rps21 (SPBC18E5.06)

Gene Standard Namerps21 Characterisation Statuspublished
Systematic IDSPBC18E5.06 Feature Typeprotein coding
Synonyms Name Description
Product40S ribosomal protein S21 Product Size87aa, 9.62 kDa
Genomic Location Chromosome II, 2083801-2084323 (523nt); CDS:2083868-2084184 (317nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
protein binding863
Annotation ExtensionEvidenceWith/FromReference
structural constituent of ribosome257
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation468
Annotation ExtensionEvidenceWith/FromReference
cytoplasmic translational elongation194
Annotation ExtensionEvidenceWith/FromReference
ribosomal small subunit biogenesis55
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
cytosolic small ribosomal subunit65
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationrps21Δ1444

Cell Phenotype

Term NameGenotypesCount
abnormal mitotic cell cyclerps21Δ834
inviable after spore germination, multiple cell divisions, cell cycle arrest in mitotic interphase, elongated cellsrps21Δ88
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2083801..2083917, 2083971..2084323
5' UTR2083801..2083867PMID:21511999
CDS2083868..2083917, 2083971..2084184
3' UTR2084185..2084323PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01249 Pfam IPR001931 Ribosomal protein S21e 1 79 1
PS00996 Prosite Patterns IPR018279 Ribosomal protein S21e, conserved site 11 19 1
PTHR10442 HMMPANTHER IPR001931 Ribosomal protein S21e 2 87 1
PD006584 blastprodom IPR001931 Ribosomal protein S21e 24 87 1
PIRSF002148 PIRSF IPR001931 Ribosomal protein S21e 1 87 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.54 Da
Charge -1.50
Isoelectric point 5.05
Molecular weight 9.62 kDa
Number of residues 87

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS18 1674
Annotation ExtensionEvidenceResidueReference
experimental evidence S18 PMID:24763107
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
439908during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
427540during GO:0000084PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
424973during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
420029during GO:0000087PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
414002during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
122953.94during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
72867.33during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
160during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
15during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
conserved in fungi4604
conserved in eukaryotes4514
conserved in metazoa3421
conserved in vertebrates3396
conserved in eukaryotes only2503

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Load gene that interact physically with SPBC18E5.06 into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity capturesrps00240S ribosomal protein S0B Affinity Capture-WesternPMID:14623272
affinity capturesrps00140S ribosomal protein S0A (p40) Affinity Capture-WesternPMID:14623272
binds DNA-binding domain construct withrps00140S ribosomal protein S0A (p40) Two-hybridPMID:14623272
affinity captured byfar8SIP/FAR complex striatin subunit, Far8/Csc3 Affinity Capture-MSPMID:22119525
External References
Database Identifier Description
NBRP SPBC18E5.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC18E5.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC18E5.06 BioGRID Interaction Datasets
Expression Viewer SPBC18E5.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC18E5.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC18E5.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC18E5.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC18E5.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC18E5.06 Transcriptome Viewer (Bähler Lab)
GEO SPBC18E5.06 GEO profiles
PInt SPBC18E5.06 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC18E5.06 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC18E5.06 Fission yeast phenotypic data & analysis
Cyclebase SPBC18E5.06.1 Cell Cycle Data
SPD / RIKEN31/31C08Orfeome Localization Data
UniProtKB/SwissProtP0576440S ribosomal protein S21
ModBaseP05764Database of comparative protein structure models
STRINGP05764Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59585240S ribosomal protein S21
RefSeq mRNANM_001021756972h- 40S ribosomal protein S21 (rps21), mRNA
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveCAA22666ENA Protein Mapping
European Nucleotide ArchiveCAA22666.1ENA Protein Mapping
UniParcUPI0000134E89UniProt Archive

Literature for rps21

Search: Europe PMC or PubMed

Release Version: PomBase:29_56 - 12 Nov 2015