omh5 (SPBC32H8.08c)

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Gene Standard Nameomh5 Characterisation Statusbiological role inferred
Systematic IDSPBC32H8.08c Feature Typeprotein coding
Synonymspi016, SPACTOKYO_453.20 Name DescriptionO-glycoside alpha1,2-Mannosyltransferase Homolog
Productalpha-1,2-mannosyltransferase Omh5 (predicted) Product Size421aa, 49.92 kDa
Genomic Location Chromosome II, 1467431-1465811 (1621nt); CDS:1467431-1465811 (1621nt)

Ensembl Gene Location
  1. fcf1
  2. SPBC32H8.05
  3. mug93-antisense-1
  4. mug93
  5. git5
  6. omh5
  7. snR95
  8. wdr8
  9. cdk9
  10. mei4
GO Molecular Function
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Term NameCount
alpha-1,2-mannosyltransferase activity9
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process

GO Slim Terms

cell wall organization or biogenesis carbohydrate derivative metabolic process protein glycosylation


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Term NameCount
cell wall mannoprotein biosynthetic process10
Annotation ExtensionEvidenceWith/FromReference
protein mannosylation10
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
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Term NameCount
cytosol2298
Annotation ExtensionEvidenceWith/FromReference
Golgi membrane56
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

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Term NameGenotypesCount
sensitive to hygromycin Bomh5Δ16
viable vegetative cell populationomh5Δ3862

Cell Phenotype

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Term NameGenotypesCount
viable vegetative cell with normal cell morphologyomh5Δ3103
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons1467431..1467311, 1467057..1466138, 1466035..1465811
Intron1467310..1467058, 1466137..1466036
mRNA1467431..1465811
CDS1467431..1467311, 1467057..1466138, 1466035..1465811
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01793 Pfam IPR002685 Glycosyl transferase, family 15 82 378 6
TMhelix TMHMM 20 42 950
PTHR31121 HMMPANTHER IPR002685 Glycosyl transferase, family 15 301 421 6
PTHR31121:SF2 HMMPANTHER 301 421 2
PTHR31121:SF2 HMMPANTHER 12 284 2
PTHR31121 HMMPANTHER IPR002685 Glycosyl transferase, family 15 12 284 6
3.90.550.10 Gene3D IPR029044 Nucleotide-diphospho-sugar transferases 77 416 19
SSF53448 SuperFamily IPR029044 Nucleotide-diphospho-sugar transferases 73 274 27
SSF53448 SuperFamily IPR029044 Nucleotide-diphospho-sugar transferases 304 416 27
PIRSF018153 PIRSF IPR002685 Glycosyl transferase, family 15 1 419 5

View domain organization at Pfam

Protein Properties

Ave. residue weight 118.57 Da
Charge 1.50
Codon Adaptation Index 0.42
Isoelectric point 6.69
Molecular weight 49.92 kDa
Number of residues 421
Sequence
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Gene Expression
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Quantitative Gene Expression

View graphical display of gene expression data for omh5 (SPBC32H8.08c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
868.96during GO:0072690PECO:0000126,
PECO:0000005		population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.8during GO:0072690PECO:0000126,
PECO:0000005		population wideexperimental evidencePMID:23101633
0.64during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000126,
PECO:0000005		population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi only552
conserved in fungi4608
conserved in eukaryotes4516
Orthologs
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Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPBC32H8.08c into the Query Builder
View these interactions in esyN

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Gene Product Evidence Reference
positive genetic interaction withhip1hira protein, histone chaperone Hip1 Positive GeneticPMID:22681890
positive genetic interaction withtif38translation initiation factor eIF3h (p40) Positive GeneticPMID:22681890
positive genetic interaction witheif21translation initiation factor eIF2A (predicted) Positive GeneticPMID:22681890
positive genetic interaction withcdt2WD repeat protein Cdt2 Positive GeneticPMID:22681890
positive genetic interaction withdsc3Golgi Dsc E3 ligase complex subunit Dsc3 Positive GeneticPMID:21504829
positive genetic interaction withcid12poly(A) polymerase Cid12 Positive GeneticPMID:22681890
positive genetic interaction withmmb1mitochondrial microtubule binder Mmb1 Positive GeneticPMID:22681890
positive genetic interaction withurk1uridine kinase/uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
positive genetic interaction witharp42SWI/SNF and RSC complex subunit Arp42 Positive GeneticPMID:22681890
positive genetic interaction withphp5CCAAT-binding factor complex subunit Php5 Positive GeneticPMID:22681890
positive genetic interaction withssm4dynactin microtubule-binding subunit, p150-Glued Ssm4 Positive GeneticPMID:22681890
negative genetic interaction withSPCC16C4.106-phosphogluconolactonase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withatg6autophagy associated beclin family protein Atg6 Negative GeneticPMID:22681890
negative genetic interaction withrga2RhoGAP, GTPase activating protein Rga2 Negative GeneticPMID:22681890
External References
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Database Identifier Description
NBRP SPBC32H8.08c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC32H8.08c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC32H8.08c BioGRID Interaction Datasets
Expression Viewer SPBC32H8.08c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC32H8.08c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC32H8.08c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC32H8.08c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC32H8.08c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC32H8.08c Transcriptome Viewer (Bähler Lab)
GEO SPBC32H8.08c GEO profiles
PInt SPBC32H8.08c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC32H8.08c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC32H8.08c Fission yeast phenotypic data & analysis
Cyclebase SPBC32H8.08c.1 Cell Cycle Data
SPD / RIKEN49/49B08Orfeome Localization Data
UniProtKB/SwissProtQ96WW1O-glycoside alpha-1,2-mannosyltransferase homolog 5
ModBaseQ96WW1Database of comparative protein structure models
STRINGQ96WW1Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595614alpha-1,2-mannosyltransferase Omh5 (predicted)
RefSeq mRNANM_001021509972h- alpha-1,2-mannosyltransferase Omh5 (predicted) (omh5), mRNA
European Nucleotide ArchiveBAA21393.2ENA Protein Mapping
European Nucleotide ArchiveBAA21395.1ENA Protein Mapping
European Nucleotide ArchiveCAC37498.2ENA Protein Mapping
UniParcUPI0001B0629AUniProt Archive

Literature for omh5
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Release Version: PomBase:30_62 - 30 Jan 2017