fba1 (SPBC19C2.07)

Gene Standard Namefba1 ChromosomeII
Systematic IDSPBC19C2.07 Gene Start1688336
Synonyms Gene End1689599
Productfructose-bisphosphate aldolase Fba1 Gene Length1264
Feature Typeprotein coding CDS Start1688367
Name Description CDS End1689443
Characterisation Statuspublished CDS Length1077

Ensembl Gene Location
  1. ran1
  2. mug124
  3. SPNCRNA.1452
  4. SPNCRNA.1453
  5. fba1
  6. prp38
  7. sre1
  8. SPBC19C2.10
  9. SPNCRNA.1454
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002061inviable vegetative cell populationMicroscopyfba1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0004332fructose-bisphosphate aldolase activityISSUniProtKB:P14540GO_REF:0000001
GO:0008270zinc ion bindingIEAIPR000771GO_REF:0000002
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006096glycolysisISSUniProtKB:P14540GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005737cytoplasmISSUniProtKB:P14540GO_REF:0000001
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
116883361689599
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF01116 IPR000771 Pfam Ketose-bisphosphate aldolase, class-II 14 356 1
PS00602 IPR000771 Prosite Patterns Ketose-bisphosphate aldolase, class-II 98 110 1
PS00806 IPR000771 Prosite Patterns Ketose-bisphosphate aldolase, class-II 170 181 1
G3DSA:3.20.20.70 IPR013785 Gene3D 10 356 35
SSF51569 SuperFamily 1 357 9
PIRSF001359 IPR000771 PIRSF Ketose-bisphosphate aldolase, class-II 11 358 1
PTHR30559:SF0 hmmpanther 1 358 1
PTHR30559 hmmpanther 1 358 1
TIGR01520 IPR006411 tigrfam Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype 3 357 1
TIGR00167 IPR000771 tigrfam Ketose-bisphosphate aldolase, class-II 13 357 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744

Protein Properties

Ave. residue weight 110.53 Da
Charge -1.50
Isoelectric point 6.32
Molecular weight 39.57 kDa
Number of residues 358
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide292133.4PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1025542.06PMID:23101633
RNA levelNorthern assay evidencesingle-celled organism vegetative growth phasepresentPMID:8286404
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide66PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide520PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in bacteria
Manually curated orthologous groups
SpeciesGeneDescription

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Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
air1zinc knuckle TRAMP complex subunit Air1 Affinity Capture-MSPMID:20403971
far8SIP/FAR complex striatin subunit, Far8/Csc3 Affinity Capture-MSPMID:22119525
zfs1CCCH tandem zinc finger protein, human Tristetraprolin homolog Zfs1, involved in mRNA catabolism Two-hybridPMID:19682301
sds23PP2A-type phosphatase inhibitor Sds23/Moc1 Two-hybridPMID:19682301
slm9hira protein Slm9 Affinity Capture-MSPMID:20976105
lrp1leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
paa1protein phosphatase regulatory subunit Paa1 Affinity Capture-MSPMID:22403715
Affinity Capture-MSPMID:22119525
nak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
fic1C2 domain protein Fic1 Affinity Capture-MSPMID:19139265
moc3transcription factor Moc3 Two-hybridPMID:19682301
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External References
Database Identifier Description
NBRP SPBC19C2.07 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC19C2.07 Retrieval of eukaryotic orthologs
BioGrid SPBC19C2.07 BioGRID Interaction Datasets
Bähler Lab SPBC19C2.07 Cell Cycle Expression Profile
Bähler Lab SPBC19C2.07 Meiosis/Sporulation Expression Profies
Bähler Lab SPBC19C2.07 Pheromone response/mating expression profiles
Bähler Lab SPBC19C2.07 Environmental stress expression profiles
Bähler Lab SPBC19C2.07 Bähler Lab Transcriptome Viewer
Cyclebase SPBC19C2.07 Cell Cycle Data
PInt SPBC19C2.07 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC19C2.07 Entrez Gene
KEGGMAP00030
IntEnz4.1.2.13
KEGGMAP00051
KEGGMAP00010
KEGGMAP00710
WikiGene2540767fructose-bisphosphate aldolase Fba1
Uniprot_genenameFBA1
EntrezGene2540767fructose-bisphosphate aldolase Fba1
SPD / RIKEN40/40C08Orfeome Localization Data
UniProtKB/SwissProtP36580Fructose-bisphosphate aldolase
ModBaseP36580Database of comparative protein structure models
Pfam Protein DomainsP36580Pfam Domain Arrangement
RefSeq PeptideNP_595692fructose-bisphosphate aldolase Fba1
RefSeq mRNANM_001021589972h- fructose-bisphosphate aldolase Fba1 (fba1), mRNA
European Nucleotide ArchiveBAA04237ENA Protein Mapping
European Nucleotide ArchiveCAB52034ENA Protein Mapping
UniParcUPI0000125829UniProt Archive

Literature for fba1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013