rpp202 (SPBC23G7.15c)

Gene Standard Namerpp202 Characterisation Statuspublished
Systematic IDSPBC23G7.15c Feature Typeprotein coding
Synonymsrpa4, rpp2-2 Name Description
Product60S acidic ribosomal protein A4 Product Size110aa, 11.12 kDa
Genomic Location Chromosome II, 2128518-2127990 (529nt); CDS:2128410-2128032 (379nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003735structural constituent of ribosomeISOSGD:S000005399GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002182cytoplasmic translational elongationNASGO_REF:0000051193
GO:0006414translational elongationISOSGD:S000005399GO_REF:0000024221
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0022625cytosolic large ribosomal subunitISOSGD:S000005399GO_REF:000002482
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyrpp202ΔNullPMID:204732893730
Microscopyrpp202ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001489inviable vegetative cellCell growth assayrpa4-Not specifiedPMID:23256551191
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyrpp202ΔNullPECO:0000005, PECO:0000137PMID:23697806
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00428 Pfam IPR001813 Ribosomal protein L10/L12 17 109 7
PTHR21141 HMMPANTHER 1 110 8
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 21 32 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 82 96 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 97 108 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 36 47 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 101.09 Da
Charge -16.00
Isoelectric point 3.68
Molecular weight 11.12 kDa
Number of residues 110

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
present during mitotic M phase
present during mitotic M phaseS100PMID:21712547
present during mitotic M phase
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
336935during GO:0000080PECO:0000005,
mass spectrometry evidencePMID:24763107
345427during GO:0000084PECO:0000005,
mass spectrometry evidencePMID:24763107
333782during GO:0000085PECO:0000005,
mass spectrometry evidencePMID:24763107
327473during GO:0000087PECO:0000005,
mass spectrometry evidencePMID:24763107
56268.32during GO:0072690PECO:0000014,
experimental evidencePMID:23101633
335692during GO:0072690PECO:0000005,
mass spectrometry evidencePMID:24763107
39842.98during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
92during GO:0072690PECO:0000014,
experimental evidencePMID:23101633
9during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
experimental evidencePMID:23101633
Species Distribution
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in archaea237

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
sre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:21504829
mis4adherin, cohesin loading factor Mis4 Negative GeneticPMID:23050226
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
zfs1CCCH tandem zinc finger protein, human Tristetraprolin homolog Zfs1, involved in mRNA catabolism Two-hybridPMID:19682301
sds23PP2A-type phosphatase inhibitor Sds23/Moc1 Two-hybridPMID:19682301
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPBC23G7.15c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC23G7.15c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC23G7.15c BioGRID Interaction Datasets
Expression Viewer SPBC23G7.15c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC23G7.15c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC23G7.15c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC23G7.15c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC23G7.15c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC23G7.15c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC23G7.15c Cell Cycle Data
GEO SPBC23G7.15c GEO profiles
PInt SPBC23G7.15c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC23G7.15c Peptides identified in tandem mass spectrometry proteomics experiments
WikiGene254058760S acidic ribosomal protein P2B subunit
EntrezGene254058760S acidic ribosomal protein P2B subunit
SPD / RIKEN39/39G08Orfeome Localization Data
UniProtKB/SwissProtP1747860S acidic ribosomal protein P2-beta
ModBaseP17478Database of comparative protein structure models
STRINGP17478Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59587360S acidic ribosomal protein P2B subunit
RefSeq mRNANM_001021779972h- 60S acidic ribosomal protein P2B subunit (rpp202), mRNA
European Nucleotide ArchiveAAA35337ENA Protein Mapping
European Nucleotide ArchiveAAA35337.1ENA Protein Mapping
European Nucleotide ArchiveCAA22631ENA Protein Mapping
European Nucleotide ArchiveCAA22631.1ENA Protein Mapping
UniParcUPI000013426EUniProt Archive

Literature for rpp202

Search: Europe PMC or PubMed

Release Version: PomBase:22_45 - 08 Aug 2014