rsv1 (SPBP4H10.09)

Gene Standard Namersv1 Characterisation Statuspublished
Systematic IDSPBP4H10.09 Feature Typeprotein coding
Synonyms Name Description
Producttranscription factor Rsv1 Product Size428aa, 46.82 kDa
Genomic Location Chromosome II, 2888450-2889979 (1530nt); CDS:2888450-2889736 (1287nt)

Ensembl Gene Location
GO Molecular Function
GO Biological Process
Term NameCount
cellular response to glucose starvation6
Annotation ExtensionEvidenceWith/FromReference
regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle6
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
mitotic spindle271
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
decreased cell population growth on glucose carbon sourcersv1+ (wild type)380
normal spore germination frequencyrsv1Δ13
normal vegetative cell population growthrsv1Δ813
sensitive to hydroxyurearsv1Δ594
sensitive to thiabendazolersv1Δ329
viable vegetative cell populationrsv1Δ3850

Cell Phenotype

Term NameGenotypesCount
increased level of carbohydrate metabolism gene mRNA during meiotic cell cyclersv1Δ1
normal spore morphologyrsv1Δ18
viable vegetative cell with normal cell morphologyrsv1Δ3102
Target Of
FYPO affected by mutation in mei4 meiotic forkhead transcription factor Mei4
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
3' UTR2889737..2889979AF016222
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
SM00355 SMART IPR015880 Zinc finger, C2H2-like 4 26 19
SM00355 SMART IPR015880 Zinc finger, C2H2-like 32 56 19
PS50157 Prosite Profiles IPR007087 Zinc finger, C2H2 4 31 20
PS50157 Prosite Profiles IPR007087 Zinc finger, C2H2 32 61 20
PS00028 Prosite Patterns IPR007087 Zinc finger, C2H2 34 56 28
PS00028 Prosite Patterns IPR007087 Zinc finger, C2H2 6 26 28
PTHR24409 HMMPANTHER 2 58 7 Gene3D IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain 24 57 15 Gene3D IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain 2 23 15
SSF57667 SuperFamily 2 56 26

View domain organization at Pfam

Term IDTerm NameReferenceCount
PBO:0000137zinc finger proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000137
PBO:0000153zf-C2H2 typeTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000153

Protein Properties

Ave. residue weight 109.38 Da
Charge 23.00
Codon Adaptation Index 0.43
Isoelectric point 10.15
Molecular weight 46.82 kDa
Number of residues 428
Gene Expression

Qualitative Gene Expression

RNA levelincreased during GO:0042149quantitative PCRPMID:25411338

Quantitative Gene Expression

View graphical display of gene expression data for rsv1 (SPBP4H10.09)

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.36during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
0.65during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
deletion mutant expression profiling PMID:1792781179
Taxonomic Conservation
conserved in fungi only616
conserved in fungi4607
conserved in eukaryotes4517

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Load genes that interact physically with SPBP4H10.09 into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
binds DNA-binding domain construct withSPBC16G5.16transcription factor, zf-fungal binuclear cluster type (predicted) Two-hybridPMID:26771498
binds DNA-binding domain construct withpat1serine/threonine protein kinase Ran1/Pat1 Two-hybridPMID:26771498
modified bylkh1dual specificity protein kinase Lkh1 Biochemical ActivityPMID:26167880
Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPBP4H10.09 into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
enhances phenotype ofmst2histone acetyltransferase Mst2 Phenotypic EnhancementPMID:19547744
enhances phenotype ofpst2Clr6 histone deacetylase complex subunit Pst2 Phenotypic EnhancementPMID:19547744
rescuessac32nuclear export factor Sac32 (predicted) Phenotypic SuppressionPMID:19547744
External References
Database Identifier Description
NBRP SPBP4H10.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBP4H10.09 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBP4H10.09 BioGRID Interaction Datasets
Expression Viewer SPBP4H10.09 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBP4H10.09 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBP4H10.09 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBP4H10.09 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBP4H10.09 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBP4H10.09 Transcriptome Viewer (Bähler Lab)
GEO SPBP4H10.09 GEO profiles
PInt SPBP4H10.09 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBP4H10.09 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPBP4H10.09 Fission yeast phenotypic data & analysis
Cyclebase SPBP4H10.09.1 Cell Cycle Data
SPD / RIKEN32/32G06Orfeome Localization Data
UniProtKB/SwissProtQ9P7D9Zinc finger protein rsv1
ModBaseQ9P7D9Database of comparative protein structure models
STRINGQ9P7D9Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596183transcription factor Rsv1
RefSeq mRNANM_001022102972h- transcription factor Rsv1 (rsv1), mRNA
European Nucleotide ArchiveAAB87047.1ENA Protein Mapping
European Nucleotide ArchiveCAB83167.1ENA Protein Mapping
UniParcUPI0000135229UniProt Archive

Literature for rsv1

Search: Europe PMC or PubMed

Release Version: PomBase:30_61 - 12 Sep 2016