SPBC3E7.11c


Gene Standard NameUnassigned Characterisation Statusconserved_unknown
Systematic IDSPBC3E7.11c Feature Typeprotein coding
Synonyms Name Description
ProductDNAJ protein Caj1/Djp1-type (predicted) Product Size355aa, 40.53 kDa
Genomic Location Chromosome II, 2681786-2680226 (1561nt); CDS:2681669-2680433 (1237nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0030544Hsp70 protein bindingISMPFAM:PF00226GO_REF:000000126
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006457protein foldingNASGO_REF:0000051111
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722316
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopySPBC3E7.11cΔNullPECO:0000005, PECO:0000137PMID:236978063760
MicroscopySPBC3E7.11cΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3086
penetrance FYPO_EXT:0000001MicroscopySPBC3E7.11cΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
126817862681581
226815392681467
326813382680226

UTRs

Region Coordinates Reference
five_prime_UTR2681786..2681670PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF14308 Pfam IPR026894 DNAJ-containing protein, X-domain 150 350 2
PF00226 Pfam IPR001623 DnaJ domain 9 72 24
SM00271 SMART IPR001623 DnaJ domain 8 67 25
PS00636 Prosite Patterns IPR018253 DnaJ domain, conserved site 52 71 14
PS50076 Prosite Profiles IPR001623 DnaJ domain 9 75 24
PTHR24076 HMMPANTHER 3 119 7
1.10.287.110 Gene3D IPR001623 DnaJ domain 3 96 26
SSF46565 SuperFamily IPR001623 DnaJ domain 7 102 25
Coil ncoils Rabaptin coiled-coil domain 127 148 968
PR00625 PRINTS IPR001623 DnaJ domain 11 29 21
PR00625 PRINTS IPR001623 DnaJ domain 67 86 21
PR00625 PRINTS IPR001623 DnaJ domain 29 44 21
PR00625 PRINTS IPR001623 DnaJ domain 47 67 21

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.17 Da
Charge -8.00
Isoelectric point 4.93
Molecular weight 40.53 kDa
Number of residues 355
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
11101during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
927.09during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
9194during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
9415during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
1.7during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
0.51during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4569
conserved in eukaryotes4482
conserved in eukaryotes only2487
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
prp43ATP-dependent RNA helicase Prp43 Negative GeneticPMID:22681890
rsv2transcription factor Rsv2 Negative GeneticPMID:22681890
vps17retromer complex subunit Vps17 Negative GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Negative GeneticPMID:22681890
SPAC1B3.02ctranscription elongation factor, Elf1 family (predicted) Positive GeneticPMID:22681890
sty1MAP kinase Sty1 Negative GeneticPMID:22681890
dad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
fan1Fanconi-associated nuclease Fan1 Synthetic RescuePMID:24192486
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPBC3E7.11c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC3E7.11c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC3E7.11c BioGRID Interaction Datasets
Expression Viewer SPBC3E7.11c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC3E7.11c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC3E7.11c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC3E7.11c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC3E7.11c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC3E7.11c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC3E7.11c Cell Cycle Data
GEO SPBC3E7.11c GEO profiles
PInt SPBC3E7.11c Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2540676DNAJ protein Caj1/Djp1-type
EntrezGene2540676DNAJ protein Caj1/Djp1-type
SPD / RIKEN22/22C03Orfeome Localization Data
UniProtKB/SwissProtO59731Uncharacterized J domain-containing protein C3E7.11c
ModBaseO59731Database of comparative protein structure models
STRINGO59731Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596098DNAJ protein Caj1/Djp1-type
RefSeq mRNANM_001022014972h- DNAJ protein Caj1/Djp1-type (SPBC3E7.11c), mRNA
European Nucleotide ArchiveCAA19014ENA Protein Mapping
European Nucleotide ArchiveCAA19014.1ENA Protein Mapping
UniParcUPI000006BAD1UniProt Archive

Literature for SPBC3E7.11c

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014