stn1 (SPBC409.12c)

Gene Standard Namestn1 ChromosomeII
Systematic IDSPBC409.12c Gene Start1163251
Synonyms Gene End1161485
Producttelomere cap complex subunit Stn1 Gene Length1767
Feature Typeprotein coding CDS Start1163082
Name Description CDS End1161896
Characterisation Statuspublished CDS Length1187

Ensembl Gene Location
  1. mis13
  2. SPNCRNA.1416
  3. ade7
  4. SPNCRNA.568
  5. meu18
  6. SPNCRNA.1417
  7. SPBTRNAARG.05
  8. stn1
  9. tam7
  10. SPBC409.13
  11. mrps17
  12. SPNCRNA.1418
  13. SPBC409.15
  14. SPBC409.16c
  15. SPNCRNA.1419
  16. SPBC409.17c
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000005abnormal cell morphologyno_name (unrecorded)unrecordedPMID:17715303
FYPO:0002061inviable vegetative cell populationMicroscopystn1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005515protein bindingIPIten1PMID:17715303
GO:0043047single-stranded telomeric DNA bindingIMPPMID:17715303
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0016233telomere cappingIMPPMID:17715303
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0000781chromosome, telomeric regionIDAPMID:17735303
GO:0005634nucleusIDAPMID:16823372
GO:0070188Stn1-Ten1 complexIDAPMID:17715303
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
111632511162974
211629181162820
311626651161485

References

Region Start End Reference
three_prime_UTR11618951161485PMID:21511999
five_prime_UTR11632511163083PMID:21511999
three_prime_UTR11618951161485PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF12659 IPR024263 Pfam Telomere capping C-terminal wHTH 218 322 1
PF10451 IPR018856 Pfam Telomere length regulation Stn1, N-terminal 2 216 1
G3DSA:2.40.50.140 IPR012340 Gene3D 43 131 47
SSF50249 IPR016027 SuperFamily 41 131 57

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0001718OB foldTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001718

Protein Properties

Ave. residue weight 116.91 Da
Charge 22.00
Isoelectric point 10.08
Molecular weight 37.99 kDa
Number of residues 325
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide0.48PMID:23101633
expression microarray evidencecellular response to oxidative stressincreasedPMID:12529438
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.29PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
snt2Lid2 complex subunit Snt2 Negative GeneticPMID:22681890
atg17autophagy associated protein kinase activator Atg17 Negative GeneticPMID:22681890
SPAC824.04WD repeat protein (predicted) Negative GeneticPMID:22681890
SPAC1610.01conserved eukaryotic protein Negative GeneticPMID:22681890
trs130TRAPP complex subunit Trs130 (predicted) Negative GeneticPMID:22681890
atp10F1-F0 ATPase assembly protein (predicted) Negative GeneticPMID:22681890
rex3exonuclease Rex3 (predicted) Negative GeneticPMID:22681890
pab2poly(A) binding protein Pab2 Negative GeneticPMID:22681890
pof9F-box protein Pof9 Negative GeneticPMID:22681890
red1RNA elimination defective protein Red1 Negative GeneticPMID:22681890
SPCC550.03cSki complex RNA helicase Ski2 (predicted) Negative GeneticPMID:22681890
mdm31mitochondrial inner membrane protein Mdm31 (predicted) Negative GeneticPMID:22681890
clr5Clr5 protein Negative GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
ppr2mitochondrial PPR repeat protein Ppr2 Negative GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPBC409.12c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC409.12c Retrieval of eukaryotic orthologs
BioGrid SPBC409.12c BioGRID Interaction Datasets
Bähler Lab SPBC409.12c Cell Cycle Expression Profile
Bähler Lab SPBC409.12c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC409.12c Pheromone response/mating expression profiles
Bähler Lab SPBC409.12c Environmental stress expression profiles
Bähler Lab SPBC409.12c Bähler Lab Transcriptome Viewer
Cyclebase SPBC409.12c Cell Cycle Data
PInt SPBC409.12c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC409.12c Entrez Gene
EntrezGene2541052telomere cap complex subunit Stn1
Uniprot_genenameSTN1
WikiGene2541052telomere cap complex subunit Stn1
SPD / RIKEN08/08A05Orfeome Localization Data
UniProtKB/SwissProtQ0E7J7Protein stn1
ModBaseQ0E7J7Database of comparative protein structure models
Pfam Protein DomainsQ0E7J7Pfam Domain Arrangement
RefSeq_mRNA_predictedXM_001713074972h- telomere cap complex subunit Stn1 (stn1), mRNA
RefSeq_peptide_predictedXP_001713126telomere cap complex subunit Stn1
European Nucleotide ArchiveCAL44730ENA Protein Mapping
UniParcUPI0000DF0454UniProt Archive

Literature for stn1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013