ask1 (SPBC27.02c)

Gene Standard Nameask1 ChromosomeII
Systematic IDSPBC27.02c Gene Start1563675
Synonymsmug181 Gene End1562326
ProductDASH complex subunit Ask1 Gene Length1350
Feature Typeprotein coding CDS Start1563564
Name DescriptionMeiotically Upregulated Gene CDS End1562508
Characterisation Statuspublished CDS Length1057

Ensembl Gene Location
  1. SPNCRNA.1443
  2. SPNCRNA.1444
  3. rpl26
  4. SPBC29B5.04c
  5. SPBC27.01c
  6. SPNCRNA.1445
  7. ask1
  8. SPNCRNA.1446
  9. meu25
  10. SPNCRNA.1447
  11. uds1
  12. SPBC27.05
  13. mgr2
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000085sensitive to camptothecincompetitive growth assay evidenceask1delta (deletion)deletionPMID:20537132
FYPO:0000091sensitive to thiabendazolecompetitive growth assay evidenceask1delta (deletion)deletionPMID:20537132
FYPO:0000096sensitive to cadmiumCell growth assayask1delta (deletion)deletionPECO:0000012PMID:18684775
FYPO:0000266sensitive to DNA damaging agentscompetitive growth assay evidenceask1delta (deletion)deletionPMID:20537132
FYPO:0000269sensitive to microtubule depolymerizing drugscompetitive growth assay evidenceask1delta (deletion)deletionPMID:20537132
FYPO:0000271sensitive to salt stressCell growth assayask1delta (deletion)deletionPECO:0000012PMID:18684775
FYPO:0001491viable vegetative cellno_name (unrecorded)unrecordedPMID:16079914
Microscopyask1delta (deletion)deletionPMID:20473289
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0007052mitotic spindle organizationISOSGD:S000001535GO_REF:0000024
GO:0030437ascospore formationIMPPMID:16303567
GO:0030472mitotic spindle organization in nucleusIEAIPR013964GO_REF:0000002
GO:0031134sister chromatid biorientationTASPMID:16079914
GO:0034613cellular protein localization
has_input dam1IMPPMID:16079915
GO:0045132meiotic chromosome segregationIMPPMID:16303567
GO:0071276cellular response to cadmium ionIMPPMID:18684775
GO:0071585detoxification of cadmium ionIMPPMID:18684775
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0000778condensed nuclear chromosome kinetochore
exists_during mitotic cell cycleIDAPMID:16079914
GO:0000779condensed chromosome, centromeric region
exists_during mitotic prometaphaseIDAPMID:17035632
GO:0005634nucleusIDAPMID:16823372
GO:0005816spindle pole body
exists_during mitotic cell cycleIDAPMID:16079914
GO:0005829cytosolIDAPMID:16823372
GO:0005874microtubuleIEAUniProtKB:KW-0493GO_REF:0000037
GO:0042729DASH complex
exists_during mitotic cell cycleIDAPMID:16079914
GO:0044732mitotic spindle pole bodyIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
115636751563548
215634921563345
315632661562326

References

Region Start End Reference
three_prime_UTR15625071562326PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF08655 IPR013964 Pfam DASH complex subunit Ask1 7 71 1
Coil ncoils Rabaptin coiled-coil domain 274 295 974

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:16079914

Protein Properties

Ave. residue weight 112.68 Da
Charge -13.50
Isoelectric point 4.64
Molecular weight 34.59 kDa
Number of residues 307
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
expressed during meiosis PMID:16303567
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.3PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide0.85PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi only
conserved in fungi
conserved in eukaryotes
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
rhn1RNA polymerase II transcription termination factor homolog Negative GeneticPMID:18818364
rec24meiotic recombination protein Rec24 Positive GeneticPMID:22681890
srs2ATP-dependent DNA helicase, UvrD subfamily Negative GeneticPMID:18818364
SPAC2H10.01transcription factor, zf-fungal binuclear cluster type (predicted) Negative GeneticPMID:22681890
SPAC26H5.04vacuolar import and degradation protein Vid28 (predicted) Negative GeneticPMID:18818364
rrg9mitochondrial genome maintenance protein Rrg9 (predicted) Negative GeneticPMID:22681890
clr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
gfh1gamma tubulin complex subunit Gfh1 Negative GeneticPMID:22681890
rpp20360S acidic ribosomal protein P2C subunit Negative GeneticPMID:22681890
pli1SUMO E3 ligase Pli1 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
atb2tubulin alpha 2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
nup40nucleoporin Nup40 Negative GeneticPMID:18818364
git3G-protein coupled receptor Git3 Positive GeneticPMID:22681890
ero11ER oxidoreductin Ero1a Positive GeneticPMID:22681890
exg3glucan 1,3-beta-glucosidase Exg3 Positive GeneticPMID:22681890
mcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC1610.02cmitochondrial ribosomal protein subunit L1 (predicted) Negative GeneticPMID:22681890
SPAC227.11csensor for misfolded ER glycoproteins Yos9 (predicted) Positive GeneticPMID:22681890
rps2340S ribosomal protein S23 (predicted) Negative GeneticPMID:22681890
hta1histone H2A alpha Negative GeneticPMID:22681890
pmc2mediator complex subunit Pmc2/Med1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ase1antiparallel microtubule cross-linking factor Ase1 Positive GeneticPMID:18818364
bdf1Swr1 complex bromodomain subunit Brf1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
rps280240S ribosomal protein S28, Rps2802 Negative GeneticPMID:22681890
caf1CCR4-Not complex CAF1 family ribonuclease subunit Caf1 Negative GeneticPMID:18818364
mrc1mediator of replication checkpoint 1 Negative GeneticPMID:18818364
amk2AMP-activated protein kinase beta subunit Amk2 Negative GeneticPMID:18818364
poz1Pot1 associated protein Poz1 Negative GeneticPMID:22681890
SPAC227.10prefoldin subunit 2 (predicted) Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
pmc3mediator complex subunit Pmc3/Med27 Positive GeneticPMID:18818364
nup132nucleoporin Nup132 Negative GeneticPMID:22681890
atg4Atg8 deconjugator Atg4 (predicted) Positive GeneticPMID:22681890
mhf2FANCM-MHF complex subunit Mhf2 Negative GeneticPMID:22681890
SPBC25B2.08sequence orphan Positive GeneticPMID:22681890
mug114sequence orphan Positive GeneticPMID:22681890
pob3FACT complex subunit Pob3 Negative GeneticPMID:18818364
SPAC12B10.13proteasome-dependent catabolite inactivation protein, ubiquitin ligase complex subunit (predicted) Negative GeneticPMID:22681890
alp31tubulin specific chaperone cofactor A, Alp31 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
pck1protein kinase C (PKC)-like Pck1 Negative GeneticPMID:22681890
ubp3ubiquitin C-terminal hydrolase Ubp3 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
bob1prefoldin subunit 5 (predicted) Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
spo20sec14 cytosolic factor family Sec14 Negative GeneticPMID:22681890
raf2Rik1-associated factor Raf2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC22G7.07cmRNA (N6-adenosine)-methyltransferase (predicted) Negative GeneticPMID:22681890
rps10140S ribosomal protein S3a Negative GeneticPMID:22681890
SPCC1840.05cphosphoglucomutase (predicted) Negative GeneticPMID:22681890
SPCC584.01csulfite reductase NADPH flavoprotein subunit (predicted) Negative GeneticPMID:22681890
ies4Ino80 complex subunit Ies4 Negative GeneticPMID:22681890
vph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Positive GeneticPMID:18818364
SPCC622.03chypothetical protein Negative GeneticPMID:22681890
hif2Set3 complex subunit Hif2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
bio2biotin synthase Positive GeneticPMID:22681890
sld3DNA replication pre-initiation complex subunit Sld3 Positive GeneticPMID:22681890
ams2cell cycle regulated GATA-type transcription factor Ams2 Negative GeneticPMID:22681890
tps2trehalose-phosphate synthase Tps2 (predicted) Positive GeneticPMID:22681890
fml1ATP-dependent 3' to 5' DNA helicase, FANCM ortholog Fml1 Negative GeneticPMID:18818364
ppr5mitochondrial PPR repeat protein Ppr5 Positive GeneticPMID:22681890
sty1MAP kinase Sty1 Negative GeneticPMID:22681890
SPBC1604.16cRNA-binding protein, G-patch type (predicted) Positive GeneticPMID:22681890
rps250240S ribosomal protein S25 (predicted) Negative GeneticPMID:22681890
tfs1transcription elongation factor TFIIS Positive GeneticPMID:22681890
pex13peroxin 13 (predicted) Positive GeneticPMID:22681890
SPCC188.10cpseudogene Positive GeneticPMID:22681890
SPCC70.08cmethyltransferase (predicted) Negative GeneticPMID:22681890
SPCC1672.04cmitochondrial copper chaperone (predicted) Negative GeneticPMID:22681890
SPAC227.17cconserved protein Negative GeneticPMID:22681890
ppk26serine/threonine protein kinase, PAN complex subunit, Ppk26 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
rdp1RNA-directed RNA polymerase Rdp1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
dbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
trm10tRNA m(1)G methyltransferase Trm10 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC736.02sequence orphan Negative GeneticPMID:22681890
SPBC31F10.12RNA-binding protein Tma20 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
pac10prefoldin subunit 3 Pac10 (predicted) Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC338.14adenosine kinase (predicted) Positive GeneticPMID:22681890
bub3mitotic spindle checkpoint protein Bub3 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
not3CCR4-Not complex subunit Not3/5 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
arp6actin-like protein Arp6 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
dsk1SR protein-specific kinase Dsk1 Negative GeneticPMID:18818364
aps1diadenosine 5',5'''-p1,p6-hexaphosphate hydrolase Aps1 Positive GeneticPMID:22681890
SPAC694.02DEAD/DEAH box helicase Negative GeneticPMID:22681890
rpl70260S ribosomal protein L7 Negative GeneticPMID:22681890
rhp41DNA repair protein Rhp41 Synthetic Growth DefectPMID:18931302
pub1HECT-type ubiquitin-protein ligase E3 Pub1 Negative GeneticPMID:22681890
SPCC594.01DUF1769 family protein Negative GeneticPMID:22681890
ftp105Ubp5 interacting protein Ftp105 Positive GeneticPMID:18818364
tsf1mitochondrial translation elongation factor EF-Ts Tsf1 Negative GeneticPMID:22681890
sft1SNARE Sft1 (predicted) Negative GeneticPMID:22681890
SPAC56E4.07N-acetyltransferase (predicted) Positive GeneticPMID:22681890
SPAC13G6.09SSU-rRNA maturation protein Tsr4 homolog 2 (predicted) Negative GeneticPMID:22681890
SPAC2F7.17mitochondrial peptide chain release factor (predicted) Negative GeneticPMID:22681890
dsc4Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
laf1clr6 L associated factor 1 Laf1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPBC56F2.08cRNA-binding protein (predicted) Negative GeneticPMID:18818364
pds5cohesin-associated protein Pds5 Negative GeneticPMID:18818364
SPBC1347.09hexaprenyldihydroxybenzoate methyltransferase, Coq3 variant (predicted) Positive GeneticPMID:22681890
SPAC1296.01cphosphoacetylglucosamine mutase (predicted) Negative GeneticPMID:22681890
clp1Cdc14-related protein phosphatase Clp1/Flp1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
tif512translation elongation factor eIF5A (predicted) Positive GeneticPMID:22681890
rad2FEN-1 endonuclease Rad2 Negative GeneticPMID:22681890
SPBP4H10.16cphosphatase activator (predicted) Positive GeneticPMID:22681890
sdc1Dpy-30 domain protein Sdc1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
iwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:18818364
est1telomerase regulator Est1 Negative GeneticPMID:18818364
mto1MT organizer Mto1 Negative GeneticPMID:22681890
fin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
dcc1Ctf18 RFC-like complex subunit Dcc1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
omh6alpha-1,2-mannosyltransferase Omh6 (predicted) Negative GeneticPMID:22681890
mga2IPT/TIG ankyrin repeat containing transcription regulator of fatty acid biosynthesis (predicted) Negative GeneticPMID:18818364
spc34DASH complex subunit Spc34 Positive GeneticPMID:18818364
apq12nuclear membrane organization protein Apq12 (predicted) Negative GeneticPMID:22681890
SPBC1861.05pseudouridine-metabolizing bifunctional protein (predicted) Negative GeneticPMID:22681890
ctp1CtIP-related endonuclease Negative GeneticPMID:22681890
SPBC3B8.05diphthamide biosynthesis protein Dph1 (predicted) Positive GeneticPMID:22681890
dad1DASH complex subunit Dad1 Negative GeneticPMID:18818364
lub1WD repeat protein Lub1 Negative GeneticPMID:22681890
naa40histone N-acetyltransferase Naa40 (predicted) Negative GeneticPMID:22681890
swr1SNF2 family helicase Swr1 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
SPCC18.10pyridoxine-pyridoxal-pyridoxamine kinase (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC25B8.05tRNA-pseudouridine synthase (predicted) Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
sir2Sir2 family histone deacetylase Sir2 Positive GeneticPMID:18818364
pop2F-box/WD repeat protein Pop2 Negative GeneticPMID:22681890
SPAC2E1P3.05cfungal cellulose binding domain protein Negative GeneticPMID:22681890
spt2non-specific DNA binding protein Spt2 (predicted) Positive GeneticPMID:18818364
sdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Negative GeneticPMID:22681890
ers1RNA-silencing factor Ers1 Negative GeneticPMID:22681890
mug65spore wall assembly protein (predicted) Negative GeneticPMID:22681890
rps110240S ribosomal protein S11 (predicted) Negative GeneticPMID:22681890
ubp6ubiquitin C-terminal hydrolase Ubp6 Negative GeneticPMID:22681890
mak3histidine kinase Mak3 Negative GeneticPMID:22681890
zds1zds family protein phosphatase type A regulator Zds1 (predicted) Negative GeneticPMID:18818364
SPAC30D11.14cRNA-binding protein (predicted) Positive GeneticPMID:22681890
rxt2histone deacetylase complex subunit Rxt2 Negative GeneticPMID:22681890
set3histone lysine methyltransferase Set3 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
cut7kinesin-like protein Cut7 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC9.11sequence orphan Negative GeneticPMID:22681890
mto2MT organizer Mto2 Negative GeneticPMID:22681890
csi1chromosome segregation impaired protein 1 Synthetic LethalityPMID:23166349
SPAC1D4.01human C9orf78 ortholog Negative GeneticPMID:22681890
res2MBF transcription factor complex subunit Res2 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
hrq1RecQ type DNA helicase Hrq1 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC4D7.07csequence orphan Negative GeneticPMID:22681890
wis2cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
SPCC594.06cvacuolar SNARE Vam7 (predicted) Negative GeneticPMID:22681890
vht1vitamin H transporter Vth1 Negative GeneticPMID:22681890
SPAC323.03csequence orphan Positive GeneticPMID:18818364
mod21gamma tubulin complex subunit Mod21 Negative GeneticPMID:18818364
swc5Swr1 complex subunit Swc5 Negative GeneticPMID:18818364
bst1GPI inositol deacylase Bst1 (predicted) Negative GeneticPMID:22681890
rpl300160S ribosomal protein L30 (predicted) Negative GeneticPMID:22681890
swc2Swr1 complex complex subunit Swc2 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC70.04csequence orphan Negative GeneticPMID:22681890
idh2isocitrate dehydrogenase (NAD+) subunit 2 Positive GeneticPMID:22681890
fft3fun thirty related protein Fft3 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:18818364
swd1Set1C complex subunit Swd1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC227.06Rab GTPase binding (predicted) Negative GeneticPMID:22681890
ura1carbamoyl-phosphate synthase (glutamine hydrolyzing), aspartate carbamoyltransferase Ura1 Positive GeneticPMID:22681890
pof12F-box protein Pof12 Negative GeneticPMID:22681890
hos2histone deacetylase (class I) Hos2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
mpc1mitochondrial pyruvate transmembrane transporter subunit Mpc1 Negative GeneticPMID:22681890
rps00140S ribosomal protein S0A (p40) Negative GeneticPMID:22681890
mre11Mre11 nuclease Negative GeneticPMID:18818364
cdt2WD repeat protein Cdt2 Negative GeneticPMID:22681890
SPBC1604.03cconserved fungal protein Positive GeneticPMID:22681890
ryh1GTPase Ryh1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
SPCC285.04transthyretin (predicted) Positive GeneticPMID:22681890
SPCC550.08N-acetyltransferase (predicted) Negative GeneticPMID:22681890
SPAC22A12.14cBSD domain protein, unknown biological role Negative GeneticPMID:22681890
SPBC18A7.02cseven transmembrane receptor-like protein (predicted) Positive GeneticPMID:22681890
SPCC18.17c26S proteasome non-ATPase regulatory subunit (predicted) Negative GeneticPMID:22681890
eme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:18818364
rps40140S ribosomal protein S4 (predicted) Negative GeneticPMID:22681890
dcr1dicer Negative GeneticPMID:18818364
SPCC1393.08transcription factor, zf-GATA type (predicted) Negative GeneticPMID:22681890
SPBPB2B2.09c2-dehydropantoate 2-reductase (predicted) Negative GeneticPMID:22681890
SPAC2F3.11exopolyphosphatase (predicted) Negative GeneticPMID:22681890
SPBC1703.09sequence orphan Positive GeneticPMID:22681890
elp5elongator complex subunit Elp5 (predicted) Negative GeneticPMID:18818364
mpd2GYF domain protein Negative GeneticPMID:22681890
mdm31mitochondrial inner membrane protein Mdm31 (predicted) Negative GeneticPMID:22681890
SPCC550.11karyopherin (predicted) Negative GeneticPMID:22681890
snz1pyridoxine biosynthesis protein Negative GeneticPMID:22681890
tea2kinesin-like protein Tea2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC613.03conserved fungal protein Negative GeneticPMID:22681890
SPAC637.06alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
prz1calcineurin responsive transcription factor Prz1 Positive GeneticPMID:22681890
prw1Clr6 histone deacetylase complex subunit Prw1 Negative GeneticPMID:22681890
sre2membrane-tethered transcription factor (predicted) Negative GeneticPMID:21504829
sep1fork head transcription factor Sep1 Negative GeneticPMID:22681890
dlc1dynein light chain Dlc1 Negative GeneticPMID:22681890
pmc5mediator complex subunit Pmc5 Negative GeneticPMID:18818364
tip1CLIP170 family protein Tip1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
hip1hira protein, histone chaperone Hip1 Negative GeneticPMID:18818364
atp15F0-ATPase epsilon subunit (predicted) Negative GeneticPMID:22681890
clr3histone deacetylase (class II) Clr3 Positive GeneticPMID:18818364
mug154conserved fungal protein Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
vrp1verprolin Negative GeneticPMID:18818364
erd1Erd1 homolog (predicted) Negative GeneticPMID:22681890
rhp14XP-A family homolog Rhp14 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
pof3F-box protein Pof3 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
dad2DASH complex subunit Dad2 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
spf1Set1C PHD Finger protein Spf1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
pnk1DNA kinase/phosphatase Pnk1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
reb1RNA polymerase I transcription termination factor Reb1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
rsc58RSC complex subunit Rsc58 Positive GeneticPMID:22681890
rad2514-3-3 protein Rad25 Positive GeneticPMID:18818364
pof13F-box protein Pof13 Negative GeneticPMID:22681890
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
SPBC29A3.09cAAA family ATPase Gcn20 (predicted) Negative GeneticPMID:22681890
pzh1serine/threonine protein phosphatase Pzh1 Negative GeneticPMID:22681890
swc3Swr1 complex subunit Swc3 Negative GeneticPMID:18818364
met16phosphoadenosine phosphosulfate reductase Positive GeneticPMID:22681890
SPBC36B7.08cnucleosome assembly protein (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
mug81ATP-dependent RNA helicase Slh1 (predicted) Negative GeneticPMID:18818364
SPAPB2B4.04cvacuolar calcium transporting P-type ATPase P2 type, Pmc1 Negative GeneticPMID:22681890
srp1SR family protein, human SRFS2 ortholog Srp1 Negative GeneticPMID:22681890
psl1cyclin pho85 family (predicted) Negative GeneticPMID:22681890
SPAC3A11.13prefoldin subunit 6 (predicted) Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
SPAC12B10.01cubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:18818364
swd3WD repeat protein Swd3 Negative GeneticPMID:18818364
ctf18RFC-like complex subunit Ctf18 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
dad3DASH complex subunit Dad3 Positive GeneticPMID:22681890
rsc1RSC complex subunit Rsc1 Negative GeneticPMID:18818364
spo12Spo12 family protein Negative GeneticPMID:18818364
asp1inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted) Negative GeneticPMID:22681890
SPBC1348.02S. pombe specific 5Tm protein family Positive GeneticPMID:22681890
rpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
klp5kinesin-like protein Klp5 Synthetic LethalityPMID:16079915
peg1CLASP family microtubule-associated protein Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC9E9.04bcap family homolog (predicted) Negative GeneticPMID:22681890
rps120140S ribosomal protein S12 (predicted) Negative GeneticPMID:22681890
arf6ADP-ribosylation factor, Arf family Arf6 Negative GeneticPMID:22681890
SPCC553.05cwtf element Wtf6 Positive GeneticPMID:22681890
nup131nucleoporin Nup131 Positive GeneticPMID:18818364
atp2F1-ATPase beta subunit Atp2 Negative GeneticPMID:22681890
rpl160160S ribosomal protein L13/L16 (predicted) Negative GeneticPMID:18818364
mca1transcription factor, zf-fungal binuclear cluster type (predicted) Positive GeneticPMID:22681890
tea3cell end marker Tea3 Negative GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Negative GeneticPMID:22681890
tma23ribosome biogenesis protein Tma23 (predicted) Negative GeneticPMID:18818364
pnn1pinin ortholog, involved in splicing Pnn1 (predicted) Positive GeneticPMID:22681890
SPAC23A1.07ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:18818364
not2CCR4-Not complex subunit Not2 (predicted) Negative GeneticPMID:18818364
vps902guanyl-nucleotide exchange factor Vps902 (predicted) Positive GeneticPMID:22681890
SPAC1093.03inositol polyphosphate phosphatase (predicted) Positive GeneticPMID:18818364
rpl2260S ribosomal protein L22 (predicted) Negative GeneticPMID:22681890
kap113karyopherin Kap113 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPBC13E7.03cRNA hairpin binding protein (predicted) Negative GeneticPMID:22681890
SPBC215.06chuman LYAR homolog Positive GeneticPMID:22681890
raf1Rik1-associated factor Raf1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPBC4B4.04translation initiation factor eIF2A (predicted) Negative GeneticPMID:22681890
hst2Sir2 family histone deacetylase Hst2 Positive GeneticPMID:18818364
gyp51GTPase activating protein Gyp51 (predicted) Positive GeneticPMID:22681890
SPAC24B11.12cP-type ATPase (predicted) Negative GeneticPMID:22681890
msa1RNA-binding protein Msa1 Positive GeneticPMID:22681890
cgs2cAMP-specific phosphodiesterase Cgs2 Positive GeneticPMID:22681890
SPBP8B7.10cU3 snoRNP-associated protein Utp16 (predicted) Negative GeneticPMID:18818364
SPAC6C3.06cP-type ATPase, calcium transporting (predicted) Positive GeneticPMID:22681890
SPAC222.08cglutamine aminotransferase subunit (predicted) Negative GeneticPMID:22681890
crb2DNA repair protein Rad9 homolog, Rhp9 Positive GeneticPMID:22681890
spc19DASH complex subunit Spc19 Positive GeneticPMID:22681890
csn71COP9/signalosome complex subunit 7a (predicted) Negative GeneticPMID:22681890
SPAC6G9.01cconserved protein Positive GeneticPMID:22681890
hhf1histone H4 h4.1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
rad51RecA family recombinase Rad51/Rhp51 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
cbp1CENP-B homolog Negative GeneticPMID:18818364
SPCC548.05cubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC144.05ATP-dependent DNA helicase (predicted) Positive GeneticPMID:22681890
cip2RNA-binding protein Cip2 Negative GeneticPMID:22681890
SPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:18818364
rps40340S ribosomal protein S4 (predicted) Negative GeneticPMID:22681890
liz1pantothenate transporter Liz1 Negative GeneticPMID:22681890
ibp1Cdc25 family phosphatase Ibp1 Positive GeneticPMID:22681890
mal3EB1 family Mal3 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
csn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
dad4DASH complex subunit Dad4 Positive GeneticPMID:22681890
rrp1ATP-dependent DNA helicase (predicted) Negative GeneticPMID:22681890
mid1medial ring protein Mid1 Negative GeneticPMID:22681890
puf3RNA-binding protein Puf3 (predicted) Negative GeneticPMID:18818364
dam1DASH complex subunit Dam1 Positive GeneticPMID:22681890
ash2Ash2-trithorax family protein Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
set1histone lysine methyltransferase Set1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
mph1dual specificity protein kinase Mph1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCP20C8.02cS. pombe specific UPF0321 family protein 1 Positive GeneticPMID:22681890
dim1U4/U6 x U5 tri-snRNP complex subunit Dim1 Negative GeneticPMID:22681890
alp16gamma tubulin complex subunit Alp16 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPBC16C6.05mitochondrial translation initiation factor (predicted) Negative GeneticPMID:18818364
SPAC10F6.04RCC domain protein Ats1 (predicted) Positive GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
mrpl39mitochondrial ribosomal protein subunit L39 (predicted) Negative GeneticPMID:22681890
ppk16serine/threonine protein kinase Ppk16 (predicted) Negative GeneticPMID:18818364
mis6inner centromere protein, CENP-I ortholog Mis6 Synthetic LethalityPMID:16079915
aca1L-azetidine-2-carboxylic acid acetyltransferase Aca1 Positive GeneticPMID:22681890
eso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
dcd1deoxycytidylate deaminase (predicted) Negative GeneticPMID:22681890
sst6ESCRT I complex subunit Vps23 Negative GeneticPMID:22681890
pmp1dual-specificity MAP kinase phosphatase Pmp1 Negative GeneticPMID:18818364
pgt1glutathione transporter Pgt1 Positive GeneticPMID:22681890
atp10F1-F0 ATPase assembly protein (predicted) Negative GeneticPMID:22681890
mad2spindle checkpoint protein Mad2 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAP14E8.02FHA domain protein Tos4 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC1620.08succinate-CoA ligase beta subunit (predicted) Positive GeneticPMID:22681890
rtf2replication termination factor Rtf2 Negative GeneticPMID:22681890
rad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
SPBC839.03cneddylation protein Dcn1 (predicted) Negative GeneticPMID:18818364
SPAC9E9.09caldehyde dehydrogenase (predicted) Negative GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
SPBC13E7.08cRNA polymerase II associated Paf1 complex (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
rnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ies2Ino80 complex subunit Ies2 Negative GeneticPMID:22681890
pom1DYRK family protein kinase Pom1 Negative GeneticPMID:18818364
fta6Sim4 and Mal2 associated (4 and 2 associated) protein 6 Negative GeneticPMID:22681890
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
slx1structure-specific endonuclease catalytic subunit Positive GeneticPMID:18818364
trm112protein and tRNA methyltransferase regulatory subunit Trm112 (predicted) Negative GeneticPMID:22681890
msd1mitotic-spindle disanchored Msd1 Negative GeneticPMID:22681890
wtf15wtf element Wtf15 Negative GeneticPMID:22681890
med20mediator complex subunit Med20 Negative GeneticPMID:18818364
fkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
SPCC1620.12cGTPase activating protein (predicted) Negative GeneticPMID:22681890
SPBC1778.09GTPase activating protein (predicted) Positive GeneticPMID:22681890
amt1ammonium transporter Amt1 Positive GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
sec74guanyl-nucleotide exchange factor Sec74 (predicted) Positive GeneticPMID:22681890
lys2homoaconitate hydratase Lys2 Negative GeneticPMID:22681890
SPAC17H9.04cRNA-binding protein Positive GeneticPMID:22681890
pnu1mitochondrial endodeoxyribonuclease Pnu1 Negative GeneticPMID:22681890
rlp1RecA family ATPase Rlp1 Positive GeneticPMID:22681890
apc10anaphase-promoting complex subunit Apc10 Negative GeneticPMID:22681890
SPAC732.02cfructose-2,6-bisphosphate 2-phosphatase activity (predicted) Positive GeneticPMID:22681890
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:18818364
scs7sphingosine hydroxylase Scs7 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
klp6kinesin-like protein Klp6 Synthetic LethalityPMID:16079915
Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
rga8Rho-type GTPase activating protein Rga8 Negative GeneticPMID:22681890
mal2kinetochore protein, CENP-O ortholog Mal2 Synthetic LethalityPMID:16079915
SPBC29A10.16ccytochrome b5 (predicted) Negative GeneticPMID:22681890
snt2Lid2 complex subunit Snt2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC736.07cunconventional prefoldin involved in translation initiation (predicted) Negative GeneticPMID:22681890
gcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Positive GeneticPMID:18818364
SPCC1223.01ubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:18818364
ulp2SUMO deconjugating cysteine peptidase Ulp2 (predicted) Negative GeneticPMID:22681890
nrc1bromodomain protein (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
sgf29SAGA complex subunit Sgf29 Negative GeneticPMID:18818364
mms1E3 ubiquitin ligase complex subunit Mms1 (predicted) Negative GeneticPMID:22681890
SPAPB1E7.11csequence orphan Negative GeneticPMID:22681890
mad3mitotic spindle checkpoint protein Mad3 Negative GeneticPMID:22681890
rpt419S proteasome regulatory subunit Rpt4 (predicted) Negative GeneticPMID:22681890
ufd2ubiquitin-protein ligase E4 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
arp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
msc1multi-copy suppressor of Chk1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
sat1Golgi membrane exchange factor subunit Sat1 (predicted) Negative GeneticPMID:18818364
rik1silencing protein Rik1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
yaf9YEATS family histone acetyltransferase subunit Yaf9 Negative GeneticPMID:18818364
gma12alpha-1,2-galactosyltransferase Gma12 Negative GeneticPMID:22681890
rnh201ribonuclease H2 complex subunit Rnh201 (predicted) Positive GeneticPMID:22681890
hrp1ATP-dependent DNA helicase Hrp1 Negative GeneticPMID:18818364
hip4histone promoter control protein Hip4 Negative GeneticPMID:18818364
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
dad3DASH complex subunit Dad3 Affinity Capture-MSPMID:16079914
duo1DASH complex subunit Duo1 Affinity Capture-MSPMID:16079914
dam1DASH complex subunit Dam1 Affinity Capture-WesternPMID:22375062
Affinity Capture-MSPMID:16079914
dad2DASH complex subunit Dad2 Affinity Capture-MSPMID:16079914
dad5DASH complex subunit Dad5 Affinity Capture-MSPMID:16079914
spc34DASH complex subunit Spc34 Affinity Capture-MSPMID:16079914
dad1DASH complex subunit Dad1 Affinity Capture-MSPMID:16079914
Contact Curators
External References
Database Identifier Description
NBRP SPBC27.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC27.02c Retrieval of eukaryotic orthologs
BioGrid SPBC27.02c BioGRID Interaction Datasets
Bähler Lab SPBC27.02c Cell Cycle Expression Profile
Bähler Lab SPBC27.02c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC27.02c Pheromone response/mating expression profiles
Bähler Lab SPBC27.02c Environmental stress expression profiles
Bähler Lab SPBC27.02c Bähler Lab Transcriptome Viewer
Cyclebase SPBC27.02c Cell Cycle Data
PInt SPBC27.02c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC27.02c Entrez Gene
SPD / RIKEN16/16B11Orfeome Localization Data
EntrezGene2540498DASH complex subunit Ask1
Uniprot_genenameASK1
WikiGene2540498DASH complex subunit Ask1
UniProtKB/SwissProtQ9P6S5DASH complex subunit ask1
ModBaseQ9P6S5Database of comparative protein structure models
Pfam Protein DomainsQ9P6S5Pfam Domain Arrangement
RefSeq PeptideNP_595657DASH complex subunit Ask1
RefSeq mRNANM_001021551972h- DASH complex subunit Ask1 (ask1), mRNA
European Nucleotide ArchiveBAA12199ENA Protein Mapping
European Nucleotide ArchiveCAB89002ENA Protein Mapping
SPD / RIKEN16/16B11Orfeome Localization Data

Literature for ask1
Contact Curators

Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013