rpp201 (SPBP8B7.06)


Gene Standard Namerpp201 Characterisation Statuspublished
Systematic IDSPBP8B7.06 Feature Typeprotein coding
Synonymsrpa2, rpp2, rpp2-1 Name Description
Product60S acidic ribosomal protein A2 Product Size110aa, 11.16 kDa
Genomic Location Chromosome II, 3643177-3643653 (477nt); CDS:3643189-3643584 (396nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003735structural constituent of ribosomeISOSGD:S000005399GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002182cytoplasmic translational elongationNASGO_REF:0000051193
GO:0006414translational elongationISOSGD:S000005399GO_REF:0000024221
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722317
GO:0022625cytosolic large ribosomal subunitISOSGD:S000005399GO_REF:000002482
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001234slow vegetative cell population growthCell growth assayrpa2-Not specifiedPMID:232565540
FYPO:0002060viable vegetative cell populationMicroscopyrpp201ΔNullPMID:204732893755
Microscopyrpp201ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001491viable vegetative cellCell growth assayrpa2-Not specifiedPMID:23256553271
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopyrpp201ΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
136431773643497
236435613643653

UTRs

Region Start End Reference
three_prime_UTR36435853643653PMID:21511999
five_prime_UTR36431773643188PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00428 Pfam IPR001813 Ribosomal protein L10/L12 17 109 7
PTHR21141 HMMPANTHER 1 110 8
Low complexity (SEG) seg 70 103
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 36 47 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 21 32 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 97 108 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 82 96 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 101.44 Da
Charge -17.00
Isoelectric point 3.69
Molecular weight 11.16 kDa
Number of residues 110
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00696phosphorylated residuePMID:195477441192
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
78738.88during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
147874.99during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
95during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
8.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in archaea237
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ams2cell cycle regulated GATA-type transcription factor Ams2 Negative GeneticPMID:22681890
SPAC343.04cWD repeat protein, human WDR26 family, ubiquitin ligase complex subunit (predicted) Positive GeneticPMID:22681890
snu66U4/U6 x U5 tri-snRNP complex subunit Snu66 Negative GeneticPMID:22681890
prp4serine/threonine protein kinase Prp4 Negative GeneticPMID:22681890
SPAC513.07flavonol reductase/cinnamoyl-CoA reductase family Negative GeneticPMID:22681890
vps17retromer complex subunit Vps17 Negative GeneticPMID:22681890
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
pab2poly(A) binding protein Pab2 Negative GeneticPMID:22681890
swd1Set1C complex subunit Swd1 Negative GeneticPMID:22681890
pek1MAP kinase kinase Pek1 Negative GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
gst1glutathione S-transferase Gst1 Negative GeneticPMID:22681890
SPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:22681890
ppk9serine/threonine protein kinase Ppk9 (predicted) Negative GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
sty1MAP kinase Sty1 Negative GeneticPMID:22681890
rad55RecA family ATPase Rad55/Rhp55 Negative GeneticPMID:22681890
atg6beclin family protein, involved in autophagy Positive GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
clr1cryptic loci regulator Clr1 Negative GeneticPMID:22681890
atp11F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Positive GeneticPMID:22681890
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:22681890
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
Negative GeneticPMID:22681890
pub3HECT-type ubiquitin-protein ligase Pub3 (predicted) Negative GeneticPMID:22681890
par1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:22681890
hrp3ATP-dependent DNA helicase Hrp3 Positive GeneticPMID:22681890
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
sfp1transcription factor Sfp1 (predicted) Negative GeneticPMID:22681890
nro1negative regulator of Ofd1, Nro1 Negative GeneticPMID:22681890
dsc5UBX domain containing protein required for Sre1 cleavage Negative GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
tps2trehalose-phosphate synthase Tps2 (predicted) Positive GeneticPMID:22681890
prz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
tps1alpha,alpha-trehalose-phosphate synthase Negative GeneticPMID:22681890
elp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
gma12alpha-1,2-galactosyltransferase Gma12 Negative GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPBP8B7.06 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPBP8B7.06 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPBP8B7.06 BioGRID Interaction Datasets
Expression Viewer SPBP8B7.06 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPBP8B7.06 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPBP8B7.06 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPBP8B7.06 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPBP8B7.06 Polyadenylation Viewer (Gullerova lab)
pombeTV SPBP8B7.06 Transcriptome Viewer (Bähler Lab)
Cyclebase SPBP8B7.06 Cell Cycle Data
GEO SPBP8B7.06 GEO profiles
PInt SPBP8B7.06 Protein-Protein Interaction Predictor (Bähler Lab)
EntrezGene254129660S acidic ribosomal protein P2A subunit
WikiGene254129660S acidic ribosomal protein P2A subunit
SPD / RIKEN31/31D03Orfeome Localization Data
UniProtKB/SwissProtP0809460S acidic ribosomal protein P2-alpha
ModBaseP08094Database of comparative protein structure models
StringP08094Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59651360S acidic ribosomal protein P2A subunit
RefSeq mRNANM_001022434972h- 60S acidic ribosomal protein P2A subunit (rpp201), mRNA
European Nucleotide ArchiveAAA35335ENA Protein Mapping
European Nucleotide ArchiveCAA21791ENA Protein Mapping
European Nucleotide ArchiveCAA68528ENA Protein Mapping
UniParcUPI0000134260UniProt Archive

Literature for rpp201

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014