cct3 (SPBC1A4.08c)

Gene Standard Namecct3 ChromosomeII
Systematic IDSPBC1A4.08c Gene Start1992652
Synonyms Gene End1990416
Productchaperonin-containing T-complex gamma subunit Cct3 Gene Length2237
Feature Typeprotein coding CDS Start1992463
Name Description CDS End1990769
Characterisation Statuspublished CDS Length1695

Ensembl Gene Location
  1. SPBC1A4.04
  2. blt1
  3. tam41
  4. SPBC1A4.07c
  5. cct3
  6. SPBC1A4.11c
  7. SPBC1A4.09
  8. pmc1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002061inviable vegetative cell populationMicroscopycct3delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005524ATP bindingIEAUniProtKB:KW-0067GO_REF:0000037
GO:0051082unfolded protein bindingISOSGD:S000003551GO_REF:0000024
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006457protein foldingISOSGD:S000003551GO_REF:0000024
GO:0007010cytoskeleton organizationISOSGD:S000003551GO_REF:0000024
GO:0007021tubulin complex assemblyICGO:0005832GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005737cytoplasmISOSGD:S000003551GO_REF:0000024
GO:0005829cytosolIDAPMID:16823372
GO:0005832chaperonin-containing T-complexIDAPMID:19040720
GO:0005856cytoskeletonISOSGD:S000003551GO_REF:0000024
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
119926521992439
219924001992327
319922561990416

References

Region Start End Reference
three_prime_UTR19907681990416PMID:21511999
three_prime_UTR19907681990416PMID:21511999
five_prime_UTR19926521992464PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00118 IPR002423 Pfam Chaperonin Cpn60/TCP-1 31 521 10
PS00750 IPR002194 Prosite Patterns Chaperonin TCP-1, conserved site 36 48 8
PS00751 IPR002194 Prosite Patterns Chaperonin TCP-1, conserved site 57 73 8
PS00995 IPR002194 Prosite Patterns Chaperonin TCP-1, conserved site 85 93 7
G3DSA:1.10.560.10 Gene3D 2 139 9
G3DSA:1.10.560.10 Gene3D 401 521 9
G3DSA:3.30.260.10 Gene3D 144 210 8
G3DSA:3.30.260.10 Gene3D 372 400 8
G3DSA:3.50.7.10 Gene3D 211 371 10
SSF54849 SuperFamily 142 213 10
SSF54849 SuperFamily 367 402 10
SSF48592 IPR002423 SuperFamily 403 521 9
SSF48592 IPR002423 SuperFamily 13 142 9
SSF52029 SuperFamily 210 376 10
PR00304 IPR017998 PRINTS Chaperone tailless complex polypeptide 1 (TCP-1) 405 417 8
PR00304 IPR017998 PRINTS Chaperone tailless complex polypeptide 1 (TCP-1) 85 104 8
PR00304 IPR017998 PRINTS Chaperone tailless complex polypeptide 1 (TCP-1) 33 49 8
PR00304 IPR017998 PRINTS Chaperone tailless complex polypeptide 1 (TCP-1) 55 73 8
PR00304 IPR017998 PRINTS Chaperone tailless complex polypeptide 1 (TCP-1) 371 393 8
PTHR11353 IPR002423 hmmpanther Chaperonin Cpn60/TCP-1 1 528 10
PTHR11353:SF24 IPR012719 hmmpanther 1 528 1
TIGR02344 IPR012719 tigrfam T-complex protein 1, gamma subunit 4 526 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:18257517
PMID:19547744

Protein Properties

Ave. residue weight 110.76 Da
Charge 5.00
Isoelectric point 7.28
Molecular weight 58.48 kDa
Number of residues 528
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide8680.03PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide34882.57PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.4PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide11PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
far8SIP/FAR complex striatin subunit, Far8/Csc3 Affinity Capture-MSPMID:22119525
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
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External References
Database Identifier Description
NBRP SPBC1A4.08c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC1A4.08c Retrieval of eukaryotic orthologs
BioGrid SPBC1A4.08c BioGRID Interaction Datasets
Bähler Lab SPBC1A4.08c Cell Cycle Expression Profile
Bähler Lab SPBC1A4.08c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC1A4.08c Pheromone response/mating expression profiles
Bähler Lab SPBC1A4.08c Environmental stress expression profiles
Bähler Lab SPBC1A4.08c Bähler Lab Transcriptome Viewer
Cyclebase SPBC1A4.08c Cell Cycle Data
PInt SPBC1A4.08c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC1A4.08c Entrez Gene
WikiGene2540567chaperonin-containing T-complex gamma subunit Cct3
Uniprot_genenameCCT3
EntrezGene2540567chaperonin-containing T-complex gamma subunit Cct3
SPD / RIKEN35/35D01Orfeome Localization Data
UniProtKB/SwissProtO74341T-complex protein 1 subunit gamma
ModBaseO74341Database of comparative protein structure models
Pfam Protein DomainsO74341Pfam Domain Arrangement
RefSeq PeptideNP_595810chaperonin-containing T-complex gamma subunit Cct3
RefSeq mRNANM_001021713972h- chaperonin-containing T-complex gamma subunit Cct3 (cct3), mRNA
European Nucleotide ArchiveCAA20112ENA Protein Mapping
UniParcUPI0000136B01UniProt Archive

Literature for cct3
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013