nup107 (SPBC428.01c)


Gene Standard Namenup107 Characterisation Statuspublished
Systematic IDSPBC428.01c Feature Typeprotein coding
SynonymsSPBC582.11c Name Description
Productnucleoporin Nup107 Product Size813aa, 93.26 kDa
Genomic Location Chromosome II, 442078-438999 (3080nt); CDS:442032-439274 (2759nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
protein binding848
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
poly(A)+ mRNA export from nucleus17
Annotation ExtensionEvidenceWith/FromReference
rRNA export from nucleus9
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2316
Annotation ExtensionEvidenceWith/FromReference
nuclear periphery41
Annotation ExtensionEvidenceWith/FromReference
nuclear pore53
Annotation ExtensionEvidenceWith/FromReference
nuclear pore outer ring7
Annotation ExtensionEvidenceWith/FromReference
nucleus2690
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationnup107ΔNull1427
viable spore populationnup107ΔNull27

Cell Phenotype

Term NameAlleleExpressionCount
inviable after spore germination, multiple cell divisions, normal septum morphologynup107ΔNull4
inviable after spore germination, without cell division, with normal germ tube morphologynup107ΔNull303
inviable elongated vegetative cell405
penetrance FYPO_EXT:0000003nup107ΔNull
inviable vegetative cell with abnormal cell morphologynup107ΔNull746
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1442078441916
2441840441793
3441751441718
4441667441541
5441484441392
6441337441229
7441187438999

UTRs

Region Coordinates Reference
five_prime_UTR442078..442033PMID:21511999
three_prime_UTR439273..438999PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04121 Pfam IPR007252 Nuclear pore protein 84/107 120 800 1
PTHR13003 HMMPANTHER IPR007252 Nuclear pore protein 84/107 1 805 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.72 Da
Charge -34.50
Isoelectric point 4.60
Molecular weight 93.26 kDa
Number of residues 813
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
827during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
2354.86during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
1700.23during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3.9during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.89during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999432
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3432
conserved in vertebrates3407
conserved in eukaryotes only2503
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
nup132nucleoporin Nup132 Affinity Capture-WesternPMID:15226438
nup131nucleoporin Nup131 Affinity Capture-WesternPMID:15226438
External References
Database Identifier Description
NBRP SPBC428.01c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC428.01c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC428.01c BioGRID Interaction Datasets
Expression Viewer SPBC428.01c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC428.01c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC428.01c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC428.01c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC428.01c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC428.01c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC428.01c Cell Cycle Data
GEO SPBC428.01c GEO profiles
PInt SPBC428.01c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC428.01c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC428.01c Fission yeast phenotypic data & analysis
SPD / RIKEN38/38H03Orfeome Localization Data
UniProtKB/SwissProtQ10331Nucleoporin nup107
ModBaseQ10331Database of comparative protein structure models
STRINGQ10331Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_001018780nucleoporin Nup107
RefSeq mRNANM_001021087972h- nucleoporin Nup107 (nup107), mRNA
European Nucleotide ArchiveCAE54931.2ENA Protein Mapping
UniParcUPI000228F4D1UniProt Archive

Literature for nup107

Search: Europe PMC or PubMed

Release Version: PomBase:25_48 - 10 Jan 2015