cog6 (SPBC776.10c)

Gene Standard Namecog6 Characterisation Statusbiological_role_inferred
Systematic IDSPBC776.10c Feature Typeprotein coding
Synonyms Name Description
ProductGolgi transport complex peripheral subunit Cog6 (predicted) Product Size675aa, 77.33 kDa
Genomic Location Chromosome II, 3195791-3193253 (2539nt); CDS:3195569-3193434 (2136nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006891intra-Golgi vesicle-mediated transportISOSGD:S000004986GO_REF:000002413
GO:0006886intracellular protein transportNASGO_REF:0000051326
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0017119Golgi transport complexISOSGD:S000004986GO_REF:00000247
GO:0032153cell division siteIDAPMID:16823372298
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopycog6ΔNullPECO:0000005, PECO:0000137PMID:236978061337

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001042inviable after spore germination, single or double cell division96
penetrance FYPO_EXT:0000003Microscopycog6ΔNullPECO:0000005, PECO:0000137PMID:23697806
FYPO:0000313inviable after spore germination, without cell division, with abnormal germ tube morphology146
penetrance FYPO_EXT:0000001Microscopycog6ΔNullPECO:0000005, PECO:0000137PMID:23697806
Ensembl transcript structure with UTRs, exons and introns


Exon Start End
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06419 Pfam IPR010490 Conserved oligomeric Golgi complex subunit 6 44 649 1
SM01087 SMART IPR010490 Conserved oligomeric Golgi complex subunit 6 43 650 1
PTHR21506 HMMPANTHER IPR010490 Conserved oligomeric Golgi complex subunit 6 1 665 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.56 Da
Charge -24.00
Isoelectric point 4.60
Molecular weight 77.33 kDa
Number of residues 675
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
315.42during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
722during GO:0072690PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.1during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
0.64during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3092
conserved in fungi4599
conserved in eukaryotes4514
conserved in metazoa3428
conserved in vertebrates3402
conserved in eukaryotes only2498

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
External References
Database Identifier Description
NBRP SPBC776.10c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC776.10c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC776.10c BioGRID Interaction Datasets
Expression Viewer SPBC776.10c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC776.10c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC776.10c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC776.10c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC776.10c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC776.10c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC776.10c Cell Cycle Data
GEO SPBC776.10c GEO profiles
PInt SPBC776.10c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC776.10c Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN37/37E04Orfeome Localization Data
UniProtKB/SwissProtO94677Conserved oligomeric Golgi complex subunit 6
ModBaseO94677Database of comparative protein structure models
STRINGO94677Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596325Golgi transport complex peripheral subunit Cog6 (predicted)
RefSeq mRNANM_001022247972h- Golgi transport complex peripheral subunit Cog6 (predicted) (cog6), mRNA
European Nucleotide ArchiveCAA22883.1ENA Protein Mapping
UniParcUPI000006BB03UniProt Archive

Literature for cog6

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014