rga5 (SPBC17F3.01c)

Gene Standard Namerga5 ChromosomeII
Systematic IDSPBC17F3.01c Gene Start2486559
SynonymsSPBC557.01 Gene End2488209
ProductRho-type GTPase activating protein Rga5 Gene Length1651
Feature Typeprotein coding CDS Start2486807
Name Description CDS End2487892
Characterisation Statuspublished CDS Length1086

Ensembl Gene Location
  1. ste20
  2. SPBC12C2.01c
  3. nak1
  4. SPNCRNA.1519
  5. prl8
  6. prl9
  7. rga5
  8. SPBC557.02c
  9. SPNCRNA.1520
  10. pim1
  11. SPNCRNA.1521
  12. SPNCRNA.398
  13. ppk29
  14. pnc1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000223elongated multiseptate cellsrga5delta (deletion)deletionPECO:0000004PMID:12519200
FYPO:0002060viable vegetative cell populationMicroscopyrga5delta (deletion)deletionPMID:20473289
no_name (unrecorded)unrecordedPMID:12519200
rga5delta (deletion)deletionPMID:11737264
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005100Rho GTPase activator activityIDAPMID:12519200
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0008360regulation of cell shapeIMPPMID:12519200
GO:0032321positive regulation of Rho GTPase activityIDAPMID:12519200
GO:0090334regulation of cell wall (1->3)-beta-D-glucan biosynthetic processIMPPMID:12519200
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0016020membraneIEASL-0162GO_REF:0000039
GO:0031097medial cortexIDAPMID:12519200
GO:0051286cell tipIDAPMID:12519200
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
124865592488209

References

Region Start End Reference
three_prime_UTR24878932488209PMID:21511999
five_prime_UTR24865592486806PMID:21511999
three_prime_UTR24878932488209PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00620 IPR000198 Pfam Rho GTPase-activating protein domain 68 220 10
SM00324 IPR000198 SMART Rho GTPase-activating protein domain 65 253 10
PS50238 IPR000198 Prosite Profiles Rho GTPase-activating protein domain 52 245 10
G3DSA:1.10.555.10 IPR000198 Gene3D 66 246 10
SSF48350 IPR008936 SuperFamily 33 242 12
PTHR23176 hmmpanther 20 358 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 113.51 Da
Charge 22.50
Isoelectric point 10.59
Molecular weight 40.98 kDa
Number of residues 361
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide3564.24PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide22182.25PMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1.8PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.86PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
rho1Rho family GTPase Rho1 Synthetic RescuePMID:12519200
par1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:22681890
pxl1paxillin-like protein Pxl1 Phenotypic EnhancementPMID:18256290
ccr4CCR4-Not complex subunit Ccr4 (predicted) Positive GeneticPMID:22681890
pck1protein kinase C (PKC)-like Pck1 Synthetic RescuePMID:12519200
SPAC3A11.13prefoldin subunit 6 (predicted) Positive GeneticPMID:22681890
mid1medial ring protein Mid1 Positive GeneticPMID:22681890
sts5RNB-like protein Positive GeneticPMID:22681890
ubp2ubiquitin C-terminal hydrolase Ubp2 Positive GeneticPMID:22681890
swd3WD repeat protein Swd3 Positive GeneticPMID:22681890
nup40nucleoporin Nup40 Negative GeneticPMID:22681890
dad1DASH complex subunit Dad1 Positive GeneticPMID:22681890
pom1DYRK family protein kinase Pom1 Negative GeneticPMID:22681890
fft3fun thirty related protein Fft3 Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPBC17F3.01c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC17F3.01c Retrieval of eukaryotic orthologs
BioGrid SPBC17F3.01c BioGRID Interaction Datasets
Bähler Lab SPBC17F3.01c Cell Cycle Expression Profile
Bähler Lab SPBC17F3.01c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC17F3.01c Pheromone response/mating expression profiles
Bähler Lab SPBC17F3.01c Environmental stress expression profiles
Bähler Lab SPBC17F3.01c Bähler Lab Transcriptome Viewer
Cyclebase SPBC17F3.01c Cell Cycle Data
PInt SPBC17F3.01c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC17F3.01c Entrez Gene
SPD / RIKEN16/16H09Orfeome Localization Data
EntrezGene2539707Rho-type GTPase activating protein Rga5
Uniprot_genenameRGA5
WikiGene2539707Rho-type GTPase activating protein Rga5
UniProtKB/SwissProtO74335Rho-GTPase-activating protein 5
ModBaseO74335Database of comparative protein structure models
Pfam Protein DomainsO74335Pfam Domain Arrangement
RefSeq PeptideNP_596024Rho-type GTPase activating protein Rga5
RefSeq mRNANM_001021932972h- Rho-type GTPase activating protein Rga5 (rga5), mRNA
European Nucleotide ArchiveAAY18722ENA Protein Mapping
European Nucleotide ArchiveCAA20323ENA Protein Mapping
UniParcUPI00001868E2UniProt Archive

Literature for rga5
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013