sec9 (SPBC26H8.02c)

Gene Standard Namesec9 Characterisation Statuspublished
Systematic IDSPBC26H8.02c Feature Typeprotein coding
Synonyms Name Description
ProductSNAP-25 homologue, t-SNARE component Sec9 Product Size419aa, 46.43 kDa
Genomic Location Chromosome II, 3944032-3941984 (2049nt); CDS:3943744-3942485 (1260nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
SNAP receptor activity19
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
ascospore formation58
Annotation ExtensionEvidenceWith/FromReference
ascospore-type prospore assembly24
Annotation ExtensionEvidenceWith/FromReference
Golgi to plasma membrane transport12
Annotation ExtensionEvidenceWith/FromReference
intracellular protein transport373
Annotation ExtensionEvidenceWith/FromReference
prospore membrane biogenesis3
Annotation ExtensionEvidenceWith/FromReference
vesicle fusion8
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
prospore membrane33
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell population1468

Cell Phenotype

Term NameGenotypesCount
inviable sporesec9Δ476

FYPO Multi-allele Phenotypes

Population Phenotype

Term NameGenotypes
viable vegetative cell populationsec9+, psy1-S1 (L139P)

Cell Phenotype

Term NameGenotypes
normal sporulationsec9+, psy1-S1 (L139P)
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR3944032..3943745PMID:21511999
3' UTR3942484..3941984PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
SM00397 SMART IPR000727 Target SNARE coiled-coil homology domain 351 418 10
SM00397 SMART IPR000727 Target SNARE coiled-coil homology domain 198 265 10
PS50192 Prosite Profiles IPR000727 Target SNARE coiled-coil homology domain 356 418 9
PTHR19305:SF8 HMMPANTHER 100 143 1
PTHR19305:SF8 HMMPANTHER 159 418 1
PTHR19305 HMMPANTHER 100 143 1
PTHR19305 HMMPANTHER 159 418 1 Gene3D ATP-binding sugar transporter-like protein 190 266 12 Gene3D ATP-binding sugar transporter-like protein 344 418 12
SSF58038 SuperFamily 192 262 9
SSF58038 SuperFamily 346 418 9
Coil ncoils Predicted coiled-coil protein (DUF2205) 241 261 1049

View domain organization at Pfam

Term IDTerm NameReferenceCount
PBO:0000345SNARETemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000345

Protein Properties

Ave. residue weight 110.81 Da
Charge -2.50
Codon Adaptation Index 0.43
Isoelectric point 6.09
Molecular weight 46.43 kDa
Number of residues 419

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 2293
present during mitotic M phaseS396
present during mitotic M phaseS389
S138, S141, S396
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S396 PMID:21712547
present during mitotic M phase experimental evidence S389 PMID:21712547
experimental evidence S396 PMID:24763107
IDA S138 PMID:25720772
IDA S141 PMID:25720772
O-phospho-L-threonineT144 1087
Annotation ExtensionEvidenceResidueReference
IDA T144 PMID:25720772
O-phosphorylated residueS138,S141, S141,T144 2461
Annotation ExtensionEvidenceResidueReference
IDA S141,T144 PMID:25720772
IDA S138,S141 PMID:25720772
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for sec9 (SPBC26H8.02c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
14800during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
12994during GO:0000084PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
15766during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
11812during GO:0000087PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
10942during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
609.31during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
4.9during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
2.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Disease Association
Taxonomic Conservation
conserved in fungi4608
conserved in eukaryotes4516
conserved in metazoa3498
conserved in vertebrates3473
conserved in eukaryotes only2525

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPBC26H8.02c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
overexpression rescuespsy1SNARE Psy1 Dosage RescuePMID:19202289
overexpression rescuessyb1SNAP receptor, synaptobrevin family Dosage RescuePMID:23709180
rescued by overexpression ofpsy1SNARE Psy1 Dosage RescuePMID:16272747
rescuessyb1SNAP receptor, synaptobrevin family Phenotypic SuppressionPMID:23709180
External References
Database Identifier Description
NBRP SPBC26H8.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC26H8.02c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC26H8.02c BioGRID Interaction Datasets
Expression Viewer SPBC26H8.02c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC26H8.02c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC26H8.02c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC26H8.02c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC26H8.02c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC26H8.02c Transcriptome Viewer (Bähler Lab)
GEO SPBC26H8.02c GEO profiles
PInt SPBC26H8.02c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC26H8.02c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC26H8.02c Fission yeast phenotypic data & analysis
Cyclebase SPBC26H8.02c.1 Cell Cycle Data
SPD / RIKEN20/20B06Orfeome Localization Data
UniProtKB/SwissProtO74786Protein transport protein sec9
ModBaseO74786Database of comparative protein structure models
STRINGO74786Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596643protein transport protein
RefSeq mRNANM_001022565972h- protein transport protein (sec9), mRNA
European Nucleotide ArchiveCAA21094.1ENA Protein Mapping
UniParcUPI000006991BUniProt Archive

Literature for sec9

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017