rps001 (SPBC685.06)


Gene Standard Namerps001 Characterisation Statuspublished
Systematic IDSPBC685.06 Feature Typeprotein coding
Synonyms Name Description
Product40S ribosomal protein S0A (p40) Product Size292aa, 31.76 kDa
Genomic Location Chromosome II, 2778868-2779942 (1075nt); CDS:2778923-2779856 (934nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
protein binding862
Annotation ExtensionEvidenceWith/FromReference
structural constituent of ribosome257
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation469
Annotation ExtensionEvidenceWith/FromReference
ribosomal small subunit assembly5
Annotation ExtensionEvidenceWith/FromReference
ribosomal small subunit biogenesis55
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2306
Annotation ExtensionEvidenceWith/FromReference
cytosolic small ribosomal subunit64
Annotation ExtensionEvidenceWith/FromReference
nucleus2690
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
slow vegetative cell population growthrps001Δ340
viable vegetative cell populationrps001Δ3831

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologyrps001Δ3099
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2778868..2778961, 2779017..2779942
Intron2778962..2779016
5' UTR2778868..2778922PMID:21511999
3' UTR2779857..2779942PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00318 Pfam IPR001865 Ribosomal protein S2 20 115 3
PF00318 Pfam IPR001865 Ribosomal protein S2 116 184 3
PF16122 Pfam IPR032281 40S ribosomal protein SA, C-terminal domain 204 291 2
PS00963 Prosite Patterns IPR018130 Ribosomal protein S2, conserved site 121 145 2
PTHR11489 HMMPANTHER IPR005707 Ribosomal protein S2, eukaryotic/archaeal 5 292 2
PTHR11489:SF9 HMMPANTHER 5 292 1
3.40.50.10490 Gene3D Ribosomal protein S2, conserved site 34 217 5
SSF52313 SuperFamily IPR023591 Ribosomal protein S2, flavodoxin-like domain 14 202 3
Coil ncoils Predicted coiled-coil protein (DUF2205) 212 232 1050
MF_03015 hamap IPR027498 Ribosomal protein S2, eukaryotic 4 271 2
PR00395 PRINTS IPR001865 Ribosomal protein S2 17 35 3
PR00395 PRINTS IPR001865 Ribosomal protein S2 47 56 3
PR00395 PRINTS IPR001865 Ribosomal protein S2 96 113 3
PR00395 PRINTS IPR001865 Ribosomal protein S2 121 138 3
PR00395 PRINTS IPR001865 Ribosomal protein S2 138 149 3
PR00395 PRINTS IPR001865 Ribosomal protein S2 159 173 3
TIGR01012 tigrfam IPR005707 Ribosomal protein S2, eukaryotic/archaeal 14 207 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 108.77 Da
Charge -6.50
Codon Adaptation Index 0.74
Isoelectric point 4.95
Molecular weight 31.76 kDa
Number of residues 292
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1675
present during cellular response to thiabendazoleT106
present during cellular response to thiabendazoleS45
Annotation ExtensionEvidenceResidueReference
present during cellular response to thiabendazole IDA S45 PMID:18257517
present during cellular response to thiabendazole IDA T106 PMID:18257517
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for rps001 (SPBC685.06)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
650318during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
633405during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
642540during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
643587during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
636115during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
77480.18during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
15421.55during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
93during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
7.9during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4604
conserved in eukaryotes4514
conserved in bacteria1000
conserved in metazoa3422
conserved in vertebrates3397
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load gene that interact physically with SPBC685.06 into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity capturesaip1actin cortical patch component Aip1 Affinity Capture-MSPMID:12062100
affinity capturesrad2414-3-3 protein Rad24 Affinity Capture-MSPMID:12062100
affinity captureshsp90Hsp90 chaperone Affinity Capture-MSPMID:12062100
affinity capturesrad2514-3-3 protein Rad25 Affinity Capture-MSPMID:12062100
affinity capturespabpmRNA export shuttling protein Affinity Capture-WesternPMID:12062100
affinity captured bymog1Ran GTPase binding protein Mog1 Affinity Capture-WesternPMID:17651922
Genetic Interactions

Source: BioGRID

Load gene that interact genetically with SPBC685.06 into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
overexpression rescuesrad17RFC related checkpoint protein Rad17 Dosage RescuePMID:12062100
overexpression rescuescdc2cyclin-dependent protein kinase Cdk1/Cdc2 Dosage RescuePMID:12062100
overexpression rescuesrad9checkpoint clamp complex protein Rad9 Dosage RescuePMID:12062100
overexpression rescuesrad26ATRIP, ATR checkpoint kinase regulatory subunit Rad26 Dosage RescuePMID:12062100
overexpression rescuescds1replication checkpoint kinase Cds1 Dosage RescuePMID:12062100
overexpression rescuesrad1checkpoint clamp complex protein Rad1 Dosage RescuePMID:12062100
overexpression rescuesrad3ATR checkpoint kinase Rad3 Dosage RescuePMID:12062100
synthetic growth defect withcds1replication checkpoint kinase Cds1 Synthetic Growth DefectPMID:12062100
synthetic growth defect withrad3ATR checkpoint kinase Rad3 Synthetic Growth DefectPMID:12062100
synthetically rescuesmog1Ran GTPase binding protein Mog1 Synthetic RescuePMID:17651922
synthetically rescued byrad3ATR checkpoint kinase Rad3 Synthetic RescuePMID:12218190
External References
Database Identifier Description
NBRP SPBC685.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC685.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC685.06 BioGRID Interaction Datasets
Expression Viewer SPBC685.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC685.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC685.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC685.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC685.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC685.06 Transcriptome Viewer (Bähler Lab)
GEO SPBC685.06 GEO profiles
PInt SPBC685.06 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC685.06 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC685.06 Fission yeast phenotypic data & analysis
Cyclebase SPBC685.06.1 Cell Cycle Data
SPD / RIKEN13/13A11Orfeome Localization Data
UniProtKB/SwissProtQ9Y7L840S ribosomal protein S0-A
ModBaseQ9Y7L8Database of comparative protein structure models
STRINGQ9Y7L8Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59614040S ribosomal protein S0A
RefSeq mRNANM_001022058972h- 40S ribosomal protein S0A (rps001), mRNA
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveCAB39363ENA Protein Mapping
UniParcUPI0000134B8DUniProt Archive

Literature for rps001

Search: Europe PMC or PubMed

Release Version: PomBase:30_57 - 27 Jan 2016