cog6 (SPBC776.10c)


Gene Standard Namecog6 Characterisation Statusbiological_role_inferred
Systematic IDSPBC776.10c Feature Typeprotein coding
Synonyms Name Description
ProductGolgi transport complex peripheral subunit Cog6 (predicted) Product Size675aa, 77.33 kDa
Genomic Location Chromosome II, 3195791-3193253 (2539nt); CDS:3195569-3193434 (2136nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
intra-Golgi vesicle-mediated transport13
Annotation ExtensionEvidenceWith/FromReference
intracellular protein transport340
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cell division site299
Annotation ExtensionEvidenceWith/FromReference
cytosol2316
Annotation ExtensionEvidenceWith/FromReference
Golgi transport complex7
Annotation ExtensionEvidenceWith/FromReference
nucleus2690
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationcog6ΔNull1427

Cell Phenotype

Term NameAlleleExpressionCount
inviable after spore germination, single or double cell division101
penetrance FYPO_EXT:0000003cog6ΔNull
inviable after spore germination, without cell division, with abnormal germ tube morphology150
penetrance FYPO_EXT:0000001cog6ΔNull
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
131957913195309
231952563194295
331942383193253

UTRs

Region Coordinates Reference
five_prime_UTR3195791..3195570PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06419 Pfam IPR010490 Conserved oligomeric Golgi complex subunit 6 44 649 1
SM01087 SMART IPR010490 Conserved oligomeric Golgi complex subunit 6 43 650 1
PTHR21506 HMMPANTHER IPR010490 Conserved oligomeric Golgi complex subunit 6 8 667 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.56 Da
Charge -24.00
Isoelectric point 4.60
Molecular weight 77.33 kDa
Number of residues 675
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
722during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
315.42during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.1during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.64during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3432
conserved in vertebrates3407
conserved in eukaryotes only2503
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPBC776.10c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC776.10c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC776.10c BioGRID Interaction Datasets
Expression Viewer SPBC776.10c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC776.10c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC776.10c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC776.10c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC776.10c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC776.10c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC776.10c Cell Cycle Data
GEO SPBC776.10c GEO profiles
PInt SPBC776.10c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC776.10c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC776.10c Fission yeast phenotypic data & analysis
SPD / RIKEN37/37E04Orfeome Localization Data
UniProtKB/SwissProtO94677Conserved oligomeric Golgi complex subunit 6
ModBaseO94677Database of comparative protein structure models
STRINGO94677Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596325Golgi transport complex peripheral subunit Cog6 (predicted)
RefSeq mRNANM_001022247972h- Golgi transport complex peripheral subunit Cog6 (predicted) (cog6), mRNA
European Nucleotide ArchiveCAA22883.1ENA Protein Mapping
UniParcUPI000006BB03UniProt Archive

Literature for cog6

Search: Europe PMC or PubMed

Release Version: PomBase:25_48 - 10 Jan 2015