cog6 (SPBC776.10c)


Gene Standard Namecog6 Characterisation Statusbiological_role_inferred
Systematic IDSPBC776.10c Feature Typeprotein coding
Synonyms Name Description
ProductGolgi transport complex peripheral subunit Cog6 (predicted) Product Size675aa, 77.33 kDa
Genomic Location Chromosome II, 3195791-3193253 (2539nt); CDS:3195569-3193434 (2136nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006891intra-Golgi vesicle-mediated transportISOSGD:S000004986GO_REF:000002416
GO:0006886intracellular protein transportNASGO_REF:0000051332
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0017119Golgi transport complexISOSGD:S000004986GO_REF:00000247
GO:0032153cell division siteIDAPMID:16823372292
GO:0005829cytosolIDAPMID:168233722317
GO:0016020membraneIEAUniProtKB-KW:KW-0472GO_REF:00000371439
GO:0005634nucleusIDAPMID:168233722730
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopycog6ΔNullPMID:204732891309
Microscopycog6ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001042inviable after spore germination, single or double cell divisionMicroscopycog6ΔNullPECO:0000005, PECO:0000137PMID:2369780691
penetrance FYPO_EXT:0000003
FYPO:0000313inviable after spore germination, without cell division, with abnormal germ tube morphologyMicroscopycog6ΔNullPECO:0000005, PECO:0000137PMID:23697806144
penetrance FYPO_EXT:0000001
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
131957913195309
231952563194295
331942383193253

UTRs

Region Start End Reference
five_prime_UTR31957913195570PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06419 Pfam IPR010490 Conserved oligomeric Golgi complex subunit 6 44 649 1
SM01087 SMART IPR010490 Conserved oligomeric Golgi complex subunit 6 43 650 1
PTHR21506 HMMPANTHER IPR010490 Conserved oligomeric Golgi complex subunit 6 1 665 1
Low complexity (SEG) seg 532 546
Low complexity (SEG) seg 82 97

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.56 Da
Charge -24.00
Isoelectric point 4.60
Molecular weight 77.33 kDa
Number of residues 675
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
315.42during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.64during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
2.1during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in eukaryotes only2485
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
External References
Database Identifier Description
NBRP SPBC776.10c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC776.10c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC776.10c BioGRID Interaction Datasets
Expression Viewer SPBC776.10c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC776.10c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC776.10c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC776.10c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC776.10c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC776.10c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC776.10c Cell Cycle Data
GEO SPBC776.10c GEO profiles
PInt SPBC776.10c Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2541207Golgi transport complex peripheral subunit Cog6 (predicted)
EntrezGene2541207Golgi transport complex peripheral subunit Cog6 (predicted)
SPD / RIKEN37/37E04Orfeome Localization Data
UniProtKB/SwissProtO94677Conserved oligomeric Golgi complex subunit 6
ModBaseO94677Database of comparative protein structure models
StringO94677Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596325Golgi transport complex peripheral subunit Cog6 (predicted)
RefSeq mRNANM_001022247972h- Golgi transport complex peripheral subunit Cog6 (predicted) (cog6), mRNA
European Nucleotide ArchiveCAA22883ENA Protein Mapping
UniParcUPI000006BB03UniProt Archive

Literature for cog6

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014