meu18 (SPBC409.11)


Gene Standard Namemeu18 Characterisation StatusSchizosaccharomyces specific family
Systematic IDSPBC409.11 Feature Typeprotein coding
Synonyms Name DescriptionMeiotic Expression Upregulated
ProductSchizosaccharomyces specific protein Meu18 Product Size553aa, 64.79 kDa
Genomic Location Chromosome II, 1158533-1160295 (1763nt); CDS:1158594-1160255 (1662nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0051321meiotic cell cycleIEAUniProtKB-KW:KW-0469GO_REF:0000037437
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005737cytoplasmIDAPMID:168233724205
GO:0005635nuclear envelopeIDAPMID:16823372137
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopymeu18ΔNullPMID:204732893759
Microscopymeu18ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000478normal meiosisMicroscopymeu18ΔNullPMID:16169489139
FYPO:0002177viable vegetative cell with normal cell morphology3089
penetrance FYPO_EXT:0000001Microscopymeu18ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
111585331160295

UTRs

Region Coordinates Reference
five_prime_UTR1158533..1158593PMID:20118936
three_prime_UTR1160256..1160295PMID:20118936
five_prime_UTR1158533..1158593PMID:18641648
three_prime_UTR1160256..1160295PMID:18641648
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
TMhelix TMHMM 21 43 959
Coil ncoils Rabaptin coiled-coil domain 441 462 968

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0000418signal_peptide279
SO:0001528nuclear_localization_signalPMID:1137615120

Protein Properties

Ave. residue weight 117.17 Da
Charge 10.00
Isoelectric point 8.18
Molecular weight 64.79 kDa
Number of residues 553
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelincreased during GO:0051321experimental evidencePMID:16303567
increased during GO:0051321experimental evidencePMID:11376151

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.3during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.36during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
Schizosaccharomyces specific222
Orthologs

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
xap5xap-5-like protein Negative GeneticPMID:24957674
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
External References
Database Identifier Description
NBRP SPBC409.11 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC409.11 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC409.11 BioGRID Interaction Datasets
Expression Viewer SPBC409.11 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC409.11 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC409.11 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC409.11 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC409.11 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC409.11 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC409.11 Cell Cycle Data
GEO SPBC409.11 GEO profiles
PInt SPBC409.11 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC409.11 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC409.11 Fission yeast phenotypic data & analysis
SPD / RIKEN34/34G12Orfeome Localization Data
UniProtKB/SwissProtQ9UUB3Meiotic expression up-regulated protein 18
ModBaseQ9UUB3Database of comparative protein structure models
STRINGQ9UUB3Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595461sequence orphan
RefSeq mRNANM_001021371972h- sequence orphan (meu18), mRNA
European Nucleotide ArchiveAB054302ENA EMBL mapping
European Nucleotide ArchiveCAB52613.1ENA Protein Mapping
UniParcUPI000012EE95UniProt Archive

Literature for meu18

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014