rpl803 (SPBC839.04)


Gene Standard Namerpl803 Characterisation Statusbiological_role_inferred
Systematic IDSPBC839.04 Feature Typeprotein coding
Synonymsrpk5-b, rpkD4, rpl8-3, SPBC24E9.04 Name Description
Product60S ribosomal protein L8 (predicted) Product Size253aa, 27.10 kDa
Genomic Location Chromosome II, 601209-602186 (978nt); CDS:601281-602042 (762nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0019843rRNA bindingISMPFAM:PF00181GO_REF:000000146
GO:0003735structural constituent of ribosomeISOSGD:S000001280GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002181cytoplasmic translationNASGO_REF:0000051445
GO:0006412translationISOSGD:S000001280GO_REF:0000024597
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722316
GO:0022625cytosolic large ribosomal subunitISOSGD:S000001280GO_REF:000002482
GO:0005634nucleusIDAPMID:168233722740
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001701sensitive to bortezomib256
expressivity FYPO_EXT:0000003Cell growth assayrpl803ΔNullPECO:0000005, PECO:0000137PMID:21760946
FYPO:0002060viable vegetative cell populationMicroscopyrpl803ΔNullPMID:204732893730
Microscopyrpl803ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyrpl803ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1601209602186

UTRs

Region Coordinates Reference
five_prime_UTR601209..601280PMID:21511999
three_prime_UTR602043..602186PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00181 Pfam IPR022666 Ribosomal Proteins L2, RNA binding domain 15 89 4
PF03947 Pfam IPR022669 Ribosomal protein L2, C-terminal 96 228 4
PS00467 Prosite Patterns IPR022671 Ribosomal protein L2, conserved site 196 207 4
PTHR13691 HMMPANTHER IPR002171 Ribosomal protein L2 1 253 4
PTHR13691:SF16 HMMPANTHER 1 253 3
2.40.50.140 Gene3D IPR012340 Nucleic acid-binding, OB-fold 1 85 48
4.10.950.10 Gene3D IPR014726 Ribosomal protein L2, domain 3 169 243 4
2.30.30.30 Gene3D IPR014722 Ribosomal protein L2 domain 2 89 168 13
SSF50249 SuperFamily IPR012340 Nucleic acid-binding, OB-fold 2 96 57
SSF50104 SuperFamily IPR008991 Translation protein SH3-like domain 98 244 16
PIRSF002158 PIRSF IPR002171 Ribosomal protein L2 1 253 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 107.12 Da
Charge 29.50
Isoelectric point 11.45
Molecular weight 27.10 kDa
Number of residues 253
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
52during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
8during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4569
conserved in eukaryotes4482
conserved in bacteria1001
conserved in metazoa3419
conserved in vertebrates3393
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
nak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
cid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
air1zinc knuckle TRAMP complex subunit Air1 Affinity Capture-MSPMID:20403971
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
External References
Database Identifier Description
NBRP SPBC839.04 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC839.04 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC839.04 BioGRID Interaction Datasets
Expression Viewer SPBC839.04 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC839.04 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC839.04 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC839.04 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC839.04 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC839.04 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC839.04 Cell Cycle Data
GEO SPBC839.04 GEO profiles
PInt SPBC839.04 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC839.04 Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN09/09D05Orfeome Localization Data
EntrezGene254036660S ribosomal protein L8
EntrezGene254119160S ribosomal protein L8
EntrezGene580295260S ribosomal protein L8
WikiGene254036660S ribosomal protein L8
WikiGene254119160S ribosomal protein L8
WikiGene580295260S ribosomal protein L8
UniProtKB/SwissProtP0809360S ribosomal protein L2
ModBaseP08093Database of comparative protein structure models
STRINGP08093Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59524460S ribosomal protein L8
RefSeq mRNANM_001021150972h- 60S ribosomal protein L8 (rpl803), mRNA
European Nucleotide ArchiveBAA87149ENA Protein Mapping
European Nucleotide ArchiveBAA87149.1ENA Protein Mapping
European Nucleotide ArchiveCAA28710ENA Protein Mapping
European Nucleotide ArchiveCAA28710.1ENA Protein Mapping
European Nucleotide ArchiveCAA34428ENA Protein Mapping
European Nucleotide ArchiveCAA34428.1ENA Protein Mapping
European Nucleotide ArchiveCAA35971ENA Protein Mapping
European Nucleotide ArchiveCAA35971.1ENA Protein Mapping
European Nucleotide ArchiveCAA91960ENA Protein Mapping
European Nucleotide ArchiveCAA91960.1ENA Protein Mapping
European Nucleotide ArchiveCAB10155ENA Protein Mapping
European Nucleotide ArchiveCAB10155.1ENA Protein Mapping
European Nucleotide ArchiveCAB46697ENA Protein Mapping
European Nucleotide ArchiveCAB46697.1ENA Protein Mapping
ReactomeREACT_188294
ReactomeREACT_188542
ReactomeREACT_188560
ReactomeREACT_206850
ReactomeREACT_215930
UniParcUPI0000133ED3UniProt Archive

Literature for rpl803

Search: Europe PMC or PubMed

Release Version: PomBase:22_45 - 08 Aug 2014