rsv1 (SPBP4H10.09)


Gene Standard Namersv1 Characterisation Statuspublished
Systematic IDSPBP4H10.09 Feature Typeprotein coding
Synonyms Name Description
Producttranscription factor Rsv1 Product Size428aa, 46.82 kDa
Genomic Location Chromosome II, 2888450-2889979 (1530nt); CDS:2888450-2889736 (1287nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingNASGO_REF:000005194
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcriptionIMPPMID:179278119
GO:0046872metal ion bindingIEAUniProtKB-KW:KW-0479GO_REF:0000037748
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0042149cellular response to glucose starvation7
requiredIMPPMID:9372444
GO:0010678negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templatedIMPPMID:179278111
GO:0000122negative regulation of transcription from RNA polymerase II promoter78
during meiotic cell cycleIMPPMID:17927811
GO:0006366transcription from RNA polymerase II promoterIMPPMID:17927811139
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0072686mitotic spindleIDAPMID:16823372254
GO:0005634nucleusIDAPMID:168233722737
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0000088sensitive to hydroxyureaCell growth assayrsv1ΔNullPECO:0000137, PECO:0000005PMID:23173672513
FYPO:0000091sensitive to thiabendazoleCell growth assayrsv1ΔNullPECO:0000137, PECO:0000005PMID:23173672175
FYPO:0002060viable vegetative cell populationMicroscopyrsv1ΔNullPMID:204732893751
Microscopynot recorded (unrecorded)PMID:17927811
Microscopyrsv1ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyrsv1ΔNullPECO:0000005, PECO:0000137PMID:23697806
Target Of
OntologyRelationshipGeneProductReference
GO regulated by mei4 meiotic forkhead transcription factor Mei4 PMID:17927811
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
128884502889979
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF13465 Pfam 21 45 9
SM00355 SMART IPR015880 Zinc finger, C2H2-like 32 56 19
SM00355 SMART IPR015880 Zinc finger, C2H2-like 4 26 19
PS00028 Prosite Patterns IPR007087 Zinc finger, C2H2 6 26 28
PS00028 Prosite Patterns IPR007087 Zinc finger, C2H2 34 56 28
PS50157 Prosite Profiles IPR007087 Zinc finger, C2H2 32 61 20
PS50157 Prosite Profiles IPR007087 Zinc finger, C2H2 4 31 20
PTHR10042 HMMPANTHER 4 65 3
3.30.160.60 Gene3D IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain 2 23 15
3.30.160.60 Gene3D IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain 24 57 15
SSF57667 SuperFamily 2 56 26

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000137zinc finger proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000137
PBO:0000153zf-C2H2 typeTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000153

Protein Properties

Ave. residue weight 109.38 Da
Charge 23.00
Isoelectric point 10.15
Molecular weight 46.82 kDa
Number of residues 428
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
NDduring GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.36during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.65during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Misc
DescriptionQualifierReferenceCount
deletion mutant expression profiling PMID:1792781178
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi only620
conserved in fungi4599
conserved in eukaryotes4514
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
mst2histone acetyltransferase Mst2 Phenotypic EnhancementPMID:19547744
SPCC70.06nuclear export factor (predicted) Phenotypic SuppressionPMID:19547744
pst2Clr6 histone deacetylase complex subunit Pst2 Phenotypic EnhancementPMID:19547744
External References
Database Identifier Description
NBRP SPBP4H10.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBP4H10.09 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBP4H10.09 BioGRID Interaction Datasets
Expression Viewer SPBP4H10.09 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBP4H10.09 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBP4H10.09 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBP4H10.09 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBP4H10.09 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBP4H10.09 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBP4H10.09 Cell Cycle Data
GEO SPBP4H10.09 GEO profiles
PInt SPBP4H10.09 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPBP4H10.09 Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN32/32G06Orfeome Localization Data
UniProtKB/SwissProtQ9P7D9Zinc finger protein rsv1
ModBaseQ9P7D9Database of comparative protein structure models
STRINGQ9P7D9Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_596183transcription factor Rsv1
RefSeq mRNANM_001022102972h- transcription factor Rsv1 (rsv1), mRNA
European Nucleotide ArchiveAAB87047.1ENA Protein Mapping
European Nucleotide ArchiveCAB83167.1ENA Protein Mapping
UniParcUPI0000135229UniProt Archive

Literature for rsv1

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014