sec9 (SPBC26H8.02c)


Gene Standard Namesec9 Characterisation Statuspublished
Systematic IDSPBC26H8.02c Feature Typeprotein coding
Synonyms Name Description
ProductSNAP-25 homologue, t-SNARE component Sec9 Product Size419aa, 46.43 kDa
Genomic Location Chromosome II, 3944032-3941984 (2049nt); CDS:3943744-3942485 (1260nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005484SNAP receptor activityISOSGD:S000003241GO_REF:000002419
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006893Golgi to plasma membrane transportISOSGD:S000003241GO_REF:000002410
GO:0030437ascospore formationIMPPMID:1627274767
GO:0031321ascospore-type prospore assemblyIMPPMID:1627274718
IGIpsy1PMID:16272747
GO:0006886intracellular protein transportNASGO_REF:0000051330
GO:0006906vesicle fusionISOSGD:S000004619GO_REF:000002411
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005628prospore membraneISOSGD:S000004619GO_REF:000002424
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopysec9ΔNullPMID:204732891331
Microscopynot recorded (unrecorded)PMID:16272747
Microscopysec9ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002151inviable spore459
penetrance FYPO_EXT:0000001Microscopysec9ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
139440323941984

UTRs

Region Coordinates Reference
five_prime_UTR3944032..3943745PMID:21511999
three_prime_UTR3942484..3941984PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
SM00397 SMART IPR000727 Target SNARE coiled-coil domain 351 418 10
SM00397 SMART IPR000727 Target SNARE coiled-coil domain 198 265 10
PS50192 Prosite Profiles IPR000727 Target SNARE coiled-coil domain 356 418 9
PTHR19305:SF0 HMMPANTHER 101 418 1
PTHR19305 HMMPANTHER 101 418 1
1.20.5.110 Gene3D 190 266 12
1.20.5.110 Gene3D 344 418 12
SSF58038 SuperFamily 192 262 9
SSF58038 SuperFamily 346 418 9
Coil ncoils Rabaptin coiled-coil domain 241 262 968

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000345SNARETemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000345

Protein Properties

Ave. residue weight 110.81 Da
Charge -2.50
Isoelectric point 6.09
Molecular weight 46.43 kDa
Number of residues 419
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineS389PMID:217125471669
present during mitotic M phase
S396PMID:24763107
present during mitotic M phaseS396PMID:21712547
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
14800during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
12994during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
15766during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
11812during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
609.31during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
10942during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
4.9during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
2.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Disease Association
DescriptionQualifierReferenceCount
schizophrenia2
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in eukaryotes only2487
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
syb1SNAP receptor, synaptobrevin family Phenotypic SuppressionPMID:23709180
Dosage Rescue
psy1SNARE Psy1 Dosage RescuePMID:16272747
External References
Database Identifier Description
NBRP SPBC26H8.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC26H8.02c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC26H8.02c BioGRID Interaction Datasets
Expression Viewer SPBC26H8.02c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC26H8.02c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC26H8.02c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC26H8.02c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC26H8.02c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC26H8.02c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC26H8.02c Cell Cycle Data
GEO SPBC26H8.02c GEO profiles
PInt SPBC26H8.02c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC26H8.02c Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN20/20B06Orfeome Localization Data
WikiGene2540623protein transport protein
EntrezGene2540623protein transport protein
UniProtKB/SwissProtO74786Protein transport protein sec9
ModBaseO74786Database of comparative protein structure models
STRINGO74786Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596643protein transport protein
RefSeq mRNANM_001022565972h- protein transport protein (sec9), mRNA
European Nucleotide ArchiveCAA21094ENA Protein Mapping
European Nucleotide ArchiveCAA21094.1ENA Protein Mapping
UniParcUPI000006991BUniProt Archive

Literature for sec9

Search: Europe PMC or PubMed

Release Version: PomBase:22_45 - 08 Aug 2014