vps52 (SPBC336.11)

Gene Standard Namevps52 Characterisation Statusbiological role inferred
Systematic IDSPBC336.11 Feature Typeprotein coding
Synonyms Name Description
ProductGARP complex subunit Vps52 (predicted) Product Size508aa, 58.38 kDa
Genomic Location Chromosome II, 2759472-2761211 (1740nt); CDS:2759639-2761165 (1527nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
actin filament-based process105
Annotation ExtensionEvidenceWith/FromReference
Golgi to vacuole transport18
Annotation ExtensionEvidenceWith/FromReference
intracellular protein transport336
Annotation ExtensionEvidenceWith/FromReference
retrograde transport, endosome to Golgi22
Annotation ExtensionEvidenceWith/FromReference
vesicle-mediated transport323
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
GARP complex4
Annotation ExtensionEvidenceWith/FromReference
Golgi apparatus357
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationvps52Δ1443

Cell Phenotype

Term NameGenotypesCount
abnormal microtubule cytoskeleton organization during vegetative growthvps52+ (wild type)296
inviable after spore germination, multiple cell divisions, abnormal morphologyvps52Δ197
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR2759472..2759638PMID:21511999
3' UTR2761166..2761211PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04129 Pfam IPR007258 Vps52 1 508 1
PTHR14190 HMMPANTHER IPR007258 Vps52 18 507 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.93 Da
Charge 6.50
Codon Adpatation Index 0.40
Isoelectric point 7.99
Molecular weight 58.38 kDa
Number of residues 508
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
878during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
1076during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
843during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
0.39during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3090
conserved in fungi4604
conserved in eukaryotes4514
conserved in metazoa3421
conserved in vertebrates3396
conserved in eukaryotes only2503

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPBC336.11 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC336.11 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC336.11 BioGRID Interaction Datasets
Expression Viewer SPBC336.11 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC336.11 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC336.11 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC336.11 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC336.11 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC336.11 Transcriptome Viewer (Bähler Lab)
GEO SPBC336.11 GEO profiles
PInt SPBC336.11 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC336.11 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC336.11 Fission yeast phenotypic data & analysis
Cyclebase SPBC336.11.1 Cell Cycle Data
SPD / RIKEN44/44H03Orfeome Localization Data
UniProtKB/SwissProtQ9UST3Vacuolar protein sorting-associated protein 52
ModBaseQ9UST3Database of comparative protein structure models
STRINGQ9UST3Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596131GARP complex subunit Vps52 (predicted)
RefSeq mRNANM_001022049972h- GARP complex subunit Vps52 (predicted) (vps52), mRNA
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveCAB58163ENA Protein Mapping
European Nucleotide ArchiveCAB58163.1ENA Protein Mapping
UniParcUPI000006A056UniProt Archive

Literature for vps52

Search: Europe PMC or PubMed

Release Version: PomBase:28_55 - 09 Sep 2015