pex11 (SPBC582.09)


Gene Standard Namepex11 Characterisation Statusbiological_role_inferred
Systematic IDSPBC582.09 Feature Typeprotein coding
Synonyms Name Description
Productperoxisomal biogenesis factor 11 (predicted) Product Size238aa, 26.48 kDa
Genomic Location Chromosome II, 434811-436173 (1363nt); CDS:434873-435973 (1101nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
peroxisome fission1
Annotation ExtensionEvidenceWith/FromReference
peroxisome organization22
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
integral component of peroxisomal membrane5
Annotation ExtensionEvidenceWith/FromReference
mitochondrion761
Annotation ExtensionEvidenceWith/FromReference
peroxisomal membrane13
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationpex11ΔNull3795

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologypex11ΔNull3093
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons434811..434917, 434962..434991, 435283..435761, 435811..436173
Introns434918..434961, 434992..435282, 435762..435810
mRNA434811..436173
5' UTR434811..434872AU009201
CDS434873..434917, 434962..434991, 435283..435761, 435811..435973
3' UTR435974..436173PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF05648 Pfam IPR008733 Peroxisomal biogenesis factor 11 12 234 1
PTHR12652 HMMPANTHER 1 234 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 111.26 Da
Charge 10.50
Isoelectric point 9.63
Molecular weight 26.48 kDa
Number of residues 238
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
33262during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
37638during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
34510during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
32017during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
36083during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
17725.63during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
16300.23during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
5.2during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
1.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byepe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withdad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
negative genetic interaction withfft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Negative GeneticPMID:22681890
positive genetic interaction withhip1hira protein, histone chaperone Hip1 Positive GeneticPMID:22681890
positive genetic interaction withiwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withkin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
positive genetic interaction withlsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Positive GeneticPMID:22681890
positive genetic interaction withmcl1DNA polymerase alpha accessory factor Mcl1 Positive GeneticPMID:22681890
positive genetic interaction withrem1meiosis-specific cyclin Rem1 Positive GeneticPMID:22681890
positive genetic interaction withrhn1RNA polymerase II transcription termination factor homolog Positive GeneticPMID:22681890
positive genetic interaction withrok1ATP-dependent RNA helicase Rok1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withslx4structure-specific endonuclease subunit Slx4 Positive GeneticPMID:22681890
positive genetic interaction withSPAC1952.06cspliceosomal complex subunit (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC1105.08EMP70 family Positive GeneticPMID:22681890
positive genetic interaction withsrb11cyclin CycC, Srb mediator subunit Srb11 Positive GeneticPMID:22681890
positive genetic interaction withusp102U1 snRNP-associated protein Usp102 Positive GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPBC582.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC582.09 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC582.09 BioGRID Interaction Datasets
Expression Viewer SPBC582.09 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC582.09 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC582.09 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC582.09 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC582.09 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC582.09 Transcriptome Viewer (Bähler Lab)
GEO SPBC582.09 GEO profiles
PInt SPBC582.09 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC582.09 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC582.09 Fission yeast phenotypic data & analysis
Cyclebase SPBC582.09.1 Cell Cycle Data
SPD / RIKEN17/17C06Orfeome Localization Data
UniProtKB/SwissProtQ10333Peroxisomal biogenesis factor 11
ModBaseQ10333Database of comparative protein structure models
STRINGQ10333Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_595177peroxisomal biogenesis factor 11 (predicted)
RefSeq mRNANM_001021085972h- peroxisomal biogenesis factor 11 (predicted) (pex11), mRNA
European Nucleotide ArchiveCAB46672.1ENA Protein Mapping
UniParcUPI000013A3B5UniProt Archive

Literature for pex11

Search: Europe PMC or PubMed

Release Version: PomBase:26_51 - 07 Apr 2015