rps21 (SPBC18E5.06)

Gene Standard Namerps21 Characterisation Statuspublished
Systematic IDSPBC18E5.06 Feature Typeprotein coding
Synonyms Name Description
Product40S ribosomal protein S21 Product Size87aa, 9.62 kDa
Genomic Location Chromosome II, 2083801-2084323 (523nt); CDS:2083868-2084184 (317nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005515protein bindingIPIrps002PMID:14623272887
GO:0003735structural constituent of ribosomeIEAIPR001931GO_REF:0000002255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002182cytoplasmic translational elongationNASGO_REF:0000051193
GO:0042274ribosomal small subunit biogenesisIMPPMID:1462327252
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0022627cytosolic small ribosomal subunitTASPMID:1462327263
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationno_namePMID:146232721309
Microscopyrps21ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000059abnormal mitotic cell cycleMicroscopyrps21ΔNullPECO:0000005, PECO:0000137PMID:23697806564
FYPO:0002262inviable after spore germination, multiple cell divisions, elongated cellMicroscopyrps21ΔNullPECO:0000005, PECO:0000137PMID:2369780687
penetrance FYPO_EXT:0000001
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Start End Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01249 Pfam IPR001931 Ribosomal protein S21e 1 80 1
PS00996 Prosite Patterns IPR018279 Ribosomal protein S21e 11 19 1
PTHR10442 HMMPANTHER IPR001931 Ribosomal protein S21e 2 87 1
PD006584 blastprodom IPR001931 Ribosomal protein S21e 24 87 1
PIRSF002148 PIRSF IPR001931 Ribosomal protein S21e 1 86 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.54 Da
Charge -1.50
Isoelectric point 5.05
Molecular weight 9.62 kDa
Number of residues 87
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
122953.94during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
72867.33during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
15during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
160during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in eukaryotes only2485

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
rps00240S ribosomal protein S0B Affinity Capture-WesternPMID:14623272
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
rps00140S ribosomal protein S0A (p40) Two-hybridPMID:14623272
Affinity Capture-Western
far8SIP/FAR complex striatin subunit, Far8/Csc3 Affinity Capture-MSPMID:22119525
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
External References
Database Identifier Description
NBRP SPBC18E5.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC18E5.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC18E5.06 BioGRID Interaction Datasets
Expression Viewer SPBC18E5.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC18E5.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC18E5.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC18E5.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC18E5.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC18E5.06 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC18E5.06 Cell Cycle Data
GEO SPBC18E5.06 GEO profiles
PInt SPBC18E5.06 Protein-Protein Interaction Predictor (Bähler Lab)
EntrezGene254080640S ribosomal protein S21
WikiGene254080640S ribosomal protein S21
SPD / RIKEN31/31C08Orfeome Localization Data
UniProtKB/SwissProtP0576440S ribosomal protein S21
ModBaseP05764Database of comparative protein structure models
StringP05764Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59585240S ribosomal protein S21
RefSeq mRNANM_001021756972h- 40S ribosomal protein S21 (rps21), mRNA
European Nucleotide ArchiveCAA22666ENA Protein Mapping
UniParcUPI0000134E89UniProt Archive

Literature for rps21

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014