ctr6 (SPBC23G7.16)


Gene Standard Namectr6 Characterisation Statuspublished
Systematic IDSPBC23G7.16 Feature Typeprotein coding
Synonyms Name Description
Productvacuolar copper transporter Ctr6 Product Size148aa, 16.75 kDa
Genomic Location Chromosome II, 2100018-2101253 (1236nt); CDS:2100273-2101061 (789nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005375copper ion transmembrane transporter activityIEAIPR007274GO_REF:00000025
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0035434copper ion transmembrane transportIDAPMID:122440507
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0000329fungal-type vacuole membraneIDAPMID:1224405091
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371016
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyctr6ΔNullPMID:204732893755
Microscopyctr6ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopyctr6ΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Target Of
RelationshipGeneProductReference
regulated by cuf1 nutritional copper sensing transcription factor Cuf1 PMID:12244050
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
121000182100317
221003872100412
321005202100780
421008752100896
521009692101253

UTRs

Region Start End Reference
three_prime_UTR21010622101253PMID:21511999
five_prime_UTR21000182100272PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04145 Pfam IPR007274 Ctr copper transporter 14 133 3
TMhelix TMHMM 105 127 959
TMhelix TMHMM 32 54 959
PTHR12483 HMMPANTHER IPR007274 Ctr copper transporter 1 133 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 113.16 Da
Charge 9.50
Isoelectric point 9.21
Molecular weight 16.75 kDa
Number of residues 148
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
34196.19during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
21424.79during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
1.7during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
3.1during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
Misc
DescriptionQualifierReferenceCount
promoter contains CuSE3
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in eukaryotes only2485
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ctr4copper transporter complex subunit Ctr4 Phenotypic EnhancementPMID:12244050
External References
Database Identifier Description
NBRP SPBC23G7.16 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC23G7.16 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC23G7.16 BioGRID Interaction Datasets
Expression Viewer SPBC23G7.16 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC23G7.16 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC23G7.16 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC23G7.16 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC23G7.16 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC23G7.16 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC23G7.16 Cell Cycle Data
GEO SPBC23G7.16 GEO profiles
PInt SPBC23G7.16 Protein-Protein Interaction Predictor (Bähler Lab)
EntrezGene2540641vacuolar copper transporter Ctr6
WikiGene2540641vacuolar copper transporter Ctr6
SPD / RIKEN09/09H10Orfeome Localization Data
UniProtKB/SwissProtQ9USV7Copper transport protein ctr6
ModBaseQ9USV7Database of comparative protein structure models
StringQ9USV7Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595861vacuolar copper transporter Ctr6
RefSeq mRNANM_001021766972h- vacuolar copper transporter Ctr6 (ctr6), mRNA
European Nucleotide ArchiveCAB58134ENA Protein Mapping
UniParcUPI0000128661UniProt Archive

Literature for ctr6

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014