SPBC3E7.11c


Gene Standard NameUnassigned Characterisation Statusconserved_unknown
Systematic IDSPBC3E7.11c Feature Typeprotein coding
Synonyms Name Description
ProductDNAJ protein Caj1/Djp1-type (predicted) Product Size355aa, 40.53 kDa
Genomic Location Chromosome II, 2681786-2680226 (1561nt); CDS:2681669-2680433 (1237nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
Hsp70 protein binding26
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process

GO Slim Terms

protein folding


Term NameCount
protein folding103
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2314
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationSPBC3E7.11cΔNull3795

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologySPBC3E7.11cΔNull3093
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2681786..2681581, 2681539..2681467, 2681338..2680226
mRNA2681786..2680226
5' UTR2681786..2681670PMID:21511999
CDS2681669..2681581, 2681539..2681467, 2681338..2680433
3' UTR2680432..2680226AU011790
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00226 Pfam IPR001623 DnaJ domain 9 72 24
PF14308 Pfam IPR026894 DNAJ-containing protein, X-domain 150 350 2
SM00271 SMART IPR001623 DnaJ domain 8 67 23
PS50076 Prosite Profiles IPR001623 DnaJ domain 9 75 24
PS00636 Prosite Patterns IPR018253 DnaJ domain, conserved site 52 71 14
PTHR24076 HMMPANTHER 3 119 7
1.10.287.110 Gene3D IPR001623 DnaJ domain 3 96 26
SSF46565 SuperFamily IPR001623 DnaJ domain 7 102 25
Coil ncoils Rabaptin coiled-coil domain 127 148 968
PR00625 PRINTS IPR001623 DnaJ domain 29 44 21
PR00625 PRINTS IPR001623 DnaJ domain 11 29 21
PR00625 PRINTS IPR001623 DnaJ domain 67 86 21
PR00625 PRINTS IPR001623 DnaJ domain 47 67 21

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.17 Da
Charge -8.00
Isoelectric point 4.93
Molecular weight 40.53 kDa
Number of residues 355
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
11101during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
9194during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
9415during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
927.09during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.7during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.51during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4604
conserved in eukaryotes4516
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withdad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
synthetically rescuesfan1Fanconi-associated nuclease Fan1 Synthetic RescuePMID:24192486
negative genetic interaction withprp43ATP-dependent RNA helicase Prp43 Negative GeneticPMID:22681890
negative genetic interaction withptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
negative genetic interaction withrsv2transcription factor Rsv2 Negative GeneticPMID:22681890
positive genetic interaction withSPAC1B3.02ctranscription elongation factor, Elf1 family (predicted) Positive GeneticPMID:22681890
negative genetic interaction withsty1MAP kinase Sty1 Negative GeneticPMID:22681890
negative genetic interaction withtom70mitochondrial TOM complex subunit Tom70 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withvps17retromer complex subunit Vps17 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPBC3E7.11c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC3E7.11c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC3E7.11c BioGRID Interaction Datasets
Expression Viewer SPBC3E7.11c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC3E7.11c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC3E7.11c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC3E7.11c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC3E7.11c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC3E7.11c Transcriptome Viewer (Bähler Lab)
GEO SPBC3E7.11c GEO profiles
PInt SPBC3E7.11c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC3E7.11c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC3E7.11c Fission yeast phenotypic data & analysis
Cyclebase SPBC3E7.11c.1 Cell Cycle Data
SPD / RIKEN22/22C03Orfeome Localization Data
UniProtKB/SwissProtO59731Uncharacterized J domain-containing protein C3E7.11c
ModBaseO59731Database of comparative protein structure models
STRINGO59731Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596098DNAJ protein Caj1/Djp1-type (predicted)
RefSeq mRNANM_001022014972h- DNAJ protein Caj1/Djp1-type (predicted) (SPBC3E7.11c), mRNA
European Nucleotide ArchiveCAA19014.1ENA Protein Mapping
UniParcUPI000006BAD1UniProt Archive

Literature for SPBC3E7.11c

Search: Europe PMC or PubMed

Release Version: PomBase:26_51 - 07 Apr 2015