nif1 (SPBC23G7.04c)

Gene Standard Namenif1 ChromosomeII
Systematic IDSPBC23G7.04c Gene Start2103827
Synonyms Gene End2101254
ProductSEL1 repeat protein Nif1 Gene Length2574
Feature Typeprotein coding CDS Start2103491
Name Description CDS End2101446
Characterisation Statuspublished CDS Length2046

Ensembl Gene Location
  1. edc3
  2. SPBC18E5.10
  3. SPNCRNA.536
  4. mas2
  5. SPBC18E5.13
  6. ctr6
  7. nif1
  8. SPNCRNA.387
  9. sui1
  10. SPBC23G7.06c
  11. cms1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000023small cellnif1delta (deletion)deletionPMID:9135149
FYPO:0000648small viable vegetative cellMicroscopynif1delta (deletion)deletionPECO:0000137PMID:22624651
FYPO:0002060viable vegetative cell populationMicroscopynif1delta (deletion)deletionPMID:20473289
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0010972negative regulation of G2/M transition of mitotic cell cycleIMPPMID:9135149
IMPPMID:22624651
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005829cytosolIDAPMID:16823372
GO:0032153cell division siteIDAPMID:16823372
GO:0035838growing cell tip
exists_during pseudohyphal growthIDAPMID:20870879
GO:0051286cell tipIDAPMID:20870879
IDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
121038272101254

References

Region Start End Reference
three_prime_UTR21014452101254PMID:21511999
three_prime_UTR21014452101254PMID:21511999
five_prime_UTR21038272103492PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
SM00671 IPR006597 SMART Sel1-like 583 618 7
SM00671 IPR006597 SMART Sel1-like 547 582 7
G3DSA:1.25.40.10 IPR011990 Gene3D 450 515 55
G3DSA:1.25.40.10 IPR011990 Gene3D 550 617 55
SSF81901 SuperFamily 449 510 9
SSF81901 SuperFamily 545 616 9
Coil ncoils Rabaptin coiled-coil domain 60 81 974
PTHR11102 hmmpanther 254 632 7
PTHR11102:SF36 hmmpanther 254 632 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000212SEL1 repeat proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000212

Protein Properties

Ave. residue weight 110.79 Da
Charge 6.50
Isoelectric point 6.91
Molecular weight 75.45 kDa
Number of residues 681
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide2030.04PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.1PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide3.8PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi only
conserved in fungi
conserved in eukaryotes
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
rad57RecA family ATPase Rad57/Rhp57 Synthetic Growth DefectPMID:18931302
cdr1NIM1 family serine/threonine protein kinase Cdr1/Nim1 Phenotypic EnhancementPMID:22624651
tlg2SNARE Tlg2 (predicted) Synthetic Growth DefectPMID:18931302
for3formin For3 Synthetic Growth DefectPMID:18931302
sty1MAP kinase Sty1 Phenotypic EnhancementPMID:22624651
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
cdr1NIM1 family serine/threonine protein kinase Cdr1/Nim1 Two-hybridPMID:9135149
Affinity Capture-Western
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External References
Database Identifier Description
NBRP SPBC23G7.04c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC23G7.04c Retrieval of eukaryotic orthologs
BioGrid SPBC23G7.04c BioGRID Interaction Datasets
Bähler Lab SPBC23G7.04c Cell Cycle Expression Profile
Bähler Lab SPBC23G7.04c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC23G7.04c Pheromone response/mating expression profiles
Bähler Lab SPBC23G7.04c Environmental stress expression profiles
Bähler Lab SPBC23G7.04c Bähler Lab Transcriptome Viewer
Cyclebase SPBC23G7.04c Cell Cycle Data
PInt SPBC23G7.04c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC23G7.04c Entrez Gene
WikiGene2540468SEL1 repeat protein Nif1
Uniprot_genenameNIF1
EntrezGene2540468SEL1 repeat protein Nif1
SPD / RIKEN33/33F08Orfeome Localization Data
UniProtKB/SwissProtP87159Mitosis inhibitor nif1
ModBaseP87159Database of comparative protein structure models
Pfam Protein DomainsP87159Pfam Domain Arrangement
RefSeq PeptideNP_595862SEL1 repeat protein Nif1
RefSeq mRNANM_001021767972h- SEL1 repeat protein Nif1 (nif1), mRNA
European Nucleotide ArchiveAAC49705ENA Protein Mapping
European Nucleotide ArchiveCAA22620ENA Protein Mapping
UniParcUPI000013007AUniProt Archive

Literature for nif1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013