rrn7 (SPBC336.09c)


Gene Standard Namerrn7 Characterisation Statuspublished
Systematic IDSPBC336.09c Feature Typeprotein coding
Synonyms Name Description
ProductRNA polymerase I core factor complex subunit Rrn7 Product Size537aa, 61.91 kDa
Genomic Location Chromosome II, 2758582-2756276 (2307nt); CDS:2757982-2756305 (1678nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003677DNA bindingIEAUniProtKB-KW:KW-0238GO_REF:0000037385
GO:0046872metal ion bindingIEAUniProtKB-KW:KW-0479GO_REF:0000037749
GO:0005515protein bindingIPIrrn11PMID:12095692861
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006360transcription from RNA polymerase I promoterIDAPMID:1209569229
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0070860RNA polymerase I core factor complexISOSGD:S000003562GO_REF:00000243
GO:0000120RNA polymerase I transcription factor complexIDAPMID:120956929
GO:0005829cytosolIDAPMID:168233722316
GO:0005634nucleusIDAPMID:168233722740
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopyrrn7ΔNullPMID:204732891315
Microscopyrrn7ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000059abnormal mitotic cell cycleMicroscopyrrn7ΔNullPECO:0000004, PECO:0000137PMID:23697806624
FYPO:0001490inviable elongated vegetative cell381
penetrance FYPO_EXT:0000003Microscopyrrn7ΔNullPECO:0000005, PECO:0000137PMID:23697806
FYPO:0001511inviable vegetative cell, abnormal cell shape, normal cell size199
expressivity FYPO_EXT:0000003
penetrance FYPO_EXT:0000001
Microscopyrrn7ΔNullPECO:0000137, PECO:0000005PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
127585822757872
227578072756276

UTRs

Region Coordinates Reference
five_prime_UTR2758582..2757983PMID:21511999
three_prime_UTR2756304..2756276PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF11781 Pfam IPR021752 Transcription initiation factor Rrn7 4 37 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.29 Da
Charge -0.50
Isoelectric point 6.45
Molecular weight 61.91 kDa
Number of residues 537
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
74.94during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
1.2during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
0.56during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi only603
conserved in fungi4569
conserved in eukaryotes4482
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
rrn11RNA polymerase I transcription factor subunit Rrn11 (predicted) Co-fractionationPMID:12095692
External References
Database Identifier Description
NBRP SPBC336.09c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC336.09c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC336.09c BioGRID Interaction Datasets
Expression Viewer SPBC336.09c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC336.09c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC336.09c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC336.09c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC336.09c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC336.09c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC336.09c Cell Cycle Data
GEO SPBC336.09c GEO profiles
PInt SPBC336.09c Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2540236RNA polymerase I upstream activation factor complex subunit Rrn7
EntrezGene2540236RNA polymerase I upstream activation factor complex subunit Rrn7
SPD / RIKEN35/35B03Orfeome Localization Data
UniProtKB/SwissProtQ9UST5RNA polymerase I-specific transcription initiation factor rrn7
ModBaseQ9UST5Database of comparative protein structure models
STRINGQ9UST5Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596129RNA polymerase I upstream activation factor complex subunit Rrn7
RefSeq mRNANM_001022047972h- RNA polymerase I upstream activation factor complex subunit Rrn7 (rrn7), mRNA
European Nucleotide ArchiveCAB58161ENA Protein Mapping
European Nucleotide ArchiveCAB58161.1ENA Protein Mapping
UniParcUPI0000134A5AUniProt Archive

Literature for rrn7

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014