str1 (SPBC4F6.09)

Gene Standard Namestr1 Characterisation Statuspublished
Systematic IDSPBC4F6.09 Feature Typeprotein coding
SynonymsSPNCRNA.106 Name Description
Productsiderophore-iron transporter Str1 Product Size612aa, 68.16 kDa
Genomic Location Chromosome II, 2704645-2707648 (3004nt); CDS:2705523-2707361 (1839nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
siderophore transmembrane transporter activity3
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
iron assimilation by chelation and transport5
Annotation ExtensionEvidenceWith/FromReference
iron ion transmembrane transport12
Annotation ExtensionEvidenceWith/FromReference
siderophore transmembrane transport3
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
endoplasmic reticulum594
Annotation ExtensionEvidenceWith/FromReference
integral component of membrane1018
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopystr1ΔNullPMID:204732893759
Microscopystr1ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3089
penetrance FYPO_EXT:0000001Microscopystr1ΔNullPECO:0000005, PECO:0000137PMID:23697806
Target Of
GO regulated by fep1 iron-sensing transcription factor Fep1 PMID:12888492
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06609 Pfam IPR010573 Fungal trichothecene efflux pump 128 547 1
TMhelix TMHMM 299 321 959
TMhelix TMHMM 573 592 959
TMhelix TMHMM 498 520 959
TMhelix TMHMM 184 206 959
TMhelix TMHMM 405 427 959
TMhelix TMHMM 218 235 959
TMhelix TMHMM 331 353 959
TMhelix TMHMM 161 180 959
TMhelix TMHMM 119 141 959
TMhelix TMHMM 434 453 959
TMhelix TMHMM 91 109 959
TMhelix TMHMM 463 485 959
TMhelix TMHMM 250 272 959
TMhelix TMHMM 366 385 959
PS50850 Prosite Profiles IPR020846 Major facilitator superfamily domain 92 596 55
PTHR24003 HMMPANTHER 25 612 17
PTHR24003:SF84 HMMPANTHER 25 612 1
1.20.1250.20 Gene3D 364 523 72
1.20.1250.20 Gene3D 333 348 72
1.20.1250.20 Gene3D 93 249 72
SSF103473 SuperFamily IPR016196 Major facilitator superfamily domain, general substrate transporter 321 522 76
SSF103473 SuperFamily IPR016196 Major facilitator superfamily domain, general substrate transporter 93 316 76
Coil ncoils Rabaptin coiled-coil domain 10 31 968

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount

Protein Properties

Ave. residue weight 111.37 Da
Charge 4.50
Isoelectric point 7.94
Molecular weight 68.16 kDa
Number of residues 612

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineexperimental evidenceS610PMID:247631071670
experimental evidenceS607PMID:24763107
present during mitotic M phaseexperimental evidenceS41PMID:21712547
present during mitotic M phaseexperimental evidenceS36PMID:21712547
present during mitotic M phaseexperimental evidenceS62PMID:21712547
present during mitotic M phaseexperimental evidenceS607PMID:21712547
experimental evidenceS62PMID:24763107
experimental evidenceS48PMID:24763107
present during mitotic M phaseexperimental evidenceS48PMID:21712547
present during mitotic M phaseexperimental evidenceS64PMID:21712547
MOD:00047O-phospho-L-threonineexperimental evidenceT35PMID:21712547692
present during mitotic M phase
MOD:00696phosphorylated residueNASPMID:195477441922
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
5060during GO:0000080PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
4692during GO:0000085PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
3398.74during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
4534during GO:0072690PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
7during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
0.39during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
merged with ncRNA SPNCRNA.1061
Species Distribution
conserved in fungi4600
conserved in eukaryotes4514
conserved in bacteria1000

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
eso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
External References
Database Identifier Description
NBRP SPBC4F6.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC4F6.09 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC4F6.09 BioGRID Interaction Datasets
Expression Viewer SPBC4F6.09 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC4F6.09 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC4F6.09 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC4F6.09 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC4F6.09 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC4F6.09 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC4F6.09 Cell Cycle Data
GEO SPBC4F6.09 GEO profiles
PInt SPBC4F6.09 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC4F6.09 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC4F6.09 Fission yeast phenotypic data & analysis
SPD / RIKEN36/36G10Orfeome Localization Data
UniProtKB/SwissProtO74395Siderophore iron transporter 1
ModBaseO74395Database of comparative protein structure models
STRINGO74395Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596109siderophore-iron transporter Str1
RefSeq mRNANM_001022026972h- siderophore-iron transporter Str1 (str1), mRNA
European Nucleotide ArchiveCAA20729.1ENA Protein Mapping
UniParcUPI0000069A5DUniProt Archive

Literature for str1

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014