rrn7 (SPBC336.09c)


Gene Standard Namerrn7 Characterisation Statuspublished
Systematic IDSPBC336.09c Feature Typeprotein coding
Synonyms Name Description
ProductRNA polymerase I core factor complex subunit Rrn7 Product Size537aa, 61.91 kDa
Genomic Location Chromosome II, 2758582-2756276 (2307nt); CDS:2757982-2756305 (1678nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
DNA binding372
Annotation ExtensionEvidenceWith/FromReference
metal ion binding750
Annotation ExtensionEvidenceWith/FromReference
protein binding863
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
transcription from RNA polymerase I promoter32
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2306
Annotation ExtensionEvidenceWith/FromReference
nucleus2692
Annotation ExtensionEvidenceWith/FromReference
RNA polymerase I core factor complex3
Annotation ExtensionEvidenceWith/FromReference
RNA polymerase I transcription factor complex9
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationrrn7Δ1453

Cell Phenotype

Term NameGenotypesCount
abnormal mitotic cell cyclerrn7Δ858
inviable elongated vegetative cellrrn7Δ416
inviable vegetative cell, abnormal cell shape, normal cell sizerrn7Δ199
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2758582..2757872, 2757807..2756276
Intron2757871..2757808
5' UTR2758582..2757983PMID:21511999
3' UTR2756304..2756276PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF11781 Pfam IPR021752 Transcription initiation factor Rrn7 4 37 1
PTHR31576:SF2 HMMPANTHER 1 421 1
PTHR31576 HMMPANTHER 1 421 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.29 Da
Charge -0.50
Codon Adaptation Index 0.39
Isoelectric point 6.45
Molecular weight 61.91 kDa
Number of residues 537
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for rrn7 (SPBC336.09c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
74.94during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.2during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
0.56during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi only618
conserved in fungi4605
conserved in eukaryotes4515
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPBC336.09c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
binds DNA-binding domain construct withcaf4CCR4-Not complex subunit Caf4/Mdv1 (predicted) Two-hybridPMID:26771498
co-fractionates withrrn11RNA polymerase I transcription factor subunit Rrn11 (predicted) Co-fractionationPMID:12095692
External References
Database Identifier Description
NBRP SPBC336.09c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC336.09c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC336.09c BioGRID Interaction Datasets
Expression Viewer SPBC336.09c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC336.09c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC336.09c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC336.09c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC336.09c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC336.09c Transcriptome Viewer (Bähler Lab)
GEO SPBC336.09c GEO profiles
PInt SPBC336.09c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC336.09c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC336.09c Fission yeast phenotypic data & analysis
Cyclebase SPBC336.09c.1 Cell Cycle Data
SPD / RIKEN35/35B03Orfeome Localization Data
UniProtKB/SwissProtQ9UST5RNA polymerase I-specific transcription initiation factor rrn7
ModBaseQ9UST5Database of comparative protein structure models
STRINGQ9UST5Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596129RNA polymerase I upstream activation factor complex subunit Rrn7
RefSeq mRNANM_001022047972h- RNA polymerase I upstream activation factor complex subunit Rrn7 (rrn7), mRNA

Literature for rrn7

Search: Europe PMC or PubMed

Release Version: PomBase:30_58 - 11 Mar 2016