sec9 (SPBC26H8.02c)


Gene Standard Namesec9 Characterisation Statuspublished
Systematic IDSPBC26H8.02c Feature Typeprotein coding
Synonyms Name Description
ProductSNAP-25 homologue, t-SNARE component Sec9 Product Size419aa, 46.43 kDa
Genomic Location Chromosome II, 3944032-3941984 (2049nt); CDS:3943744-3942485 (1260nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
SNAP receptor activity19
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
ascospore formation57
Annotation ExtensionEvidenceWith/FromReference
ascospore-type prospore assembly23
Annotation ExtensionEvidenceWith/FromReference
Golgi to plasma membrane transport9
Annotation ExtensionEvidenceWith/FromReference
intracellular protein transport316
Annotation ExtensionEvidenceWith/FromReference
vesicle fusion9
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
prospore membrane30
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell population1455
sec9Δ

Cell Phenotype

Term NameGenotypesCount
inviable sporesec9Δ476
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3944032..3941984
mRNA3944032..3941984
5' UTR3944032..3943745PMID:21511999
CDS3943744..3942485
3' UTR3942484..3941984PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
SM00397 SMART IPR000727 Target SNARE coiled-coil homology domain 198 265 10
SM00397 SMART IPR000727 Target SNARE coiled-coil homology domain 351 418 10
PS50192 Prosite Profiles IPR000727 Target SNARE coiled-coil homology domain 356 418 9
PTHR19305 HMMPANTHER 100 143 1
PTHR19305:SF8 HMMPANTHER 159 418 1
PTHR19305:SF8 HMMPANTHER 100 143 1
PTHR19305 HMMPANTHER 159 418 1
1.20.5.110 Gene3D Haemagglutinin/haemagglutinin-neuraminidase, paramyxovirus 344 418 12
1.20.5.110 Gene3D Haemagglutinin/haemagglutinin-neuraminidase, paramyxovirus 190 266 12
SSF58038 SuperFamily 346 418 9
SSF58038 SuperFamily 192 262 9
Coil ncoils Predicted coiled-coil protein (DUF2205) 241 261 1055

View domain organization at Pfam

Term IDTerm NameReferenceCount
PBO:0000345SNARETemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000345

Protein Properties

Ave. residue weight 110.81 Da
Charge -2.50
Codon Adaptation Index 0.43
Isoelectric point 6.09
Molecular weight 46.43 kDa
Number of residues 419
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 2289
present during mitotic M phaseS389
present during mitotic M phaseS396
S138, S141, S396
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S389 PMID:21712547
present during mitotic M phase experimental evidence S396 PMID:21712547
experimental evidence S396 PMID:24763107
IDA S141 PMID:25720772
IDA S138 PMID:25720772
O-phospho-L-threonineT144 1085
Annotation ExtensionEvidenceResidueReference
IDA T144 PMID:25720772
O-phosphorylated residueS138,S141, S141,T144 2457
Annotation ExtensionEvidenceResidueReference
IDA S141,T144 PMID:25720772
IDA S138,S141 PMID:25720772
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for sec9 (SPBC26H8.02c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
14800during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
12994during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
15766during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
11812during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
10942during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
609.31during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
4.9during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
2.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Disease Association
DescriptionQualifierReferenceCount
schizophrenia3
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4607
conserved in eukaryotes4517
conserved in metazoa3427
conserved in vertebrates3402
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPBC26H8.02c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
rescuessyb1SNAP receptor, synaptobrevin family Phenotypic SuppressionPMID:23709180
rescued by overexpression ofpsy1SNARE Psy1 Dosage RescuePMID:16272747
overexpression rescuessyb1SNAP receptor, synaptobrevin family Dosage RescuePMID:23709180
External References
Database Identifier Description
NBRP SPBC26H8.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC26H8.02c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC26H8.02c BioGRID Interaction Datasets
Expression Viewer SPBC26H8.02c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC26H8.02c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC26H8.02c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC26H8.02c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC26H8.02c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC26H8.02c Transcriptome Viewer (Bähler Lab)
GEO SPBC26H8.02c GEO profiles
PInt SPBC26H8.02c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC26H8.02c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC26H8.02c Fission yeast phenotypic data & analysis
Cyclebase SPBC26H8.02c.1 Cell Cycle Data
SPD / RIKEN20/20B06Orfeome Localization Data
UniProtKB/SwissProtO74786Protein transport protein sec9
ModBaseO74786Database of comparative protein structure models
STRINGO74786Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596643protein transport protein
RefSeq mRNANM_001022565972h- protein transport protein (sec9), mRNA
European Nucleotide ArchiveCAA21094.1ENA Protein Mapping
UniParcUPI000006991BUniProt Archive

Literature for sec9

Search: Europe PMC or PubMed

Release Version: PomBase:30_61 - 12 Sep 2016