lub1 (SPBC887.04c)


Gene Standard Namelub1 Characterisation Statuspublished
Systematic IDSPBC887.04c Feature Typeprotein coding
Synonyms Name Description
ProductWD repeat protein Lub1 Product Size718aa, 79.22 kDa
Genomic Location Chromosome II, 3548655-3546128 (2528nt); CDS:3548505-3546238 (2268nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
protein binding856
Annotation ExtensionEvidenceWith/FromReference
ubiquitin binding23
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
DNA repair163
Annotation ExtensionEvidenceWith/FromReference
histone ubiquitination5
Annotation ExtensionEvidenceWith/FromReference
proteasome-mediated ubiquitin-dependent protein catabolic process136
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytoplasm4207
Annotation ExtensionEvidenceWith/FromReference
nucleus2695
Annotation ExtensionEvidenceWith/FromReference
protein complex1368
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
normal growth on cisplatinlub1ΔNull39
sensitive to cobaltlub1ΔNull56
viable vegetative cell populationlub1ΔNull3795

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologylub1ΔNull3093
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3548655..3548458, 3548391..3548220, 3548174..3546128
mRNA3548655..3546128
5' UTR3548655..3548506PMID:21511999
CDS3548505..3548458, 3548391..3548220, 3548174..3546238
3' UTR3546237..3546128PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00400 Pfam IPR001680 WD40 repeat 51 83 104
PF00400 Pfam IPR001680 WD40 repeat 172 206 104
PF00400 Pfam IPR001680 WD40 repeat 99 129 104
PF00400 Pfam IPR001680 WD40 repeat 211 248 104
PF00400 Pfam IPR001680 WD40 repeat 7 41 104
PF00400 Pfam IPR001680 WD40 repeat 132 169 104
PF00400 Pfam IPR001680 WD40 repeat 251 286 104
PF08324 Pfam IPR013535 PUL 463 714 1
PF09070 Pfam IPR015155 PLAA family ubiquitin binding, PFU 332 443 1
SM00320 SMART IPR001680 WD40 repeat 249 287 112
SM00320 SMART IPR001680 WD40 repeat 209 248 112
SM00320 SMART IPR001680 WD40 repeat 170 207 112
SM00320 SMART IPR001680 WD40 repeat 3 41 112
SM00320 SMART IPR001680 WD40 repeat 131 169 112
SM00320 SMART IPR001680 WD40 repeat 45 88 112
SM00320 SMART IPR001680 WD40 repeat 92 130 112
PS51394 Prosite Profiles IPR015155 PLAA family ubiquitin binding, PFU 353 448 1
PS51396 Prosite Profiles IPR013535 PUL 462 717 1
PS50082 Prosite Profiles IPR001680 WD40 repeat 216 248 100
PS50082 Prosite Profiles IPR001680 WD40 repeat 138 169 100
PS50082 Prosite Profiles IPR001680 WD40 repeat 99 129 100
PS50294 Prosite Profiles IPR017986 WD40-repeat-containing domain 10 257 104
PTHR19849 HMMPANTHER 1 718 1
PTHR19849:SF0 HMMPANTHER 1 718 1
2.130.10.10 Gene3D IPR015943 WD40/YVTN repeat-like-containing domain 6 314 145
SSF50978 SuperFamily IPR017986 WD40-repeat-containing domain 3 298 135
SSF48371 SuperFamily IPR016024 Armadillo-type fold 477 679 130

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000190WD repeat proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000190

Protein Properties

Ave. residue weight 110.34 Da
Charge -14.00
Isoelectric point 4.98
Molecular weight 79.22 kDa
Number of residues 718
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
32525during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
34231during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
32757during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
34746during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
34857during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
6745.07during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
4672.46during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.1during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.57during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999432
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity capturescdc48AAA family ATPase involved in ubiquitin-mediated protein degradation Cdc48 Affinity Capture-WesternPMID:14993272
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withadn2transcription factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withado1adenosine kinase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withaip1actin cortical patch component Aip1 Negative GeneticPMID:22681890
negative genetic interaction withair1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:18818364
negative genetic interaction withamo1nuclear rim protein Amo1 Negative GeneticPMID:18818364
negative genetic interaction withapc10anaphase-promoting complex substrate recognition subunit Apc10 Negative GeneticPMID:22681890
negative genetic interaction witharb1argonaute inhibitor protein 1 Negative GeneticPMID:22681890
positive genetic interaction witharp42SWI/SNF and RSC complex subunit Arp42 Positive GeneticPMID:18818364
negative genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:18818364
negative genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:22681890
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
negative genetic interaction withatp14F1-ATPase subunit H (predicted) Negative GeneticPMID:22681890
positive genetic interaction withbun107WD repeat protein, human WDR48 family Bun107 Positive GeneticPMID:22681890
negative genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withcid12poly(A) polymerase Cid12 Negative GeneticPMID:18818364
negative genetic interaction withcip2RNA-binding protein Cip2 Negative GeneticPMID:22681890
positive genetic interaction withcmk2MAPK-activated protein kinase Cmk2 Positive GeneticPMID:22681890
negative genetic interaction withcwf21complexed with Cdc5 protein Cwf21 Negative GeneticPMID:22681890
negative genetic interaction withdad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
negative genetic interaction withdad2DASH complex subunit Dad2 Negative GeneticPMID:18818364
negative genetic interaction withdad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
negative genetic interaction withdad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
negative genetic interaction withdam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
negative genetic interaction withdbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:22681890
negative genetic interaction withddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
negative genetic interaction withdsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
negative genetic interaction withduo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
positive genetic interaction withelp1elongator subunit Elp1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withelp3elongator complex subunit Elp3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction witheme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:22681890
positive genetic interaction withepe1Jmjc domain chromatin associated protein Epe1 Positive GeneticPMID:18818364
positive genetic interaction withepe1Jmjc domain chromatin associated protein Epe1 Positive GeneticPMID:22681890
positive genetic interaction witherd1Erd1 homolog (predicted) Positive GeneticPMID:22681890
negative genetic interaction witherf4palmitoyltransferase complex subunit Erf4 Negative GeneticPMID:22681890
positive genetic interaction witherg5C-22 sterol desaturase Erg5 Positive GeneticPMID:18818364
positive genetic interaction witherp2COPII-coated vesicle component Erp2/3/4 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withexo1exonuclease I Exo1 Negative GeneticPMID:22681890
negative genetic interaction withfar10SIP/FAR complex FHA domain subunit Far10/Csc1 Negative GeneticPMID:22681890
positive genetic interaction withfft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Positive GeneticPMID:18818364
synthetic growth defect withfor3formin For3 Synthetic Growth DefectPMID:18931302
positive genetic interaction withftp105Ubp5 interacting protein Ftp105 Positive GeneticPMID:22681890
negative genetic interaction withgar2nucleolar protein required for rRNA processing Negative GeneticPMID:22681890
positive genetic interaction withgcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Positive GeneticPMID:18818364
positive genetic interaction withgim3prefoldin subunit 4, Gim3 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withgit3G-protein coupled receptor Git3 Positive GeneticPMID:22681890
negative genetic interaction withglc8protein phosphatase regulatory subunit Glc8 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgld1mitochondrial glycerol dehydrogenase Gld1 Negative GeneticPMID:22681890
negative genetic interaction withgms1UDP-galactose transmembrane transporter Gms1 Negative GeneticPMID:22681890
positive genetic interaction withgyp1GTPase activating protein Gyp1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withhap2HMG box protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
negative genetic interaction withhrq1RecQ type DNA helicase Hrq1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withhrq1RecQ type DNA helicase Hrq1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withhrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:18818364
positive genetic interaction withhul5HECT-type ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withidn1gluconokinase Positive GeneticPMID:22681890
positive genetic interaction withiwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withiwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withkap113karyopherin Kap113 Positive GeneticPMID:18818364
positive genetic interaction withkap114karyopherin Kap14 Positive GeneticPMID:18818364
negative genetic interaction withklp6kinesin-like protein Klp6 Negative GeneticPMID:22681890
negative genetic interaction withlag1sphingosine N-acyltransferase Lag1 Negative GeneticPMID:22681890
positive genetic interaction withlsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Positive GeneticPMID:18818364
positive genetic interaction withlsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Positive GeneticPMID:22681890
negative genetic interaction withmet8siroheme synthase Met8 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmex67mRNA export receptor, Tap, nucleoporin Mex67 Negative GeneticPMID:22681890
positive genetic interaction withmfm3M-factor precursor Mfm3 Positive GeneticPMID:22681890
negative genetic interaction withmms1E3 ubiquitin ligase complex subunit Mms1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withmoc3transcription factor Moc3 Positive GeneticPMID:22681890
negative genetic interaction withmrc1mediator of replication checkpoint 1 Negative GeneticPMID:18818364
negative genetic interaction withmre11Mre11 nuclease Negative GeneticPMID:18818364
negative genetic interaction withmug123Schizosaccharomyces specific protein Mug123 Negative GeneticPMID:22681890
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:18818364
negative genetic interaction withmug65spore wall assembly protein Mug65 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withmug80cyclin Clg1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withmxr2peptide-methionine (R)-S-oxide reductase MsrB Negative GeneticPMID:22681890
negative genetic interaction withmyo51myosin type V Negative GeneticPMID:18818364
positive genetic interaction withngg1SAGA complex subunit Ngg1 Positive GeneticPMID:18818364
negative genetic interaction withnop10snoRNP pseudouridylase box H/ACA snoRNP complex protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnot2CCR4-Not complex subunit Not2 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withnot2CCR4-Not complex subunit Not2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnot3CCR4-Not complex subunit Not3/5 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withnot3CCR4-Not complex subunit Not3/5 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withnsk1Clp1-interacting, microtubule plus-end binding Nsk1 Positive GeneticPMID:22681890
negative genetic interaction withnup132nucleoporin Nup132 Negative GeneticPMID:22681890
negative genetic interaction withotu1ubiquitin-specific cysteine protease, OTU family, Otu1 Negative GeneticPMID:22681890
negative genetic interaction withpds5mitotic cohesin-associated protein Pds5 Negative GeneticPMID:22681890
positive genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:18818364
positive genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:22681890
positive genetic interaction withpmc2mediator complex subunit Pmc2/Med1 Positive GeneticPMID:18818364
negative genetic interaction withpng2ING family homolog Png2 Negative GeneticPMID:22681890
negative genetic interaction withpop2F-box/WD repeat protein Pop2 Negative GeneticPMID:22681890
positive genetic interaction withppk6serine/threonine protein kinase Ppk6 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withprw1Clr6 histone deacetylase complex subunit Prw1 Positive GeneticPMID:22681890
negative genetic interaction withpsh3ER chaperone SHR3 homologue Psh3 Negative GeneticPMID:22681890
negative genetic interaction withpsk1serine/threonine protein kinase Psk1 Negative GeneticPMID:22681890
negative genetic interaction withpsy2protein phosphatase PP4 complex subunit Psy2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrad51RecA family recombinase Rad51/Rhp51 Negative GeneticPMID:22681890
negative genetic interaction withrad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
negative genetic interaction withrad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:22681890
negative genetic interaction withraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Negative GeneticPMID:18818364
negative genetic interaction withrcd1RNA-binding protein, CCR4-NOT complex subunit Rcd1 Negative GeneticPMID:18818364
positive genetic interaction withrds1conserved fungal protein Positive GeneticPMID:22681890
negative genetic interaction withrec14Ski complex subunit Rec14 Negative GeneticPMID:18818364
negative genetic interaction withres1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
phenotype enhanced byrfp2SUMO-targeted ubiquitin-protein ligase subunit Rfp2 Phenotypic EnhancementPMID:19547744
negative genetic interaction withrhn1RNA polymerase II transcription termination factor homolog Negative GeneticPMID:22681890
positive genetic interaction withrhp26SNF2 family ATP-dependent DNA helicase Rhp26 Positive GeneticPMID:22681890
negative genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:18818364
negative genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:22681890
positive genetic interaction withrpb9DNA-directed RNA polymerase II complex subunit Rpb9 Positive GeneticPMID:22681890
negative genetic interaction withrpl160160S ribosomal protein L13/L16 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withrpl160160S ribosomal protein L13/L16 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpl190260S ribosomal protein L19 Negative GeneticPMID:22681890
negative genetic interaction withrpl240160S ribosomal protein L24 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpl270160S ribosomal protein L27 Negative GeneticPMID:22681890
positive genetic interaction withrpl430260S ribosomal protein L37a (predicted) Positive GeneticPMID:22681890
negative genetic interaction withrps280240S ribosomal protein S28, Rps2802 Negative GeneticPMID:22681890
negative genetic interaction withryh1GTPase Ryh1 Negative GeneticPMID:18818364
negative genetic interaction withryh1GTPase Ryh1 Negative GeneticPMID:22681890
negative genetic interaction withscs7sphingosine hydroxylase Scs7 Negative GeneticPMID:18818364
negative genetic interaction withscs7sphingosine hydroxylase Scs7 Negative GeneticPMID:22681890
negative genetic interaction withsdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Negative GeneticPMID:22681890
negative genetic interaction withsds23PP2A-type phosphatase inhibitor Sds23/Moc1 Negative GeneticPMID:22681890
positive genetic interaction withsec28coatomer epsilon subunit (predicted) Positive GeneticPMID:18818364
positive genetic interaction withset1histone lysine methyltransferase Set1 Positive GeneticPMID:18818364
positive genetic interaction withset1histone lysine methyltransferase Set1 Positive GeneticPMID:22681890
positive genetic interaction withsfp1transcription factor Sfp1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withsft1SNARE Sft1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withsif1Sad1 interacting factor 1 Positive GeneticPMID:22681890
positive genetic interaction withsno1glutamine aminotransferase subunit Sno1 (predicted) Positive GeneticPMID:22681890
phenotype enhanced bysnt1Set3 complex subunit Snt1 Phenotypic EnhancementPMID:19547744
negative genetic interaction withSPAC11D3.155-oxoprolinase (ATP-hydrolizing) (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC1952.06cspliceosomal complex subunit (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC1952.09cacetyl-CoA hydrolase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC19B12.11czinc finger protein, human ZNF593 ortholog Negative GeneticPMID:18818364
negative genetic interaction withSPAC19B12.11czinc finger protein, human ZNF593 ortholog Negative GeneticPMID:22681890
negative genetic interaction withSPAC1F5.03cFAD-dependent oxidoreductase involved in late endosome to Golgi transport (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC23H4.13cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC24B11.05pyrimidine 5'-nucleotidase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC343.06cphospholipid scramblase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPAC3G9.11cpyruvate decarboxylase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPAC4G8.04GTPase activating protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC4G9.19DNAJ domain protein DNAJB family (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC56F8.02AMP binding enzyme (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC926.06cleucine-rich repeat protein, unknown role Negative GeneticPMID:22681890
negative genetic interaction withSPAPB1E7.11cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC14C8.15triglyceride lipase-cholesterol esterase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC15C4.04camino acid transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:22681890
negative genetic interaction withSPBC17A3.06phosphoprotein phosphatase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC25B2.10Usp (universal stress protein) family protein Positive GeneticPMID:22681890
negative genetic interaction withSPBC2A9.03WD40/YVTN repeat-like Negative GeneticPMID:18818364
negative genetic interaction withSPBC56F2.08cRNA-binding protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPBC56F2.08cRNA-binding protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withspc19DASH complex subunit Spc19 Negative GeneticPMID:22681890
negative genetic interaction withSPCC18B5.10cTREX complex subunit Tex1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC1919.05Ski complex TPR repeat subunit Ski3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPCC569.04Schizosaccharomyces pombe specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC594.01DUF1769 family protein Negative GeneticPMID:22681890
negative genetic interaction withspn2mitotic and meiotic (sporulation) septin Spn2 Negative GeneticPMID:22681890
negative genetic interaction withste20Rictor homolog, Ste20 Negative GeneticPMID:22681890
negative genetic interaction withsts5RNB-like protein Negative GeneticPMID:22681890
negative genetic interaction withsub1transcription coactivator PC4 Negative GeneticPMID:22681890
negative genetic interaction withsum2G2/M transition checkpoint protein Sum2 Negative GeneticPMID:22681890
positive genetic interaction withswc5Swr1 complex subunit Swc5 Positive GeneticPMID:18818364
negative genetic interaction withswd2Set1C complex subunit Swd2.1 Negative GeneticPMID:22681890
negative genetic interaction withsyn1synaptotagmin family C2 domain protein, Syn1 Negative GeneticPMID:22681890
negative genetic interaction withtal1transaldolase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withtas3RITS complex subunit 3 Negative GeneticPMID:18818364
synthetic growth defect withtea2kinesin-like protein Tea2 Synthetic Growth DefectPMID:18931302
rescued bytif213translation initiation factor eIF2 gamma subunit Phenotypic SuppressionPMID:19547744
negative genetic interaction withtma23ribosome biogenesis protein Tma23 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withtom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withtrk2potassium ion transmembrane transporter Trk2 Negative GeneticPMID:22681890
positive genetic interaction withuba42thiosulfate sulfurtransferase, URM1 activating enzyme E1-type Uba42 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withubc13ubiquitin conjugating enzyme E2 Ubc13 Negative GeneticPMID:22681890
positive genetic interaction withubc6ubiquitin conjugating enzyme E2 Ubc6 (predicted) Positive GeneticPMID:18818364
negative genetic interaction withubp6ubiquitin C-terminal hydrolase Ubp6 Negative GeneticPMID:18818364
positive genetic interaction withubp8SAGA complex ubiquitin C-terminal hydrolase Ubp8 Positive GeneticPMID:18818364
positive genetic interaction withufd2ubiquitin-protein ligase E4 Ufd2 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withufd2ubiquitin-protein ligase E4 Ufd2 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withuge1UDP-glucose 4-epimerase Uge1 Positive GeneticPMID:22681890
positive genetic interaction withulp2SUMO deconjugating cysteine peptidase Ulp2 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withusp103U1 snRNP-associated protein Usp103 Negative GeneticPMID:18818364
negative genetic interaction withvht1vitamin H transmembrane transporter Vht1 Negative GeneticPMID:22681890
negative genetic interaction withvph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Negative GeneticPMID:18818364
negative genetic interaction withvph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withvps71Swr1 complex subunit Vps71 Positive GeneticPMID:18818364
positive genetic interaction withyox1MBF complex corepressor Yox1 Positive GeneticPMID:22681890
negative genetic interaction withypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPBC887.04c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC887.04c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC887.04c BioGRID Interaction Datasets
Expression Viewer SPBC887.04c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC887.04c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC887.04c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC887.04c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC887.04c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC887.04c Transcriptome Viewer (Bähler Lab)
GEO SPBC887.04c GEO profiles
PInt SPBC887.04c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC887.04c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC887.04c Fission yeast phenotypic data & analysis
Cyclebase SPBC887.04c.1 Cell Cycle Data
SPD / RIKEN28/28B06Orfeome Localization Data
UniProtKB/SwissProtO94289Ubiquitin homeostasis protein lub1
ModBaseO94289Database of comparative protein structure models
STRINGO94289Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596478WD repeat protein Lub1
RefSeq mRNANM_001022398972h- WD repeat protein Lub1 (lub1), mRNA
European Nucleotide ArchiveCAA21889.2ENA Protein Mapping
UniParcUPI000228F3C3UniProt Archive

Literature for lub1

Search: Europe PMC or PubMed

Release Version: PomBase:26_51 - 07 Apr 2015