rpl802 (SPBC2F12.07c)


Gene Standard Namerpl802 Characterisation Statusbiological role inferred
Systematic IDSPBC2F12.07c Feature Typeprotein coding
Synonymsrpk37, rpk5b, rpl8-2 Name Description
Product60S ribosomal protein L8 (predicted) Product Size253aa, 27.10 kDa
Genomic Location Chromosome II, 1726632-1727577 (946nt); CDS:1726677-1727438 (762nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
rRNA binding57
Annotation ExtensionEvidenceWith/FromReference
structural constituent of ribosome257
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation469
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosolic large ribosomal subunit83
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
viable vegetative cell populationrpl802Δ3840

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologyrpl802Δ3100
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons1726632..1727577
mRNA1726632..1727577
5' UTR1726632..1726676PMID:21511999
CDS1726677..1727438
3' UTR1727439..1727577PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00181 Pfam IPR022666 Ribosomal Proteins L2, RNA binding domain 15 89 4
PF03947 Pfam IPR022669 Ribosomal protein L2, C-terminal 97 221 4
PS00467 Prosite Patterns IPR022671 Ribosomal protein L2, conserved site 196 207 4
PTHR13691:SF16 HMMPANTHER 1 253 3
PTHR13691 HMMPANTHER IPR002171 Ribosomal protein L2 1 253 4
2.30.30.30 Gene3D IPR014722 Ribosomal protein L2 domain 2 89 168 13
2.40.50.140 Gene3D IPR012340 Nucleic acid-binding, OB-fold 1 85 48
4.10.950.10 Gene3D IPR014726 Ribosomal protein L2, domain 3 169 243 4
SSF50249 SuperFamily IPR012340 Nucleic acid-binding, OB-fold 2 96 57
SSF50104 SuperFamily IPR008991 Translation protein SH3-like domain 98 244 16
PIRSF002158 PIRSF IPR002171 Ribosomal protein L2 1 251 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 107.12 Da
Charge 29.50
Codon Adaptation Index 0.77
Isoelectric point 11.45
Molecular weight 27.10 kDa
Number of residues 253
Modifications

Protein Modifications

Term NameResidueCount
ubiquitinylated lysineK144, K180 512
Annotation ExtensionEvidenceResidueReference
IDA PMID:26412298
mass spectrometry evidence K144 PMID:26412298
mass spectrometry evidence K180 PMID:26412298
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for rpl802 (SPBC2F12.07c)

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
38during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
4.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4606
conserved in eukaryotes4516
conserved in bacteria1001
conserved in metazoa3424
conserved in vertebrates3399
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPBC2F12.07c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byair1zinc knuckle TRAMP complex subunit Air1 Affinity Capture-MSPMID:20403971
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
affinity captured bycid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
External References
Database Identifier Description
NBRP SPBC2F12.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC2F12.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC2F12.07c BioGRID Interaction Datasets
Expression Viewer SPBC2F12.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC2F12.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC2F12.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC2F12.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC2F12.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC2F12.07c Transcriptome Viewer (Bähler Lab)
GEO SPBC2F12.07c GEO profiles
PInt SPBC2F12.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC2F12.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC2F12.07c Fission yeast phenotypic data & analysis
Cyclebase SPBC2F12.07c.1 Cell Cycle Data
UniProtKB/SwissProtP0CT7060S ribosomal protein L2-A
ModBaseP0CT70Database of comparative protein structure models
STRINGP0CT70Network display of known and predicted interactions and functional associations
UniProtKB/SwissProtP0CT7160S ribosomal protein L2-B
ModBaseP0CT71Database of comparative protein structure models
STRINGP0CT71Network display of known and predicted interactions and functional associations
UniProtKB/SwissProtP0CT7260S ribosomal protein L2-C
ModBaseP0CT72Database of comparative protein structure models
STRINGP0CT72Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59570960S ribosomal protein L2
RefSeq mRNANM_001021606972h- 60S ribosomal protein L2 (rpl802), mRNA

Literature for rpl802

Search: Europe PMC or PubMed

Release Version: PomBase:30_59 - 12 Apr 2016