sec9 (SPBC26H8.02c)

Gene Standard Namesec9 Characterisation Statuspublished
Systematic IDSPBC26H8.02c Feature Typeprotein coding
Synonyms Name Description
ProductSNAP-25 homologue, t-SNARE component Sec9 Product Size419aa, 46.43 kDa
Genomic Location Chromosome II, 3944032-3941984 (2049nt); CDS:3943744-3942485 (1260nt)

Ensembl Gene Location
GO Molecular Function

GO Slim Terms

membrane organization

Term NameCount
SNAP receptor activity19
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
ascospore formation62
Annotation ExtensionEvidenceWith/FromReference
ascospore-type prospore assembly24
Annotation ExtensionEvidenceWith/FromReference
Golgi to plasma membrane transport10
Annotation ExtensionEvidenceWith/FromReference
intracellular protein transport336
Annotation ExtensionEvidenceWith/FromReference
vesicle fusion9
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
prospore membrane28
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell population1443

Cell Phenotype

Term NameGenotypesCount
inviable sporesec9Δ474
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR3944032..3943745PMID:21511999
3' UTR3942484..3941984PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
SM00397 SMART IPR000727 Target SNARE coiled-coil homology domain 351 418 10
SM00397 SMART IPR000727 Target SNARE coiled-coil homology domain 198 265 10
PS50192 Prosite Profiles IPR000727 Target SNARE coiled-coil homology domain 356 418 9
PTHR19305:SF0 HMMPANTHER 101 418 1
PTHR19305 HMMPANTHER 101 418 1 Gene3D SNAP-25 344 418 12 Gene3D SNAP-25 190 266 12
SSF58038 SuperFamily 346 418 9
SSF58038 SuperFamily 192 262 9
Coil ncoils Rabaptin coiled-coil domain 241 261 1048

View domain organization at Pfam

Term IDTerm NameReferenceCount
PBO:0000345SNARETemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000345

Protein Properties

Ave. residue weight 110.81 Da
Charge -2.50
Codon Adpatation Index 0.43
Isoelectric point 6.09
Molecular weight 46.43 kDa
Number of residues 419

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1672
present during mitotic M phaseS389
present during mitotic M phaseS396
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S389 PMID:21712547
experimental evidence S396 PMID:24763107
present during mitotic M phase experimental evidence S396 PMID:21712547
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
14800during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
12994during GO:0000084PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
15766during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
11812during GO:0000087PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
609.31during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
10942during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
4.9during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
2.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Disease Association
Taxonomic Conservation
conserved in fungi4604
conserved in eukaryotes4514
conserved in metazoa3421
conserved in vertebrates3396
conserved in eukaryotes only2503

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
rescued by overexpression ofpsy1SNARE Psy1 Dosage RescuePMID:16272747
overexpression rescuessyb1SNAP receptor, synaptobrevin family Dosage RescuePMID:23709180
rescuessyb1SNAP receptor, synaptobrevin family Phenotypic SuppressionPMID:23709180
External References
Database Identifier Description
NBRP SPBC26H8.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC26H8.02c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC26H8.02c BioGRID Interaction Datasets
Expression Viewer SPBC26H8.02c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC26H8.02c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC26H8.02c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC26H8.02c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC26H8.02c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC26H8.02c Transcriptome Viewer (Bähler Lab)
GEO SPBC26H8.02c GEO profiles
PInt SPBC26H8.02c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC26H8.02c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC26H8.02c Fission yeast phenotypic data & analysis
Cyclebase SPBC26H8.02c.1 Cell Cycle Data
SPD / RIKEN20/20B06Orfeome Localization Data
UniProtKB/SwissProtO74786Protein transport protein sec9
ModBaseO74786Database of comparative protein structure models
STRINGO74786Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596643protein transport protein
RefSeq mRNANM_001022565972h- protein transport protein (sec9), mRNA
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveCAA21094ENA Protein Mapping
European Nucleotide ArchiveCAA21094.1ENA Protein Mapping
UniParcUPI000006991BUniProt Archive

Literature for sec9

Search: Europe PMC or PubMed

Release Version: PomBase:28_55 - 09 Sep 2015