SPBC2F12.12c

Synonyms ChromosomeII
Producthuman c19orf29 ortholog Gene Start1712841
Feature Typeprotein coding Gene End1714938
Name Description CDS Start1713103
Characterisation Statusconserved_unknown CDS End1714886

Ensembl Gene Location
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
117128411713228
217132751713526
317135821713674
417137211714173
517142571714938

Protein Feature Information

Protein Features

Ensembl protein image with mapped locations of structural domains
Feature ID Database Description Start End Score All Genes
PF09732 Pfam Cactin C-terminal domain 383 517 167.2 2
PF10312 Pfam Cactin, domain 54 240 164.3 1

Protein Properties

Ave. residue weight 117.72 Da
Charge 14.00
Isoelectric point 9.52
Molecular weight 60.86 kDa
Number of residues 517
Sequence

Fission Yeast Phenotype

Term IDDescriptionSourceAll Genes
FYPO:0000124viable
Temporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000124

Gene Ontology Annotations

Cellular Component
GO IDTermEvidenceWith/FromSourceAll Genes
GO:0005634nucleusIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005634
GO:0005739mitochondrionIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005739

Species Distribution

DescriptionSourceAll Genes
conserved in FungiTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000057
conserved in Eukaryotes onlyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000096
conserved in VertebratesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000095
conserved in EukaryotesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000058
predominantly uniformly single copy (one to one)Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000104
no apparent S. cerevisiae orthologTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000055
conserved in MetazoaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000094

Interactions

Genetic Interactions from BioGRID

Gene Feature Evidence Source
SPAC227.05prefoldin subunit 4 (predicted) Positive Genetic
tea2kinesin-like protein Tea2 Negative Genetic
cwf21complexed with Cdc5 protein Cwf21 Negative Genetic
usp103U1 snRNP-associated protein Usp103 (predicted) Negative Genetic
rad2FEN-1 endonuclease Rad2 Negative Genetic
sdc1Dpy-30 domain protein Sdc1 Negative Genetic
set6histone lysine methyltransferase Set6 (predicted) Negative Genetic
clr4histone H3 methyltransferase Clr4 Negative Genetic
rok1ATP-dependent RNA helicase Rok1 (predicted) Positive Genetic
iwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive Genetic
SPBC2A9.03WD40/YVTN repeat-like Negative Genetic
tip1CLIP170 family protein Tip1 Negative Genetic
hht1histone H3 h3.1 Negative Genetic
set1histone lysine methyltransferase Set1 Negative Genetic
dcc1Ctf18 RFC-like complex subunit Dcc1 Negative Genetic
mst2histone acetyltransferase Mst2 Negative Genetic
rap1telomere binding protein Rap1 Negative Genetic
hip1hira protein, histone chaperone Hip1 Negative Genetic
mph1dual specificity protein kinase Mph1 Negative Genetic
clr3histone deacetylase (class II) Clr3 Negative Genetic
mug154conserved fungal protein Negative Genetic
ago1argonaute Negative Genetic
SPBC16C6.05mitochondrial translation initiation factor (predicted) Negative Genetic
SPAC644.09alanine racemase (predicted) Positive Genetic
spc34DASH complex subunit Spc34 Negative Genetic
aut12autophagy associated protein Aut12 (predicted) Negative Genetic
SPAC1B3.02ctranscription elongation factor, Elf1 family (predicted) Negative Genetic
SPBC1861.07elongin C (predicted) Negative Genetic
SPBC15C4.06cubiquitin-protein ligase E3 (predicted) Negative Genetic
spf1Set1C PHD Finger protein Spf1 Negative Genetic
bdf1Swr1 complex bromodomain subunit Brf1 Negative Genetic
dad2DASH complex subunit Dad2 Negative Genetic
snf5SWI/SNF complex subunit Snf5 Negative Genetic
set11ribosomal protein lysine methyltransferase Set11 Negative Genetic
arp42SWI/SNF and RSC complex subunit Arp42 Negative Genetic
dad1DASH complex subunit Dad1 Negative Genetic
reb1RNA polymerase I transcription termination factor Reb1 Positive Genetic
SPCC18.10pyridoxine-pyridoxal-pyridoxamine kinase (predicted) Negative Genetic
swr1SNF2 family helicase Swr1 Negative Genetic
bdc1bromodomain containing protein 1, Bdc1 Negative Genetic
rcd1RNA-binding protein, CCR4-NOT complex subunit Rcd1 Positive Genetic
spn1septin Spn1 Negative Genetic
syj1inositol-polyphosphate 5-phosphatase (synaptojanin homolog 1) Negative Genetic
ers1RNA-silencing factor Ers1 Negative Genetic
chp1chromodomain protein Chp1 Negative Genetic
pmp1dual-specificity MAP kinase phosphatase Pmp1 Negative Genetic
SPBC36B7.08cnucleosome assembly protein (predicted) Negative Genetic
set3histone lysine methyltransferase Set3 Negative Genetic
rad26ATRIP, ATR checkpoint kinase regulatory subunit Rad26 Negative Genetic
par1protein phosphatase regulatory subunit Par1 Negative Genetic
pob3FACT complex component Pob3 Negative Genetic
mug81ATP-dependent RNA helicase Slh1 (predicted) Positive Genetic
mad2spindle checkpoint protein Mad2 Negative Genetic
swi2Swi5 complex subunit Swi2 Positive Genetic
SPAC3A11.13prefoldin subunit 6 (predicted) Positive Genetic
myp2myosin II heavy chain Myo3 Negative Genetic
SPAC12B10.01cubiquitin-protein ligase E3 (predicted) Negative Genetic
rhp57RecA family ATPase Rhp57 Negative Genetic
set5histone lysine methyltransferase Set5 (predicted) Negative Genetic
ubp3ubiquitin C-terminal hydrolase Ubp3 Negative Genetic
pms1MutL family mismatch-repair protein Pms1 Negative Genetic
ctf18RFC-like complex subunit Ctf18 Negative Genetic
spp27RNA polymerase I upstream activation factor complex subunit Spp27 Negative Genetic
SPBC13E7.08cRNA polymerase II associated Paf1 complex (predicted) Positive Genetic
rpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative Genetic
ies2Ino80 complex subunit Ies2 Negative Genetic
air1zinc knuckle TRAMP complex subunit Air1 Positive Genetic
epe1Jmjc domain chromatin associated protein Epe1 Negative Genetic
clr6histone deacetylase (class I) Clr6 Negative Genetic
swc5Swr1 complex subunit Swc5 Negative Genetic
nup60nucleoporin Nup60 Negative Genetic
hif2Set3 complex subunit Hif2 Negative Genetic
hrp3ATP-dependent DNA helicase Hrp3 Negative Genetic
ptn1phosphatidylinositol-3,4,5-trisphosphate3-phosphatasePtn1 Negative Genetic
pku80Ku domain protein Pku80 Negative Genetic
SPAC1952.02ribosome biogenesis protein (predicted) Positive Genetic
swc2Swr1 complex complex subunit Swc2 Negative Genetic
nup37WD repeat protein, nucleoporin Nup37 (predicted) Positive Genetic
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative Genetic
fft3fun thirty related protein Fft3 Negative Genetic
swd1Set1C complex subunit Swd1 Negative Genetic
xap5xap-5-like protein Negative Genetic
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative Genetic
nto1histone acetyltransferase complex subunit Nto1 (predicted) Negative Genetic
hrd1ubiquitin-protein ligase Hrd1, synviolin family Negative Genetic
cce1mitochondrial cruciform cutting endonuclease Cce1 Negative Genetic
iqw1WD repeat protein, Iqw1 Negative Genetic
ccr4CCR4-Not complex subunit Ccr4 (predicted) Positive Genetic
klp6kinesin-like protein Klp6 Negative Genetic
SPBC31F10.12RNA-binding protein Tma20 (predicted) Negative Genetic
SPBC16H5.13WD repeat protein, human WDR7 ortholog Negative Genetic
SPBC11C11.11cmitochondrial ATP-dependent DNA helicase Irc3 (predicted) Negative Genetic
nup61nucleoporin Nup61 Negative Genetic
hos2histone deacetylase (class I) Hos2 Negative Genetic
knd1TATA-binding protein (predicted) Positive Genetic
raf1Rik1-associated factor Raf1 Negative Genetic
rad32Rad32 nuclease Negative Genetic
snt2Lid2 complex subunit Snt2 Negative Genetic
SPBC4B4.04translation initiation factor eIF2A (predicted) Negative Genetic
hst2Sir2 family histone deacetylase Hst2 Negative Genetic
sgf29SAGA complex subunit Sgf29 Negative Genetic
SPBC11C11.10tRNA pseudouridine synthase (predicted) Negative Genetic
bub3mitotic spindle checkpoint protein Bub3 Negative Genetic
dsk1SR protein-specific kinase Dsk1 Negative Genetic
stp1dual specificity phosphatase Stp1 Positive Genetic
hhf1histone H4 h4.1 Negative Genetic
ufd2ubiquitin-protein ligase E4 (predicted) Negative Genetic
arp8actin-like protein Arp8 Negative Genetic
msc1multi-copy suppressor of Chk1 Negative Genetic
png2ING family homolog Png2 Negative Genetic
SPCC548.05cubiquitin-protein ligase E3 (predicted) Negative Genetic
dcr1dicer Negative Genetic
cyp3cyclophilin family peptidyl-prolyl cis- trans isomerase Cyp3 Negative Genetic
yaf9YEATS family histone acetyltransferase subunit Yaf9 Negative Genetic
SPAC1952.06cDUF1716 family protein Negative Genetic
ssu72phosphoric ester hydrolase Ssu72 (predicted) Negative Genetic
srb7mediator complex subunit Srb7 Negative Genetic
hip4histone promoter control protein Hip4 Negative Genetic
mal3EB1 family Mal3 Negative Genetic


External References

Database Identifier Description
NBRP SPBC2F12.12c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC2F12.12c Retrieval of eukaryotic orthologs
BioGrid SPBC2F12.12c BioGRID Interaction Datasets
Bähler Lab SPBC2F12.12c Cell Cycle Expression Profile
Bähler Lab SPBC2F12.12c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC2F12.12c Pheromone response/mating expression profiles
Bähler Lab SPBC2F12.12c Environmental stress expression profiles
Bähler Lab SPBC2F12.12c Bähler Lab Transcriptome Viewer
Cyclebase SPBC2F12.12c Cell Cycle Data
Entrez Gene SPBC2F12.12c Link to Entrez Gene
SPD / RIKEN36/36C12Orfeome Localization Data
UniProtKB/SwissProtO14342Uncharacterized protein C2F12.12c
ArrayExpressO14342Link to ArrayExpress
RefSeq PeptideNP_595704hypothetical protein SPBC2F12.12c
RefSeq mRNANM_001021601972h- hypothetical protein (SPBC2F12.12c), mRNA
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveCAB10159ENA Protein Mapping
UniParcUPI000013A210UniProt Archive

Literature for SPBC2F12.12c

Search: UK PMC or PubMed