hip1 (SPBC31F10.13c)

Gene Standard Namehip1 ChromosomeII
Systematic IDSPBC31F10.13c Gene Start3777499
Synonymshir1 Gene End3774138
Producthira protein, histone chaperone Hip1 Gene Length3362
Feature Typeprotein coding CDS Start3777350
Name DescriptionHIRA Interacting Protein CDS End3774357
Characterisation Statuspublished CDS Length2994

Ensembl Gene Location
  1. SPBC31F10.10c
  2. SPNCRNA.1637
  3. cwf4
  4. tma20
  5. hip1
  6. SPNCRNA.1638
  7. SPNCRNA.1639
  8. hip3
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000088sensitive to hydroxyureacompetitive growth assay evidencehip1delta (deletion)deletionPMID:20537132
FYPO:0000266sensitive to DNA damaging agentscompetitive growth assay evidencehip1delta (deletion)deletionPMID:20537132
FYPO:0000623abnormal positive regulation of transcriptionQuantitative PCRhip1delta (deletion)deletionPMID:17452352
has_regulation_target hhf2
has_regulation_target hht2Quantitative PCRhip1delta (deletion)deletionPMID:17452352
has_regulation_target hht1Quantitative PCRhip1delta (deletion)deletionPMID:17452352
has_regulation_target hta1Quantitative PCRhip1delta (deletion)deletionPMID:17452352
has_regulation_target hhf3Quantitative PCRhip1delta (deletion)deletionPMID:17452352
has_regulation_target hht3Quantitative PCRhip1delta (deletion)deletionPMID:17452352
has_regulation_target hta2Quantitative PCRhip1delta (deletion)deletionPMID:17452352
has_regulation_target hhf1Quantitative PCRhip1delta (deletion)deletionPMID:17452352
FYPO:0002060viable vegetative cell populationMicroscopyhip1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0003682chromatin bindingIEAIPR019015GO_REF:0000002
GO:0003714transcription corepressor activityTASPMID:15121850
GO:0005515protein bindingIPIslm9PMID:15121850
IPImst1PMID:18505873
IPIcia1PMID:18334479
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0000070mitotic sister chromatid segregationIMPPMID:15121850
GO:0006336DNA replication-independent nucleosome assemblyTASPMID:16428807
GO:0006995cellular response to nitrogen starvationIMPPMID:15121850
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosisIMPPMID:16428807
GO:0007346regulation of mitotic cell cycleIMPPMID:15121850
GO:0016568chromatin modificationIEAUniProtKB:KW-0156GO_REF:0000037
GO:0030466chromatin silencing at silent mating-type cassetteIMPPMID:15121850
GO:0030702chromatin silencing at centromere
occurs_at regional_centromere_outer_repeat_regionIMPPMID:15121850
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0000417HIR complexIDAPMID:20976105
GO:0000790nuclear chromatinICGO:0003714PMID:15121850
GO:0005634nucleusIDAPMID:15121850
IDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
137774993777314
237772553777178
337771213776923
437768813776790
537767493774138

References

Region Start End Reference
three_prime_UTR37743563774138PMID:21511999
three_prime_UTR37743563774138PMID:21511999
five_prime_UTR37774993777351PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00400 IPR001680 Pfam WD40 repeat 15 46 104
PF00400 IPR001680 Pfam WD40 repeat 128 162 104
PF00400 IPR001680 Pfam WD40 repeat 69 102 104
PF00400 IPR001680 Pfam WD40 repeat 264 307 104
PF00400 IPR001680 Pfam WD40 repeat 169 203 104
PF07569 IPR011494 Pfam TUP1-like enhancer of split 663 886 2
PF09453 IPR019015 Pfam HIRA B motif 475 497 1
SM00320 IPR001680 SMART WD40 repeat 259 307 120
SM00320 IPR001680 SMART WD40 repeat 5 46 120
SM00320 IPR001680 SMART WD40 repeat 63 102 120
SM00320 IPR001680 SMART WD40 repeat 165 204 120
SM00320 IPR001680 SMART WD40 repeat 123 162 120
SM00320 IPR001680 SMART WD40 repeat 311 350 120
PS50294 IPR017986 Prosite Profiles WD40-repeat-containing domain 14 213 104
PS50082 IPR001680 Prosite Profiles WD40 repeat 172 213 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 130 171 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 70 101 100
PS50082 IPR001680 Prosite Profiles WD40 repeat 14 55 100
PS00678 IPR019775 Prosite Patterns WD40 repeat, conserved site 149 163 65
G3DSA:2.130.10.10 IPR015943 Gene3D 15 243 144
G3DSA:2.130.10.10 IPR015943 Gene3D 255 356 144
G3DSA:2.130.10.10 IPR015943 Gene3D 599 708 144
SSF50978 IPR017986 SuperFamily 16 349 135
PTHR13831 hmmpanther 1 887 2
PTHR13831:SF0 hmmpanther 1 887 2

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000190WD repeat proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000190

Protein Properties

Ave. residue weight 111.25 Da
Charge 3.50
Isoelectric point 6.74
Molecular weight 103.69 kDa
Number of residues 932
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
deletion mutant expression profiling PMID:19620282
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1386.26PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide1718.39PMID:23101633
RNA levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide2.2PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.89PMID:23101633
Miscellaneous Functional Group
DescriptionQualifierReference
histone chaperone
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
rhn1RNA polymerase II transcription termination factor homolog Positive GeneticPMID:18818364
clr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
pli1SUMO E3 ligase Pli1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
fsv1SNARE Fsv1 Positive GeneticPMID:22681890
SPAC3H8.04chromosome segregation protein (predicted) Positive GeneticPMID:22681890
nup40nucleoporin Nup40 Negative GeneticPMID:18818364
sif3Sad1 interacting factor 3 (predicted) Negative GeneticPMID:22681890
exg3glucan 1,3-beta-glucosidase Exg3 Positive GeneticPMID:22681890
psh3ER chaperone SHR3 homologue Psh3 Negative GeneticPMID:22681890
atp11F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
mcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:22681890
hta1histone H2A alpha Negative GeneticPMID:22681890
nap1nucleosome assembly protein Nap1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ppk29Ark1/Prk1 family protein kinase Ppk29 Positive GeneticPMID:22681890
snr13-hydroxyisobutyryl-CoA hydrolase snr1 Positive GeneticPMID:22681890
bdf1Swr1 complex bromodomain subunit Brf1 Negative GeneticPMID:18818364
mgr2mitochondrial membrane protein Mgr2 (predicted) Negative GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Positive GeneticPMID:22681890
dnm1dynamin Dnm1 Positive GeneticPMID:18818364
SPAC8E11.01cbeta-fructofuranosidase (predicted) Positive GeneticPMID:22681890
SPBC30B4.06cmitochondrial GIDA family tRNA uridine 5-carboxymethylaminomethyl modification enzyme (predicted) Positive GeneticPMID:22681890
mrc1mediator of replication checkpoint 1 Negative GeneticPMID:18818364
SPBC1198.01glutathione-dependent formaldehyde dehydrogenase (predicted) Positive GeneticPMID:22681890
SPBC19F8.02nuclear distribution protein NUDC homolog Negative GeneticPMID:22681890
SPCC18B5.10cTREX complex subunit Tex1 (predicted) Positive GeneticPMID:18818364
spo6Spo4-Spo6 kinase complex regulatory subunit Spo6 Negative GeneticPMID:18818364
SPBC2D10.04arrestin Aly1 related, implicated in endocytosis Positive GeneticPMID:22681890
pob3FACT complex subunit Pob3 Negative GeneticPMID:18818364
alp31tubulin specific chaperone cofactor A, Alp31 Negative GeneticPMID:18818364
gld1mitochondrial glycerol dehydrogenase Gld1 Positive GeneticPMID:22681890
SPAC977.17MIP water channel (predicted) Negative GeneticPMID:22681890
SPCC663.10tRNA (uracil) methyltransferase (predicted) Positive GeneticPMID:22681890
spo20sec14 cytosolic factor family Sec14 Negative GeneticPMID:22681890
cch1calcium channel Cch1 Positive GeneticPMID:22681890
SPBC30D10.14dienelactone hydrolase family (predicted) Negative GeneticPMID:22681890
raf2Rik1-associated factor Raf2 Negative GeneticPMID:18818364
SPCC70.06nuclear export factor (predicted) Phenotypic SuppressionPMID:19547744
pho24-nitrophenylphosphatase Negative GeneticPMID:22681890
atp12F1-ATPase chaperone Atp12 (predicted) Positive GeneticPMID:22681890
ies4Ino80 complex subunit Ies4 Negative GeneticPMID:22681890
nup60nucleoporin Nup60 Negative GeneticPMID:18818364
mlo2ubiquitin protein ligase E3 component human N-recognin 7 homolog Mlo2 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
ptn1phosphatidylinositol-3,4,5-trisphosphate3-phosphatase Ptn1 Negative GeneticPMID:18818364
ypa2protein phosphatase type 2A regulator, PTPA family Ypa2 Negative GeneticPMID:18818364
SPAC5D6.04auxin family transmembrane transporter (predicted) Positive GeneticPMID:22681890
SPBC14C8.11csequence orphan Positive GeneticPMID:22681890
lag1sphingosine N-acyltransferase Lag1 Positive GeneticPMID:22681890
SPBPB10D8.04cmembrane transporter (predicted) Negative GeneticPMID:22681890
rdp1RNA-directed RNA polymerase Rdp1 Negative GeneticPMID:18818364
dbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:18818364
pmt1tRNA methyltransferase Positive GeneticPMID:22681890
SPAPB8E5.04cNiemann-Pick disease type C2 protein hE1 homolog (predicted) Positive GeneticPMID:22681890
SPBC9B6.03zf-FYVE type zinc finger protein Positive GeneticPMID:22681890
SPCC364.04cCASP family protein involved in Golgi vesicle transport (predicted) Positive GeneticPMID:22681890
SPAC1805.14sequence orphan Negative GeneticPMID:22681890
SPAC3F10.06cinitiator methionine tRNA 2'-O-ribosyl phosphate transferase (predicted) Negative GeneticPMID:22681890
bub3mitotic spindle checkpoint protein Bub3 Negative GeneticPMID:22681890
pyp1tyrosine phosphatase Pyp1 Negative GeneticPMID:22681890
moe1translation initiation factor eIF3d Moe1 Negative GeneticPMID:22681890
not3CCR4-Not complex subunit Not3/5 (predicted) Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
cdk11serine/threonine protein kinase cdk11 Negative GeneticPMID:18818364
sdh3succinate dehydrogenase (ubiquinone) cytochrome b subunit (predicted) Positive GeneticPMID:22681890
pub1HECT-type ubiquitin-protein ligase E3 Pub1 Negative GeneticPMID:22681890
SPBC660.17csequence orphan Positive GeneticPMID:22681890
pcf2CAF assembly factor (CAF-1) complex subunit B, Pcf2 Negative GeneticPMID:18818364
dsc4Golgi Dsc E3 ligase complex subunit Dsc3 Positive GeneticPMID:22681890
SPBC1773.06calcohol dehydrogenase (predicted) Positive GeneticPMID:22681890
pds5cohesin-associated protein Pds5 Negative GeneticPMID:18818364
sif2Sad1 interacting factor 2 (predicted) Negative GeneticPMID:22681890
SPCC1442.11csequence orphan Positive GeneticPMID:22681890
iwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:18818364
SPBC21B10.07glycosyl hydrolase family 16 (predicted) Positive GeneticPMID:22681890
mto1MT organizer Mto1 Negative GeneticPMID:22681890
hmt1ATP-binding cassette-type vacuolar membrane transporter Hmt1 Negative GeneticPMID:22681890
mug113T5orf172 family protein Positive GeneticPMID:22681890
fis1mitochondrial fission protein Fis1 (predicted) Positive GeneticPMID:22681890
SPAC589.03csequence orphan Positive GeneticPMID:22681890
omh6alpha-1,2-mannosyltransferase Omh6 (predicted) Negative GeneticPMID:22681890
apq12nuclear membrane organization protein Apq12 (predicted) Negative GeneticPMID:22681890
SPAC17H9.13cglutamate 5-kinase (predicted) Negative GeneticPMID:22681890
dad1DASH complex subunit Dad1 Positive GeneticPMID:22681890
SPBC24C6.04delta-1-pyrroline-5-carboxylate dehydrogenase (predicted) Negative GeneticPMID:22681890
moc3transcription factor Moc3 Positive GeneticPMID:22681890
rpl230160S ribosomal protein L23 Negative GeneticPMID:22681890
SPCC18.10pyridoxine-pyridoxal-pyridoxamine kinase (predicted) Positive GeneticPMID:22681890
SPAC25B8.05tRNA-pseudouridine synthase (predicted) Positive GeneticPMID:18818364
bdc1bromodomain containing protein 1, Bdc1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
spt2non-specific DNA binding protein Spt2 (predicted) Negative GeneticPMID:18818364
sdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Positive GeneticPMID:18818364
csk1cyclin-dependent kinase activating kinase Csk1 Negative GeneticPMID:22681890
ers1RNA-silencing factor Ers1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
chp1chromodomain protein Chp1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
hat1histone acetyltransferase Hat1 Negative GeneticPMID:22681890
ucp6UBA domain protein Ucp6 Positive GeneticPMID:22681890
SPCC16C4.06ctRNA pseudouridine synthase (predicted) Negative GeneticPMID:22681890
SPAC30D11.14cRNA-binding protein (predicted) Negative GeneticPMID:22681890
res2MBF transcription factor complex subunit Res2 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
taf1Taz1 interacting factor 1, autophagy protein Positive GeneticPMID:22681890
SPAC3H8.08ctranscription factor (predicted) Positive GeneticPMID:22681890
wis2cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Negative GeneticPMID:18818364
vht1vitamin H transporter Vth1 Negative GeneticPMID:22681890
for3formin For3 Synthetic Growth DefectPMID:18931302
byr3zinc finger protein Byr3 Negative GeneticPMID:22681890
rud3Golgi matrix protein Rud3 (predicted) Synthetic Growth DefectPMID:18931302
spf31DNAJ protein Spf31 (predicted) Positive GeneticPMID:22681890
trk1potassium ion transporter Trk1 Positive GeneticPMID:22681890
bst1GPI inositol deacylase Bst1 (predicted) Negative GeneticPMID:22681890
mtg1mitochondrial GTPase involved in translation Mtg1 (predicted) Positive GeneticPMID:22681890
apm4AP-2 adaptor complex subunit Apm4 (predicted) Negative GeneticPMID:22681890
SPAC977.13chydrolase, pseudogene Positive GeneticPMID:22681890
fft3fun thirty related protein Fft3 Negative GeneticPMID:18818364
SPAC22H12.05cfasciclin domain protein Positive GeneticPMID:22681890
pac2cAMP-independent regulatory protein Pac2 Negative GeneticPMID:22681890
swd1Set1C complex subunit Swd1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
hos2histone deacetylase (class I) Hos2 Negative GeneticPMID:18818364
mpc1mitochondrial pyruvate transmembrane transporter subunit Mpc1 Negative GeneticPMID:22681890
fcf2rRNA processing protein Fcf2 (predicted) Negative GeneticPMID:22681890
sec28coatomer epsilon subunit (predicted) Negative GeneticPMID:18818364
mms19Dos2 silencing complex subunit Mms19 Negative GeneticPMID:18818364
SPCC550.03cSki complex RNA helicase Ski2 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
sgf73SAGA complex subunit Sgf73 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
otu2ubiquitin specific cysteine protease, OTU family, Otu2 Positive GeneticPMID:22681890
SPAC26H5.02cDNA replication ATPase (predicted) Positive GeneticPMID:18818364
SPCC18.17c26S proteasome non-ATPase regulatory subunit (predicted) Negative GeneticPMID:22681890
pmr1P-type ATPase, calcium transporting Pmr1 Negative GeneticPMID:22681890
mni1Mago Nashi interacting protein (predicted) Negative GeneticPMID:22681890
dcr1dicer Negative GeneticPMID:18818364
elp5elongator complex subunit Elp5 (predicted) Negative GeneticPMID:18818364
SPBC1734.07cTRAPP complex subunit Trs85 (predicted) Positive GeneticPMID:18818364
snz1pyridoxine biosynthesis protein Negative GeneticPMID:22681890
SPCC306.11sequence orphan Positive GeneticPMID:22681890
SPBC354.04sequence orphan Positive GeneticPMID:22681890
SPAC1952.09cacetyl-CoA hydrolase (predicted) Positive GeneticPMID:22681890
pmc5mediator complex subunit Pmc5 Negative GeneticPMID:18818364
shy1SURF-family protein Shy1 (predicted) Positive GeneticPMID:22681890
tip1CLIP170 family protein Tip1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
mug28RNA-binding protein Mug28 Positive GeneticPMID:18818364
rap1telomere binding protein Rap1 Negative GeneticPMID:18818364
pfa3palmitoyltransferase Pfa3 (predicted) Positive GeneticPMID:22681890
SPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:18818364
clr3histone deacetylase (class II) Clr3 Phenotypic EnhancementPMID:21211723
Negative GeneticPMID:18818364
mug154conserved fungal protein Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ago1argonaute Negative GeneticPMID:18818364
rpl190260S ribosomal protein L19 Negative GeneticPMID:22681890
rrf1mitochondrial translation termination factor Rrf1 Positive GeneticPMID:22681890
mug176BRCT domain protein Negative GeneticPMID:22681890
ask1DASH complex subunit Ask1 Negative GeneticPMID:18818364
SPCC1919.05Ski complex TPR repeat subunit Ski3 (predicted) Negative GeneticPMID:22681890
pof3F-box protein Pof3 Synthetic Growth DefectPMID:18931302
SPCC757.04transcription factor (predicted) Positive GeneticPMID:22681890
spf1Set1C PHD Finger protein Spf1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
snf30SWI/SNF complex subunit Snf30 Positive GeneticPMID:18818364
dad2DASH complex subunit Dad2 Negative GeneticPMID:18818364
dis2serine/threonine protein phosphatase PP1 Synthetic Growth DefectPMID:21965289
SPAC6C3.08proteasome regulatory particle, gankyrin (predicted) Negative GeneticPMID:22681890
atg14autophagy specific phophatidylinositol 3-kinase complex subunit Atg14 (predicted) Positive GeneticPMID:22681890
SPCC1442.05cmitochondrial protein Positive GeneticPMID:22681890
reb1RNA polymerase I transcription termination factor Reb1 Negative GeneticPMID:18818364
mmd1deoxyhypusine hydroxylase (predicted) Synthetic Growth DefectPMID:18931302
pex11peroxisomal biogenesis factor 11 (predicted) Positive GeneticPMID:22681890
ngg1SAGA complex subunit Ngg1 Positive GeneticPMID:18818364
rad2514-3-3 protein Rad25 Positive GeneticPMID:18818364
SPAPJ691.03mitochondrial inner membrane organizing system protein (predicted) Positive GeneticPMID:22681890
cbs2protein kinase activator (predicted) Positive GeneticPMID:18818364
swd2Set1C complex subunit Swd2.1 Negative GeneticPMID:18818364
SPAC227.03cmitochondrial NAD transmembrane transporter (predicted) Positive GeneticPMID:22681890
SPBC36B7.08cnucleosome assembly protein (predicted) Positive GeneticPMID:22681890
srb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Negative GeneticPMID:22681890
SPCC1259.08conserved fungal protein, DUF2457 family Negative GeneticPMID:22681890
SPCC1494.08cconserved fungal protein Positive GeneticPMID:22681890
SPAC3A11.13prefoldin subunit 6 (predicted) Positive GeneticPMID:22681890
SPAC12B10.01cubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:18818364
sub1transcription coactivator PC4 Positive GeneticPMID:22681890
swd3WD repeat protein Swd3 Negative GeneticPMID:18818364
ctf18RFC-like complex subunit Ctf18 Negative GeneticPMID:18818364
spp27RNA polymerase I upstream activation factor complex subunit Spp27 Positive GeneticPMID:22681890
asp1inositol hexakisphosphate kinase/inositol pyrophosphate synthase (predicted) Negative GeneticPMID:22681890
rpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:18818364
SPBC365.07cTATA element modulatory factor homolog (predicted) Negative GeneticPMID:22681890
cul3cullin 3 Synthetic Growth DefectPMID:18931302
SPAC17H9.08mitochondrial coenzyme A transporter (predicted) Positive GeneticPMID:22681890
erf4palmitoyltransferase complex subunit Erf4 (predicted) Negative GeneticPMID:22681890
tas3RITS complex subunit 3 Phenotypic EnhancementPMID:21211723
elp3elongator complex, histone acetyltransferase subunit Elp3 (predicted) Negative GeneticPMID:18818364
arf6ADP-ribosylation factor, Arf family Arf6 Negative GeneticPMID:22681890
nup131nucleoporin Nup131 Positive GeneticPMID:18818364
hrp3ATP-dependent DNA helicase Hrp3 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
tea3cell end marker Tea3 Negative GeneticPMID:22681890
rpl90160S ribosomal protein L9 Negative GeneticPMID:22681890
SPBC21B10.08csequence orphan Negative GeneticPMID:22681890
mug14adducin Negative GeneticPMID:22681890
ser2phosphoserine phosphatase Ser2 (predicted) Negative GeneticPMID:18818364
SPBPB2B2.19cS. pombe specific 5Tm protein family Negative GeneticPMID:22681890
mug16UNC-50 family protein Negative GeneticPMID:22681890
not2CCR4-Not complex subunit Not2 (predicted) Positive GeneticPMID:18818364
SPAC10F6.13caspartate aminotransferase (predicted) Negative GeneticPMID:22681890
nse6Smc5-6 complex non-SMC subunit Nse6 Positive GeneticPMID:22681890
raf1Rik1-associated factor Raf1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC4A8.02cconserved protein, UPF0047 family Positive GeneticPMID:22681890
cgs2cAMP-specific phosphodiesterase Cgs2 Positive GeneticPMID:22681890
mug80cyclin Clg1 (predicted) Negative GeneticPMID:22681890
SPAC222.08cglutamine aminotransferase subunit (predicted) Negative GeneticPMID:22681890
rox3mediator complex subunit Med19/Rox3 Positive GeneticPMID:18818364
pdr1ABC transporter Pdr1 Negative GeneticPMID:22681890
hht2histone H3 h3.2 Negative GeneticPMID:18818364
pht1histone H2A variant H2A.Z, Pht1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
hhf1histone H4 h4.1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ddb1damaged DNA binding protein Ddb1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
cbp1CENP-B homolog Phenotypic EnhancementPMID:18094683
pmt3SUMO Negative GeneticPMID:22681890
pof9F-box protein Pof9 Positive GeneticPMID:22681890
exo1exonuclease I Exo1 Negative GeneticPMID:22681890
mal3EB1 family Mal3 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAP8A3.07cphospho-2-dehydro-3-deoxyheptonate aldolase (predicted) Positive GeneticPMID:22681890
alp14TOG ortholog Alp14 Negative GeneticPMID:18818364
sol1SWI/SNF complex subunit Sol1 Positive GeneticPMID:22681890
rok1ATP-dependent RNA helicase Rok1 (predicted) Negative GeneticPMID:18818364
erf2palmitoyltransferase Erf2 (predicted) Negative GeneticPMID:22681890
spd1ribonucleotide reductase (RNR) inhibitor Positive GeneticPMID:22681890
SPAC6G9.15csequence orphan Negative GeneticPMID:22681890
med13mediator complex subunit Srb9 Negative GeneticPMID:18818364
set1histone lysine methyltransferase Set1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
myo51myosin type V Negative GeneticPMID:22681890
SPCP20C8.02cS. pombe specific UPF0321 family protein 1 Positive GeneticPMID:22681890
nup124nucleoporin Nup124 Positive GeneticPMID:22681890
tup11transcriptional corepressor Tup11 Negative GeneticPMID:22681890
SPBC16C6.05mitochondrial translation initiation factor (predicted) Negative GeneticPMID:18818364
adh4alcohol dehydrogenase Adh4 Positive GeneticPMID:22681890
omh5alpha-1,2-mannosyltransferase Omh5 (predicted) Positive GeneticPMID:22681890
SPCC1020.08wybutosine biosynthesis protein Tyw1 (predicted) Positive GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:18818364
SPAC18B11.03cN-acetyltransferase (predicted) Positive GeneticPMID:22681890
gsk3serine/threonine protein kinase Gsk3 Positive GeneticPMID:22681890
get1GET complex subunit Get1 (predicted) Negative GeneticPMID:22681890
aca1L-azetidine-2-carboxylic acid acetyltransferase Aca1 Positive GeneticPMID:22681890
slx9ribosome biogenesis protein Slx9 (predicted) Negative GeneticPMID:18818364
gcd10tRNA (m1A) methyltransferase, translation initiation factor eIF-3 gamma subunit Gcd10 (predicted) Negative GeneticPMID:22681890
far8SIP/FAR complex striatin subunit, Far8/Csc3 Negative GeneticPMID:22681890
par1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:18818364
rad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC328.01ckaryopherin (predicted) Negative GeneticPMID:18818364
SPBC839.03cneddylation protein Dcn1 (predicted) Negative GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:18818364
ire1serine/threonine protein kinase, sensor for unfolded proteins in the ER Ire1 Negative GeneticPMID:22681890
ppk30Ark1/Prk1 family protein kinase Ppk30 Positive GeneticPMID:18818364
ilv1acetolactate synthase catalytic subunit Negative GeneticPMID:22681890
ssr3SWI/SNF and RSC complex subunit Ssr3 Negative GeneticPMID:18818364
ies2Ino80 complex subunit Ies2 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
swi3replication fork protection complex subunit Swi3 Negative GeneticPMID:18818364
slx1structure-specific endonuclease catalytic subunit Positive GeneticPMID:18818364
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Synthetic LethalityPMID:21211723
tsc2tuberin Negative GeneticPMID:22681890
SPAC25B8.07chypoxia induced family protein Positive GeneticPMID:18818364
ell1RNA polymerase II transcription elongation factor SpELL Negative GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
amo1nuclear rim protein Amo1 Negative GeneticPMID:18818364
cid12poly(A) polymerase Cid12 Negative GeneticPMID:18818364
ccr4CCR4-Not complex subunit Ccr4 (predicted) Positive GeneticPMID:18818364
scs7sphingosine hydroxylase Scs7 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPAC1399.04curacil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
klp6kinesin-like protein Klp6 Negative GeneticPMID:18818364
nup61nucleoporin Nup61 Negative GeneticPMID:18818364
SPBC16H5.12cconserved fungal protein Positive GeneticPMID:22681890
SPBC29A10.16ccytochrome b5 (predicted) Negative GeneticPMID:22681890
sum2G2/M transition checkpoint protein Sum2 Negative GeneticPMID:22681890
srb11cyclin CycC, Srb mediator subunit Srb11 Negative GeneticPMID:18818364
gcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Positive GeneticPMID:18818364
SPCC736.07cunconventional prefoldin involved in translation initiation (predicted) Positive GeneticPMID:22681890
SPAC694.04cconserved eukaryotic protein Positive GeneticPMID:22681890
cdc25M phase inducer phosphatase Cdc25 Synthetic LethalityPMID:15121850
sgf29SAGA complex subunit Sgf29 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
SPCC63.14conserved fungal protein Negative GeneticPMID:22681890
mit1SHREC complex subunit Mit1 Phenotypic EnhancementPMID:21211723
lsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative GeneticPMID:18818364
rpt419S proteasome regulatory subunit Rpt4 (predicted) Negative GeneticPMID:22681890
rsc4RSC complex subunit Rsc4 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ufd2ubiquitin-protein ligase E4 (predicted) Negative GeneticPMID:18818364
pcf3CAF assembly factor (CAF-1) complex subunit C, Pcf3 Negative GeneticPMID:18818364
arp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:18818364
rik1silencing protein Rik1 Negative GeneticPMID:18818364
oca2serine/threonine protein kinase Oca2 Positive GeneticPMID:22681890
SPCC1281.07cglutathione S-transferase (predicted) Positive GeneticPMID:22681890
eri1double-strand siRNA ribonuclease Eri1 Negative GeneticPMID:22681890
yaf9YEATS family histone acetyltransferase subunit Yaf9 Negative GeneticPMID:18818364
mkh1MEK kinase (MEKK) Mkh1 Negative GeneticPMID:22681890
cay1cactin, spliceosome complex subunit (predicted) Negative GeneticPMID:18818364
hip4histone promoter control protein Hip4 Positive GeneticPMID:18818364
hrp1ATP-dependent DNA helicase Hrp1 Negative GeneticPMID:18818364
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
swi6HP1 family chromodomain protein Swi6 Affinity Capture-WesternPMID:21211723
cia1histone chaperone Cia1 Affinity Capture-MSPMID:21211723
Co-crystal StructurePMID:18334479
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
slm9hira protein Slm9 Affinity Capture-WesternPMID:15121850
Co-localizationPMID:16428807
Affinity Capture-MS
Affinity Capture-MSPMID:20976105
hip3HIRA interacting protein Hip3 Affinity Capture-MSPMID:16428807
Affinity Capture-Western
mst1KAT5 family histone acetyltransferase Mst1 Two-hybridPMID:18505873
hip4histone promoter control protein Hip4 Affinity Capture-WesternPMID:20976105
Contact Curators
External References
Database Identifier Description
NBRP SPBC31F10.13c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC31F10.13c Retrieval of eukaryotic orthologs
BioGrid SPBC31F10.13c BioGRID Interaction Datasets
Bähler Lab SPBC31F10.13c Cell Cycle Expression Profile
Bähler Lab SPBC31F10.13c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC31F10.13c Pheromone response/mating expression profiles
Bähler Lab SPBC31F10.13c Environmental stress expression profiles
Bähler Lab SPBC31F10.13c Bähler Lab Transcriptome Viewer
Cyclebase SPBC31F10.13c Cell Cycle Data
PInt SPBC31F10.13c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC31F10.13c Entrez Gene
EntrezGene2540219hira protein, histone chaperone Hip1
Uniprot_genenameHIP1
WikiGene2540219hira protein, histone chaperone Hip1
UniProtKB/SwissProtP87314Protein hir1
ModBaseP87314Database of comparative protein structure models
Pfam Protein DomainsP87314Pfam Domain Arrangement
RefSeq PeptideNP_596575hira protein, histone chaperone Hip1
RefSeq mRNANM_001022496972h- hira protein, histone chaperone Hip1 (hip1), mRNA
European Nucleotide ArchiveBAA87296ENA Protein Mapping
European Nucleotide ArchiveCAB10089ENA Protein Mapping
SPD / RIKEN47/47F10Orfeome Localization Data
UniParcUPI000012C734UniProt Archive

Literature for hip1
Contact Curators

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013