA:1.10.8.270 Gene3D 151 269 12
SSF47923 IPR000195 SuperFamily 146 297 13
SSF47923 IPR000195 SuperFamily 302 401 13
PTHR22957:SF46 hmmpanther 92 397 1
PTHR22957 hmmpanther 92 397 12

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.22 Da
Charge 10.00
Isoelectric point 8.97
Molecular weight 47.70 kDa
Number of residues 414
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide494.38PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide3.3PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.71PMID:23101633
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
mid2medial ring protein Mid2 Negative GeneticPMID:22681890
iwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:22681890
SPCC162.11curidine kinase/uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
tma23ribosome biogenesis protein Tma23 (predicted) Negative GeneticPMID:22681890
sty1MAP kinase Sty1 Negative GeneticPMID:22681890
fft3fun thirty related protein Fft3 Negative GeneticPMID:22681890
mug154conserved fungal protein Negative GeneticPMID:22681890
dim1U4/U6 x U5 tri-snRNP complex subunit Dim1 Negative GeneticPMID:22681890
trm10tRNA m(1)G methyltransferase Trm10 (predicted) Negative GeneticPMID:22681890
sts5RNB-like protein Positive GeneticPMID:22681890
ask1DASH complex subunit Ask1 Positive GeneticPMID:22681890
pby1tubulin-tyrosine ligase Pby1 (predicted) Negative GeneticPMID:22681890
dad2DASH complex subunit Dad2 Positive GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
rad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
ura5orotate phosphoribosyltransferase Ura5 Negative GeneticPMID:22681890
klp3kinesin-like protein Klp3 Negative GeneticPMID:22681890
mug67PPPDE peptidase family (predicted) Negative GeneticPMID:22681890
cdt2WD repeat protein Cdt2 Negative GeneticPMID:22681890
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
hri1eIF2 alpha kinase Hri1 Negative GeneticPMID:22681890
spn1septin Spn1 Negative GeneticPMID:22681890
caf16CCR4-Not complex subunit Caf16 (predicted) Negative GeneticPMID:22681890
cdk11serine/threonine protein kinase cdk11 Negative GeneticPMID:22681890
dmc1RecA family ATPase Dmc1 Negative GeneticPMID:22681890
SPAC821.05translation initiation factor eIF3h (p40) Positive GeneticPMID:22681890
rxt2histone deacetylase complex subunit Rxt2 Negative GeneticPMID:22681890
SPAC144.05ATP-dependent DNA helicase (predicted) Negative GeneticPMID:22681890
SPAC12B10.13proteasome-dependent catabolite inactivation protein, ubiquitin ligase complex subunit (predicted) Negative GeneticPMID:22681890
res2MBF transcription factor complex subunit Res2 Positive GeneticPMID:22681890
rad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:22681890
swd3WD repeat protein Swd3 Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPBC1778.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1778.09 Retrieval of eukaryotic orthologs
BioGrid SPBC1778.09 BioGRID Interaction Datasets
Bähler Lab SPBC1778.09 Cell Cycle Expression Profile
Bähler Lab SPBC1778.09 Meiosis/Sporulation Expression Profies
Bähler Lab SPBC1778.09 Pheromone response/mating expression profiles
Bähler Lab SPBC1778.09 Environmental stress expression profiles
Bähler Lab SPBC1778.09 Bähler Lab Transcriptome Viewer
Cyclebase SPBC1778.09 Cell Cycle Data
PInt SPBC1778.09 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC1778.09 Entrez Gene
EntrezGene2539715GTPase activating protein (predicted)
WikiGene2539715GTPase activating protein (predicted)
SPD / RIKEN19/19H05Orfeome Localization Data
UniProtKB/SwissProtQ9Y7J5TBC domain-containing protein C1778.09
ModBaseQ9Y7J5Database of comparative protein structure models
Pfam Protein DomainsQ9Y7J5Pfam Domain Arrangement
RefSeq PeptideNP_596292GTPase activating protein (predicted)
RefSeq mRNANM_001022214972h- GTPase activating protein (predicted) (SPBC1778.09), mRNA
European Nucleotide ArchiveCAB39804ENA Protein Mapping
UniParcUPI000006B0BDUniProt Archive

Literature for SPBC1778.09
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013