nup107 (SPBC428.01c)

Gene Standard Namenup107 Characterisation Statuspublished
Systematic IDSPBC428.01c Feature Typeprotein coding
SynonymsSPBC582.11c Name Description
Productnucleoporin Nup107 Product Size813aa, 93.26 kDa
Genomic Location Chromosome II, 442078-438999 (3080nt); CDS:442032-439274 (2759nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
protein binding900
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
poly(A)+ mRNA export from nucleus16
Annotation ExtensionEvidenceWith/FromReference
rRNA export from nucleus8
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
nuclear periphery45
Annotation ExtensionEvidenceWith/FromReference
nuclear pore51
nuclear pore outer ring7
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationnup107Δ1468
viable spore populationnup107Δ46

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination, multiple cell divisions, normal septum morphologynup107Δ4
inviable after spore germination, without cell division, with normal germ tube morphologynup107Δ303
inviable elongated vegetative cellnup107Δ440
inviable vegetative cell with abnormal cell morphologynup107Δ390
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons442078..441916, 441840..441793, 441751..441718, 441667..441541, 441484..441392, 441337..441229, 441187..438999
Intron441915..441841, 441792..441752, 441717..441668, 441540..441485, 441391..441338, 441228..441188
5' UTR442078..442033PMID:21511999
CDS442032..441916, 441840..441793, 441751..441718, 441667..441541, 441484..441392, 441337..441229, 441187..439274
3' UTR439273..438999PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04121 Pfam IPR007252 Nuclear pore protein 84/107 122 798 1
PTHR13003 HMMPANTHER IPR007252 Nuclear pore protein 84/107 19 804 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.72 Da
Charge -34.50
Codon Adaptation Index 0.43
Isoelectric point 4.60
Molecular weight 93.26 kDa
Number of residues 813

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS263 2293
Annotation ExtensionEvidenceResidueReference
IDA S263 PMID:25720772
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for nup107 (SPBC428.01c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
827during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
2354.86during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
1700.23during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3.9during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
0.89during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
gene structure updated PMID:21511999435
Taxonomic Conservation
predominantly single copy (one to one)3087
conserved in fungi4608
conserved in eukaryotes4516
conserved in metazoa3498
conserved in vertebrates3473
conserved in eukaryotes only2525

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Load genes that interact physically with SPBC428.01c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity capturesnup131nucleoporin Nup131 Affinity Capture-WesternPMID:15226438
affinity capturesnup132nucleoporin Nup132 Affinity Capture-WesternPMID:15226438
External References
Database Identifier Description
NBRP SPBC428.01c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC428.01c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC428.01c BioGRID Interaction Datasets
Expression Viewer SPBC428.01c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC428.01c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC428.01c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC428.01c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC428.01c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC428.01c Transcriptome Viewer (Bähler Lab)
GEO SPBC428.01c GEO profiles
PInt SPBC428.01c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC428.01c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC428.01c Fission yeast phenotypic data & analysis
Cyclebase SPBC428.01c.1 Cell Cycle Data
SPD / RIKEN38/38H03Orfeome Localization Data
UniProtKB/SwissProtQ10331Nucleoporin nup107
ModBaseQ10331Database of comparative protein structure models
STRINGQ10331Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_001018780nucleoporin Nup107
RefSeq mRNANM_001021087972h- nucleoporin Nup107 (nup107), mRNA
European Nucleotide ArchiveCAE54931.2ENA Protein Mapping
UniParcUPI000228F4D1UniProt Archive

Literature for nup107

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017