atf1 (SPBC29B5.01)


Gene Standard Nameatf1 Characterisation Statuspublished
Systematic IDSPBC29B5.01 Feature Typeprotein coding
Synonymsgad7, mts1, SPNCRNA.353, SPNG1409, sss1 Name DescriptionG1 Arrest Defective,
M Twenty Six binding protein
Producttranscription factor, Atf-CREB family Atf1 Product Size566aa, 59.71 kDa
Genomic Location Chromosome II, 1546194-1549862 (3669nt); CDS:1547661-1549361 (1701nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
double-stranded DNA binding161
Annotation ExtensionEvidenceWith/FromReference
protein binding887
Annotation ExtensionEvidenceWith/FromReference
recombination hotspot binding2
Annotation ExtensionEvidenceWith/FromReference
RNA binding588
Annotation ExtensionEvidenceWith/FromReference
RNA polymerase II core promoter proximal region sequence-specific DNA binding92
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding31
GO Biological Process
Term NameCount
activation of reciprocal meiotic recombination1
Annotation ExtensionEvidenceWith/FromReference
fungal-type cell wall organization or biogenesis96
Annotation ExtensionEvidenceWith/FromReference
mitotic G1 cell cycle arrest in response to nitrogen starvation11
Annotation ExtensionEvidenceWith/FromReference
negative regulation of antisense RNA transcription1
Annotation ExtensionEvidenceWith/FromReference
negative regulation of reciprocal meiotic recombination3
Annotation ExtensionEvidenceWith/FromReference
negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress2
Annotation ExtensionEvidenceWith/FromReference
nucleosome positioning7
Annotation ExtensionEvidenceWith/FromReference
osmosensory signaling pathway10
Annotation ExtensionEvidenceWith/FromReference
positive regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation2
Annotation ExtensionEvidenceWith/FromReference
positive regulation of transcription from RNA polymerase II promoter in response to maltose2
Annotation ExtensionEvidenceWith/FromReference
protein localization to nucleus36
Annotation ExtensionEvidenceWith/FromReference
reciprocal meiotic recombination45
Annotation ExtensionEvidenceWith/FromReference
regulation of cAMP-mediated signaling8
Annotation ExtensionEvidenceWith/FromReference
stress-activated MAPK cascade13
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
decreased cell population growth at low temperaturegad7::ura495
atf1Δ
decreased cell population growth on maltose carbon sourceatf1Δ3
decreased conjugation frequencyatf1Δ52
gad7::ura4
decreased frequency of meiosisatf1-/atf1- (homozygous diploid)14
decreased mating efficiencyatf1Δ275
gad7::ura4
decreased sporulation frequencygad7-/gad7- diploid103
inviable vegetative cell populationatf1+1455
loss of viability in stationary phaseatf1Δ61
normal cell population growth at high temperatureatf1Δ69
normal growth on anisomycinatf1Δ2
normal growth on cadmiumatf1Δ8
normal growth on cisplatinatf1Δ39
normal growth on cycloheximideatf1Δ12
normal growth on diamideatf1Δ5
normal growth on glucose carbon sourceatf1+294
gad7::ura4
atf1Δ
normal growth on methylglyoxalatf1Δ1
normal growth on staurosporineatf1Δ8
normal growth on tert-butyl hydroperoxideatf1Δ2
normal vegetative cell population growthatf1Δ813
normal viability following cellular response to methyl methanesulfonateatf1Δ1
normal viability following cellular response to UVatf1Δ7
normal viability in stationary phaseatf1Δ33
normal viability in stationary phase during nitrogen limitationatf1Δ2
resistance to cadmiumatf1Δ13
resistance to clotrimazoleatf1Δ19
resistance to heat shock during nitrogen starvationgad7::ura42
resistance to miconazoleatf1Δ9
resistance to tacrolimus during salt stressatf1Δ8
sensitive to caffeine during vegetative growthatf1Δ110
sensitive to cell wall-degrading enzymesatf1Δ47
sensitive to high osmolarityatf1Δ17
sensitive to hydrogen peroxideatf1Δ155
sensitive to hygromycin Batf1Δ16
sensitive to micafunginatf1Δ119
sensitive to salt stressgad7::ura499
atf1Δ
sensitive to sorbitolatf1Δ13
slow vegetative cell population growthgad7::ura4367
viable vegetative cell populationatf1Δ3850

Cell Phenotype

Term NameGenotypesCount
abnormal cell cycle arrest in mitotic G2 phase during nitrogen starvationgad7::ura49
atf1Δ
abnormal nucleosome positioning at stress response genesatf1Δ1
abnormal regulation of translation in response to osmotic stressatf1Δ2
abolished protein localization to nucleus during cellular response to salt stress4
affects localization of sty1atf1Δ
abolished RNA polymerase II core promoter proximal region sequence-specific DNA binding9
affecting pcr1 and SO:0001843gad7::ura4
abolished transcription from CRE promoteratf1Δ1
abolished transcription from CRE promoter during cellular response to miconazoleatf1Δ1
decreased cell cycle arrest in mitotic G1 phase in response to nitrogen starvationgad7::ura416
atf1Δ
decreased glutathione disulfide oxidoreductase activityatf1Δ4
decreased meiotic recombination at M26 siteatf1Δ2
atf1+
decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen starvation2
affecting rpb1atf1Δ
decreased protein level during cellular response to hydrogen peroxide11
affecting ctt1atf1Δ
decreased protein level during cellular response to nitrogen starvation12
affecting mei2atf1Δ
decreased protein level during cellular response to salt stress3
affecting ish1atf1Δ
decreased protein level during vegetative growthatf1Δ153
affecting grx1atf1Δ
decreased protein localization to M26 site2
affects localization of med7atf1Δ
decreased RNA level during cellular response to glucose stimulus4
affecting mae2atf1 mutant
decreased RNA level during cellular response to heat7
affecting pyp2atf1Δ
affecting pmp3atf1Δ
decreased RNA level during cellular response to hydrogen peroxide23
affecting pyp2atf1Δ
affecting tps1atf1Δ
affecting gst3atf1Δ
affecting sod1atf1Δ
affecting hsp9atf1-bZIP (1-394)
affecting gpd1atf1-bZIP (1-394)
affecting ntp1atf1Δ
affecting pmp3atf1Δ
affecting ecl1atf1Δ
decreased RNA level during cellular response to hypoxia7
affecting mae2atf1 mutant
decreased RNA level during cellular response to menadione4
affecting sod2atf1Δ
decreased RNA level during cellular response to non-ionic osmotic stress3
affecting pyp2atf1Δ
affecting pmp3atf1Δ
affecting cta3atf1Δ
affecting ctt1atf1Δ
decreased RNA level during cellular response to salt stress14
affecting pyp2atf1Δ
affecting ptc3atf1Δ
affecting tps1atf1Δ
affecting gpd1atf1Δ
affecting gpx1atf1Δ
affecting ntp1atf1Δ
affecting cta3atf1Δ
affecting ptc1atf1Δ
affecting ctt1atf1Δ
decreased RNA level during cellular response to UV11
affecting pyp2atf1Δ
affecting ctt1atf1Δ
decreased RNA level during mitotic G2 phase1
affecting cdc13atf1Δ
decreased RNA level during nitrogen starvation43
affecting ste11atf1Δ
affecting ste11gad7::ura4
decreased RNA level during vegetative growth200
affecting sty1atf1Δ
affecting ptc3atf1Δ
affecting its8atf1Δ
affecting ptc1atf1Δ
decreased transcription during vegetative growth49
affecting agl1atf1Δ
affecting fbp1atf1Δ
elongated cell during nitrogen starvationgad7::ura423
increased duration of protein phosphorylation during cellular response to salt stress4
affecting sty1atf1Δ
increased level of cell cycle regulated gene mRNA during vegetative growthatf1+1
increased level of transport gene mRNA during vegetative growthatf1+10
increased nucleosome occupancy at CRE siteatf1Δ1
increased protein level during vegetative growth114
affecting cdc13atf1+
increased protein localization to nucleus during vegetative growth23
affects localization of cdc2atf1+
increased protein phosphorylation during vegetative growth65
affecting plo1atf1Δ
increased RNA level during vegetative growth342
affecting ste11atf1Δ
affecting cdc13atf1+
affecting bfr1atf1Δ
increased RNA level in stationary phase4
affecting sod1atf1Δ
increased stress response gene antisense RNA levelatf1Δ1
normal alpha,alpha-trehalase activity increase during cellular response to oxidative stressatf1Δ1
normal alpha,alpha-trehalase activity increase during cellular response to salt stressatf1Δ4
normal cellular response to arsenicatf1Δ2
normal cellular trehalose level during cellular response to oxidative stressatf1Δ2
normal cellular trehalose level during cellular response to salt stressatf1Δ3
normal meiotic recombination at M26 siteatf1-11M (S2A, S4A, T77A, S140A, S152A, S172A, T204I, T216I, S226A, T249I, S438A)2
normal nucleosome positioning at stress response genesatf1-bZIP (1-394)1
normal protein level during vegetative growth91
affecting mei2atf1Δ
affecting fbp1atf1Δ
affecting grx3atf1Δ
normal protein tyrosine phosphorylation during cellular response to osmotic stress4
affecting sty1atf1Δ
normal RNA level during cellular response to heat5
affecting sod2atf1Δ
normal RNA level during cellular response to hydrogen peroxide9
affecting ntp1atf1Δ
affecting tpx1atf1Δ
normal RNA level during cellular response to menadione4
affecting sod1atf1Δ
normal RNA level during cellular response to salt stress8
affecting sod2atf1Δ
normal RNA level during cellular response to UV9
affecting uvi15atf1Δ
normal RNA level during nitrogen starvation8
affecting ecl1atf1Δ
normal RNA level during vegetative growth133
affecting gst3atf1Δ
affecting ctt1atf1Δ
premature mitosisatf1+5
protein absent from cell during vegetative growth10
affecting ish1atf1Δ
RNA absent from cell during cellular response to hydrogen peroxide3
affecting gpx1atf1Δ
RNA absent from cell during cellular response to salt stress5
affecting pyp2atf1Δ
affecting gpd1atf1Δ
RNA absent from cell during vegetative growth21
affecting gpd1atf1Δ
affecting gpx1atf1Δ
single cell division prior to G0 entryatf1Δ2
sterileatf1Δ61
viable small vegetative cellatf1+54
viable thin, elongated vegetative cellatf1Δ2
viable vegetative cell with normal cell morphologyatf1Δ3102

FYPO Multi-allele Phenotypes

Population Phenotype

Term NameGenotypes
inviable vegetative cell populationatf1Δ, pat1-114
loss of viability in stationary phaseatf1Δ, sty1Δ
normal growth on glucose carbon sourcepap1Δ, atf1Δ
sensitive to hydrogen peroxidepap1Δ, atf1Δ
sensitive to salt stresstup12Δ, atf1Δ, tup11Δ
viable vegetative cell populationatf1Δ, cdc25Δ
pat1-114, atf1Δ
atf1Δ, pat1-114

Cell Phenotype

Term NameGenotypes
decreased cellular glutathione level during vegetative growthatf1Δ, sty1Δ
decreased histone H3-K9 dimethylation at silent mating-type cassetteatf1Δ, dcr1Δ
atf1Δ, dsh1Δ
decreased protein level during cellular response to nitrosative stress
affecting gsa1atf1Δ, sty1Δ
decreased protein level during vegetative growth
affecting gsa1atf1Δ, sty1Δ
decreased RNA level during cellular response to heat
affecting grx2atf1Δ, pap1Δ
affecting grx1atf1Δ, pap1Δ
decreased RNA level during cellular response to hydrogen peroxide
affecting grx2atf1Δ, pap1Δ
affecting grx1atf1Δ, pap1Δ
decreased RNA level during cellular response to salt stress
affecting cta3tup12Δ, atf1Δ, tup11Δ
increased RNA level during vegetative growth
affecting cta3tup12Δ, atf1Δ, tup11Δ
inviable elongated aseptate cellatf1+, cdc2-33 (A177T)
atf1+, cdc13-117
cdc25-22 (C532Y), atf1-bZIP (1-394)
mitotic catastrophe with cutatf1+, cdc25-22 (C532Y)
mitotic G2/M transition delayatf1Δ, cdc25-22 (C532Y)
normal nucleosome positioning at stress response genesctt1.G4BS (ATGACGT-435CGGAAGACTCTCCTCCG), G4-Atf1 (Atf1 amino acids 1-395 fused to budding yeast Gal4p DNA binding domain)
gpd1.G4BS (TTACGTCA-329CGGAAGACTCTCCTCCG), G4-Atf1 (Atf1 amino acids 1-395 fused to budding yeast Gal4p DNA binding domain)
premature mitotic G2/M transitionwee1-50, atf1+
Target Of
OntologyRelationshipGeneProduct
FYPO affected by mutation in cgs1 cAMP-dependent protein kinase regulatory subunit Cgs1
FYPO affected by mutation in csx1 RNA-binding protein Csx1
FYPO affected by mutation in ctu2 cytosolic thiouridylase subunit Ctu2
FYPO affected by mutation in elp3 elongator complex subunit Elp3 (predicted)
FYPO affected by mutation in lkh1 dual specificity protein kinase Lkh1
FYPO affected by mutation in mcs4 response regulator Mcs4
FYPO affected by mutation in moe1 translation initiation factor eIF3d Moe1
FYPO affected by mutation in pap1 transcription factor Pap1/Caf3
FYPO affected by mutation in pcr1 transcription factor Pcr1
FYPO affected by mutation in pek1 MAP kinase kinase Pek1
FYPO affected by mutation in pka1 cAMP-dependent protein kinase catalytic subunit Pka1
FYPO affected by mutation in pmk1 MAP kinase Pmk1
FYPO affected by mutation in sty1 MAP kinase Sty1
FYPO affected by mutation in trm112 protein and tRNA methyltransferase regulatory subunit Trm112 (predicted)
FYPO affected by mutation in trm9 tRNA (uridine) methyltransferase Trm9 (predicted)
FYPO affected by mutation in upf1 ATP-dependent RNA helicase Upf1
FYPO affected by mutation in win1 MAP kinase kinase kinase Win1
FYPO affected by mutation in wis1 MAP kinase kinase Wis1
FYPO affected by mutation in wis4 MAP kinase kinase kinase Wis4
FYPO localization affected by mutation in pcr1 transcription factor Pcr1
GO binds csx1 RNA-binding protein Csx1
GO regulated by csx1 RNA-binding protein Csx1
GO regulated by pmk1 MAP kinase Pmk1
GO regulated by sty1 MAP kinase Sty1
GO substrate of pmk1 MAP kinase Pmk1
GO substrate of srk1 MAPK-activated protein kinase Srk1
GO substrate of sty1 MAP kinase Sty1
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons1546194..1546464, 1547320..1549862
Intron1546465..1547319
mRNA1546194..1549862
5' UTR1546194..1546464, 1547320..1547660PMID:21511999
CDS1547661..1549361
3' UTR1549362..1549862PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF11786 Pfam IPR021755 Transcription factor Aft1, HRA domain 153 233 1
PF11785 Pfam IPR020956 Transcription factor Aft1, osmotic stress domain 77 101 1
PF00170 Pfam IPR004827 Basic-leucine zipper domain 474 530 5
SM00338 SMART IPR004827 Basic-leucine zipper domain 470 534 5
PS50217 Prosite Profiles IPR004827 Basic-leucine zipper domain 472 535 6
PTHR19304:SF5 HMMPANTHER 84 359 1
PTHR19304 HMMPANTHER 84 359 5
PTHR19304:SF5 HMMPANTHER 424 542 1
PTHR19304 HMMPANTHER 424 542 5
1.20.5.170 Gene3D Peptide chain release factor eRF1/aRF1 474 535 7
SSF57959 SuperFamily 474 534 6
Coil ncoils Predicted coiled-coil protein (DUF2205) 497 531 1055

View domain organization at Pfam

Term IDTerm NameReferenceCount
PBO:0000545bZIP (basic leucine zipper) transcription factor familyPMID:8824587Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000545
PBO:0002433Atf-CREB subfamilyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0002433

Protein Properties

Ave. residue weight 105.50 Da
Charge -2.50
Codon Adaptation Index 0.41
Isoelectric point 5.75
Molecular weight 59.71 kDa
Number of residues 566
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS115, S117 2289
Annotation ExtensionEvidenceResidueReference
IDA S117 PMID:25720772
IDA S115 PMID:25720772
phosphorylated residue 2511
added by sty1, added during cellular response to salt stress
added by sty1, added during cellular response to heat
added by sty1, added during cellular response to hydrogen peroxide
added during single-celled organism vegetative growth phase
removed during cellular response to nitrogen starvation
sumoylated lysine 174
Annotation ExtensionEvidenceResidueReference
IDA PMID:26404184
O-phosphorylated residue 2457
added by sty1, added during cellular response to heat
in presence of micafungin
Annotation ExtensionEvidenceResidueReference
added by sty1
added during cellular response to heat
IDA PMID:9450957
in presence of micafungin IDA PMID:17881729
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
protein levelincreased during GO:0006995reporter gene assay evidencePMID:19940942
increased during GO:0071472immunofluorescence evidencePMID:9585506
increased during GO:0042149reporter gene assay evidencePMID:19940942
increased during GO:0071500reporter gene assay evidencePMID:19940942
present during GO:0072690Western blot evidencePMID:8824587
increased during GO:0070301Western blot evidencePMID:23874237
present during GO:0072690immunofluorescence evidencePMID:9585506
RNA levelincreased in presence of methyl methanesulfonate expression microarray evidencePMID:12529438
decreased during GO:1905308quantitative PCRPMID:26108447
increased during GO:0034599expression microarray evidencePMID:12529438
increased during GO:0070301Northern assay evidencePMID:23874237
present during GO:0072690quantitative PCRPMID:19940942
increased during GO:0071472Northern assay evidencePMID:8824587
increased in presence of cadmium sulfate expression microarray evidencePMID:12529438
present during GO:0072690Northern assay evidencePMID:23874237
increased during GO:0071500quantitative PCRPMID:19940942
increased during GO:0034605expression microarray evidencePMID:12529438
present during GO:0072690Northern assay evidencePMID:8824587
increased during GO:0070301quantitative PCRPMID:17612531
increased during GO:0006995quantitative PCRPMID:19940942
present during GO:0072690quantitative PCRPMID:8557039
increased during GO:0071470expression microarray evidencePMID:12529438
unchanged during GO:0006995quantitative PCRPMID:8557039

Quantitative Gene Expression

View graphical display of gene expression data for atf1 (SPBC29B5.01)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3577.25during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
6987.67during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
5during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
3during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Subunit Composition
DescriptionQualifierReferenceCount
homomeric(2) PMID:795884952
heteromeric(2) PMID:795884943
Misc
DescriptionQualifierReferenceCount
deletion mutant expression profiling PMID:18003976 PMID:1252943879
Pathway
DescriptionQualifierReferenceCount
links stress-activated MAPK (Sty1) pathway to cAMP-dependent protein kinase (Pka1) pathway PMID:154481373
Taxonomic Conservation
DescriptionQualifierReferenceCount
orthologs cannot be distinguished124
conserved in fungi4607
conserved in eukaryotes4517
conserved in eukaryotes only2502
Orthologs

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPBC29B5.01 into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
modifiessty1MAP kinase Sty1 Biochemical ActivityPMID:12383265
affinity capturespcr1transcription factor Pcr1 Affinity Capture-RNAPMID:22144913
affinity capturessty1MAP kinase Sty1 Affinity Capture-WesternPMID:8824587
affinity capturesclr6histone deacetylase (class I) Clr6 Affinity Capture-WesternPMID:15292231
affinity capturesclr3histone deacetylase (class II) Clr3 Affinity Capture-WesternPMID:15292231
affinity captured byswi6HP1 family chromodomain protein Swi6 Affinity Capture-WesternPMID:15292231
affinity captured byrhp23Rad23 homolog Rhp23 Affinity Capture-WesternPMID:11584278
affinity captured byfbh1DNA helicase I, ubiquitin ligase F-box adaptor Fbh1 Affinity Capture-WesternPMID:19836238
affinity captured byrpn1019S proteasome regulatory subunit Rpn10 Affinity Capture-WesternPMID:11584278
affinity captured bypka1cAMP-dependent protein kinase catalytic subunit Pka1 Affinity Capture-WesternPMID:23640764
affinity captured bydph1UBA domain protein Dph1 Affinity Capture-WesternPMID:11584278
affinity captured bycbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
affinity captured bycid12poly(A) polymerase Cid12 Affinity Capture-WesternPMID:26771498
interacts withpcr1transcription factor Pcr1 PCAPMID:26771498
binds DNA-binding domain construct withsty1MAP kinase Sty1 Two-hybridPMID:26771498
binds DNA-binding domain construct withpcr1transcription factor Pcr1 Two-hybridPMID:26771498
binds activation domain construct withcid12poly(A) polymerase Cid12 Two-hybridPMID:26771498
binds activation domain construct withatf1transcription factor, Atf-CREB family Atf1 Two-hybridPMID:26771498
modified bysty1MAP kinase Sty1 Biochemical ActivityPMID:8824588
modified bypka1cAMP-dependent protein kinase catalytic subunit Pka1 Biochemical ActivityPMID:23640764
modified bypmk1MAP kinase Pmk1 Biochemical ActivityPMID:17881729
co-fractionates withpcr1transcription factor Pcr1 Co-fractionationPMID:7958849
Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPBC29B5.01 into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
rescued bywee1M phase inhibitor protein kinase Wee1 Phenotypic SuppressionPMID:9135083
rescued byste11transcription factor Ste11 Phenotypic SuppressionPMID:11129048
rescued byecl1extender of the chronological lifespan protein Ecl1 Phenotypic SuppressionPMID:24696293
synthetic lethal withcgs2cAMP-specific phosphodiesterase Cgs2 Synthetic LethalityPMID:8557039
synthetic lethal withcgs1cAMP-dependent protein kinase regulatory subunit Cgs1 Synthetic LethalityPMID:8557039
synthetic lethal withubp6ubiquitin C-terminal hydrolase Ubp6 Synthetic LethalityPMID:15533439
synthetic lethal withcut1separase/separin Synthetic LethalityPMID:16861909
synthetic lethal withrpn1019S proteasome regulatory subunit Rpn10 Synthetic LethalityPMID:10809753
synthetic lethal withsck2serine/threonine protein kinase Sck2 Synthetic LethalityPMID:20453258
synthetic lethal withpap1transcription factor Pap1/Caf3 Synthetic LethalityPMID:15247218
synthetic growth defect withsty1MAP kinase Sty1 Synthetic Growth DefectPMID:20075862
synthetic growth defect withprr1transcription factor Prr1 Synthetic Growth DefectPMID:11179424
synthetic growth defect withcdc25M phase inducer tyrosine phosphatase Cdc25 Synthetic Growth DefectPMID:24728197
synthetic growth defect withuch2ubiquitin C-terminal hydrolase Uch2 Synthetic Growth DefectPMID:15533439
rescuescyr1adenylate cyclase Phenotypic SuppressionPMID:8557039
rescueswis1MAP kinase kinase Wis1 Phenotypic SuppressionPMID:15870269
rescuescdc25M phase inducer tyrosine phosphatase Cdc25 Phenotypic SuppressionPMID:24728197
rescuestup12transcriptional corepressor Tup12 Phenotypic SuppressionPMID:11238405
rescuessty1MAP kinase Sty1 Phenotypic SuppressionPMID:9154834
rescuestup11transcriptional corepressor Tup11 Phenotypic SuppressionPMID:11238405
synthetically rescuespat1serine/threonine protein kinase Ran1/Pat1 Synthetic RescuePMID:8557039
synthetically rescuessty1MAP kinase Sty1 Synthetic RescuePMID:9154834
synthetically rescuescdc13G2/M B-type cyclin Cdc13 Synthetic RescuePMID:24728197
synthetically rescuespap1transcription factor Pap1/Caf3 Synthetic RescuePMID:16087744
synthetically rescueswis1MAP kinase kinase Wis1 Synthetic RescuePMID:8824587
phenotype enhanced bydsh1RNAi protein, Dsh1 Phenotypic EnhancementPMID:22895252
phenotype enhanced bypap1transcription factor Pap1/Caf3 Phenotypic EnhancementPMID:15358115
phenotype enhanced bydcr1dicer Phenotypic EnhancementPMID:15218150
phenotype enhanced bypcr1transcription factor Pcr1 Phenotypic EnhancementPMID:18375616
phenotype enhanced bydeb1transcription factor Deb1/Rdp1 Phenotypic EnhancementPMID:15218150
phenotype enhanced byago1argonaute Phenotypic EnhancementPMID:15218150
enhances phenotype ofpap1transcription factor Pap1/Caf3 Phenotypic EnhancementPMID:9585505
enhances phenotype ofcdc25M phase inducer tyrosine phosphatase Cdc25 Phenotypic EnhancementPMID:24728197
enhances phenotype ofsty1MAP kinase Sty1 Phenotypic EnhancementPMID:20061379
rescued by overexpression ofzip1transcription factor Zip1 Dosage RescuePMID:10102365
rescued by overexpression ofatf31transcription factor Atf31 Dosage RescuePMID:10102365
rescued by overexpression ofpcr1transcription factor Pcr1 Dosage RescuePMID:10102365
rescued by overexpression ofatf21transcription factor, Atf-CREB family Atf21 Dosage RescuePMID:10102365
overexpression rescuespap1transcription factor Pap1/Caf3 Dosage RescuePMID:24521463
overexpression rescuessty1MAP kinase Sty1 Dosage RescuePMID:20061379
overexpression rescuesint6eIF3e subunit Int6 Dosage RescuePMID:20875427
synthetically rescued bycip2RNA-binding protein Cip2 Synthetic RescuePMID:16407405
synthetically rescued bycip1RNA-binding protein Cip1 Synthetic RescuePMID:16407405
overexpression causes growth defect towee1M phase inhibitor protein kinase Wee1 Dosage Growth DefectPMID:24728197
External References
Database Identifier Description
NBRP SPBC29B5.01 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC29B5.01 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC29B5.01 BioGRID Interaction Datasets
Expression Viewer SPBC29B5.01 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC29B5.01 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC29B5.01 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC29B5.01 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC29B5.01 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC29B5.01 Transcriptome Viewer (Bähler Lab)
GEO SPBC29B5.01 GEO profiles
PInt SPBC29B5.01 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC29B5.01 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC29B5.01 Fission yeast phenotypic data & analysis
Cyclebase SPBC29B5.01.1 Cell Cycle Data
SPD / RIKEN33/33C12Orfeome Localization Data
UniProtKB/SwissProtP52890Transcription factor atf1
ModBaseP52890Database of comparative protein structure models
STRINGP52890Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595652transcription factor, Atf-CREB family Atf1
European Nucleotide ArchiveAAA93260.1ENA Protein Mapping
European Nucleotide ArchiveAAB46990.1ENA Protein Mapping
European Nucleotide ArchiveBAA09817.1ENA Protein Mapping
European Nucleotide ArchiveBAA09841.1ENA Protein Mapping
European Nucleotide ArchiveBAA12194.1ENA Protein Mapping
European Nucleotide ArchiveCAC05510.1ENA Protein Mapping
UniParcUPI0000126228UniProt Archive
GEOGSE71820WT overexpression expression profiling

Literature for atf1

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Release Version: PomBase:30_61 - 12 Sep 2016