pre3 (SPBC4C3.10c)

Gene Standard Namepre3 ChromosomeII
Systematic IDSPBC4C3.10c Gene Start3117052
Synonyms Gene End3118883
Product20S proteasome complex subunit beta 1 Pre3 (predicted) Gene Length1832
Feature Typeprotein coding CDS Start3117669
Name Description CDS End3118627
Characterisation Statusbiological_role_inferred CDS Length959

Ensembl Gene Location
  1. SPBC1778.07
  2. arc3
  3. SPBC1778.09
  4. ppk21
  5. pre3
  6. SPBC4C3.09
  7. SPNCRNA.1580
  8. mug136
  9. prl23
  10. SPBC4C3.07
  11. syp1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002061inviable vegetative cell populationMicroscopypre3delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0004175endopeptidase activity
contributes_toISOSGD:S000003538GO_REF:0000024
GO:0004298threonine-type endopeptidase activityIEAUniProtKB:KW-0888GO_REF:0000037
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0007346regulation of mitotic cell cycleICGO:0000502GO_REF:0000001
GO:0043161proteasomal ubiquitin-dependent protein catabolic processNASGO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
GO:0019774proteasome core complex, beta-subunit complexISOSGD:S000003538GO_REF:0000024
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
131170523117724
231177683117850
331179033118035
431182193118883

References

Region Start End Reference
three_prime_UTR31186283118883PMID:21511999
three_prime_UTR31186283118883PMID:21511999
five_prime_UTR31170523117668PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00227 IPR001353 Pfam Proteasome, subunit alpha/beta 22 202 14
PS51476 IPR023333 Prosite Profiles Proteasome B-type subunit 24 203 7
PS00854 IPR016050 Prosite Patterns Proteasome, beta-type subunit, conserved site 28 75 8
G3DSA:3.60.20.10 Gene3D 25 211 19
SSF56235 SuperFamily 19 210 22
PR00141 IPR000243 PRINTS Peptidase T1A, proteasome beta-subunit 32 47 2
PR00141 IPR000243 PRINTS Peptidase T1A, proteasome beta-subunit 189 200 2
PR00141 IPR000243 PRINTS Peptidase T1A, proteasome beta-subunit 153 164 2
PR00141 IPR000243 PRINTS Peptidase T1A, proteasome beta-subunit 164 175 2
PTHR11599 hmmpanther 20 213 14
PTHR11599:SF4 hmmpanther 20 213 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 108.69 Da
Charge 0.00
Isoelectric point 6.51
Molecular weight 24.56 kDa
Number of residues 226
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide47839.27PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide20985.54PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.6PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide6.3PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in bacteria
conserved in metazoa
conserved in vertebrates
conserved in archaea
Manually curated orthologous groups
SpeciesGeneDescription

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Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
uch2ubiquitin C-terminal hydrolase Uch2 Affinity Capture-MSPMID:20838651
ubp6ubiquitin C-terminal hydrolase Ubp6 Affinity Capture-MSPMID:20838651
rpn1119S proteasome regulatory subunit Rpn11 Affinity Capture-MSPMID:20838651
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External References
Database Identifier Description
NBRP SPBC4C3.10c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC4C3.10c Retrieval of eukaryotic orthologs
BioGrid SPBC4C3.10c BioGRID Interaction Datasets
Bähler Lab SPBC4C3.10c Cell Cycle Expression Profile
Bähler Lab SPBC4C3.10c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC4C3.10c Pheromone response/mating expression profiles
Bähler Lab SPBC4C3.10c Environmental stress expression profiles
Bähler Lab SPBC4C3.10c Bähler Lab Transcriptome Viewer
Cyclebase SPBC4C3.10c Cell Cycle Data
PInt SPBC4C3.10c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC4C3.10c Entrez Gene
IntEnz3.4.25.1
EntrezGene254087820S proteasome component beta 1 Pre3 (predicted)
WikiGene254087820S proteasome component beta 1 Pre3 (predicted)
UniProtKB/SwissProtO43063Probable proteasome subunit beta type-6
ModBaseO43063Database of comparative protein structure models
Pfam Protein DomainsO43063Pfam Domain Arrangement
RefSeq PeptideNP_59629520S proteasome component beta 1 Pre3 (predicted)
RefSeq mRNANM_001022216972h- 20S proteasome component beta 1 Pre3 (predicted) (pre3), mRNA
MEROPST01.010
European Nucleotide ArchiveCAA16832ENA Protein Mapping
SPD / RIKEN13/13E12Orfeome Localization Data
UniParcUPI00001325C5UniProt Archive

Literature for pre3
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013