SPBC725.04

Gene Standard NameUnassigned ChromosomeII
Systematic IDSPBC725.04 Gene Start1208655
Synonyms Gene End1210856
Productoxalyl-CoA decarboxylase (predicted) Gene Length2202
Feature Typeprotein coding CDS Start1208965
Name Description CDS End1210722
Characterisation Statusconserved_unknown CDS Length1758

Ensembl Gene Location
  1. SPBC725.01
  2. SPNCRNA.1420
  3. mpr1
  4. SPBC725.03
  5. SPBC725.04
  6. SPBC725.05c
  7. SPNCRNA.1421
  8. ppk31
  9. pex5
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001491viable vegetative cellMicroscopySPBC725.04delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0000287magnesium ion bindingIEAIPR012000GO_REF:0000002
GO:0016831carboxy-lyase activityIEAUniProtKB:KW-0210GO_REF:0000037
GO:0030976thiamine pyrophosphate bindingIEAIPR011766, IPR012001, IPR012000GO_REF:0000002
GO Cellular Component

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0005737cytoplasmISOSGD:S000000746GO_REF:0000024
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
112086551210626
212106781210856

References

Region Start End Reference
five_prime_UTR12086551208964PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00205 IPR012000 Pfam Thiamine pyrophosphate enzyme, central domain 192 320 6
PF02776 IPR012001 Pfam Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain 5 170 6
PF02775 IPR011766 Pfam Thiamine pyrophosphate enzyme, C-terminal TPP-binding 401 544 6
G3DSA:3.40.50.970 Gene3D 2 180 13
G3DSA:3.40.50.970 Gene3D 359 553 13
G3DSA:3.40.50.1220 Gene3D 183 329 10
SSF52467 SuperFamily 186 333 11
SSF52518 SuperFamily 363 560 12
SSF52518 SuperFamily 2 180 12
PTHR18968 hmmpanther 1 560 6
PTHR18968:SF6 hmmpanther 1 560 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.04 Da
Charge 7.00
Isoelectric point 8.13
Molecular weight 61.94 kDa
Number of residues 568
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide7416.76PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide5615.24PMID:23101633
RNA levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide3.8PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.77PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in bacteria
conserved in metazoa
conserved in vertebrates
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ppm1leucine carboxyl methyltransferase Ppm1 (predicted) Positive GeneticPMID:22681890
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:22681890
gda1guanosine-diphosphatase Gda1 Negative GeneticPMID:22681890
jmj4Jmj4 protein (predicted) Positive GeneticPMID:22681890
pof13F-box protein Pof13 Negative GeneticPMID:22681890
nup60nucleoporin Nup60 Negative GeneticPMID:22681890
SPBC1778.03cNADH pyrophosphatase (predicted) Positive GeneticPMID:22681890
hrp3ATP-dependent DNA helicase Hrp3 Positive GeneticPMID:22681890
ppk9serine/threonine protein kinase Ppk9 (predicted) Negative GeneticPMID:22681890
crb2DNA repair protein Rad9 homolog, Rhp9 Positive GeneticPMID:22681890
fin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:22681890
SPAC1952.10cconserved fungal protein Negative GeneticPMID:22681890
SPBC3F6.01cserine/threonine protein phosphatase (predicted) Positive GeneticPMID:22681890
set1histone lysine methyltransferase Set1 Positive GeneticPMID:22681890
dmc1RecA family ATPase Dmc1 Negative GeneticPMID:22681890
ste20Rictor homolog, Ste20 Negative GeneticPMID:22681890
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:22681890
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
SPCC1020.07haloacid dehalogenase-like hydrolase Positive GeneticPMID:22681890
atp11F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
gst1glutathione S-transferase Gst1 Negative GeneticPMID:22681890
SPCC1450.09cphospholipase (predicted) Positive GeneticPMID:22681890
mkh1MEK kinase (MEKK) Mkh1 Negative GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
atg6beclin family protein, involved in autophagy Positive GeneticPMID:22681890
dad1DASH complex subunit Dad1 Positive GeneticPMID:22681890
pom1DYRK family protein kinase Pom1 Negative GeneticPMID:22681890
pnk1DNA kinase/phosphatase Pnk1 Negative GeneticPMID:22681890
ppk15serine/threonine protein kinase Ppk15 (predicted) Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPBC725.04 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC725.04 Retrieval of eukaryotic orthologs
BioGrid SPBC725.04 BioGRID Interaction Datasets
Bähler Lab SPBC725.04 Cell Cycle Expression Profile
Bähler Lab SPBC725.04 Meiosis/Sporulation Expression Profies
Bähler Lab SPBC725.04 Pheromone response/mating expression profiles
Bähler Lab SPBC725.04 Environmental stress expression profiles
Bähler Lab SPBC725.04 Bähler Lab Transcriptome Viewer
Cyclebase SPBC725.04 Cell Cycle Data
PInt SPBC725.04 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC725.04 Entrez Gene
SPD / RIKEN36/36B05Orfeome Localization Data
EntrezGene2541142oxalyl-CoA decarboxylase (predicted)
WikiGene2541142oxalyl-CoA decarboxylase (predicted)
UniProtKB/SwissProtQ9Y7M1Putative 2-hydroxyacyl-CoA lyase
ModBaseQ9Y7M1Database of comparative protein structure models
Pfam Protein DomainsQ9Y7M1Pfam Domain Arrangement
RefSeq PeptideNP_595484oxalyl-CoA decarboxylase (predicted)
RefSeq mRNANM_001021395972h- oxalyl-CoA decarboxylase (predicted) (SPBC725.04), mRNA
European Nucleotide ArchiveCAA22176ENA Protein Mapping
SPD / RIKEN36/36B05Orfeome Localization Data

Literature for SPBC725.04
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013