sec13 (SPBC215.15)

Gene Standard Namesec13 Characterisation Statuspublished
Systematic IDSPBC215.15 Feature Typeprotein coding
Synonyms Name Description
ProductCOPII-coated vesicle component Sec13 Product Size297aa, 32.57 kDa
Genomic Location Chromosome II, 4059950-4061230 (1281nt); CDS:4060033-4061002 (970nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
barrier septum assembly43
Annotation ExtensionEvidenceWith/FromReference
ER to Golgi vesicle-mediated transport77
Annotation ExtensionEvidenceWith/FromReference
intracellular protein transport338
Annotation ExtensionEvidenceWith/FromReference
nuclear pore organization2
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
COPII vesicle coat8
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
endoplasmic reticulum594
Annotation ExtensionEvidenceWith/FromReference
nuclear pore53
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
plasma membrane247
Annotation ExtensionEvidenceWith/FromReference
Seh1-associated complex7
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopynot recorded (unrecorded)PMID:118210541338
Target Of
FYPO affected by mutation in hub1 ubiquitin-like protein modifier Hub1 PMID:15620657
FYPO affected by mutation in snu66 U4/U6 x U5 tri-snRNP complex subunit Snu66 PMID:15620657
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00400 Pfam IPR001680 WD40 repeat 200 236 104
PF00400 Pfam IPR001680 WD40 repeat 45 82 104
PF00400 Pfam IPR001680 WD40 repeat 93 127 104
PF00400 Pfam IPR001680 WD40 repeat 138 186 104
PF00400 Pfam IPR001680 WD40 repeat 14 37 104
SM00320 SMART IPR001680 WD40 repeat 245 283 112
SM00320 SMART IPR001680 WD40 repeat 194 237 112
SM00320 SMART IPR001680 WD40 repeat 134 187 112
SM00320 SMART IPR001680 WD40 repeat 1 37 112
SM00320 SMART IPR001680 WD40 repeat 88 129 112
SM00320 SMART IPR001680 WD40 repeat 42 83 112
PS50082 Prosite Profiles IPR001680 WD40 repeat 49 82 100
PS50294 Prosite Profiles IPR017986 WD40-repeat-containing domain 5 246 104
PS50082 Prosite Profiles IPR001680 WD40 repeat 201 236 100
PTHR11024 HMMPANTHER 1 297 2 Gene3D IPR015943 WD40/YVTN repeat-like-containing domain 6 294 145
SSF50978 SuperFamily IPR017986 WD40-repeat-containing domain 10 289 135

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000190WD repeat proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000190

Protein Properties

Ave. residue weight 109.66 Da
Charge -7.00
Isoelectric point 5.11
Molecular weight 32.57 kDa
Number of residues 297
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
55757during GO:0000080PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
55570during GO:0000084PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
57145during GO:0000085PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
51393during GO:0000087PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
54497during GO:0072690PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
49137.4during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
32755.82during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
8.4during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
1.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3092
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in eukaryotes only2497

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
nup189nucleoporin Nup98 and Nup96 Reconstituted ComplexPMID:22955883
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
sec31COPII-coated vesicle component Sec31 (predicted) Two-hybridPMID:23695164
External References
Database Identifier Description
NBRP SPBC215.15 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC215.15 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC215.15 BioGRID Interaction Datasets
Expression Viewer SPBC215.15 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC215.15 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC215.15 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC215.15 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC215.15 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC215.15 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC215.15 Cell Cycle Data
GEO SPBC215.15 GEO profiles
PInt SPBC215.15 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC215.15 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC215.15 Fission yeast phenotypic data & analysis
SPD / RIKEN13/13G12Orfeome Localization Data
UniProtKB/SwissProtO94319Protein transport protein sec13
ModBaseO94319Database of comparative protein structure models
STRINGO94319Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596692COPII-coated vesicle component Sec13
RefSeq mRNANM_001022615972h- COPII-coated vesicle component Sec13 (sec13), mRNA
European Nucleotide ArchiveCAA22129.1ENA Protein Mapping
UniParcUPI000006AA3EUniProt Archive

Literature for sec13

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014