rpl102 (SPBC30D10.18c)


Gene Standard Namerpl102 Characterisation Statuspublished
Systematic IDSPBC30D10.18c Feature Typeprotein coding
Synonymsrpl1-2, rpl10a-2 Name Description
Product60S ribosomal protein L10a Product Size216aa, 23.88 kDa
Genomic Location Chromosome II, 3060505-3061591 (1087nt); CDS:3060570-3061481 (912nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003735structural constituent of ribosomeISOSGD:S000003103GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002181cytoplasmic translationNASGO_REF:0000051445
GO:0006412translationISOSGD:S000003103GO_REF:0000024597
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722316
GO:0022625cytosolic large ribosomal subunitISOSGD:S000003103GO_REF:000002482
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyrpl102ΔNullPECO:0000005, PECO:0000137PMID:236978063730
Microscopyrpl102ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyrpl102ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
130605053060957
230612193061591

UTRs

Region Coordinates Reference
five_prime_UTR3060505..3060569PMID:21511999
three_prime_UTR3061482..3061591PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00687 Pfam IPR028364 Ribosomal protein L1/ribosomal biogenesis protein 17 211 5
PS01199 Prosite Patterns IPR023673 Ribosomal protein L1, conserved site 116 135 2
PTHR23105:SF31 HMMPANTHER 1 216 2
PTHR23105 HMMPANTHER 1 216 8
3.30.190.20 Gene3D IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich 152 216 5
3.30.190.20 Gene3D IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich 12 60 5
3.40.50.790 Gene3D IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich 62 151 4
SSF56808 SuperFamily IPR023674 Ribosomal protein L1-like 3 216 5
PIRSF002155 PIRSF IPR002143 Ribosomal protein L1 1 216 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.58 Da
Charge 18.00
Isoelectric point 10.48
Molecular weight 23.88 kDa
Number of residues 216
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
66360during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
66464during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
66656during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
69779during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
22642.58during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
70693during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
4385.59during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
11during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
3.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4569
conserved in eukaryotes4482
conserved in bacteria1001
conserved in metazoa3419
conserved in vertebrates3393
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
SPCC162.11curidine kinase/uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:22681890
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Positive GeneticPMID:22681890
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:22681890
clr4histone H3 lysine methyltransferase Clr4 Positive GeneticPMID:22681890
rad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
atg6beclin family protein, involved in autophagy Positive GeneticPMID:22681890
epe1Jmjc domain chromatin associated protein Epe1 Positive GeneticPMID:22681890
rpb7DNA-directed RNA polymerase complex II subunit Rpb7 Positive GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
External References
Database Identifier Description
NBRP SPBC30D10.18c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC30D10.18c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC30D10.18c BioGRID Interaction Datasets
Expression Viewer SPBC30D10.18c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC30D10.18c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC30D10.18c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC30D10.18c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC30D10.18c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC30D10.18c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC30D10.18c Cell Cycle Data
GEO SPBC30D10.18c GEO profiles
PInt SPBC30D10.18c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC30D10.18c Peptides identified in tandem mass spectrometry proteomics experiments
EntrezGene254037860S ribosomal protein L10a
WikiGene254037860S ribosomal protein L10a
SPD / RIKEN32/32A12Orfeome Localization Data
UniProtKB/SwissProtO1436360S ribosomal protein L1-A
ModBaseO14363Database of comparative protein structure models
STRINGO14363Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59626760S ribosomal protein L10a
RefSeq mRNANM_001022188972h- 60S ribosomal protein L10a (rpl102), mRNA
European Nucleotide ArchiveCAB10813ENA Protein Mapping
European Nucleotide ArchiveCAB10813.1ENA Protein Mapping
ReactomeREACT_188294
ReactomeREACT_188542
ReactomeREACT_188560
ReactomeREACT_206850
ReactomeREACT_215930
UniParcUPI0000132EB3UniProt Archive

Literature for rpl102

Search: Europe PMC or PubMed

Release Version: PomBase:22_45 - 08 Aug 2014