rpl802 (SPBC2F12.07c)


Gene Standard Namerpl802 Characterisation Statusbiological_role_inferred
Systematic IDSPBC2F12.07c Feature Typeprotein coding
Synonymsrpk37, rpk5b, rpl8-2 Name Description
Product60S ribosomal protein L8 (predicted) Product Size253aa, 27.10 kDa
Genomic Location Chromosome II, 1726632-1727577 (946nt); CDS:1726677-1727438 (762nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0019843rRNA bindingISMPFAM:PF00181GO_REF:000000156
GO:0003735structural constituent of ribosomeISOSGD:S000001280GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002181cytoplasmic translationNASGO_REF:0000051446
GO:0006412translationISOSGD:S000001280GO_REF:0000024599
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0022625cytosolic large ribosomal subunitISOSGD:S000001280GO_REF:000002482
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyrpl802ΔNullPMID:204732893751
Microscopyrpl802ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyrpl802ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
117266321727577
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00181 Pfam IPR022666 Ribosomal Proteins L2, RNA binding domain 15 89 4
PF03947 Pfam IPR022669 Ribosomal protein L2, C-terminal 96 228 4
PS00467 Prosite Patterns IPR022671 Ribosomal protein L2, conserved site 196 207 4
PTHR13691 HMMPANTHER IPR002171 Ribosomal protein L2 1 253 4
PTHR13691:SF4 HMMPANTHER 1 253 3
2.40.50.140 Gene3D IPR012340 Nucleic acid-binding, OB-fold 1 85 48
4.10.950.10 Gene3D IPR014726 Ribosomal protein L2, domain 3 169 243 4
2.30.30.30 Gene3D IPR014722 Ribosomal protein L2 domain 2 89 168 13
SSF50249 SuperFamily IPR012340 Nucleic acid-binding, OB-fold 2 96 57
SSF50104 SuperFamily IPR008991 Translation protein SH3-like domain 98 244 16
PIRSF002158 PIRSF IPR002171 Ribosomal protein L2 1 253 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 107.12 Da
Charge 29.50
Isoelectric point 11.45
Molecular weight 27.10 kDa
Number of residues 253
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
NDduring GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
38during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
4.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4599
conserved in eukaryotes4514
conserved in bacteria1002
conserved in metazoa3428
conserved in vertebrates3402
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
cid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
air1zinc knuckle TRAMP complex subunit Air1 Affinity Capture-MSPMID:20403971
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
External References
Database Identifier Description
NBRP SPBC2F12.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC2F12.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC2F12.07c BioGRID Interaction Datasets
Expression Viewer SPBC2F12.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC2F12.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC2F12.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC2F12.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC2F12.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC2F12.07c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC2F12.07c Cell Cycle Data
GEO SPBC2F12.07c GEO profiles
PInt SPBC2F12.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC2F12.07c Peptides identified in tandem mass spectrometry proteomics experiments
UniProtKB/SwissProtP0809360S ribosomal protein L2
ModBaseP08093Database of comparative protein structure models
STRINGP08093Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59570960S ribosomal protein L2
RefSeq mRNANM_001021606972h- 60S ribosomal protein L2 (rpl802), mRNA
European Nucleotide ArchiveBAA87149.1ENA Protein Mapping
European Nucleotide ArchiveCAA28710.1ENA Protein Mapping
European Nucleotide ArchiveCAA34428.1ENA Protein Mapping
European Nucleotide ArchiveCAA35971.1ENA Protein Mapping
European Nucleotide ArchiveCAA91960.1ENA Protein Mapping
European Nucleotide ArchiveCAB10155.1ENA Protein Mapping
European Nucleotide ArchiveCAB46697.1ENA Protein Mapping
UniParcUPI0000133ED3UniProt Archive

Literature for rpl802

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014