vps52 (SPBC336.11)


Gene Standard Namevps52 Characterisation Statusbiological_role_inferred
Systematic IDSPBC336.11 Feature Typeprotein coding
Synonyms Name Description
ProductGARP complex subunit Vps52 (predicted) Product Size508aa, 58.38 kDa
Genomic Location Chromosome II, 2759472-2761211 (1740nt); CDS:2759639-2761165 (1527nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006896Golgi to vacuole transportISOSGD:S000002892GO_REF:000002418
GO:0030029actin filament-based processISOSGD:S000002892GO_REF:000002499
GO:0006886intracellular protein transportICGO:0042147GO_REF:0000001326
GO:0042147retrograde transport, endosome to GolgiISOSGD:S000002892GO_REF:000002423
GO:0016192vesicle-mediated transportISOSGD:S000002892GO_REF:0000024298
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0000938GARP complexISOSGD:S000002892GO_REF:00000244
GO:0005794Golgi apparatusIDAPMID:16823372355
GO:0016020membraneIEAUniProtKB-KW:KW-0472GO_REF:00000371450
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopyvps52ΔNullPECO:0000005, PECO:0000137PMID:236978061337
Microscopyvps52ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000054abnormal microtubule cytoskeleton organizationMicroscopynot recorded (overexpression)PMID:1579792551
FYPO:0002148inviable after spore germination, multiple cell divisions, abnormal morphology187
expressivity FYPO_EXT:0000003Microscopyvps52ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
127594722761211
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04129 Pfam IPR007258 Vps52/Sac2 1 508 1
PTHR14190 HMMPANTHER IPR007258 Vps52/Sac2 18 507 1
PTHR14190:SF4 HMMPANTHER 18 507 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.93 Da
Charge 6.50
Isoelectric point 7.99
Molecular weight 58.38 kDa
Number of residues 508
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
878during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
1076during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
NDduring GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
843during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.39during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4599
conserved in eukaryotes4514
conserved in metazoa3428
conserved in vertebrates3402
conserved in eukaryotes only2498
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPBC336.11 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC336.11 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC336.11 BioGRID Interaction Datasets
Expression Viewer SPBC336.11 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC336.11 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC336.11 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC336.11 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC336.11 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC336.11 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC336.11 Cell Cycle Data
GEO SPBC336.11 GEO profiles
PInt SPBC336.11 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC336.11 Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN44/44H03Orfeome Localization Data
UniProtKB/SwissProtQ9UST3Vacuolar protein sorting-associated protein 52
ModBaseQ9UST3Database of comparative protein structure models
STRINGQ9UST3Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596131GARP complex subunit Vps52 (predicted)
RefSeq mRNANM_001022049972h- GARP complex subunit Vps52 (predicted) (vps52), mRNA
European Nucleotide ArchiveCAB58163.1ENA Protein Mapping
UniParcUPI000006A056UniProt Archive

Literature for vps52

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014