gle1 (SPBC31E1.05)

Gene Standard Namegle1 ChromosomeII
Systematic IDSPBC31E1.05 Gene Start247207
Synonyms Gene End248977
ProductRNA export factor, cytoplasmic nucleoporin Gle1 Gene Length1771
Feature Typeprotein coding CDS Start247261
Name Description CDS End248753
Characterisation Statuspublished CDS Length1493

Ensembl Gene Location
  1. pmr1
  2. hub1
  3. pep12
  4. gle1
  5. bms1
  6. whi5
  7. SPNCRNA.1331
  8. clr3
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001489inviable vegetative cellMicroscopygle1delta (deletion)deletionPMID:20473289
no_name (unrecorded)unrecordedPMID:18758733
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0031369translation initiation factor bindingISOSGD:S000002366GO_REF:0000024
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0015031protein transportIEAUniProtKB:KW-0653GO_REF:0000037
GO:0016973poly(A)+ mRNA export from nucleusIMPPMID:18758733
IGIrae1PMID:18758733
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005635nuclear envelopeIDAPMID:16823372
GO:0005643nuclear poreISOSGD:S000002366GO_REF:0000024
IDAGO_REF:0000001
exists_during mitotic cell cycleIDAPMID:20970342
exists_during meiotic cell cycleIDAPMID:20970342
GO:0005829cytosolIDAPMID:16823372
GO:0031965nuclear membraneIEASL-0182GO_REF:0000039
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1247207247398
2247449248977

References

Region Start End Reference
three_prime_UTR248754248977PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF07817 IPR012476 Pfam GLE1-like 203 443 1
Coil ncoils Rabaptin coiled-coil domain 91 189 974
PTHR12960 IPR012476 hmmpanther GLE1-like 14 471 1
PTHR12960:SF0 hmmpanther 14 471 1

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReference
SO:0001531nuclear_export_signal

Protein Properties

Ave. residue weight 117.28 Da
Charge 16.50
Isoelectric point 9.55
Molecular weight 56.29 kDa
Number of residues 480
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide1174.5PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.52PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide2.5PMID:23101633
Disease Association
DescriptionQualifierReference
neurological disorders
motor neurone disease
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
alp14TOG ortholog Alp14 Dosage RescuePMID:15507118
sui1translation initiation factor eIF1 Dosage RescuePMID:15507118
SPBC12C2.06cytoplasmic ATP-dependent RNA helicase Dbp5 (predicted) Dosage RescuePMID:15507118
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External References
Database Identifier Description
NBRP SPBC31E1.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC31E1.05 Retrieval of eukaryotic orthologs
BioGrid SPBC31E1.05 BioGRID Interaction Datasets
Bähler Lab SPBC31E1.05 Cell Cycle Expression Profile
Bähler Lab SPBC31E1.05 Meiosis/Sporulation Expression Profies
Bähler Lab SPBC31E1.05 Pheromone response/mating expression profiles
Bähler Lab SPBC31E1.05 Environmental stress expression profiles
Bähler Lab SPBC31E1.05 Bähler Lab Transcriptome Viewer
Cyclebase SPBC31E1.05 Cell Cycle Data
PInt SPBC31E1.05 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC31E1.05 Entrez Gene
SPD / RIKEN24/24B02Orfeome Localization Data
EntrezGene2540395RNA export factor Gle1
Uniprot_genenameGLE1
WikiGene2540395RNA export factor Gle1
UniProtKB/SwissProtO94652Nucleoporin gle1
ModBaseO94652Database of comparative protein structure models
Pfam Protein DomainsO94652Pfam Domain Arrangement
RefSeq PeptideNP_595101RNA export factor Gle1
RefSeq mRNANM_001021008972h- RNA export factor Gle1 (gle1), mRNA
European Nucleotide ArchiveCAB39139ENA Protein Mapping
SPD / RIKEN24/24B02Orfeome Localization Data

Literature for gle1
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013