pex11 (SPBC582.09)


Gene Standard Namepex11 Characterisation Statusbiological_role_inferred
Systematic IDSPBC582.09 Feature Typeprotein coding
Synonyms Name Description
Productperoxisomal biogenesis factor 11 (predicted) Product Size238aa, 26.48 kDa
Genomic Location Chromosome II, 434811-436173 (1363nt); CDS:434873-435973 (1101nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0016559peroxisome fissionIEAIPR008733GO_REF:00000021
GO:0007031peroxisome organizationISOSGD:S000005507GO_REF:000002422
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005779integral component of peroxisomal membraneIEAIPR008733GO_REF:00000025
GO:0005739mitochondrionIDAPMID:16823372758
GO:0005778peroxisomal membraneISOSGD:S000005507GO_REF:000002414
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopypex11ΔNullPMID:204732893759
Microscopypex11ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3089
penetrance FYPO_EXT:0000001Microscopypex11ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1434811434917
2434962434991
3435283435761
4435811436173

UTRs

Region Coordinates Reference
three_prime_UTR435974..436173PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF05648 Pfam IPR008733 Peroxisomal biogenesis factor 11 12 234 1
PTHR12652:SF9 HMMPANTHER 1 234 1
PTHR12652 HMMPANTHER IPR008733 Peroxisomal biogenesis factor 11 1 234 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 111.26 Da
Charge 10.50
Isoelectric point 9.63
Molecular weight 26.48 kDa
Number of residues 238
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
33262during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
37638during GO:0000084PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
34510during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
32017during GO:0000087PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
17725.63during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
36083during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
16300.23during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
5.2during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
1.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in eukaryotes only2497
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
dad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
srb11cyclin CycC, Srb mediator subunit Srb11 Positive GeneticPMID:22681890
rem1meiosis-specific cyclin Rem1 Positive GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
hip1hira protein, histone chaperone Hip1 Positive GeneticPMID:22681890
mcl1DNA polymerase alpha accessory factor Mcl1 Positive GeneticPMID:22681890
SPBC1105.08EMP70 family Positive GeneticPMID:22681890
slx4structure-specific endonuclease subunit Slx4 Positive GeneticPMID:22681890
fft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Negative GeneticPMID:22681890
iwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:22681890
lsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Positive GeneticPMID:22681890
SPAC1952.06cspliceosomal complex subunit (predicted) Positive GeneticPMID:22681890
usp102U1 snRNP-associated protein Usp102 Positive GeneticPMID:22681890
rhn1RNA polymerase II transcription termination factor homolog Positive GeneticPMID:22681890
rok1ATP-dependent RNA helicase Rok1 (predicted) Positive GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPBC582.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC582.09 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC582.09 BioGRID Interaction Datasets
Expression Viewer SPBC582.09 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC582.09 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC582.09 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC582.09 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC582.09 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC582.09 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC582.09 Cell Cycle Data
GEO SPBC582.09 GEO profiles
PInt SPBC582.09 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC582.09 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC582.09 Fission yeast phenotypic data & analysis
SPD / RIKEN17/17C06Orfeome Localization Data
UniProtKB/SwissProtQ10333Peroxisomal biogenesis factor 11
ModBaseQ10333Database of comparative protein structure models
STRINGQ10333Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595177peroxisomal biogenesis factor 11 (predicted)
RefSeq mRNANM_001021085972h- peroxisomal biogenesis factor 11 (predicted) (pex11), mRNA
European Nucleotide ArchiveCAB46672.1ENA Protein Mapping
UniParcUPI000013A3B5UniProt Archive

Literature for pex11

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014