SPBC2G5.01

Gene Standard NameUnassigned ChromosomeII
Systematic IDSPBC2G5.01 Gene Start2576500
Synonyms Gene End2577868
ProductER protein involved in ER-nucleus signaling (predicted) Gene Length1369
Feature Typeprotein coding CDS Start2576621
Name Description CDS End2577745
Characterisation Statusbiological_role_inferred CDS Length1125

Ensembl Gene Location
  1. rec8
  2. orc1
  3. SPNCRNA.1529
  4. SPBC29A10.17
  5. SPBC29A10.16c
  6. SPBTRNAPHE.03
  7. SPBC2G5.01
  8. ckb2
  9. SPNCRNA.1530
  10. SPNCRNA.401
  11. ctu1
  12. SPBC2G5.04c
  13. SPNCRNA.1531
  14. SPNCRNA.402
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001491viable vegetative cellMicroscopySPBC2G5.01delta (deletion)deletionPMID:20473289
GO Biological Process

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0006984ER-nucleus signaling pathwayISSMGI:1914413GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005783endoplasmic reticulumIDAPMID:16823372
ISOSGD:S000005304GO_REF:0000024
GO:0005789endoplasmic reticulum membraneIEASL-0097GO_REF:0000039
GO:0016021integral to membraneIEAUniProtKB:KW-0812GO_REF:0000037
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
125765002577868

References

Region Start End Reference
three_prime_UTR25777462577868PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF07946 IPR012879 Pfam Protein of unknown function DUF1682 46 369 1
TMhelix TMHMM 49 68 955
PTHR12883 IPR012879 hmmpanther Protein of unknown function DUF1682 34 374 1
SignalP-TM signalp 1 19 16

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.23 Da
Charge 11.00
Isoelectric point 9.44
Molecular weight 43.10 kDa
Number of residues 374
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide4213.63PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide8939.21PMID:23101633
RNA levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide9PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:22681890
ppk16serine/threonine protein kinase Ppk16 (predicted) Positive GeneticPMID:22681890
ngg1SAGA complex subunit Ngg1 Negative GeneticPMID:22681890
rem1meiosis-specific cyclin Rem1 Negative GeneticPMID:22681890
ypa2protein phosphatase type 2A regulator, PTPA family Ypa2 Negative GeneticPMID:22681890
sdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Positive GeneticPMID:22681890
sfp1transcription factor Sfp1 (predicted) Negative GeneticPMID:22681890
ers1RNA-silencing factor Ers1 Positive GeneticPMID:22681890
tma23ribosome biogenesis protein Tma23 (predicted) Negative GeneticPMID:22681890
ufd2ubiquitin-protein ligase E4 (predicted) Positive GeneticPMID:22681890
rad51RecA family recombinase Rad51/Rhp51 Negative GeneticPMID:22681890
SPAC17A5.09cprotein phosphatase regulatory subunit Glc9 (predicted) Positive GeneticPMID:22681890
SPAC821.05translation initiation factor eIF3h (p40) Negative GeneticPMID:22681890
SPAC17H9.13cglutamate 5-kinase (predicted) Negative GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:22681890
SPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:22681890
rad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:22681890
SPCC1450.09cphospholipase (predicted) Positive GeneticPMID:22681890
SPBC1861.07elongin C (predicted) Positive GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:22681890
SPCC1322.02sequence orphan Negative GeneticPMID:22681890
SPAC1A6.03cphospholipase (predicted) Positive GeneticPMID:22681890
rad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPBC2G5.01 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC2G5.01 Retrieval of eukaryotic orthologs
BioGrid SPBC2G5.01 BioGRID Interaction Datasets
Bähler Lab SPBC2G5.01 Cell Cycle Expression Profile
Bähler Lab SPBC2G5.01 Meiosis/Sporulation Expression Profies
Bähler Lab SPBC2G5.01 Pheromone response/mating expression profiles
Bähler Lab SPBC2G5.01 Environmental stress expression profiles
Bähler Lab SPBC2G5.01 Bähler Lab Transcriptome Viewer
Cyclebase SPBC2G5.01 Cell Cycle Data
PInt SPBC2G5.01 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC2G5.01 Entrez Gene
SPD / RIKEN17/17F11Orfeome Localization Data
WikiGene2540360DUF1682 family protein
EntrezGene2540360DUF1682 family protein
UniProtKB/SwissProtO94280UPF0674 endoplasmic reticulum membrane protein C2G5.01
ModBaseO94280Database of comparative protein structure models
Pfam Protein DomainsO94280Pfam Domain Arrangement
RefSeq PeptideNP_596062DUF1682 family protein
RefSeq mRNANM_001021973972h- DUF1682 family protein (SPBC2G5.01), mRNA
European Nucleotide ArchiveCAA21877ENA Protein Mapping
SPD / RIKEN17/17F11Orfeome Localization Data

Literature for SPBC2G5.01
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013