snx3 (SPBC887.06c)


Gene Standard Namesnx3 Characterisation Statusbiological_role_inferred
Systematic IDSPBC887.06c Feature Typeprotein coding
Synonymsgrd19 Name Description
Productsorting nexin Snx3 (predicted) Product Size143aa, 16.96 kDa
Genomic Location Chromosome II, 3550817-3549995 (823nt); CDS:3550635-3550020 (616nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0032266phosphatidylinositol-3-phosphate bindingISOSGD:S000005884GO_REF:000002413
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006886intracellular protein transportISOSGD:S000005884GO_REF:0000024330
GO:0034499late endosome to Golgi transportISOSGD:S000005884GO_REF:00000241
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005794Golgi apparatusIEAUniProtKB-KW:KW-0333GO_REF:0000037355
GO:0005829cytosolIDAPMID:168233722316
GO:0005768endosomeISOSGD:S000005884GO_REF:000002478
GO:0031902late endosome membraneIEASL-0224GO_REF:00000398
GO:0005634nucleusIDAPMID:168233722740
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopysnx3ΔNullPECO:0000005, PECO:0000137PMID:236978063760
Microscopysnx3ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3086
penetrance FYPO_EXT:0000001Microscopysnx3ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
135508173550552
235505023550437
335503813550185
435501043549995

UTRs

Region Coordinates Reference
five_prime_UTR3550817..3550636PMID:21511999
three_prime_UTR3550019..3549995PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00787 Pfam IPR001683 Phox homologous domain 23 136 14
SM00312 SMART IPR001683 Phox homologous domain 22 137 14
PS50195 Prosite Profiles IPR001683 Phox homologous domain 23 140 11
PTHR10555 HMMPANTHER 5 138 8
3.30.1520.10 Gene3D IPR001683 Phox homologous domain 21 138 14
SSF64268 SuperFamily IPR001683 Phox homologous domain 22 139 14

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000462PX domain proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000462

Protein Properties

Ave. residue weight 118.61 Da
Charge 4.50
Isoelectric point 9.10
Molecular weight 16.96 kDa
Number of residues 143
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
3575.29during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
7139.64during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
32438during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
1.9during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
0.86during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in eukaryotes only2487
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPBC887.06c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC887.06c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC887.06c BioGRID Interaction Datasets
Expression Viewer SPBC887.06c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC887.06c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC887.06c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC887.06c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC887.06c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC887.06c Transcriptome Viewer (Bähler Lab)
Cyclebase SPBC887.06c Cell Cycle Data
GEO SPBC887.06c GEO profiles
PInt SPBC887.06c Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2541210sorting nexin Snx3
EntrezGene2541210sorting nexin Snx3
SPD / RIKEN06/06H08Orfeome Localization Data
UniProtKB/SwissProtO94291Sorting nexin-3
ModBaseO94291Database of comparative protein structure models
STRINGO94291Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596480sorting nexin Snx3
RefSeq mRNANM_001022400972h- sorting nexin Snx3 (snx3), mRNA
European Nucleotide ArchiveCAA21891ENA Protein Mapping
European Nucleotide ArchiveCAA21891.1ENA Protein Mapping
UniParcUPI000006B52CUniProt Archive

Literature for snx3

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014