snx3 (SPBC887.06c)

Gene Standard Namesnx3 Characterisation Statusbiological role inferred
Systematic IDSPBC887.06c Feature Typeprotein coding
Synonymsgrd19 Name Description
Productsorting nexin Snx3 (predicted) Product Size143aa, 16.96 kDa
Genomic Location Chromosome II, 3550817-3549995 (823nt); CDS:3550635-3550020 (616nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
phosphatidylinositol-3-phosphate binding12
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
intracellular protein transport373
Annotation ExtensionEvidenceWith/FromReference
late endosome to Golgi transport1
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
Golgi apparatus358
Annotation ExtensionEvidenceWith/FromReference
late endosome membrane8
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
sensitive to 5-fluorouracilsnx3Δ307
viable spore populationsnx3Δ46
viable vegetative cell populationsnx3Δ3862

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologysnx3Δ3103
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3550817..3550552, 3550502..3550437, 3550381..3550185, 3550104..3549995
Intron3550551..3550503, 3550436..3550382, 3550184..3550105
5' UTR3550817..3550636PMID:21511999
CDS3550635..3550552, 3550502..3550437, 3550381..3550185, 3550104..3550020
3' UTR3550019..3549995PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00787 Pfam IPR001683 Phox homologous domain 23 136 14
SM00312 SMART IPR001683 Phox homologous domain 22 137 13
PS50195 Prosite Profiles IPR001683 Phox homologous domain 23 140 11
PTHR10555 HMMPANTHER 5 141 8
3.30.1520.10 Gene3D IPR001683 Phox homologous domain 21 138 14
SSF64268 SuperFamily IPR001683 Phox homologous domain 22 139 13

View domain organization at Pfam

Term IDTerm NameReferenceCount
PBO:0000462PX domain proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000462

Protein Properties

Ave. residue weight 118.61 Da
Charge 4.50
Codon Adaptation Index 0.46
Isoelectric point 9.10
Molecular weight 16.96 kDa
Number of residues 143

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS68, S136 2293
Annotation ExtensionEvidenceResidueReference
IDA S68 PMID:25720772
IDA S136 PMID:25720772
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for snx3 (SPBC887.06c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3575.29during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
32438during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
7139.64during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.9during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
0.86during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
conserved in fungi4608
conserved in eukaryotes4516
conserved in metazoa3498
conserved in vertebrates3473
conserved in eukaryotes only2525

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Load genes that interact physically with SPBC887.06c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
binds activation domain construct withyop1ER membrane protein DP1/Yop1 Two-hybridPMID:26771498
binds DNA-binding domain construct withckb2CK2 family regulatory subunit Ckb2 (predicted) Two-hybridPMID:26771498
External References
Database Identifier Description
NBRP SPBC887.06c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBC887.06c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBC887.06c BioGRID Interaction Datasets
Expression Viewer SPBC887.06c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBC887.06c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBC887.06c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBC887.06c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBC887.06c Polyadenylation Viewer (Gullerova lab)
pombeTV SPBC887.06c Transcriptome Viewer (Bähler Lab)
GEO SPBC887.06c GEO profiles
PInt SPBC887.06c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBC887.06c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBC887.06c Fission yeast phenotypic data & analysis
Cyclebase SPBC887.06c.1 Cell Cycle Data
SPD / RIKEN06/06H08Orfeome Localization Data
UniProtKB/SwissProtO94291Sorting nexin-3
ModBaseO94291Database of comparative protein structure models
STRINGO94291Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596480sorting nexin Snx3 (predicted)
RefSeq mRNANM_001022400972h- sorting nexin Snx3 (predicted) (snx3), mRNA
European Nucleotide ArchiveCAA21891.1ENA Protein Mapping
UniParcUPI000006B52CUniProt Archive

Literature for snx3

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017