rpp202 (SPBC23G7.15c)


Gene Standard Namerpp202 Characterisation Statuspublished
Systematic IDSPBC23G7.15c Feature Typeprotein coding
Synonymsrpa4, rpp2-2 Name Description
Product60S acidic ribosomal protein A4 Product Size110aa, 11.12 kDa
Genomic Location Chromosome II, 2128518-2127990 (529nt); CDS:2128410-2128032 (379nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translational elongation194
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2314
Annotation ExtensionEvidenceWith/FromReference
cytosolic large ribosomal subunit83
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationrpp202ΔNull3809

Cell Phenotype

Term NameAlleleExpressionCount
inviable vegetative cellrpa4-Not specified1258
viable vegetative cell with normal cell morphologyrpp202ΔNull3094
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2128518..2128102, 2128055..2127990
mRNA2128518..2127990
5' UTR2128518..2128411PMID:21511999
CDS2128410..2128102, 2128055..2128032
3' UTR2128031..2127990PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00428 Pfam 17 109 7
PTHR21141 HMMPANTHER 1 110 8
MF_01478 hamap IPR027534 Ribosomal protein L12 family 2 110 6
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 36 47 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 82 96 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 97 108 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 21 32 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 101.09 Da
Charge -16.00
Isoelectric point 3.68
Molecular weight 11.12 kDa
Number of residues 110
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS100 1672
present during mitotic M phaseS86
present during mitotic M phaseS100
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S86 PMID:21712547
experimental evidence S100 PMID:24763107
present during mitotic M phase experimental evidence S100 PMID:21712547
O-phospho-L-threonine 698
present during mitotic M phaseT85
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence T85 PMID:21712547
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
336935during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
345427during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
333782during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
327473during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
56268.32during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
335692during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
39842.98during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
92during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
9during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4603
conserved in eukaryotes4514
conserved in metazoa3424
conserved in vertebrates3399
conserved in archaea238
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
binds DNA-binding domain construct withsds23PP2A-type phosphatase inhibitor Sds23/Moc1 Two-hybridPMID:19682301
binds DNA-binding domain construct withzfs1CCCH tandem zinc finger protein, human Tristetraprolin homolog Zfs1, involved in mRNA catabolism Two-hybridPMID:19682301
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withdsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
negative genetic interaction withmis4adherin, cohesin loading factor Mis4 Negative GeneticPMID:23050226
negative genetic interaction withsre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:21504829
External References
Database Identifier Description
NBRP SPBC23G7.15c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC23G7.15c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC23G7.15c BioGRID Interaction Datasets
Expression Viewer SPBC23G7.15c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC23G7.15c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC23G7.15c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC23G7.15c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC23G7.15c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC23G7.15c Transcriptome Viewer (Bähler Lab)
GEO SPBC23G7.15c GEO profiles
PInt SPBC23G7.15c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC23G7.15c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC23G7.15c Fission yeast phenotypic data & analysis
Cyclebase SPBC23G7.15c.1 Cell Cycle Data
SPD / RIKEN39/39G08Orfeome Localization Data
UniProtKB/SwissProtP1747860S acidic ribosomal protein P2-beta
ModBaseP17478Database of comparative protein structure models
STRINGP17478Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59587360S acidic ribosomal protein P2B
RefSeq mRNANM_001021779972h- 60S acidic ribosomal protein P2B (rpp202), mRNA
European Nucleotide ArchiveAAA35337.1ENA Protein Mapping
European Nucleotide ArchiveCAA22631.1ENA Protein Mapping
UniParcUPI000013426EUniProt Archive

Literature for rpp202

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015