rps21 (SPBC18E5.06)


Gene Standard Namerps21 Characterisation Statuspublished
Systematic IDSPBC18E5.06 Feature Typeprotein coding
Synonyms Name Description
Product40S ribosomal protein S21 Product Size87aa, 9.62 kDa
Genomic Location Chromosome II, 2083801-2084323 (523nt); CDS:2083868-2084184 (317nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
protein binding831
Annotation ExtensionEvidenceWith/FromReference
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translational elongation194
Annotation ExtensionEvidenceWith/FromReference
ribosomal small subunit biogenesis54
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2315
Annotation ExtensionEvidenceWith/FromReference
cytosolic small ribosomal subunit65
Annotation ExtensionEvidenceWith/FromReference
nucleus2740
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopynot recorded (unrecorded)PMID:146232721338
Microscopyrps21ΔNullPMID:20473289
Microscopyrps21ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000059abnormal mitotic cell cycleMicroscopyrps21ΔNullPECO:0000005, PECO:0000137PMID:23697806686
FYPO:0003529inviable after spore germination, multiple cell divisions, cell cycle arrest in mitotic interphase, elongated cells87
penetrance FYPO_EXT:0000001Microscopyrps21ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
120838012083917
220839712084323

UTRs

Region Coordinates Reference
five_prime_UTR2083801..2083867PMID:21511999
three_prime_UTR2084185..2084323PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01249 Pfam IPR001931 Ribosomal protein S21e 1 80 1
PS00996 Prosite Patterns IPR018279 Ribosomal protein S21e, conserved site 11 19 1
PTHR10442 HMMPANTHER IPR001931 Ribosomal protein S21e 2 87 1
PIRSF002148 PIRSF IPR001931 Ribosomal protein S21e 1 86 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.54 Da
Charge -1.50
Isoelectric point 5.05
Molecular weight 9.62 kDa
Number of residues 87
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineexperimental evidenceS18PMID:247631071670
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
439908during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
427540during GO:0000084PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
424973during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
420029during GO:0000087PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
122953.94during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
414002during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
72867.33during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
160during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
15during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in eukaryotes only2497
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
far8SIP/FAR complex striatin subunit, Far8/Csc3 Affinity Capture-MSPMID:22119525
rps00140S ribosomal protein S0A (p40) Two-hybridPMID:14623272
Affinity Capture-Western
rps00240S ribosomal protein S0B Affinity Capture-WesternPMID:14623272
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPBC18E5.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC18E5.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC18E5.06 BioGRID Interaction Datasets
Expression Viewer SPBC18E5.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC18E5.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC18E5.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC18E5.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC18E5.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC18E5.06 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC18E5.06 Cell Cycle Data
GEO SPBC18E5.06 GEO profiles
PInt SPBC18E5.06 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC18E5.06 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC18E5.06 Fission yeast phenotypic data & analysis
SPD / RIKEN31/31C08Orfeome Localization Data
UniProtKB/SwissProtP0576440S ribosomal protein S21
ModBaseP05764Database of comparative protein structure models
STRINGP05764Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59585240S ribosomal protein S21
RefSeq mRNANM_001021756972h- 40S ribosomal protein S21 (rps21), mRNA
European Nucleotide ArchiveCAA22666.1ENA Protein Mapping
UniParcUPI0000134E89UniProt Archive

Literature for rps21

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014