tlh2 (SPBCPT2R1.08c)

Synonyms ChromosomeII
ProductRecQ type DNA helicase Tlh1 Gene Start4526885
Feature Typeprotein coding Gene End4532899
Name Description CDS Start4526885
Characterisation Statuspublished CDS End4532644

Ensembl Gene Location
SPBCPT2R1.07c SPBCPT2R1.10 > tlh2 <
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
145268854532899

Protein Feature Information
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Protein Features

Ensembl protein image with mapped locations of structural domains
Feature ID Database Description Start End Score All Genes
PF00271 Pfam Helicase, C-terminal 1444 1516 54.1 69
PF00270 Pfam DNA/RNA helicase, DEAD/DEAH box type, N-terminal 1202 1362 44.2 43
PF12013 Pfam Protein of unknown function DUF3505 158 347 28.5 2
52540 Superfamily 1199 1527 146.3 295
SM00343 Smart Zinc finger, CCHC-type 1805 1821 23.1 9
SM00490 Smart Helicase, C-terminal 1429 1516 75.7 67
SM00487 Smart Helicase, superfamily 1/2, ATP-binding domain 1189 1389 56.7 70
TMHMM tmhmm Double transmembrane domain 1890 1911 0.72609 1312
PS50158 PROSITE Zinc finger, CCHC-type 1806 1820 9.092 7
PS51192 PROSITE Helicase, superfamily 1/2, ATP-binding domain 1200 1375 13.86 69
PS51194 PROSITE Helicase, C-terminal 1401 1559 17.575 69

Protein Properties

Ave. residue weight 114.32 Da
Charge 9.50
Isoelectric point 6.83
Molecular weight 219.38 kDa
Number of residues 1919
Sequence
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Fission Yeast Phenotype

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Term IDDescriptionSourceAll Genes
FYPO:0000124viableTemporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000124

Gene Ontology Annotations

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Cellular Component
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0000781chromosome, telomeric regionIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0000781

Molecular Function
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0005524ATP bindingIEAGO_REF:0000002Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005524
IEAGO_REF:0000004
GO:0008270zinc ion bindingIEAGO_REF:0000002Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0008270
GO:0043140ATP-dependent 3'-5' DNA helicase activityTASTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0043140

Gene Expression

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DescriptionSourceAll Genes
transcriptionally repressed by Taz1 Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000052
transcriptionally repressed by Rik1 Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000051
transcriptionally repressed by Chp1 Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000050

Genome Organisation

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DescriptionSourceAll Genes
present at telomere ends Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000053

Protein Family

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DescriptionSourceAll Genes
dh repeats Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000054

Species Distribution

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DescriptionSourceAll Genes
conserved in Fungi onlyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000056
conserved in FungiTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000057
conserved in EukaryotesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000058
no apparent S. cerevisiae orthologTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000055


External References

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Database Identifier Description
NBRP SPBCPT2R1.08c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBCPT2R1.08c Retrieval of eukaryotic orthologs
BioGrid SPBCPT2R1.08c BioGRID Interaction Datasets
Bähler Lab SPBCPT2R1.08c Cell Cycle Expression Profile
Bähler Lab SPBCPT2R1.08c Meiosis/Sporulation Expression Profies
Bähler Lab SPBCPT2R1.08c Pheromone response/mating expression profiles
Bähler Lab SPBCPT2R1.08c Environmental stress expression profiles
Bähler Lab SPBCPT2R1.08c Bähler Lab Transcriptome Viewer
Cyclebase SPBCPT2R1.08c Cell Cycle Data
Entrez Gene SPBCPT2R1.08c Link to Entrez Gene
SPD / RIKEN52/52C12Orfeome Localization Data
UniProtKB/SwissProtQ5EAK4ATP-dependent DNA helicase tlh1
ArrayExpressQ5EAK4Link to ArrayExpress
UniProtKB/SwissProtQ1RKN3ATP-dependent DNA helicase tlh2
ArrayExpressQ1RKN3Link to ArrayExpress
RefSeq PeptideNP_595040RecQ type DNA helicase
RefSeq_mRNA_predictedXM_001713106972h- RecQ type DNA helicase Tlh1 (tlh2), mRNA
RefSeq_peptide_predictedXP_001713158RecQ type DNA helicase Tlh1
European Nucleotide ArchiveBK005597ENA EMBL mapping
European Nucleotide ArchiveBX784043ENA EMBL mapping
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveCAC05745ENA Protein Mapping
European Nucleotide ArchiveCAJ90629ENA Protein Mapping
European Nucleotide ArchiveCAO77679ENA Protein Mapping
European Nucleotide ArchiveDAA05660ENA Protein Mapping
UniParcUPI0000D5BE23UniProt Archive

Literature for tlh2

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Search: UK PMC or PubMed