ubp4 (SPBC18H10.08c)

Synonyms ChromosomeII
Productubiquitin C-terminal hydrolase Ubp4 Gene Start1786542
Feature Typeprotein coding Gene End1783861
Name Description CDS Start1786248
Characterisation Statuspublished CDS End1784219

Ensembl Gene Location
SPNCRNA.1463 meu11 SPBC18H10.05 swd2 SPBC18H10.07 > ubp4 < SPBC18H10.09 saf4 ppr2 rpl701 snoR39b rps1402
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
117865421786475
217864341786141
317860801785937
417857481783861

Protein Feature Information
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Protein Features

Ensembl protein image with mapped locations of structural domains
Feature ID Database Description Start End Score All Genes
PF00443 Pfam Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 225 570 214.6 16
54001 Superfamily 223 573 282.1 29
PS50235 PROSITE Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 227 574 28.928 16
PS00972 scanprosite Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 228 243 12
PS00973 scanprosite Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2 514 531 14


Protein Modifications

Term IDDescriptionSourceAll Genes
MOD:00696phosphorylated residueTemporary processing gif - replaced by AJAX with count of genes annotated with the term MOD:00696

Protein Properties

Ave. residue weight 114.25 Da
Charge 14.00
Isoelectric point 8.16
Molecular weight 67.75 kDa
Number of residues 593
Sequence
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Fission Yeast Phenotype

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Term IDDescriptionSourceAll Genes
FYPO:0000124viableTemporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000124

Gene Ontology Annotations

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Biological Process
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0016579protein deubiquitinationIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0016579

Cellular Component
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0005737cytoplasmIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005737
GO:0005768endosomeIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005768
GO:0030133transport vesicleIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0030133
GO:0032153cell division siteIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0032153

Molecular Function
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0004221ubiquitin thiolesterase activityIEAGO_REF:0000002Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0004221
GO:0004843ubiquitin-specific protease activityIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0004843
GO:0005515protein bindingIPI sfp47Temporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005515

Warning

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DescriptionSourceAll Genes
gene structure updatedTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000070

Species Distribution

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DescriptionSourceAll Genes
conserved in MetazoaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000094
conserved in FungiTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000057
conserved in EukaryotesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000058
conserved in VertebratesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000095
conserved in Eukaryotes onlyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000096

Manually Curated Orthologs

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SpeciesGeneDescription

Interactions

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Genetic Interactions from BioGRID

Gene Feature Evidence Source
sum2G2/M transition checkpoint protein Sum2 Negative Genetic
SPBC4B4.04translation initiation factor eIF2A (predicted) Negative Genetic
vph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Negative Genetic
sgf29SAGA complex subunit Sgf29 Negative Genetic
ryh1GTPase Ryh1 Negative Genetic
dsc3conserved fungal protein Negative Genetic
pmc5mediator complex subunit Pmc5 Negative Genetic
med20mediator complex subunit Med20 Negative Genetic
set1histone lysine methyltransferase Set1 Negative Genetic
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative Genetic
swd1Set1C complex subunit Swd1 Negative Genetic
ccr4CCR4-Not complex subunit Ccr4 (predicted) Positive Genetic
ubp2ubiquitin C-terminal hydrolase Ubp2 Negative Genetic
spf1Set1C PHD Finger protein Spf1 Negative Genetic
arp42SWI/SNF and RSC complex subunit Arp42 Negative Genetic
hip4histone promoter control protein Hip4 Negative Genetic
vps24ESCRT III complex subunit Vps24 Phenotypic Enhancement

Physical Interactions from BioGRID

Gene Feature Evidence Source
sfp47Ubp4 interactor Sfp47 Affinity Capture-MS
Affinity Capture-Western

External References

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Database Identifier Description
NBRP SPBC18H10.08c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC18H10.08c Retrieval of eukaryotic orthologs
BioGrid SPBC18H10.08c BioGRID Interaction Datasets
Bähler Lab SPBC18H10.08c Cell Cycle Expression Profile
Bähler Lab SPBC18H10.08c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC18H10.08c Pheromone response/mating expression profiles
Bähler Lab SPBC18H10.08c Environmental stress expression profiles
Bähler Lab SPBC18H10.08c Bähler Lab Transcriptome Viewer
Cyclebase SPBC18H10.08c Cell Cycle Data
Entrez Gene SPBC18H10.08c Link to Entrez Gene
SPD / RIKEN44/44C04Orfeome Localization Data
UniProtKB/SwissProtO60139Probable ubiquitin carboxyl-terminal hydrolase 4
ArrayExpressO60139Link to ArrayExpress
RefSeq PeptideNP_595732ubiquitin C-terminal hydrolase Ubp4
RefSeq mRNANM_001021630972h- ubiquitin C-terminal hydrolase Ubp4 (ubp4), mRNA
European Nucleotide ArchiveCU329671ENA EMBL mapping
MEROPSC19.A42
European Nucleotide ArchiveCAA18405ENA Protein Mapping
UniParcUPI000228F499UniProt Archive

Literature for ubp4

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Search: UK PMC or PubMed