ucp8 (SPBC83.01)

Gene Standard Nameucp8 ChromosomeII
Systematic IDSPBC83.01 Gene Start1510190
Synonyms Gene End1513963
ProductUBA/EH/EF hand domain protein Ucp8 Gene Length3774
Feature Typeprotein coding CDS Start1510581
Name Description CDS End1513363
Characterisation Statuspublished CDS Length2783

Ensembl Gene Location
  1. shy1
  2. naa25
  3. SPNCRNA.351
  4. ucp8
  5. rpl4302
  6. tas3
  7. apc15
  8. SPBC83.05
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopyucp8delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005509calcium ion bindingISMPFAM:PF00036GO_REF:0000001
GO:0031593polyubiquitin bindingTASPMID:12672455
GO:0043130ubiquitin bindingISMIPR000449GO_REF:0000001
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0000147actin cortical patch assemblyISOSGD:S000001445GO_REF:0000024
GO:0006886intracellular protein transportICGO:0006897GO_REF:0000001
GO:0006897endocytosisISSUniProtKB:P34216GO_REF:0000001
GO:0006898receptor-mediated endocytosisNASPMID:12672455
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0030479actin cortical patchISOSGD:S000000143GO_REF:0000024
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
115101901510730
215108811511004
315110501513235
415133341513963

References

Region Start End Reference
five_prime_UTR15101901510580PMID:21511999
three_prime_UTR15133641513963PMID:21511999
three_prime_UTR15133641513963PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00627 IPR000449 Pfam Ubiquitin-associated/translation elongation factor EF1B, N-terminal 789 825 9
PF12763 Pfam 301 365 4
PF12763 Pfam 156 225 4
SM00027 IPR000261 SMART EPS15 homology (EH) 122 224 4
SM00027 IPR000261 SMART EPS15 homology (EH) 3 89 4
SM00027 IPR000261 SMART EPS15 homology (EH) 293 390 4
SM00054 IPR002048 SMART EF-hand domain 47 75 14
SM00054 IPR002048 SMART EF-hand domain 337 365 14
SM00165 IPR015940 SMART Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote 790 827 7
PS50030 IPR015940 Prosite Profiles Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote 788 828 9
PS50031 IPR000261 Prosite Profiles EPS15 homology (EH) 129 225 5
PS50031 IPR000261 Prosite Profiles EPS15 homology (EH) 10 99 5
PS50031 IPR000261 Prosite Profiles EPS15 homology (EH) 300 386 5
PS50222 IPR018249 Prosite Profiles EF-hand domain 333 368 20
PS50222 IPR018249 Prosite Profiles EF-hand domain 43 78 20
G3DSA:1.10.238.10 IPR011992 Gene3D 107 224 20
G3DSA:1.10.238.10 IPR011992 Gene3D 3 101 20
G3DSA:1.10.238.10 IPR011992 Gene3D 284 378 20
G3DSA:1.10.8.10 Gene3D 779 827 17
SSF46934 IPR009060 SuperFamily 767 828 13
SSF47473 SuperFamily 5 81 21
SSF47473 SuperFamily 294 375 21
SSF47473 SuperFamily 119 223 21
Coil ncoils Rabaptin coiled-coil domain 636 670 974
Coil ncoils Rabaptin coiled-coil domain 604 625 974
Coil ncoils Rabaptin coiled-coil domain 688 709 974
PTHR11216:SF46 hmmpanther 4 378 2
PTHR11216 hmmpanther 4 378 6

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000276EF handTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000276
PBO:0000794UBA domain proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000794
PBO:0003116EH domainsTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0003116

Sequence Ontology

Term IDTerm NameReference
SO:0001080coiled_coil

Protein Properties

Ave. residue weight 109.91 Da
Charge -41.00
Isoelectric point 4.43
Molecular weight 91.12 kDa
Number of residues 829
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide6331.51PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide7714.8PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.5PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide5.6PMID:23101633
Warning
DescriptionQualifierReference
gene structure updated PMID:21511999
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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External References
Database Identifier Description
NBRP SPBC83.01 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC83.01 Retrieval of eukaryotic orthologs
BioGrid SPBC83.01 BioGRID Interaction Datasets
Bähler Lab SPBC83.01 Cell Cycle Expression Profile
Bähler Lab SPBC83.01 Meiosis/Sporulation Expression Profies
Bähler Lab SPBC83.01 Pheromone response/mating expression profiles
Bähler Lab SPBC83.01 Environmental stress expression profiles
Bähler Lab SPBC83.01 Bähler Lab Transcriptome Viewer
Cyclebase SPBC83.01 Cell Cycle Data
PInt SPBC83.01 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPBC83.01 Entrez Gene
WikiGene2540786UBA/EH/EF hand domain protein Ucp8
Uniprot_genenameUCP8
EntrezGene2540786UBA/EH/EF hand domain protein Ucp8
SPD / RIKEN29/29F01Orfeome Localization Data
UniProtKB/SwissProtO94685UBA domain-containing protein 8
ModBaseO94685Database of comparative protein structure models
Pfam Protein DomainsO94685Pfam Domain Arrangement
RefSeq PeptideNP_595633UBA/EH/EF hand domain protein Ucp8
RefSeq mRNANM_001021527972h- UBA/EH/EF hand domain protein Ucp8 (ucp8), mRNA
European Nucleotide ArchiveCAB36863ENA Protein Mapping
UniParcUPI000228F3B6UniProt Archive

Literature for ucp8
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013