rpp201 (SPBP8B7.06)


Gene Standard Namerpp201 Characterisation Statuspublished
Systematic IDSPBP8B7.06 Feature Typeprotein coding
Synonymsrpa2, rpp2, rpp2-1 Name Description
Product60S acidic ribosomal protein A2 Product Size110aa, 11.16 kDa
Genomic Location Chromosome II, 3643177-3643653 (477nt); CDS:3643189-3643584 (396nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003735structural constituent of ribosomeISOSGD:S000005399GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002182cytoplasmic translational elongationNASGO_REF:0000051193
GO:0006414translational elongationISOSGD:S000005399GO_REF:0000024221
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722316
GO:0022625cytosolic large ribosomal subunitISOSGD:S000005399GO_REF:000002482
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001234slow vegetative cell population growthCell growth assayrpa2-Not specifiedPMID:232565554
FYPO:0002060viable vegetative cell populationMicroscopyrpp201ΔNullPMID:204732893760
Microscopyrpp201ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001491viable vegetative cellCell growth assayrpa2-Not specifiedPMID:23256553592
FYPO:0002177viable vegetative cell with normal cell morphology3086
penetrance FYPO_EXT:0000001Microscopyrpp201ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
136431773643497
236435613643653

UTRs

Region Coordinates Reference
five_prime_UTR3643177..3643188PMID:21511999
three_prime_UTR3643585..3643653PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00428 Pfam IPR001813 Ribosomal protein L10/L12 17 109 7
PTHR21141 HMMPANTHER 1 110 8
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 82 96 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 97 108 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 21 32 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 36 47 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 101.44 Da
Charge -17.00
Isoelectric point 3.69
Molecular weight 11.16 kDa
Number of residues 110
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineS100PMID:217125471663
present during mitotic M phase
present during mitotic M phaseS28PMID:21712547
MOD:00696phosphorylated residueNASPMID:195477441915
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
532063during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
513386during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
566086during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
633373during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
78738.88during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
147874.99during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
494436during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
95during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
8.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in archaea237
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ams2cell cycle regulated GATA-type transcription factor Ams2 Negative GeneticPMID:22681890
SPAC343.04cWD repeat protein, human WDR26 family, ubiquitin ligase complex subunit (predicted) Positive GeneticPMID:22681890
snu66U4/U6 x U5 tri-snRNP complex subunit Snu66 Negative GeneticPMID:22681890
prp4serine/threonine protein kinase Prp4 Negative GeneticPMID:22681890
SPAC513.07flavonol reductase/cinnamoyl-CoA reductase family Negative GeneticPMID:22681890
vps17retromer complex subunit Vps17 Negative GeneticPMID:22681890
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
pab2poly(A) binding protein Pab2 Negative GeneticPMID:22681890
swd1Set1C complex subunit Swd1 Negative GeneticPMID:22681890
pek1MAP kinase kinase Pek1 Negative GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
gst1glutathione S-transferase Gst1 Negative GeneticPMID:22681890
SPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:22681890
ppk9serine/threonine protein kinase Ppk9 (predicted) Negative GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
sty1MAP kinase Sty1 Negative GeneticPMID:22681890
rad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
atg6beclin family protein, involved in autophagy Positive GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
clr1cryptic loci regulator Clr1 Negative GeneticPMID:22681890
atp11F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Positive GeneticPMID:22681890
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:22681890
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
Negative GeneticPMID:22681890
pub3HECT-type ubiquitin-protein ligase Pub3 (predicted) Negative GeneticPMID:22681890
par1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:22681890
hrp3ATP-dependent DNA helicase Hrp3 Positive GeneticPMID:22681890
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
sfp1transcription factor Sfp1 (predicted) Negative GeneticPMID:22681890
nro1negative regulator of Ofd1, Nro1 Negative GeneticPMID:22681890
dsc5UBX domain containing protein required for Sre1 cleavage Negative GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
tps2trehalose-phosphate synthase Tps2 (predicted) Positive GeneticPMID:22681890
prz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
tps1alpha,alpha-trehalose-phosphate synthase Negative GeneticPMID:22681890
elp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
gma12alpha-1,2-galactosyltransferase Gma12 Negative GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
External References
Database Identifier Description
NBRP SPBP8B7.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBP8B7.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBP8B7.06 BioGRID Interaction Datasets
Expression Viewer SPBP8B7.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBP8B7.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBP8B7.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBP8B7.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBP8B7.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBP8B7.06 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBP8B7.06 Cell Cycle Data
GEO SPBP8B7.06 GEO profiles
PInt SPBP8B7.06 Protein-Protein Interaction Predictor (Bähler Lab)
EntrezGene254129660S acidic ribosomal protein P2A subunit
WikiGene254129660S acidic ribosomal protein P2A subunit
SPD / RIKEN31/31D03Orfeome Localization Data
UniProtKB/SwissProtP0809460S acidic ribosomal protein P2-alpha
ModBaseP08094Database of comparative protein structure models
STRINGP08094Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59651360S acidic ribosomal protein P2A subunit
RefSeq mRNANM_001022434972h- 60S acidic ribosomal protein P2A subunit (rpp201), mRNA
European Nucleotide ArchiveY00466ENA EMBL mapping
European Nucleotide ArchiveAAA35335ENA Protein Mapping
European Nucleotide ArchiveAAA35335.1ENA Protein Mapping
European Nucleotide ArchiveCAA21791ENA Protein Mapping
European Nucleotide ArchiveCAA21791.1ENA Protein Mapping
European Nucleotide ArchiveCAA68528ENA Protein Mapping
UniParcUPI0000134260UniProt Archive

Literature for rpp201

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014