nup107 (SPBC428.01c)


Gene Standard Namenup107 Characterisation Statuspublished
Systematic IDSPBC428.01c Feature Typeprotein coding
SynonymsSPBC582.11c Name Description
Productnucleoporin Nup107 Product Size813aa, 93.26 kDa
Genomic Location Chromosome II, 442078-438999 (3080nt); CDS:442032-439274 (2759nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005515protein bindingIPInup132PMID:15226438861
IPInup131PMID:15226438
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0016973poly(A)+ mRNA export from nucleusIMPPMID:1522643817
GO:0006407rRNA export from nucleusISOSGD:S000002274GO_REF:00000249
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722316
GO:0031965nuclear membraneIDAPMID:1511643251
GO:0005643nuclear poreIDAPMID:1522643854
during meiotic cell cycleIDAPMID:20970342
during mitotic cell cycleIDAPMID:20970342
GO:0031080nuclear pore outer ringIDAPMID:152264387
GO:0005634nucleusIDAPMID:168233722740
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopynup107ΔNullPMID:204732891331
Microscopynup107ΔNullPMID:15116432
Microscopynup107ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000310inviable after spore germination, without cell division, with normal germ tube morphologyMicroscopynup107ΔNullPECO:0000005, PECO:0000137PMID:23697806303
FYPO:0001490inviable elongated vegetative cell385
penetrance FYPO_EXT:0000003Microscopynup107ΔNullPECO:0000005, PECO:0000137PMID:23697806
FYPO:0002273inviable vegetative cell with abnormal cell morphologyMicroscopynup107ΔNullPECO:0000005, PECO:0000137PMID:23697806737
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1442078441916
2441840441793
3441751441718
4441667441541
5441484441392
6441337441229
7441187438999

UTRs

Region Coordinates Reference
five_prime_UTR442078..442033PMID:21511999
three_prime_UTR439273..438999PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04121 Pfam IPR007252 Nuclear pore protein 84/107 120 800 1
PTHR13003 HMMPANTHER IPR007252 Nuclear pore protein 84/107 1 805 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.72 Da
Charge -34.50
Isoelectric point 4.60
Molecular weight 93.26 kDa
Number of residues 813
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
2354.86during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
827during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
1700.23during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
3.9during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
0.89during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999433
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in eukaryotes only2487
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
nup132nucleoporin Nup132 Affinity Capture-WesternPMID:15226438
nup131nucleoporin Nup131 Affinity Capture-WesternPMID:15226438
External References
Database Identifier Description
NBRP SPBC428.01c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC428.01c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC428.01c BioGRID Interaction Datasets
Expression Viewer SPBC428.01c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC428.01c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC428.01c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC428.01c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC428.01c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC428.01c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC428.01c Cell Cycle Data
GEO SPBC428.01c GEO profiles
PInt SPBC428.01c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC428.01c Peptides identified in tandem mass spectrometry proteomics experiments
EntrezGene3361255nucleoporin Nup107
WikiGene3361255nucleoporin Nup107
SPD / RIKEN38/38H03Orfeome Localization Data
UniProtKB/SwissProtQ10331Nucleoporin nup107
ModBaseQ10331Database of comparative protein structure models
STRINGQ10331Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_001018780nucleoporin Nup107
RefSeq mRNANM_001021087972h- nucleoporin Nup107 (nup107), mRNA
European Nucleotide ArchiveCAE54931ENA Protein Mapping
European Nucleotide ArchiveCAE54931.2ENA Protein Mapping
UniParcUPI000228F4D1UniProt Archive

Literature for nup107

Search: Europe PMC or PubMed

Release Version: PomBase:22_45 - 08 Aug 2014