cog6 (SPBC776.10c)

Gene Standard Namecog6 Characterisation Statusbiological role inferred
Systematic IDSPBC776.10c Feature Typeprotein coding
Synonyms Name Description
ProductGolgi transport complex peripheral subunit Cog6 (predicted) Product Size675aa, 77.33 kDa
Genomic Location Chromosome II, 3195791-3193253 (2539nt); CDS:3195569-3193434 (2136nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
intra-Golgi vesicle-mediated transport13
Annotation ExtensionEvidenceWith/FromReference
intracellular protein transport336
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cell division site308
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
Golgi transport complex7
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationcog6Δ1443

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination, single or double cell divisioncog6Δ105
inviable after spore germination, without cell division, with abnormal germ tube morphologycog6Δ153
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3195791..3195309, 3195256..3194295, 3194238..3193253
Intron3195310..3195255, 3194296..3194237
5' UTR3195791..3195570PMID:21511999
CDS3195569..3195309, 3195256..3194295, 3194238..3193434
3' UTR3193433..3193253AU006769
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06419 Pfam Conserved oligomeric Golgi complex subunit 6 44 634 1
SM01087 SMART IPR010490 Conserved oligomeric Golgi complex subunit 6 43 650 1
PTHR21506 HMMPANTHER IPR010490 Conserved oligomeric Golgi complex subunit 6 8 667 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.56 Da
Charge -24.00
Codon Adpatation Index 0.37
Isoelectric point 4.60
Molecular weight 77.33 kDa
Number of residues 675
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
315.42during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
722during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.1during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
0.64during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3090
conserved in fungi4604
conserved in eukaryotes4514
conserved in metazoa3421
conserved in vertebrates3396
conserved in eukaryotes only2503

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPBC776.10c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC776.10c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC776.10c BioGRID Interaction Datasets
Expression Viewer SPBC776.10c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC776.10c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC776.10c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC776.10c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC776.10c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC776.10c Transcriptome Viewer (Bähler Lab)
GEO SPBC776.10c GEO profiles
PInt SPBC776.10c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC776.10c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC776.10c Fission yeast phenotypic data & analysis
Cyclebase SPBC776.10c.1 Cell Cycle Data
SPD / RIKEN37/37E04Orfeome Localization Data
UniProtKB/SwissProtO94677Conserved oligomeric Golgi complex subunit 6
ModBaseO94677Database of comparative protein structure models
STRINGO94677Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596325Golgi transport complex peripheral subunit Cog6 (predicted)
RefSeq mRNANM_001022247972h- Golgi transport complex peripheral subunit Cog6 (predicted) (cog6), mRNA
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveCAA22883ENA Protein Mapping
European Nucleotide ArchiveCAA22883.1ENA Protein Mapping
UniParcUPI000006BB03UniProt Archive

Literature for cog6

Search: Europe PMC or PubMed

Release Version: PomBase:28_55 - 09 Sep 2015