rpl102 (SPBC30D10.18c)


Gene Standard Namerpl102 Characterisation Statuspublished
Systematic IDSPBC30D10.18c Feature Typeprotein coding
Synonymsrpl1-2, rpl10a-2 Name Description
Product60S ribosomal protein L10a Product Size216aa, 23.88 kDa
Genomic Location Chromosome II, 3060505-3061591 (1087nt); CDS:3060570-3061481 (912nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome257
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation469
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2302
Annotation ExtensionEvidenceWith/FromReference
cytosolic large ribosomal subunit83
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
viable vegetative cell populationrpl102Δ3840

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologyrpl102Δ3100
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3060505..3060957, 3061219..3061591
Intron3060958..3061218
mRNA3060505..3061591
5' UTR3060505..3060569PMID:21511999
CDS3060570..3060957, 3061219..3061481
3' UTR3061482..3061591PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00687 Pfam IPR028364 Ribosomal protein L1/ribosomal biogenesis protein 18 211 5
PS01199 Prosite Patterns IPR023673 Ribosomal protein L1, conserved site 116 135 2
PTHR23105 HMMPANTHER 1 216 8
PTHR23105:SF54 HMMPANTHER 1 216 2
3.40.50.790 Gene3D IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich 62 151 4
3.30.190.20 Gene3D IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich 152 216 5
3.30.190.20 Gene3D IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich 12 60 5
SSF56808 SuperFamily IPR023674 Ribosomal protein L1-like 3 216 5
PIRSF002155 PIRSF IPR002143 Ribosomal protein L1 1 216 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.58 Da
Charge 18.00
Codon Adaptation Index 0.61
Isoelectric point 10.48
Molecular weight 23.88 kDa
Number of residues 216
Modifications

Protein Modifications

Term NameResidueCount
ubiquitinylated lysineK77 512
Annotation ExtensionEvidenceResidueReference
mass spectrometry evidence K77 PMID:26412298
IDA PMID:26412298
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for rpl102 (SPBC30D10.18c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
66360during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
66464during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
66656during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
69779during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
70693during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
22642.58during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
4385.59during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
11during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
3.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4606
conserved in eukaryotes4516
conserved in bacteria1001
conserved in metazoa3424
conserved in vertebrates3399
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPBC30D10.18c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withclr4histone H3 lysine methyltransferase Clr4 Positive GeneticPMID:22681890
positive genetic interaction withrpb7DNA-directed RNA polymerase complex II subunit Rpb7 Positive GeneticPMID:22681890
positive genetic interaction withepe1Jmjc domain chromatin associated protein Epe1 Positive GeneticPMID:22681890
positive genetic interaction withatg6autophagy associated beclin family protein Atg6 Positive GeneticPMID:22681890
positive genetic interaction withypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Positive GeneticPMID:22681890
positive genetic interaction withurk1uridine kinase/uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withrad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
negative genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withhrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPBC30D10.18c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC30D10.18c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC30D10.18c BioGRID Interaction Datasets
Expression Viewer SPBC30D10.18c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC30D10.18c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC30D10.18c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC30D10.18c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC30D10.18c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC30D10.18c Transcriptome Viewer (Bähler Lab)
GEO SPBC30D10.18c GEO profiles
PInt SPBC30D10.18c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC30D10.18c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC30D10.18c Fission yeast phenotypic data & analysis
Cyclebase SPBC30D10.18c.1 Cell Cycle Data
SPD / RIKEN32/32A12Orfeome Localization Data
UniProtKB/SwissProtO1436360S ribosomal protein L1-A
ModBaseO14363Database of comparative protein structure models
STRINGO14363Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59626760S ribosomal protein L1
RefSeq mRNANM_001022188972h- 60S ribosomal protein L1 (rpl102), mRNA

Literature for rpl102

Search: Europe PMC or PubMed

Release Version: PomBase:30_59 - 12 Apr 2016