SPBC582.10c

Gene Standard NameUnassigned ChromosomeII
Systematic IDSPBC582.10c Gene Start439017
Synonyms Gene End436090
ProductATP-dependent DNA helicase Rhp16b (predicted) Gene Length2928
Feature Typeprotein coding CDS Start438777
Name Description CDS End436233
Characterisation Statusbiological_role_inferred CDS Length2545

Ensembl Gene Location
  1. SPNCRNA.1356
  2. mcp6
  3. rpn7
  4. SPBC582.08
  5. pex11
  6. SPBC582.10c
  7. SPNCRNA.1357
  8. nup107
  9. eca39
  10. SPNCRNA.1358
  11. SPNCRNA.1359
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPBC582.10cdelta (deletion)deletionPMID:20473289
SPBC582.10cdelta (deletion)deletionPMID:12618370
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0003677DNA bindingIEAUniProtKB:KW-0238GO_REF:0000037
GO:0004386helicase activityIEAUniProtKB:KW-0347GO_REF:0000037
GO:0005524ATP bindingIEAUniProtKB:KW-0067GO_REF:0000037
GO:0008094DNA-dependent ATPase activityISOSGD:S000000318GO_REF:0000024
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006289nucleotide-excision repairISOSGD:S000000318GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0000113nucleotide-excision repair factor 4 complexISOSGD:S000000318GO_REF:0000024
GO:0005737cytoplasmIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1439017437989
2437936436090

References

Region Start End Reference
five_prime_UTR439017438778PMID:21511999
three_prime_UTR436232436090PMID:21511999
three_prime_UTR436232436090PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00271 IPR001650 Pfam Helicase, C-terminal 689 767 69
PF00176 IPR000330 Pfam SNF2-related 236 554 20
SM00490 IPR001650 SMART Helicase, C-terminal 684 767 67
SM00487 IPR014001 SMART Helicase, superfamily 1/2, ATP-binding domain 229 445 69
PS51192 IPR014001 Prosite Profiles Helicase, superfamily 1/2, ATP-binding domain 249 433 69
PS51194 IPR001650 Prosite Profiles Helicase, C-terminal 662 816 69
G3DSA:3.40.50.300 Gene3D 230 432 279
G3DSA:3.40.50.300 Gene3D 646 799 279
SSF52540 SuperFamily 210 472 294
SSF52540 SuperFamily 639 827 294
SSF52540 SuperFamily 491 573 294
Coil ncoils Rabaptin coiled-coil domain 780 801 974
PTHR10799:SF232 hmmpanther 43 827 1
PTHR10799 hmmpanther 43 827 21

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:18257517

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000174DEAD/DEAH box helicaseTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000174
PBO:0000175helicase C-terminal domainTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000175

Protein Properties

Ave. residue weight 113.19 Da
Charge 40.00
Isoelectric point 9.91
Molecular weight 93.95 kDa
Number of residues 830
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.23PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide0.73PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
dsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:21504829
ste20Rictor homolog, Ste20 Positive GeneticPMID:22681890
cia1histone chaperone Cia1 Positive GeneticPMID:18818364
cid12poly(A) polymerase Cid12 Positive GeneticPMID:18818364
cgs2cAMP-specific phosphodiesterase Cgs2 Positive GeneticPMID:22681890
meu10GPI anchored cell surface protein involved in ascospore wall assembly Meu10 Positive GeneticPMID:22681890
alg12dolichyl pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase Alg12 (predicted) Negative GeneticPMID:22681890
SPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:18818364
SPBC31F10.02acyl-CoA hydrolase (predicted) Positive GeneticPMID:22681890
spp27RNA polymerase I upstream activation factor complex subunit Spp27 Negative GeneticPMID:22681890
gar2nucleolar protein required for rRNA processing Positive GeneticPMID:22681890
dep1Sds3-like family protein Dep1 Positive GeneticPMID:22681890
hmt2sulfide-quinone oxidoreductase Positive GeneticPMID:22681890
alm1medial ring protein Alm1 Negative GeneticPMID:22681890
SPBC725.10tspO homolog/ peripheral benzodiazepine receptor homolog, involved in the transport cytoplas/mitochondrial of haem (predicted) Positive GeneticPMID:22681890
mal3EB1 family Mal3 Positive GeneticPMID:22681890
SPAP8A3.07cphospho-2-dehydro-3-deoxyheptonate aldolase (predicted) Negative GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPBC582.10c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC582.10c Retrieval of eukaryotic orthologs
BioGrid SPBC582.10c BioGRID Interaction Datasets
Bähler Lab SPBC582.10c Cell Cycle Expression Profile
Bähler Lab SPBC582.10c Meiosis/Sporulation Expression Profies
Bähler Lab SPBC582.10c Pheromone response/mating expression profiles
Bähler Lab SPBC582.10c Environmental stress expression profiles
Bähler Lab SPBC582.10c Bähler Lab Transcriptome Viewer
Cyclebase SPBC582.10c Cell Cycle Data
PInt SPBC582.10c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC582.10c Entrez Gene
WikiGene2540907ATP-dependent DNA helicase Rhp16b (predicted)
EntrezGene2540907ATP-dependent DNA helicase Rhp16b (predicted)
SPD / RIKEN29/29C11Orfeome Localization Data
UniProtKB/SwissProtQ10332Uncharacterized ATP-dependent helicase C582.10c
ModBaseQ10332Database of comparative protein structure models
Pfam Protein DomainsQ10332Pfam Domain Arrangement
RefSeq PeptideNP_595178ATP-dependent DNA helicase Rhp16b (predicted)
RefSeq mRNANM_001021086972h- ATP-dependent DNA helicase Rhp16b (predicted) (SPBC582.10c), mRNA
European Nucleotide ArchiveBAA87269ENA Protein Mapping
European Nucleotide ArchiveCAB46673ENA Protein Mapping
UniParcUPI000013A3B6UniProt Archive

Literature for SPBC582.10c
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013