str1 (SPBC4F6.09)


Gene Standard Namestr1 Characterisation Statuspublished
Systematic IDSPBC4F6.09 Feature Typeprotein coding
SynonymsSPNCRNA.106 Name Description
Productsiderophore-iron transporter Str1 Product Size612aa, 68.16 kDa
Genomic Location Chromosome II, 2704645-2707648 (3004nt); CDS:2705523-2707361 (1839nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0015343siderophore transmembrane transporter activityIMPPMID:128884923
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0034755iron ion transmembrane transportIMPPMID:1288849212
GO:0044718siderophore transmembrane transportIMPPMID:128884923
GO:0015891siderophore transportIMPPMID:128884924
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005783endoplasmic reticulumIDAPMID:16823372594
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371016
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopystr1ΔNullPECO:0000005, PECO:0000137PMID:236978063755
Microscopystr1ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopystr1ΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Target Of
RelationshipGeneProductReference
regulated by fep1 iron-sensing transcription factor Fep1 PMID:12888492
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
127046452707648

UTRs

Region Start End Reference
three_prime_UTR27073622707648PMID:21511999
five_prime_UTR27046452705522PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06609 Pfam IPR010573 Fungal trichothecene efflux pump 128 547 1
TMhelix TMHMM 299 321 959
TMhelix TMHMM 498 520 959
TMhelix TMHMM 573 592 959
TMhelix TMHMM 184 206 959
TMhelix TMHMM 405 427 959
TMhelix TMHMM 218 235 959
TMhelix TMHMM 331 353 959
TMhelix TMHMM 161 180 959
TMhelix TMHMM 119 141 959
TMhelix TMHMM 434 453 959
TMhelix TMHMM 91 109 959
TMhelix TMHMM 463 485 959
TMhelix TMHMM 250 272 959
TMhelix TMHMM 366 385 959
PS50850 Prosite Profiles IPR020846 Major facilitator superfamily domain 92 596 55
PTHR24003 HMMPANTHER 25 612 17
PTHR24003:SF84 HMMPANTHER 25 612 1
G3DSA:1.20.1250.20 Gene3D 93 249 69
G3DSA:1.20.1250.20 Gene3D 364 523 69
G3DSA:1.20.1250.20 Gene3D 333 348 69
SSF103473 SuperFamily IPR016196 321 522 76
SSF103473 SuperFamily IPR016196 93 316 76
Coil ncoils Rabaptin coiled-coil domain 10 31 975
Low complexity (SEG) seg 507 519
Low complexity (SEG) seg 468 477
Low complexity (SEG) seg 307 320
Low complexity (SEG) seg 159 175
Low complexity (SEG) seg 134 145
Low complexity (SEG) seg 98 111

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 111.37 Da
Charge 4.50
Isoelectric point 7.94
Molecular weight 68.16 kDa
Number of residues 612
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00696phosphorylated residuePMID:195477441192
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
3398.74during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
7during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.39during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
merged with ncRNA SPNCRNA.1061
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4564
conserved in eukaryotes4482
conserved in bacteria1001
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
eso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
External References
Database Identifier Description
NBRP SPBC4F6.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC4F6.09 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC4F6.09 BioGRID Interaction Datasets
Expression Viewer SPBC4F6.09 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC4F6.09 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC4F6.09 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC4F6.09 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC4F6.09 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC4F6.09 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC4F6.09 Cell Cycle Data
GEO SPBC4F6.09 GEO profiles
PInt SPBC4F6.09 Protein-Protein Interaction Predictor (Bähler Lab)
EntrezGene2540217siderophore-iron transporter Str1
WikiGene2540217siderophore-iron transporter Str1
SPD / RIKEN36/36G10Orfeome Localization Data
UniProtKB/SwissProtO74395Siderophore iron transporter 1
ModBaseO74395Database of comparative protein structure models
StringO74395Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596109siderophore-iron transporter Str1
RefSeq mRNANM_001022026972h- siderophore-iron transporter Str1 (str1), mRNA
European Nucleotide ArchiveAU008311ENA EMBL mapping
European Nucleotide ArchiveCAA20729ENA Protein Mapping
UniParcUPI0000069A5DUniProt Archive

Literature for str1

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014