SPBC21C3.09c

Gene Standard NameUnassigned ChromosomeII
Systematic IDSPBC21C3.09c Gene Start3812481
Synonyms Gene End3810897
Productfumarylacetoacetate hydrolase family protein (predicted) Gene Length1585
Feature Typeprotein coding CDS Start3812188
Name Description CDS End3811374
Characterisation Statusbiological_role_inferred CDS Length815

Ensembl Gene Location
  1. SPBC21C3.03
  2. SPBC21C3.04c
  3. sap62
  4. SPBC21C3.06
  5. SPBC21C3.07c
  6. SPNCRNA.1642
  7. car2
  8. SPBC21C3.09c
  9. SPNCRNA.1643
  10. SPBC21C3.10c
  11. SPBTRNALYS.09
  12. SPBTRNATYR.04
  13. ubx4
  14. SPBC21C3.12c
  15. rps1901
  16. SPBC21C3.14c
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPBC21C3.09cdelta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0016787hydrolase activityISMPFAM:PF01557GO_REF:0000001
GO:0046872metal ion bindingIEAUniProtKB:KW-0479GO_REF:0000037
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006572tyrosine catabolic processISMPFAM:PF01557GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005739mitochondrionISSUniProtKB:P53889GO_REF:0000001
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
138124813812142
238119923810897

References

Region Start End Reference
three_prime_UTR38113733810897PMID:21511999
three_prime_UTR38113733810897PMID:21511999
five_prime_UTR38124813812189PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF01557 IPR002529 Pfam Fumarylacetoacetase, C-terminal 7 200 1
G3DSA:3.90.850.10 IPR011234 Gene3D 2 200 1
SSF56529 IPR011234 SuperFamily 4 200 1
PTHR11820:SF7 hmmpanther 7 219 1
PTHR11820 hmmpanther 7 219 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.38 Da
Charge 6.50
Isoelectric point 9.41
Molecular weight 24.17 kDa
Number of residues 221
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide15326.76PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide7990.87PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.1PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide5.6PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in bacteria
conserved in metazoa
conserved in vertebrates
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
res1MBF transcription factor complex subunit Res1 Positive GeneticPMID:22681890
prw1Clr6 histone deacetylase complex subunit Prw1 Positive GeneticPMID:22681890
vps35retromer complex subunit Vps35 Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPBC21C3.09c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC21C3.09c Retrieval of eukaryotic orthologs
BioGrid SPBC21C3.09c BioGRID Interaction Datasets
Bähler Lab SPBC21C3.09c Cell Cycle Expression Profile
Bähler Lab SPBC21C3.09c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC21C3.09c Pheromone response/mating expression profiles
Bähler Lab SPBC21C3.09c Environmental stress expression profiles
Bähler Lab SPBC21C3.09c Bähler Lab Transcriptome Viewer
Cyclebase SPBC21C3.09c Cell Cycle Data
PInt SPBC21C3.09c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC21C3.09c Entrez Gene
WikiGene2540605fumarylacetoacetate (FAA) hydrolase
EntrezGene2540605fumarylacetoacetate (FAA) hydrolase
UniProtKB/SwissProtQ9P7L4Uncharacterized hydrolase C21C3.09c
ModBaseQ9P7L4Database of comparative protein structure models
Pfam Protein DomainsQ9P7L4Pfam Domain Arrangement
RefSeq PeptideNP_596589fumarylacetoacetate (FAA) hydrolase
RefSeq mRNANM_001022509972h- fumarylacetoacetate (FAA) hydrolase (SPBC21C3.09c), mRNA
European Nucleotide ArchiveBAA87171ENA Protein Mapping
European Nucleotide ArchiveCAB76045ENA Protein Mapping
SPD / RIKEN10/10E01Orfeome Localization Data
UniParcUPI000006A6FEUniProt Archive

Literature for SPBC21C3.09c
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013