rrn7 (SPBC336.09c)

Gene Standard Namerrn7 Characterisation Statuspublished
Systematic IDSPBC336.09c Feature Typeprotein coding
Synonyms Name Description
ProductRNA polymerase I core factor complex subunit Rrn7 Product Size537aa, 61.91 kDa
Genomic Location Chromosome II, 2758582-2756276 (2307nt); CDS:2757982-2756305 (1678nt)

Ensembl Gene Location
GO Molecular Function
GO Biological Process
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
RNA polymerase I core factor complex3
Annotation ExtensionEvidenceWith/FromReference
RNA polymerase I transcription factor complex9
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationrrn7Δ1468

Cell Phenotype

Term NameGenotypesCount
abnormal mitotic cell cyclerrn7Δ903
decreased protein phosphorylation during vegetative growth105
affecting substrate rrn7, affecting activity of cka1T67A (T67A)
increased transcription during vegetative growth55
affecting rps2202rrn7+
affecting trz2rrn7+
inviable elongated vegetative cellrrn7Δ440
inviable vegetative cell, abnormal cell shape, normal cell sizerrn7Δ199
normal DNA binding18
affecting substrate SO:0001848, affecting activity of rrn7T67A (T67A)
normal transcription during vegetative growth13
affecting trz1rrn7+
affecting rps2502rrn7+
Target Of
FYPO affected by mutation in rrn7 RNA polymerase I core factor complex subunit Rrn7
GO substrate of cka1 serine/threonine protein kinase Cka1
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2758582..2757872, 2757807..2756276
5' UTR2758582..2757983PMID:21511999
CDS2757982..2757872, 2757807..2756305
3' UTR2756304..2756276PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF11781 Pfam IPR021752 Transcription initiation factor Rrn7, Zinc-finger 5 38 1
PTHR31576 HMMPANTHER 1 421 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.29 Da
Charge -0.50
Codon Adaptation Index 0.39
Isoelectric point 6.45
Molecular weight 61.91 kDa
Number of residues 537

Protein Modifications

Term NameResidueCount
O-phospho-L-threonine 1087
added by cka1T67
Annotation ExtensionEvidenceResidueReference
added by cka1 IDA T67 PMID:25410910
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for rrn7 (SPBC336.09c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
74.94during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.2during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
0.56during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3087
conserved in fungi4608
conserved in eukaryotes4516
conserved in metazoa3498
conserved in vertebrates3473

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Load genes that interact physically with SPBC336.09c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity capturesckb1CK2 family regulatory subunit Ckb1 Affinity Capture-WesternPMID:25410910
affinity capturescka1serine/threonine protein kinase Cka1 Affinity Capture-WesternPMID:25410910
binds DNA-binding domain construct withcaf4CCR4-Not complex subunit Caf4/Mdv1 (predicted) Two-hybridPMID:26771498
co-fractionates withrrn11RNA polymerase I transcription factor subunit Rrn11 (predicted) Co-fractionationPMID:12095692
External References
Database Identifier Description
NBRP SPBC336.09c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC336.09c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC336.09c BioGRID Interaction Datasets
Expression Viewer SPBC336.09c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC336.09c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC336.09c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC336.09c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC336.09c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC336.09c Transcriptome Viewer (Bähler Lab)
GEO SPBC336.09c GEO profiles
PInt SPBC336.09c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC336.09c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC336.09c Fission yeast phenotypic data & analysis
Cyclebase SPBC336.09c.1 Cell Cycle Data
SPD / RIKEN35/35B03Orfeome Localization Data
UniProtKB/SwissProtQ9UST5RNA polymerase I-specific transcription initiation factor rrn7
ModBaseQ9UST5Database of comparative protein structure models
STRINGQ9UST5Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596129RNA polymerase I upstream activation factor complex subunit Rrn7
RefSeq mRNANM_001022047972h- RNA polymerase I upstream activation factor complex subunit Rrn7 (rrn7), mRNA
European Nucleotide ArchiveCAB58161.1ENA Protein Mapping
UniParcUPI0000134A5AUniProt Archive

Literature for rrn7

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017